CA2706730C - Systeme therapeutique a liberation controlee a monocouche - Google Patents

Systeme therapeutique a liberation controlee a monocouche Download PDF

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Publication number
CA2706730C
CA2706730C CA2706730A CA2706730A CA2706730C CA 2706730 C CA2706730 C CA 2706730C CA 2706730 A CA2706730 A CA 2706730A CA 2706730 A CA2706730 A CA 2706730A CA 2706730 C CA2706730 C CA 2706730C
Authority
CA
Canada
Prior art keywords
therapeutic system
controlled release
release therapeutic
poly
dosage form
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CA2706730A
Other languages
English (en)
Other versions
CA2706730A1 (fr
Inventor
Rasik Patel
Naresh Talwar
Vinayak Pathak
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pharmascience Inc
Original Assignee
Pharmascience Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmascience Inc filed Critical Pharmascience Inc
Priority to CA2706730A priority Critical patent/CA2706730C/fr
Publication of CA2706730A1 publication Critical patent/CA2706730A1/fr
Application granted granted Critical
Publication of CA2706730C publication Critical patent/CA2706730C/fr
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/167—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface
    • A61K9/1676—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface having a drug-free core with discrete complete coating layer containing drug

Landscapes

  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

La présente invention concerne un système thérapeutique à libération contrôlée, son procédé de fabrication ainsi qu'une forme pharmaceutique contenant ledit système thérapeutique à libération contrôlée. Le système thérapeutique à libération contrôlée comprend : un noyau inerte; et une couche d'enrobage disposée sur le noyau inerte, ladite couche d'enrobage comprenant : une matrice polymère contrôlant la libération dans laquelle un agent pharmaceutiquement actif est distribué.
CA2706730A 2007-12-17 2008-12-15 Systeme therapeutique a liberation controlee a monocouche Expired - Fee Related CA2706730C (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CA2706730A CA2706730C (fr) 2007-12-17 2008-12-15 Systeme therapeutique a liberation controlee a monocouche

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
CA002615137A CA2615137A1 (fr) 2007-12-17 2007-12-17 Dispositif therapeutique monocouche a liberation controlee
CA2,615,137 2007-12-17
CA2706730A CA2706730C (fr) 2007-12-17 2008-12-15 Systeme therapeutique a liberation controlee a monocouche
PCT/CA2008/002165 WO2009076754A1 (fr) 2007-12-17 2008-12-15 Système thérapeutique à libération contrôlée à monocouche

Publications (2)

Publication Number Publication Date
CA2706730A1 CA2706730A1 (fr) 2009-06-25
CA2706730C true CA2706730C (fr) 2016-10-18

Family

ID=40792428

Family Applications (2)

Application Number Title Priority Date Filing Date
CA002615137A Abandoned CA2615137A1 (fr) 2007-12-17 2007-12-17 Dispositif therapeutique monocouche a liberation controlee
CA2706730A Expired - Fee Related CA2706730C (fr) 2007-12-17 2008-12-15 Systeme therapeutique a liberation controlee a monocouche

Family Applications Before (1)

Application Number Title Priority Date Filing Date
CA002615137A Abandoned CA2615137A1 (fr) 2007-12-17 2007-12-17 Dispositif therapeutique monocouche a liberation controlee

Country Status (2)

Country Link
CA (2) CA2615137A1 (fr)
WO (1) WO2009076754A1 (fr)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2356984A1 (fr) * 2010-02-04 2011-08-17 Nycomed Austria GmbH Formulation améliorée de bromure de distigmine
ES2938609T3 (es) 2017-09-20 2023-04-13 Tillotts Pharma Ag Preparación de formas farmacéuticas sólidas que comprenden anticuerpos mediante estratificación de solución/suspensión
CN109464703B (zh) * 2018-11-29 2021-02-26 浙江瑞谷生物科技有限公司 一种骨修复材料及其制备方法和应用

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE426548B (sv) * 1978-12-05 1983-01-31 Haessle Ab Fast farmaceutisk beredning innehallande en terapeutiskt effektiv hjertglykosid och en polymer
US4758437A (en) * 1981-12-23 1988-07-19 Yamanouchi Pharmaceutical Co., Ltd. Composition for long acting nicardipine preparation and process of producing the composition
CA1338596C (fr) * 1988-09-27 1996-09-17 Hiroyoshi Koyama Granules possedant un noyau et leur production
EP0452862B1 (fr) * 1990-04-18 1995-07-19 Asahi Kasei Kogyo Kabushiki Kaisha Noyaux des germes sphériques, granules sphériques et procédé de leur préparation
EP1140105B1 (fr) * 1998-12-24 2003-10-22 Janssen Pharmaceutica N.V. Composition de galantamine a liberation controlee
DE10353196A1 (de) * 2003-11-13 2005-06-16 Röhm GmbH & Co. KG Mehrschichtige Arzneiform mit einer die Abgabe einer modulatorischen Substanz beeinflussenden Matrix
WO2006102965A1 (fr) * 2005-03-29 2006-10-05 Evonik Röhm Gmbh Forme pharmaceutique multiparticulaire constituee de pellets ayant une matrice qui agit sur la liberation d'une substance modulatrice

Also Published As

Publication number Publication date
WO2009076754A1 (fr) 2009-06-25
CA2706730A1 (fr) 2009-06-25
CA2615137A1 (fr) 2009-06-17

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Legal Events

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EEER Examination request

Effective date: 20131119

MKLA Lapsed

Effective date: 20210831

MKLA Lapsed

Effective date: 20191216