ZA200501848B - Cyclodextrin-based polymers for delivering the therapeutic agents covalently bound thereto - Google Patents

Cyclodextrin-based polymers for delivering the therapeutic agents covalently bound thereto Download PDF

Info

Publication number: ZA200501848B
Authority: ZA; South Africa
Prior art keywords: polymer; cyclodextrin; compound; occurrence; independently
Prior art date: 2002-09-06

Application number

ZA200501848A

Other languages

English (en)

Inventor

Jianjun Cheng

Kay T Khin

Mark E David

Original Assignee

Insert Therapeutics Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2002-09-06

Filing date

2005-05-03

Publication date

2006-06-28

2005-05-03 Application filed by Insert Therapeutics Inc filed Critical Insert Therapeutics Inc

2006-06-28 Publication of ZA200501848B publication Critical patent/ZA200501848B/en

Links

229920000642 polymer Polymers 0.000 title claims description 359
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238000011200 topical administration Methods 0.000 description 1
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125000002469 tricosyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 description 1
125000005040 tridecenyl group Chemical group C(=CCCCCCCCCCCC)* 0.000 description 1
125000002889 tridecyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 description 1
JLGLQAWTXXGVEM-UHFFFAOYSA-N triethylene glycol monomethyl ether Chemical compound COCCOCCOCCO JLGLQAWTXXGVEM-UHFFFAOYSA-N 0.000 description 1
ITMCEJHCFYSIIV-UHFFFAOYSA-M triflate Chemical compound [O-]S(=O)(=O)C(F)(F)F ITMCEJHCFYSIIV-UHFFFAOYSA-M 0.000 description 1
238000013024 troubleshooting Methods 0.000 description 1
210000004881 tumor cell Anatomy 0.000 description 1
125000005065 undecenyl group Chemical group C(=CCCCCCCCCC)* 0.000 description 1
125000002948 undecyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 description 1
229960005486 vaccine Drugs 0.000 description 1
229940070710 valerate Drugs 0.000 description 1
NQPDZGIKBAWPEJ-UHFFFAOYSA-N valeric acid Chemical compound CCCCC(O)=O NQPDZGIKBAWPEJ-UHFFFAOYSA-N 0.000 description 1
235000015112 vegetable and seed oil Nutrition 0.000 description 1
235000019871 vegetable fat Nutrition 0.000 description 1
239000008158 vegetable oil Substances 0.000 description 1
229960000834 vinyl ether Drugs 0.000 description 1
210000001835 viscera Anatomy 0.000 description 1
239000003643 water by type Substances 0.000 description 1
229920003169 water-soluble polymer Polymers 0.000 description 1
230000003442 weekly effect Effects 0.000 description 1
238000004260 weight control Methods 0.000 description 1
238000010626 work up procedure Methods 0.000 description 1
230000029663 wound healing Effects 0.000 description 1
239000005019 zein Substances 0.000 description 1
229940093612 zein Drugs 0.000 description 1
239000011787 zinc oxide Substances 0.000 description 1
235000014692 zinc oxide Nutrition 0.000 description 1
239000002076 α-tocopherol Substances 0.000 description 1
235000004835 α-tocopherol Nutrition 0.000 description 1

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Medicinal Preparation (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

ZA200501848A 2002-09-06 2005-05-03 Cyclodextrin-based polymers for delivering the therapeutic agents covalently bound thereto ZA200501848B (en)

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Application Number	Priority Date	Filing Date	Title
US40885502P	2002-09-06	2002-09-06

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CN (1)	CN1694728B (fr)
CA (2)	CA2892003A1 (fr)
ZA (1)	ZA200501848B (fr)

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EP2277551B1 (fr)	2002-09-06	2013-05-08	Cerulean Pharma Inc.	Polymeres a base de cyclodextrine pour l'administration de medicament lies par liaison covalente
US20080176958A1 (en)	2007-01-24	2008-07-24	Insert Therapeutics, Inc.	Cyclodextrin-based polymers for therapeutics delivery
WO2009041666A1 (fr) *	2007-09-28	2009-04-02	Nanodex Inc.	Composé de cyclodextrine modifié par l'acide folique, procédé pour le produire, agent de délivrance de médicament pour le ciblage d'un système de délivrance de médicament, composition pharmaceutique et agent d'imagerie
US20120114658A1 (en) *	2009-09-15	2012-05-10	John Ryan	Treatment of cancer
EP2503888A4 (fr) *	2009-11-23	2015-07-29	Cerulean Pharma Inc	Polymères à base de cyclodextrine pour une administration thérapeutique
CN103037903A (zh) *	2010-05-18	2013-04-10	天蓝制药公司	用于治疗自身免疫性疾病或其它疾病的组合物和方法
CN102258788B (zh) *	2011-06-13	2012-11-07	南开大学	一种靶向传递阿霉素抗癌药的组装体及其制备方法
US20130196906A1 (en) *	2012-01-31	2013-08-01	Cerulean Pharma Inc.	Cyclodextrin-based polymers for therapeutic delivery
EP2826492A4 (fr) *	2012-03-13	2015-10-21	Postech Acad Ind Found	Conjugué d'administration de médicament conçu pour une libération prolongée et son utilisation
US20140094432A1 (en)	2012-10-02	2014-04-03	Cerulean Pharma Inc.	Methods and systems for polymer precipitation and generation of particles
EP2986646B1 (fr) *	2013-08-09	2019-04-10	Bio-rad Laboratories, Inc.	Détection de protéine au moyen de cyclodextrines modifiées
CN112675312B (zh) *	2020-12-30	2023-07-25	香港理工大学深圳研究院	一种脑靶向纳米递释系统及其制备方法
CN113777100B (zh) *	2021-08-27	2022-11-01	厦门大学	一种基于主客体作用的定量物质控释系统及方法
CN113855799A (zh) *	2021-10-21	2021-12-31	天津市人民医院	西达本胺联合利妥昔单抗在治疗老年复发难治性b细胞淋巴瘤疾病中的应用
CN117645698B (zh) *	2024-01-29	2024-06-04	广东工业大学	一种两亲性21臂的光敏剂-前药星型聚合物及其制备方法和应用

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US6509323B1 (en) *	1998-07-01	2003-01-21	California Institute Of Technology	Linear cyclodextrin copolymers

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- 2003-09-04 CA CA2818071A patent/CA2818071C/fr not_active Expired - Lifetime
- 2003-09-04 CN CN038248298A patent/CN1694728B/zh not_active Expired - Lifetime
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Publication number	Publication date
CA2818071C (fr)	2015-08-18
CN1694728A (zh)	2005-11-09
CA2892003A1 (fr)	2004-03-18
CN1694728B (zh)	2011-12-28
CA2818071A1 (fr)	2004-03-18

Publication	Publication Date	Title
CA2497792C (fr)	2014-08-05	Polymeres a base de cyclodextrine pour administration de medicaments
CA2818071C (fr)	2015-08-18	Composes cycliques de cyclodextrine modifies comptant exactement deux fractions hydroxyle substituees par un acide amine aux fins d'une administration de produit therapeutique
AU2012247051B2 (en)	2015-02-19	Cyclodextrin-based polymers for therapeutics delivery
HK1165305B (en)	2018-10-12	Cyclodextrin-based polymers for delivering the therapeutic agents covalently attached thereto
HK1072202B (en)	2012-07-06	Cyclodextrin-based polymers for delivering the therapeutic agents covalently bound thereto
HK1151467B (en)	2014-01-03	Cyclodextrin-based polymers for delivering the therapeutic agents covalently bound thereto
HK1165305A (en)	2012-10-05	Cyclodextrin-based polymers for delivering the therapeutic agents covalently attached thereto
AU2013204984A1 (en)	2013-05-16	Cyclodextrin-based polymers for therapeutics delivery