CA3008024C - Systemes de traitement d'un trouble neurologique au moyen d'un bloc de conduction nerveuse electrique - Google Patents

Systemes de traitement d'un trouble neurologique au moyen d'un bloc de conduction nerveuse electrique Download PDF

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Publication number
CA3008024C
CA3008024C CA3008024A CA3008024A CA3008024C CA 3008024 C CA3008024 C CA 3008024C CA 3008024 A CA3008024 A CA 3008024A CA 3008024 A CA3008024 A CA 3008024A CA 3008024 C CA3008024 C CA 3008024C
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Canada
Prior art keywords
encb
waveform
nerve
block
electrode
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Active
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CA3008024A
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English (en)
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CA3008024A1 (fr
Inventor
Niloy Bhadra
Narendra Bhadra
Kevin L. Kilgore
Scott LEMPKA
Jesse Wainright
Tina Vrabec
Manfred Franke
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Case Western Reserve University
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Case Western Reserve University
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Publication date
Priority claimed from US14/969,826 external-priority patent/US9694181B2/en
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Publication of CA3008024A1 publication Critical patent/CA3008024A1/fr
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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
    • A61N1/3606—Implantable neurostimulators for stimulating central or peripheral nerve system adapted for a particular treatment
    • A61N1/36071—Pain
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/05—Electrodes for implantation or insertion into the body, e.g. heart electrode
    • A61N1/0551—Spinal or peripheral nerve electrodes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/06—Electrodes for high-frequency therapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/20—Applying electric currents by contact electrodes continuous direct currents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/36014—External stimulators, e.g. with patch electrodes
    • A61N1/36021—External stimulators, e.g. with patch electrodes for treatment of pain
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
    • A61N1/36057—Implantable neurostimulators for stimulating central or peripheral nerve system adapted for stimulating afferent nerves
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
    • A61N1/3606—Implantable neurostimulators for stimulating central or peripheral nerve system adapted for a particular treatment
    • A61N1/36103—Neuro-rehabilitation; Repair or reorganisation of neural tissue, e.g. after stroke
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
    • A61N1/36125—Details of circuitry or electric components
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
    • A61N1/36128—Control systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
    • A61N1/36128—Control systems
    • A61N1/36146—Control systems specified by the stimulation parameters
    • A61N1/36167—Timing, e.g. stimulation onset
    • A61N1/36171—Frequency
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
    • A61N1/36128—Control systems
    • A61N1/36146—Control systems specified by the stimulation parameters
    • A61N1/36167—Timing, e.g. stimulation onset
    • A61N1/36175—Pulse width or duty cycle

Landscapes

  • Health & Medical Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Electrotherapy Devices (AREA)

Abstract

L'invention concerne, selon un aspect, un système comportant un générateur de formes d'onde, un dispositif de commande, et un contact électrique. Le générateur de formes d'onde est destiné à la génération d'un bloc de conduction nerveuse électrique (ENCB). Le dispositif de commande est couplé au générateur de formes d'onde. Le dispositif de commande est conçu pour recevoir une entrée comprenant au moins un paramètre pour régler l'ENCB. Le contact électrique est couplé au générateur de formes d'onde. Le contact électrique est conçu pour être placé en contact avec un nerf. Le contact électrique comprend un matériau à capacité de charge élevée qui empêche une formation de produits électrochimiques pouvant provoquer un endommagement au niveau d'une charge fournie par l'ENCB. Le contact électrique est conçu pour fournir l'ENCB au nerf pour bloquer une transmission d'un signal lié à une douleur parcourant le nerf.
CA3008024A 2015-12-15 2016-12-15 Systemes de traitement d'un trouble neurologique au moyen d'un bloc de conduction nerveuse electrique Active CA3008024C (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US14/969,826 2015-12-15
US14/969,826 US9694181B2 (en) 2012-06-15 2015-12-15 Methods of treatment of a neurological disorder using electrical nerve conduction block
PCT/US2016/066960 WO2017106519A1 (fr) 2015-12-15 2016-12-15 Systèmes de traitement d'un trouble neurologique au moyen d'un bloc de conduction nerveuse électrique

Publications (2)

Publication Number Publication Date
CA3008024A1 CA3008024A1 (fr) 2017-06-22
CA3008024C true CA3008024C (fr) 2024-04-02

Family

ID=57777701

Family Applications (1)

Application Number Title Priority Date Filing Date
CA3008024A Active CA3008024C (fr) 2015-12-15 2016-12-15 Systemes de traitement d'un trouble neurologique au moyen d'un bloc de conduction nerveuse electrique

Country Status (6)

Country Link
US (1) US20240033514A1 (fr)
EP (1) EP3389769A1 (fr)
JP (1) JP6905524B2 (fr)
AU (5) AU2016369487B2 (fr)
CA (1) CA3008024C (fr)
WO (1) WO2017106519A1 (fr)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2876297C (fr) 2012-06-15 2019-02-26 Case Western Reserve University Dispositifs d'administration de therapie et methodes pour ne pas endommager un bloc de conduction de tissu neural
US10195434B2 (en) 2012-06-15 2019-02-05 Case Western Reserve University Treatment of pain using electrical nerve conduction block
US20150238764A1 (en) 2013-05-10 2015-08-27 Case Western Reserve University Systems and methods for preventing noise in an electric waveform for neural stimulation, block, or sensing
AU2016335931B2 (en) 2015-10-06 2019-06-27 Case Western Reserve University High-charge capacity electrodes to deliver direct current nerve conduction block
US10864373B2 (en) 2015-12-15 2020-12-15 Case Western Reserve University Systems for treatment of a neurological disorder using electrical nerve conduction block
AU2018249498B2 (en) 2017-04-03 2023-12-14 Presidio Medical, Inc. Systems and methods for direct current nerve conduction block
US12465260B2 (en) 2018-02-09 2025-11-11 Presidio Medical, Inc. Systems and methods for cardiac conduction block
US11813459B2 (en) * 2018-02-20 2023-11-14 Presidio Medical, Inc. Methods and systems for nerve conduction block
US11752329B2 (en) 2018-07-01 2023-09-12 Presidio Medical, Inc. Systems and methods for nerve conduction block
AU2019325250B2 (en) * 2018-08-20 2025-03-06 Neuros Medical, Inc. Apparatuses and methods for adjusting a therapeutic electrical dose
US11318330B2 (en) * 2018-09-26 2022-05-03 General Electric Company Neuromodulation techniques
WO2021102448A1 (fr) 2019-11-24 2021-05-27 Presidio Medical, Inc. Systèmes de moteurs de stimulation et de génération d'impulsions
EP4061269A4 (fr) 2019-11-24 2023-11-08 Presidio Medical, Inc. Polarisation de courant en tant que mécanisme de commande de fonctionnement d'électrode

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7561922B2 (en) * 2004-12-22 2009-07-14 Biocontrol Medical Ltd. Construction of electrode assembly for nerve control
CA2553901C (fr) * 2004-01-22 2015-01-20 Rehabtronics Inc. Procede d'acheminement de courant electrique a des tissus corporels via des conducteurs passifs implantes
CA2703867C (fr) * 2007-10-29 2017-06-20 Case Western Reserve University Anesthesie tronculaire haute frequence d'attenuation d'attaque
WO2009111142A2 (fr) * 2008-03-06 2009-09-11 Stryker Corporation Ensemble de réseau d'électrodes implantable, pliable et outil pour implanter celui-ci
US9008800B2 (en) * 2009-11-23 2015-04-14 Case Western Reserve University Separated-interface nerve electrode
CN102821814B (zh) * 2009-12-23 2015-07-15 赛博恩特医疗器械公司 用于治疗慢性炎症的神经刺激设备和系统
EP2709717B1 (fr) * 2011-05-19 2020-02-26 Neuros Medical, Inc. Électrode à manchon et un générateur pour le blocage de nerfs électrique réversible
CA2876297C (fr) * 2012-06-15 2019-02-26 Case Western Reserve University Dispositifs d'administration de therapie et methodes pour ne pas endommager un bloc de conduction de tissu neural
EP4241832A3 (fr) * 2012-12-05 2023-11-22 Curonix LLC Dispositifs et procédés de connexion de dispositifs implantables à de l'énergie sans fil
US20140324129A1 (en) * 2013-04-30 2014-10-30 Case Western Reserve University Systems and methods for temporary, incomplete, bi-directional, adjustable electrical nerve block
WO2015142838A1 (fr) * 2014-03-18 2015-09-24 Case Western Reserve University Systèmes et procédés de blocage nerveux rapide et réversible

Also Published As

Publication number Publication date
AU2016369487A1 (en) 2018-07-12
AU2023206092B2 (en) 2025-08-07
JP2018537200A (ja) 2018-12-20
AU2021225216A1 (en) 2021-09-30
WO2017106519A1 (fr) 2017-06-22
AU2019203633A1 (en) 2019-06-13
AU2019203633B2 (en) 2021-06-17
US20240033514A1 (en) 2024-02-01
AU2021225216B2 (en) 2023-04-20
EP3389769A1 (fr) 2018-10-24
CA3008024A1 (fr) 2017-06-22
AU2025205471A1 (en) 2025-07-31
AU2016369487B2 (en) 2019-10-10
AU2023206092A1 (en) 2023-08-10
JP6905524B2 (ja) 2021-07-21

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