CA3204457A1 - Mdma dans le traitement d'un trouble de consommation d'alcool - Google Patents

Mdma dans le traitement d'un trouble de consommation d'alcool Download PDF

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Publication number
CA3204457A1
CA3204457A1 CA3204457A CA3204457A CA3204457A1 CA 3204457 A1 CA3204457 A1 CA 3204457A1 CA 3204457 A CA3204457 A CA 3204457A CA 3204457 A CA3204457 A CA 3204457A CA 3204457 A1 CA3204457 A1 CA 3204457A1
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CA
Canada
Prior art keywords
mdma
subject
psychotherapy
alcohol
assisted
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CA3204457A
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English (en)
Inventor
Ben SESSA
Laurie HIGBED
David Nutt
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Awakn Ls Europe Holdings Ltd
Original Assignee
Awakn Ls Europe Holdings Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Awakn Ls Europe Holdings Ltd filed Critical Awakn Ls Europe Holdings Ltd
Publication of CA3204457A1 publication Critical patent/CA3204457A1/fr
Pending legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/357—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having two or more oxygen atoms in the same ring, e.g. crown ethers, guanadrel
    • A61K31/36—Compounds containing methylenedioxyphenyl groups, e.g. sesamin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/32—Alcohol-abuse

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  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Addiction (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Psychiatry (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

L'invention divulgue des compositions de MDMA et des procédés d'utilisation de celles-ci dans la psychothérapie assistée par MDMA pour le traitement de patients atteints d'un trouble de consommation d'alcool (AUD) comprenant un trouble de consommation d'alcool dépendant physiquement («?consommation dépendante?» ou «?dépendance à l'alcool?») et un trouble de consommation d'alcool non dépendant physiquement («?consommation nocive?»).
CA3204457A 2021-01-06 2022-01-06 Mdma dans le traitement d'un trouble de consommation d'alcool Pending CA3204457A1 (fr)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US202163134582P 2021-01-06 2021-01-06
US63/134,582 2021-01-06
US202163137615P 2021-01-14 2021-01-14
US63/137,615 2021-01-14
PCT/US2022/011511 WO2022150525A1 (fr) 2021-01-06 2022-01-06 Mdma dans le traitement d'un trouble de consommation d'alcool

Publications (1)

Publication Number Publication Date
CA3204457A1 true CA3204457A1 (fr) 2022-07-14

Family

ID=80050571

Family Applications (1)

Application Number Title Priority Date Filing Date
CA3204457A Pending CA3204457A1 (fr) 2021-01-06 2022-01-06 Mdma dans le traitement d'un trouble de consommation d'alcool

Country Status (2)

Country Link
CA (1) CA3204457A1 (fr)
WO (1) WO2022150525A1 (fr)

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CA3221280A1 (fr) 2021-06-03 2022-12-08 Arcadia Medicine, Inc. Compositions entactogenes enantiomeres et leurs methodes d'utilisation
EP4387612A4 (fr) 2021-08-20 2025-07-23 Pharmala Biotech Inc Compositions comprenant des mélanges non racémiques de (r)-et (s)-3,4-méthylènedioxyméthamphétamine ou (r) et (s) n-méthyl -1,3-benzodioxolylbutanamine et leurs utilisations
US12492178B2 (en) 2021-09-01 2025-12-09 Empathbio, Inc. Stable polymorph of R-MDMA HCl
WO2023034510A1 (fr) 2021-09-01 2023-03-09 ATAI Life Sciences AG Synthèse de mdma ou de ses isomères optiquement actifs (r)- ou (s)-mdma
US11845736B2 (en) 2021-10-01 2023-12-19 Empathbio, Inc. Prodrugs of MDMA, MDA, and derivatives thereof
US20240423950A1 (en) * 2021-10-07 2024-12-26 Clearmind Medicine Inc. 5-mapb or 6-apb for use in drug-assisted psychotherapy
US11912680B2 (en) 2021-12-28 2024-02-27 Empathbio, Inc. Nitric oxide releasing prodrugs of MDA and MDMA
CA3242786A1 (fr) * 2022-01-07 2023-07-13 Universitatsspital Basel R-mdma et s-mdma pour aider la psychotherapie
JP2025530256A (ja) * 2022-09-09 2025-09-11 エーティーエーアイ ライフ サインエンシズ エージー ストレス関連障害の治療のためのｍｄｍａの使用
WO2024064825A1 (fr) * 2022-09-21 2024-03-28 Axsome Therapeutics, Inc. Composés et combinaisons de ceux-ci pour le traitement d'états neurologiques et psychiatriques
JP2025539064A (ja) * 2022-11-11 2025-12-03 ギルガメッシュ・ファーマシューティカルズ・インコーポレイテッド トラゾドンを使用して５－ｈｔ２ａ受容体アゴニストの効果を逆転させる方法
EP4611738A1 (fr) * 2022-12-05 2025-09-10 Lykos Therapeutics, Inc. Compositions comprenant de la mdma et leurs méthodes d'utilisation
WO2024178082A2 (fr) * 2023-02-22 2024-08-29 Freedom Biosciences, Inc. Composition de modulateur des récepteurs opioïdes et mdma pour son utilisation
EP4673125A1 (fr) * 2023-02-28 2026-01-07 Mind Medicine, Inc. R-mdma pour le traitement de la douleur
WO2024196772A2 (fr) * 2023-03-20 2024-09-26 Mind Medicine, Inc. Énantiomères de mdma
AU2024405896A1 (en) * 2023-12-22 2026-05-14 Empathbio, Inc. R(-)-mdma compositions and methods of treatment
WO2025160483A1 (fr) * 2024-01-24 2025-07-31 Awakn Ls Europe Holdings Limited Thérapie orale transmucosale d'eskétamine pour trouble lié à la consommation d'alcool et troubles lié à la consommation de substances

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Also Published As

Publication number Publication date
WO2022150525A9 (fr) 2023-04-20
WO2022150525A1 (fr) 2022-07-14

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