JP6905524B2 - 電気神経伝導ブロックを用いて神経障害を治療するシステム - Google Patents

電気神経伝導ブロックを用いて神経障害を治療するシステム Download PDF

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Publication number: JP6905524B2
Authority: JP; Japan
Prior art keywords: encb; nerve; waveform; charge; block
Prior art date: 2015-12-15
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Active

Application number

JP2018529015A

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English (en)

Japanese (ja)

Other versions

JP2018537200A (ja

Inventor

バドラ，ニロイ

バドラ，ナレンドラ

キルゴア，ケビン・エル

レンプカ，スコット

ウェーンライト，ジェシー

ヴラベッツ，ティナ

フランケ，マンフレート

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Case Western Reserve University

Original Assignee

Case Western Reserve University

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2015-12-15

Filing date

2016-12-15

Publication date

2021-07-21

2015-12-15 Priority claimed from US14/969,826 external-priority patent/US9694181B2/en

2016-12-15 Application filed by Case Western Reserve University filed Critical Case Western Reserve University

2018-12-20 Publication of JP2018537200A publication Critical patent/JP2018537200A/ja

2021-07-21 Application granted granted Critical

2021-07-21 Publication of JP6905524B2 publication Critical patent/JP6905524B2/ja

Status Active legal-status Critical Current

2036-12-15 Anticipated expiration legal-status Critical

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Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
- A61N1/3606—Implantable neurostimulators for stimulating central or peripheral nerve system adapted for a particular treatment
- A61N1/36071—Pain
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/02—Details
- A61N1/04—Electrodes
- A61N1/05—Electrodes for implantation or insertion into the body, e.g. heart electrode
- A61N1/0551—Spinal or peripheral nerve electrodes
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/02—Details
- A61N1/04—Electrodes
- A61N1/06—Electrodes for high-frequency therapy
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/20—Applying electric currents by contact electrodes continuous direct currents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/36014—External stimulators, e.g. with patch electrodes
- A61N1/36021—External stimulators, e.g. with patch electrodes for treatment of pain
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
- A61N1/36057—Implantable neurostimulators for stimulating central or peripheral nerve system adapted for stimulating afferent nerves
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
- A61N1/3606—Implantable neurostimulators for stimulating central or peripheral nerve system adapted for a particular treatment
- A61N1/36103—Neuro-rehabilitation; Repair or reorganisation of neural tissue, e.g. after stroke
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
- A61N1/36125—Details of circuitry or electric components
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
- A61N1/36128—Control systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
- A61N1/36128—Control systems
- A61N1/36146—Control systems specified by the stimulation parameters
- A61N1/36167—Timing, e.g. stimulation onset
- A61N1/36171—Frequency
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
- A61N1/36128—Control systems
- A61N1/36146—Control systems specified by the stimulation parameters
- A61N1/36167—Timing, e.g. stimulation onset
- A61N1/36175—Pulse width or duty cycle

Landscapes

Health & Medical Sciences (AREA)
Pain & Pain Management (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Engineering & Computer Science (AREA)
Biomedical Technology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Radiology & Medical Imaging (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Electrotherapy Devices (AREA)

JP2018529015A 2015-12-15 2016-12-15 電気神経伝導ブロックを用いて神経障害を治療するシステム Active JP6905524B2 (ja)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US14/969,826		2015-12-15
US14/969,826 US9694181B2 (en)	2012-06-15	2015-12-15	Methods of treatment of a neurological disorder using electrical nerve conduction block
PCT/US2016/066960 WO2017106519A1 (fr)	2015-12-15	2016-12-15	Systèmes de traitement d'un trouble neurologique au moyen d'un bloc de conduction nerveuse électrique

Publications (2)

Publication Number	Publication Date
JP2018537200A JP2018537200A (ja)	2018-12-20
JP6905524B2 true JP6905524B2 (ja)	2021-07-21

Family

ID=57777701

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
JP2018529015A Active JP6905524B2 (ja)	2015-12-15	2016-12-15	電気神経伝導ブロックを用いて神経障害を治療するシステム

Country Status (6)

Country	Link
US (1)	US20240033514A1 (fr)
EP (1)	EP3389769A1 (fr)
JP (1)	JP6905524B2 (fr)
AU (5)	AU2016369487B2 (fr)
CA (1)	CA3008024C (fr)
WO (1)	WO2017106519A1 (fr)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CA2876297C (fr)	2012-06-15	2019-02-26	Case Western Reserve University	Dispositifs d'administration de therapie et methodes pour ne pas endommager un bloc de conduction de tissu neural
US10195434B2 (en)	2012-06-15	2019-02-05	Case Western Reserve University	Treatment of pain using electrical nerve conduction block
US20150238764A1 (en)	2013-05-10	2015-08-27	Case Western Reserve University	Systems and methods for preventing noise in an electric waveform for neural stimulation, block, or sensing
AU2016335931B2 (en)	2015-10-06	2019-06-27	Case Western Reserve University	High-charge capacity electrodes to deliver direct current nerve conduction block
US10864373B2 (en)	2015-12-15	2020-12-15	Case Western Reserve University	Systems for treatment of a neurological disorder using electrical nerve conduction block
AU2018249498B2 (en)	2017-04-03	2023-12-14	Presidio Medical, Inc.	Systems and methods for direct current nerve conduction block
US12465260B2 (en)	2018-02-09	2025-11-11	Presidio Medical, Inc.	Systems and methods for cardiac conduction block
US11813459B2 (en) *	2018-02-20	2023-11-14	Presidio Medical, Inc.	Methods and systems for nerve conduction block
US11752329B2 (en)	2018-07-01	2023-09-12	Presidio Medical, Inc.	Systems and methods for nerve conduction block
AU2019325250B2 (en) *	2018-08-20	2025-03-06	Neuros Medical, Inc.	Apparatuses and methods for adjusting a therapeutic electrical dose
US11318330B2 (en) *	2018-09-26	2022-05-03	General Electric Company	Neuromodulation techniques
WO2021102448A1 (fr)	2019-11-24	2021-05-27	Presidio Medical, Inc.	Systèmes de moteurs de stimulation et de génération d'impulsions
EP4061269A4 (fr)	2019-11-24	2023-11-08	Presidio Medical, Inc.	Polarisation de courant en tant que mécanisme de commande de fonctionnement d'électrode

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US7561922B2 (en) *	2004-12-22	2009-07-14	Biocontrol Medical Ltd.	Construction of electrode assembly for nerve control
CA2553901C (fr) *	2004-01-22	2015-01-20	Rehabtronics Inc.	Procede d'acheminement de courant electrique a des tissus corporels via des conducteurs passifs implantes
CA2703867C (fr) *	2007-10-29	2017-06-20	Case Western Reserve University	Anesthesie tronculaire haute frequence d'attenuation d'attaque
WO2009111142A2 (fr) *	2008-03-06	2009-09-11	Stryker Corporation	Ensemble de réseau d'électrodes implantable, pliable et outil pour implanter celui-ci
US9008800B2 (en) *	2009-11-23	2015-04-14	Case Western Reserve University	Separated-interface nerve electrode
CN102821814B (zh) *	2009-12-23	2015-07-15	赛博恩特医疗器械公司	用于治疗慢性炎症的神经刺激设备和系统
EP2709717B1 (fr) *	2011-05-19	2020-02-26	Neuros Medical, Inc.	Électrode à manchon et un générateur pour le blocage de nerfs électrique réversible
CA2876297C (fr) *	2012-06-15	2019-02-26	Case Western Reserve University	Dispositifs d'administration de therapie et methodes pour ne pas endommager un bloc de conduction de tissu neural
EP4241832A3 (fr) *	2012-12-05	2023-11-22	Curonix LLC	Dispositifs et procédés de connexion de dispositifs implantables à de l'énergie sans fil
US20140324129A1 (en) *	2013-04-30	2014-10-30	Case Western Reserve University	Systems and methods for temporary, incomplete, bi-directional, adjustable electrical nerve block
WO2015142838A1 (fr) *	2014-03-18	2015-09-24	Case Western Reserve University	Systèmes et procédés de blocage nerveux rapide et réversible

2016
- 2016-12-15 CA CA3008024A patent/CA3008024C/fr active Active
- 2016-12-15 JP JP2018529015A patent/JP6905524B2/ja active Active
- 2016-12-15 AU AU2016369487A patent/AU2016369487B2/en active Active
- 2016-12-15 WO PCT/US2016/066960 patent/WO2017106519A1/fr not_active Ceased
- 2016-12-15 EP EP16825621.2A patent/EP3389769A1/fr not_active Withdrawn
2019
- 2019-05-23 AU AU2019203633A patent/AU2019203633B2/en active Active
2021
- 2021-09-02 AU AU2021225216A patent/AU2021225216B2/en active Active
2023
- 2023-07-18 AU AU2023206092A patent/AU2023206092B2/en active Active
- 2023-10-09 US US18/482,926 patent/US20240033514A1/en active Pending
2025
- 2025-07-15 AU AU2025205471A patent/AU2025205471A1/en active Pending

Also Published As

Publication number	Publication date
AU2016369487A1 (en)	2018-07-12
AU2023206092B2 (en)	2025-08-07
JP2018537200A (ja)	2018-12-20
AU2021225216A1 (en)	2021-09-30
WO2017106519A1 (fr)	2017-06-22
AU2019203633A1 (en)	2019-06-13
AU2019203633B2 (en)	2021-06-17
US20240033514A1 (en)	2024-02-01
AU2021225216B2 (en)	2023-04-20
EP3389769A1 (fr)	2018-10-24
CA3008024A1 (fr)	2017-06-22
AU2025205471A1 (en)	2025-07-31
AU2016369487B2 (en)	2019-10-10
AU2023206092A1 (en)	2023-08-10
CA3008024C (fr)	2024-04-02

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Date	Code	Title	Description
2019-11-19	A621	Written request for application examination	Free format text: JAPANESE INTERMEDIATE CODE: A621 Effective date: 20191119
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2021-06-11	A01	Written decision to grant a patent or to grant a registration (utility model)	Free format text: JAPANESE INTERMEDIATE CODE: A01 Effective date: 20210611
2021-06-29	A61	First payment of annual fees (during grant procedure)	Free format text: JAPANESE INTERMEDIATE CODE: A61 Effective date: 20210625
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Publication	Publication Date	Title
US11779762B2 (en)	2023-10-10	Systems for treatment of a neurological disorder using electrical nerve conduction block
JP6905524B2 (ja)	2021-07-21	電気神経伝導ブロックを用いて神経障害を治療するシステム
US11872394B2 (en)	2024-01-16	Treatment of pain using electrical nerve conduction block
US9694181B2 (en)	2017-07-04	Methods of treatment of a neurological disorder using electrical nerve conduction block
US12161861B2 (en)	2024-12-10	Therapy delivery devices and methods for non-damaging neural tissue conduction block