CA2892003A1 - Composes cycliques de cyclodextrine modifies comptant exactement deux fractions hydroxyle substituees par un acide amine aux fins d'une administration de produit therapeutique - Google Patents

Composes cycliques de cyclodextrine modifies comptant exactement deux fractions hydroxyle substituees par un acide amine aux fins d'une administration de produit therapeutique Download PDF

Info

Publication number: CA2892003A1
Authority: CA; Canada
Prior art keywords: polymer; cyclodextrin; occurrence; independently; compound
Prior art date: 2002-09-06
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Abandoned

Application number

CA2892003A

Other languages

English (en)

Inventor

Jianjun Cheng

Mark E. Davis

Kay T. Khin

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Dare Bioscience Inc

Original Assignee

Cerulean Pharma Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2002-09-06

Filing date

2003-09-04

Publication date

2004-03-18

2003-09-04 Application filed by Cerulean Pharma Inc filed Critical Cerulean Pharma Inc

2004-03-18 Publication of CA2892003A1 publication Critical patent/CA2892003A1/fr

Status Abandoned legal-status Critical Current

Links

HFHDHCJBZVLPGP-UHFFFAOYSA-N schardinger α-dextrin Chemical group O1C(C(C2O)O)C(CO)OC2OC(C(C2O)O)C(CO)OC2OC(C(C2O)O)C(CO)OC2OC(C(O)C2O)C(CO)OC2OC(C(C2O)O)C(CO)OC2OC2C(O)C(O)C1OC2CO HFHDHCJBZVLPGP-UHFFFAOYSA-N 0.000 title claims abstract description 224
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WHUUTDBJXJRKMK-VKHMYHEASA-N L-glutamic acid Chemical compound OC(=O)[C@@H](N)CCC(O)=O WHUUTDBJXJRKMK-VKHMYHEASA-N 0.000 claims abstract description 5
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229960000984 tocofersolan Drugs 0.000 description 1
JOXIMZWYDAKGHI-UHFFFAOYSA-M toluene-4-sulfonate Chemical compound CC1=CC=C(S([O-])(=O)=O)C=C1 JOXIMZWYDAKGHI-UHFFFAOYSA-M 0.000 description 1
238000011200 topical administration Methods 0.000 description 1
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229910052723 transition metal Inorganic materials 0.000 description 1
150000003624 transition metals Chemical class 0.000 description 1
230000004102 tricarboxylic acid cycle Effects 0.000 description 1
125000002469 tricosyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 description 1
125000005040 tridecenyl group Chemical group C(=CCCCCCCCCCCC)* 0.000 description 1
125000002889 tridecyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 description 1
JLGLQAWTXXGVEM-UHFFFAOYSA-N triethylene glycol monomethyl ether Chemical compound COCCOCCOCCO JLGLQAWTXXGVEM-UHFFFAOYSA-N 0.000 description 1
ITMCEJHCFYSIIV-UHFFFAOYSA-M triflate Chemical compound [O-]S(=O)(=O)C(F)(F)F ITMCEJHCFYSIIV-UHFFFAOYSA-M 0.000 description 1
238000013024 troubleshooting Methods 0.000 description 1
210000004881 tumor cell Anatomy 0.000 description 1
125000005065 undecenyl group Chemical group C(=CCCCCCCCCC)* 0.000 description 1
125000002948 undecyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 description 1
229960005486 vaccine Drugs 0.000 description 1
229940070710 valerate Drugs 0.000 description 1
NQPDZGIKBAWPEJ-UHFFFAOYSA-N valeric acid Chemical compound CCCCC(O)=O NQPDZGIKBAWPEJ-UHFFFAOYSA-N 0.000 description 1
235000015112 vegetable and seed oil Nutrition 0.000 description 1
235000019871 vegetable fat Nutrition 0.000 description 1
239000008158 vegetable oil Substances 0.000 description 1
229960000834 vinyl ether Drugs 0.000 description 1
210000001835 viscera Anatomy 0.000 description 1
239000003643 water by type Substances 0.000 description 1
229920003169 water-soluble polymer Polymers 0.000 description 1
230000003442 weekly effect Effects 0.000 description 1
238000004260 weight control Methods 0.000 description 1
238000010626 work up procedure Methods 0.000 description 1
230000029663 wound healing Effects 0.000 description 1
239000005019 zein Substances 0.000 description 1
229940093612 zein Drugs 0.000 description 1
239000011787 zinc oxide Substances 0.000 description 1
235000014692 zinc oxide Nutrition 0.000 description 1
239000002076 α-tocopherol Substances 0.000 description 1
235000004835 α-tocopherol Nutrition 0.000 description 1

Landscapes

Medicinal Preparation (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

CA2892003A 2002-09-06 2003-09-04 Composes cycliques de cyclodextrine modifies comptant exactement deux fractions hydroxyle substituees par un acide amine aux fins d'une administration de produit therapeutique Abandoned CA2892003A1 (fr)

Applications Claiming Priority (7)

Application Number	Priority Date	Filing Date	Title
US40885502P	2002-09-06	2002-09-06
US60/408,855		2002-09-06
US42283002P	2002-10-31	2002-10-31
US60/422,830		2002-10-31
US45199803P	2003-03-04	2003-03-04
US60/451,998		2003-03-04
CA2818071A CA2818071C (fr)	2002-09-06	2003-09-04	Composes cycliques de cyclodextrine modifies comptant exactement deux fractions hydroxyle substituees par un acide amine aux fins d'une administration de produit therapeutique

Related Parent Applications (1)

Application Number	Title	Priority Date	Filing Date
CA2818071A Division CA2818071C (fr)	2002-09-06	2003-09-04	Composes cycliques de cyclodextrine modifies comptant exactement deux fractions hydroxyle substituees par un acide amine aux fins d'une administration de produit therapeutique

Publications (1)

Publication Number	Publication Date
CA2892003A1 true CA2892003A1 (fr)	2004-03-18

Family

ID=35353386

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
CA2892003A Abandoned CA2892003A1 (fr)	2002-09-06	2003-09-04	Composes cycliques de cyclodextrine modifies comptant exactement deux fractions hydroxyle substituees par un acide amine aux fins d'une administration de produit therapeutique
CA2818071A Expired - Lifetime CA2818071C (fr)	2002-09-06	2003-09-04	Composes cycliques de cyclodextrine modifies comptant exactement deux fractions hydroxyle substituees par un acide amine aux fins d'une administration de produit therapeutique

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
CA2818071A Expired - Lifetime CA2818071C (fr)	2002-09-06	2003-09-04	Composes cycliques de cyclodextrine modifies comptant exactement deux fractions hydroxyle substituees par un acide amine aux fins d'une administration de produit therapeutique

Country Status (3)

Country	Link
CN (1)	CN1694728B (fr)
CA (2)	CA2892003A1 (fr)
ZA (1)	ZA200501848B (fr)

Cited By (2)

* Cited by examiner, † Cited by third party
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CN112675312A (zh) *	2020-12-30	2021-04-20	香港理工大学深圳研究院	一种脑靶向纳米递释系统及其制备方法
CN113855799A (zh) *	2021-10-21	2021-12-31	天津市人民医院	西达本胺联合利妥昔单抗在治疗老年复发难治性b细胞淋巴瘤疾病中的应用

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EP2277551B1 (fr)	2002-09-06	2013-05-08	Cerulean Pharma Inc.	Polymeres a base de cyclodextrine pour l'administration de medicament lies par liaison covalente
US20080176958A1 (en)	2007-01-24	2008-07-24	Insert Therapeutics, Inc.	Cyclodextrin-based polymers for therapeutics delivery
WO2009041666A1 (fr) *	2007-09-28	2009-04-02	Nanodex Inc.	Composé de cyclodextrine modifié par l'acide folique, procédé pour le produire, agent de délivrance de médicament pour le ciblage d'un système de délivrance de médicament, composition pharmaceutique et agent d'imagerie
US20120114658A1 (en) *	2009-09-15	2012-05-10	John Ryan	Treatment of cancer
EP2503888A4 (fr) *	2009-11-23	2015-07-29	Cerulean Pharma Inc	Polymères à base de cyclodextrine pour une administration thérapeutique
CN103037903A (zh) *	2010-05-18	2013-04-10	天蓝制药公司	用于治疗自身免疫性疾病或其它疾病的组合物和方法
CN102258788B (zh) *	2011-06-13	2012-11-07	南开大学	一种靶向传递阿霉素抗癌药的组装体及其制备方法
US20130196906A1 (en) *	2012-01-31	2013-08-01	Cerulean Pharma Inc.	Cyclodextrin-based polymers for therapeutic delivery
EP2826492A4 (fr) *	2012-03-13	2015-10-21	Postech Acad Ind Found	Conjugué d'administration de médicament conçu pour une libération prolongée et son utilisation
US20140094432A1 (en)	2012-10-02	2014-04-03	Cerulean Pharma Inc.	Methods and systems for polymer precipitation and generation of particles
EP2986646B1 (fr) *	2013-08-09	2019-04-10	Bio-rad Laboratories, Inc.	Détection de protéine au moyen de cyclodextrines modifiées
CN113777100B (zh) *	2021-08-27	2022-11-01	厦门大学	一种基于主客体作用的定量物质控释系统及方法
CN117645698B (zh) *	2024-01-29	2024-06-04	广东工业大学	一种两亲性21臂的光敏剂-前药星型聚合物及其制备方法和应用

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US6509323B1 (en) *	1998-07-01	2003-01-21	California Institute Of Technology	Linear cyclodextrin copolymers

2003
- 2003-09-04 CA CA2892003A patent/CA2892003A1/fr not_active Abandoned
- 2003-09-04 CA CA2818071A patent/CA2818071C/fr not_active Expired - Lifetime
- 2003-09-04 CN CN038248298A patent/CN1694728B/zh not_active Expired - Lifetime
2005
- 2005-05-03 ZA ZA200501848A patent/ZA200501848B/en unknown

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CN112675312A (zh) *	2020-12-30	2021-04-20	香港理工大学深圳研究院	一种脑靶向纳米递释系统及其制备方法
CN112675312B (zh) *	2020-12-30	2023-07-25	香港理工大学深圳研究院	一种脑靶向纳米递释系统及其制备方法
CN113855799A (zh) *	2021-10-21	2021-12-31	天津市人民医院	西达本胺联合利妥昔单抗在治疗老年复发难治性b细胞淋巴瘤疾病中的应用

Also Published As

Publication number	Publication date
ZA200501848B (en)	2006-06-28
CA2818071C (fr)	2015-08-18
CN1694728A (zh)	2005-11-09
CN1694728B (zh)	2011-12-28
CA2818071A1 (fr)	2004-03-18

Legal Events

Date	Code	Title	Description
2015-11-25	EEER	Examination request	Effective date: 20151120
2017-08-03	FZDE	Dead	Effective date: 20170622

Publication	Publication Date	Title
CA2497792C (fr)	2014-08-05	Polymeres a base de cyclodextrine pour administration de medicaments
CA2818071C (fr)	2015-08-18	Composes cycliques de cyclodextrine modifies comptant exactement deux fractions hydroxyle substituees par un acide amine aux fins d'une administration de produit therapeutique
AU2012247051B2 (en)	2015-02-19	Cyclodextrin-based polymers for therapeutics delivery
AU2013204984A1 (en)	2013-05-16	Cyclodextrin-based polymers for therapeutics delivery
HK1072202B (en)	2012-07-06	Cyclodextrin-based polymers for delivering the therapeutic agents covalently bound thereto
HK1151467B (en)	2014-01-03	Cyclodextrin-based polymers for delivering the therapeutic agents covalently bound thereto
HK1165305A (en)	2012-10-05	Cyclodextrin-based polymers for delivering the therapeutic agents covalently attached thereto
HK1165305B (en)	2018-10-12	Cyclodextrin-based polymers for delivering the therapeutic agents covalently attached thereto