CA2783146C - Compositions et procedes d'encapsulation de vaccins aux fins de la vaccination orale des poissons et autres animaux et de l'administration de doses de rappel a ces derniers - Google Patents

Compositions et procedes d'encapsulation de vaccins aux fins de la vaccination orale des poissons et autres animaux et de l'administration de doses de rappel a ces derniers Download PDF

Info

Publication number
CA2783146C
CA2783146C CA2783146A CA2783146A CA2783146C CA 2783146 C CA2783146 C CA 2783146C CA 2783146 A CA2783146 A CA 2783146A CA 2783146 A CA2783146 A CA 2783146A CA 2783146 C CA2783146 C CA 2783146C
Authority
CA
Canada
Prior art keywords
chitosan
composition
immunogenic
solution
pharmaceutically active
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CA2783146A
Other languages
English (en)
Other versions
CA2783146A1 (fr
Inventor
Harel Moti
Brian Carpenter
Original Assignee
Intervet International BV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=46514232&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CA2783146(C) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from US13/466,279 external-priority patent/US8778384B2/en
Application filed by Intervet International BV filed Critical Intervet International BV
Publication of CA2783146A1 publication Critical patent/CA2783146A1/fr
Application granted granted Critical
Publication of CA2783146C publication Critical patent/CA2783146C/fr
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/0233—Rickettsiales, e.g. Anaplasma
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A61K39/145—Orthomyxoviridae, e.g. influenza virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/52—Bacterial cells; Fungal cells; Protozoal cells
    • A61K2039/521—Bacterial cells; Fungal cells; Protozoal cells inactivated (killed)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • A61K2039/541—Mucosal route
    • A61K2039/542—Mucosal route oral/gastrointestinal
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/55—Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
    • A61K2039/552—Veterinary vaccine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55555—Liposomes; Vesicles, e.g. nanoparticles; Spheres, e.g. nanospheres; Polymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55583—Polysaccharides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
    • A61K2039/6087—Polysaccharides; Lipopolysaccharides [LPS]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/70—Multivalent vaccine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011—Details
    • C12N2760/16011—Orthomyxoviridae
    • C12N2760/16034—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Virology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)

Abstract

Linvention concerne une composition comprenant un agent pharmaceutique actif et un système de distribution de bioadhésif pour ladministration par voie orale dun vaccin à des animaux, plus précisément des animaux aquatiques.
CA2783146A 2012-05-08 2012-07-16 Compositions et procedes d'encapsulation de vaccins aux fins de la vaccination orale des poissons et autres animaux et de l'administration de doses de rappel a ces derniers Active CA2783146C (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US13/466,279 US8778384B2 (en) 2008-03-24 2012-05-08 Compositions and methods for encapsulating vaccines for the oral vaccination and boostering of fish and other animals
US13/466,279 2012-05-08

Publications (2)

Publication Number Publication Date
CA2783146A1 CA2783146A1 (fr) 2013-11-08
CA2783146C true CA2783146C (fr) 2020-04-07

Family

ID=46514232

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2783146A Active CA2783146C (fr) 2012-05-08 2012-07-16 Compositions et procedes d'encapsulation de vaccins aux fins de la vaccination orale des poissons et autres animaux et de l'administration de doses de rappel a ces derniers

Country Status (5)

Country Link
EP (1) EP2662074B1 (fr)
CA (1) CA2783146C (fr)
CL (2) CL2012001995A1 (fr)
DK (1) DK2662074T3 (fr)
ES (1) ES2693539T3 (fr)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CL2015002907A1 (es) * 2015-09-29 2016-06-17 Univ Santiago Chile Vacuna oral contra isav que comprende nanopartículas de quitosán que encapsulan una virina del virus isa y nanoparticulas de quitosán que encapsulan un adyuvante que consiste en un adn que se codifica para la replicasa/transcriptasa de un alfavirus de salmón (replicón), proceso de preparación, método para tratar peces infectados con isav y método para estimular la respuesta inmune en peces.
EP3468530A4 (fr) 2016-06-10 2020-03-11 Clarity Cosmetics Inc. Formulations non comédogènes de soin des cheveux et du cuir chevelu et méthode d'utilisation
PT3589331T (pt) 2017-02-28 2021-07-22 Lument Ab Agente de contraste peroral negativo para tc abdominal
CN109172817B (zh) * 2018-08-16 2021-10-26 华中农业大学 猪流行性腹泻病毒减毒活疫苗壳聚糖微球的制备方法及其应用

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2105129B1 (fr) * 2008-03-24 2018-01-17 Intervet International B.V. Vaccins encapsulés pour la vaccination orale et la stimulation des poissons et autres animaux
WO2010111565A2 (fr) * 2009-03-27 2010-09-30 Advanced Bionutrition Corporation Vaccins microparticulaires utilisables pour procéder à une vaccination et à des rappels par voie orale ou nasale chez les animaux, dont les poissons

Also Published As

Publication number Publication date
EP2662074B1 (fr) 2018-09-26
CL2015003104A1 (es) 2016-06-24
EP2662074A1 (fr) 2013-11-13
DK2662074T3 (en) 2018-12-10
CA2783146A1 (fr) 2013-11-08
ES2693539T3 (es) 2018-12-12
CL2012001995A1 (es) 2012-12-14

Similar Documents

Publication Publication Date Title
EP2105129B1 (fr) Vaccins encapsulés pour la vaccination orale et la stimulation des poissons et autres animaux
EP3266448B1 (fr) Vaccins microparticulaires utilisables pour procéder à une vaccination et à des rappels par voie orale ou nasale chez les animaux, dont les poissons
Sun et al. Polysaccharides as vaccine adjuvants
CN102257011B (zh) 通过酵母细胞的碱水解和酸水解生产包含葡聚糖和甘露聚糖的糖类组合物
Liang et al. Progress and prospect of polysaccharides as adjuvants in vaccine development
JP5675798B2 (ja) バイオポリマーハイブリッドゲルデポー送達システム
JPH05503285A (ja) グルカン配達系及び補薬
US9205151B2 (en) Compositions and methods for encapsulating vaccines for the oral vaccination and boostering of fish and other animals
CA2783146C (fr) Compositions et procedes d'encapsulation de vaccins aux fins de la vaccination orale des poissons et autres animaux et de l'administration de doses de rappel a ces derniers
CN105916493A (zh) 用于经口递送生物活性剂的组合物
Behera et al. Antigen adsorbed surface modified poly-ɛ-caprolactone microspheres stimulates both adaptive and innate immune response in fish
CN107847439A (zh) 用于舌下施用的吡喃葡萄糖基脂质a和过敏原制剂
EP3471706B1 (fr) Composition pharmaceutique orale comprenant un agent pharmaceutiquement actif, au moins un polymère bioadhésif cationique et au moins deux polymères anioniques
Yadav et al. Application of natural polysaccharide for delivery of biopharmaceuticals.
KR101094816B1 (ko) 키토산 나노입자를 포함하는 과실의 칼슘 흡수 촉진용기능성 식품 조성물
US20030124192A1 (en) Pharmaceutical compositions and their preparation
Suksamran Development of microparticles with entrapped dust mite allergen extract

Legal Events

Date Code Title Description
EEER Examination request

Effective date: 20170627

MPN Maintenance fee for patent paid

Free format text: FEE DESCRIPTION TEXT: MF (PATENT, 13TH ANNIV.) - STANDARD

Year of fee payment: 13

U00 Fee paid

Free format text: ST27 STATUS EVENT CODE: A-4-4-U10-U00-U101 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: MAINTENANCE REQUEST RECEIVED

Effective date: 20250612

U11 Full renewal or maintenance fee paid

Free format text: ST27 STATUS EVENT CODE: A-4-4-U10-U11-U102 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: MAINTENANCE FEE PAYMENT PAID IN FULL

Effective date: 20250612