CA2984832C - Procedes de production du brivaracetam - Google Patents

Procedes de production du brivaracetam

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Publication number
CA2984832C
CA2984832C CA2984832A CA2984832A CA2984832C CA 2984832 C CA2984832 C CA 2984832C CA 2984832 A CA2984832 A CA 2984832A CA 2984832 A CA2984832 A CA 2984832A CA 2984832 C CA2984832 C CA 2984832C
Authority
CA
Canada
Prior art keywords
formula
compound
brivaracetam
xii
see
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CA2984832A
Other languages
English (en)
Other versions
CA2984832A1 (fr
Inventor
Peng Wang
Pixu Li
Qiang Wei
Yuanhua LIU
Original Assignee
SUZHOU PENGXU PHARMATECH Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from CN201510271449.6A external-priority patent/CN106279074B/zh
Priority claimed from CN201510430387.9A external-priority patent/CN106365986B/zh
Priority claimed from CN201510648574.4A external-priority patent/CN106432030B/zh
Application filed by SUZHOU PENGXU PHARMATECH Co Ltd filed Critical SUZHOU PENGXU PHARMATECH Co Ltd
Priority claimed from PCT/US2016/033965 external-priority patent/WO2016191435A1/fr
Publication of CA2984832A1 publication Critical patent/CA2984832A1/fr
Application granted granted Critical
Publication of CA2984832C publication Critical patent/CA2984832C/fr
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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Abstract

Il est décrit une méthode stéréosélective de fourniture d'une synthèse modifiable d'un composé de brivaracetam énantiomériquement pure de la formule XII, et de dérivés connexes de préparation de la formule XII, par dépistage de ligands ayant une affinité plus élevée de LBS que de levetiracetam, le procédé utilisant des nouveaux composés chiraux inventifs comme matière première du procédé.
CA2984832A 2015-05-25 2016-05-24 Procedes de production du brivaracetam Active CA2984832C (fr)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
CN201510271449.6 2015-05-25
CN201510271449.6A CN106279074B (zh) 2015-05-25 2015-05-25 一种化合物及其制备方法和在合成布瓦西坦中的用途
CN201510430387.9 2015-07-21
CN201510430387.9A CN106365986B (zh) 2015-07-21 2015-07-21 化合物及其制备方法和在合成布瓦西坦中的用途
CN201510648574.4 2015-10-10
CN201510648574.4A CN106432030B (zh) 2015-10-10 2015-10-10 布瓦西坦的一种制备方法
CN201610099672.1 2016-02-24
CN201610099672 2016-02-24
PCT/US2016/033965 WO2016191435A1 (fr) 2015-05-25 2016-05-24 Procédés de production du brivaracetam

Publications (2)

Publication Number Publication Date
CA2984832A1 CA2984832A1 (fr) 2016-12-01
CA2984832C true CA2984832C (fr) 2025-10-28

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