CA2879093C - Complexes bis-iridium pour la fabrication d'etiquettes-livrets - Google Patents

Complexes bis-iridium pour la fabrication d'etiquettes-livrets Download PDF

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Publication number
CA2879093C
CA2879093C CA2879093A CA2879093A CA2879093C CA 2879093 C CA2879093 C CA 2879093C CA 2879093 A CA2879093 A CA 2879093A CA 2879093 A CA2879093 A CA 2879093A CA 2879093 C CA2879093 C CA 2879093C
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alkyl
substituted
aryl
aryloxy
sulfo
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CA2879093A1 (fr
Inventor
Robert CYSEWSKI
Luisa De Cola
Jesus Miguel Fernandez Hernandez
Hans-Peter Josel
Elena LONGHI
Gaston Hubertus Maria VONDENHOFF
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F Hoffmann La Roche AG
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F Hoffmann La Roche AG
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F15/00—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
    • C07F15/0006—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table compounds of the platinum group
    • C07F15/0033—Iridium compounds
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09K—MATERIALS FOR MISCELLANEOUS APPLICATIONS, NOT PROVIDED FOR ELSEWHERE
    • C09K11/00—Luminescent materials, e.g. electroluminescent or chemiluminescent
    • C09K11/06—Luminescent materials, e.g. electroluminescent or chemiluminescent containing organic luminescent materials
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531—Production of immunochemical test materials
    • G01N33/532—Production of labelled immunochemicals
    • G01N33/533—Production of labelled immunochemicals with fluorescent label
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/582—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label
    • H—ELECTRICITY
    • H10—SEMICONDUCTOR DEVICES; ELECTRIC SOLID-STATE DEVICES NOT OTHERWISE PROVIDED FOR
    • H10K—ORGANIC ELECTRIC SOLID-STATE DEVICES
    • H10K85/00—Organic materials used in the body or electrodes of devices covered by this subclass
    • H10K85/30—Coordination compounds
    • H10K85/341—Transition metal complexes, e.g. Ru(II)polypyridine complexes
    • H10K85/342—Transition metal complexes, e.g. Ru(II)polypyridine complexes comprising iridium
    • H—ELECTRICITY
    • H10—SEMICONDUCTOR DEVICES; ELECTRIC SOLID-STATE DEVICES NOT OTHERWISE PROVIDED FOR
    • H10K—ORGANIC ELECTRIC SOLID-STATE DEVICES
    • H10K85/00—Organic materials used in the body or electrodes of devices covered by this subclass
    • H10K85/30—Coordination compounds
    • H10K85/361—Polynuclear complexes, i.e. complexes comprising two or more metal centers
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09K—MATERIALS FOR MISCELLANEOUS APPLICATIONS, NOT PROVIDED FOR ELSEWHERE
    • C09K2211/00—Chemical nature of organic luminescent or tenebrescent compounds
    • C09K2211/10—Non-macromolecular compounds
    • C09K2211/1003—Carbocyclic compounds
    • C09K2211/1007—Non-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09K—MATERIALS FOR MISCELLANEOUS APPLICATIONS, NOT PROVIDED FOR ELSEWHERE
    • C09K2211/00—Chemical nature of organic luminescent or tenebrescent compounds
    • C09K2211/10—Non-macromolecular compounds
    • C09K2211/1018—Heterocyclic compounds
    • C09K2211/1025—Heterocyclic compounds characterised by ligands
    • C09K2211/1029—Heterocyclic compounds characterised by ligands containing one nitrogen atom as the heteroatom
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09K—MATERIALS FOR MISCELLANEOUS APPLICATIONS, NOT PROVIDED FOR ELSEWHERE
    • C09K2211/00—Chemical nature of organic luminescent or tenebrescent compounds
    • C09K2211/18—Metal complexes
    • C09K2211/185—Metal complexes of the platinum group, i.e. Os, Ir, Pt, Ru, Rh or Pd
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2458/00—Labels used in chemical analysis of biological material
    • G01N2458/30—Electrochemically active labels
    • H—ELECTRICITY
    • H10—SEMICONDUCTOR DEVICES; ELECTRIC SOLID-STATE DEVICES NOT OTHERWISE PROVIDED FOR
    • H10K—ORGANIC ELECTRIC SOLID-STATE DEVICES
    • H10K50/00—Organic light-emitting devices
    • H10K50/10—OLEDs or polymer light-emitting diodes [PLED]
    • H10K50/11—OLEDs or polymer light-emitting diodes [PLED] characterised by the electroluminescent [EL] layers

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Organic Chemistry (AREA)
  • Materials Engineering (AREA)
  • Physics & Mathematics (AREA)
  • Inorganic Chemistry (AREA)
  • Biotechnology (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • High Energy & Nuclear Physics (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Electrochromic Elements, Electrophoresis, Or Variable Reflection Or Absorption Elements (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Electroluminescent Light Sources (AREA)

Abstract

Cette invention concerne de nouveaux complexes à base de bis-iridium (III), des marqueurs préparés à l'aide desdits complexes et un procédé de préparation desdits complexes.
CA2879093A 2012-08-02 2013-08-02 Complexes bis-iridium pour la fabrication d'etiquettes-livrets Active CA2879093C (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP12179056 2012-08-02
EP12179056.2 2012-08-02
PCT/EP2013/002324 WO2014019710A1 (fr) 2012-08-02 2013-08-02 Nouveaux complexes de bis-iridium pour préparer des marqueurs pour électrochimiluminescence (ecl)

Publications (2)

Publication Number Publication Date
CA2879093A1 CA2879093A1 (fr) 2014-02-06
CA2879093C true CA2879093C (fr) 2020-10-20

Family

ID=48917492

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2879093A Active CA2879093C (fr) 2012-08-02 2013-08-02 Complexes bis-iridium pour la fabrication d'etiquettes-livrets

Country Status (7)

Country Link
US (1) US10227366B2 (fr)
EP (1) EP2880043B1 (fr)
JP (1) JP6560120B2 (fr)
CN (1) CN104903335B (fr)
CA (1) CA2879093C (fr)
ES (1) ES2602206T3 (fr)
WO (1) WO2014019710A1 (fr)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2014019707A2 (fr) * 2012-08-02 2014-02-06 Roche Diagnostics Gmbh Nouveaux complexes à base d'iridium pour ecl
WO2014019708A1 (fr) * 2012-08-02 2014-02-06 Roche Diagnostics Gmbh Nouveaux complexes à base d'iridium pour électrochimiluminescence (ecl)
WO2017153574A1 (fr) 2016-03-11 2017-09-14 Roche Diagnostics Gmbh Amines à chaîne ramifiée utilisées dans la détection d'électrochimiluminescence
ES2944589T3 (es) 2016-08-25 2023-06-22 Hoffmann La Roche Nanopartículas de silicio multifuncionalizadas y usos de las mismas en procedimientos de detección basados en electroquimioluminiscencia

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Also Published As

Publication number Publication date
US20150148536A1 (en) 2015-05-28
CN104903335A (zh) 2015-09-09
JP6560120B2 (ja) 2019-08-14
CA2879093A1 (fr) 2014-02-06
CN104903335B (zh) 2018-05-18
JP2015527338A (ja) 2015-09-17
EP2880043B1 (fr) 2016-09-21
EP2880043A1 (fr) 2015-06-10
US10227366B2 (en) 2019-03-12
WO2014019710A1 (fr) 2014-02-06
HK1214601A1 (zh) 2016-07-29
ES2602206T3 (es) 2017-02-20

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