CA3250706A1 - TREATMENT OF NEUROLOGICAL DISORDERS - Google Patents
TREATMENT OF NEUROLOGICAL DISORDERSInfo
- Publication number
- CA3250706A1 CA3250706A1 CA3250706A CA3250706A CA3250706A1 CA 3250706 A1 CA3250706 A1 CA 3250706A1 CA 3250706 A CA3250706 A CA 3250706A CA 3250706 A CA3250706 A CA 3250706A CA 3250706 A1 CA3250706 A1 CA 3250706A1
- Authority
- CA
- Canada
- Prior art keywords
- compound
- epilepsy
- pharmaceutically acceptable
- acceptable salt
- formula
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/4985—Pyrazines or piperazines ortho- or peri-condensed with heterocyclic ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
Landscapes
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Neurosurgery (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202263335204P | 2022-04-26 | 2022-04-26 | |
| US63/335,204 | 2022-04-26 | ||
| US202263349402P | 2022-06-06 | 2022-06-06 | |
| US63/349,402 | 2022-06-06 | ||
| US202263357944P | 2022-07-01 | 2022-07-01 | |
| US63/357,944 | 2022-07-01 | ||
| PCT/US2023/019652 WO2023211852A1 (en) | 2022-04-26 | 2023-04-24 | Treatment of neurological disorders |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA3250706A1 true CA3250706A1 (en) | 2023-11-02 |
Family
ID=88519529
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA3250706A Pending CA3250706A1 (en) | 2022-04-26 | 2023-04-24 | TREATMENT OF NEUROLOGICAL DISORDERS |
Country Status (12)
| Country | Link |
|---|---|
| US (2) | US20250312338A1 (de) |
| EP (1) | EP4514347A4 (de) |
| JP (1) | JP2025515501A (de) |
| KR (1) | KR20250005348A (de) |
| CN (1) | CN119522099A (de) |
| AU (1) | AU2023260468A1 (de) |
| CA (1) | CA3250706A1 (de) |
| CL (1) | CL2024003261A1 (de) |
| CO (1) | CO2024015551A2 (de) |
| IL (1) | IL316541A (de) |
| MX (1) | MX2024013240A (de) |
| WO (1) | WO2023211852A1 (de) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114980899A (zh) * | 2019-11-26 | 2022-08-30 | 普拉西斯精密医药公司 | 离子通道调节剂 |
| PE20221280A1 (es) * | 2019-11-27 | 2022-09-05 | Praxis Prec Medicines Inc | Formulaciones de moduladores de canales ionicos y metodos de preparacion y uso de moduladores de canales ionicos |
| WO2025259553A1 (en) * | 2024-06-09 | 2025-12-18 | Praxis Precision Medicines, Inc. | Methods of treatment of neurological disorders |
| CN121550436A (zh) * | 2026-01-23 | 2026-02-24 | 四川大学华西医院 | 新靶点在结节性硬化症相关癫痫中的应用、组合物及联合用药方式 |
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| US4112095A (en) | 1976-10-07 | 1978-09-05 | American Cyanamid Company | 6-Phenyl-1,2,4-triazolo[4,3-b]pyridazine hypotensive agents |
| US4242515A (en) | 1979-03-28 | 1980-12-30 | American Cyanamid Company | Substituted 3-alkyl-6-phenyl-1,2,4-triazolo-[4,3-a]pyridines |
| US4326525A (en) | 1980-10-14 | 1982-04-27 | Alza Corporation | Osmotic device that improves delivery properties of agent in situ |
| US5364620A (en) | 1983-12-22 | 1994-11-15 | Elan Corporation, Plc | Controlled absorption diltiazem formulation for once daily administration |
| US5023252A (en) | 1985-12-04 | 1991-06-11 | Conrex Pharmaceutical Corporation | Transdermal and trans-membrane delivery of drugs |
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| WO2002006286A2 (en) | 2000-07-14 | 2002-01-24 | Bristol-Myers Squibb Pharma Company | IMIDAZO[1,2-a]PYRAZINES FOR THE TREATMENT OF NEUROLOGICAL DISORDERS |
| WO2006061428A2 (en) | 2004-12-10 | 2006-06-15 | Universität Zürich | Gaba-a alpha 2 and alpha 3 receptor agonists for treating neuropathic, inflammatory and migraine associated pain |
| EP1904630A4 (de) | 2005-06-16 | 2009-10-21 | Bionomics Ltd | Verfahren zur behandlung und diagnose von epilepsie durch nachweisen von mutationen im scn1a-gen |
| KR100669497B1 (ko) | 2005-08-17 | 2007-01-16 | 보람제약주식회사 | 안정성과 용출률이 뛰어난 약리학적 조성물 및 그 제조방법 |
| HRP20170103T1 (hr) | 2005-12-21 | 2017-03-24 | Janssen Pharmaceutica N.V. | Triazolopiridazini kao modulatori tirozin kinaze |
| US8217177B2 (en) | 2006-07-14 | 2012-07-10 | Amgen Inc. | Fused heterocyclic derivatives and methods of use |
| PE20080403A1 (es) | 2006-07-14 | 2008-04-25 | Amgen Inc | Derivados heterociclicos fusionados y metodos de uso |
| US8198448B2 (en) | 2006-07-14 | 2012-06-12 | Amgen Inc. | Fused heterocyclic derivatives and methods of use |
| KR100858357B1 (ko) | 2006-10-02 | 2008-09-11 | (주) 디지탈바이오텍 | 벤조퓨란계 유도체 화합물을 유효성분으로 함유하는인지기능 장애의 예방 및 치료용 조성물 |
| FR2915198B1 (fr) | 2007-04-18 | 2009-12-18 | Sanofi Aventis | Derives de triazolopyridine-carboxamides et triazolopyridine -carboxamides, leur preparation et leur application en therapeutique. |
| CA2713521A1 (en) | 2008-02-06 | 2009-08-13 | Gilead Palo Alto, Inc. | Use of ranolazine for treating pain |
| WO2010053757A1 (en) | 2008-10-29 | 2010-05-14 | Gilead Palo Alto, Inc. | 2 -oxoquinoxalin blockers of the late sodium channel |
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| CN102439008B (zh) | 2009-05-12 | 2015-04-29 | 杨森制药有限公司 | 1,2,4-三唑并[4,3-a]吡啶衍生物及其用于治疗或预防神经和精神病症的用途 |
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| FR2953520B1 (fr) | 2009-12-04 | 2011-11-25 | Sanofi Aventis | Derives de diphenyl-pyrazolopyridines, leur preparation et leur application en therapeutique |
| US20130315895A1 (en) | 2010-07-01 | 2013-11-28 | Takeda Pharmaceutical Company Limited | COMBINATION OF A cMET INHIBITOR AND AN ANTIBODY TO HGF AND/OR cMET |
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| WO2012065297A1 (en) | 2010-11-16 | 2012-05-24 | Impact Therapeutics, Inc. | 3-ARYL-6-ARYL-[1,2,4]TRIAZOLO[4,3-a]PYRIDINES AS INHIBITORS OF CELL PROLIFERATION AND THE USE THEREOF |
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| KR20140033377A (ko) | 2011-05-10 | 2014-03-18 | 길리애드 사이언시즈, 인코포레이티드 | 나트륨 채널 조절제로서의 융합된 헤테로시클릭 화합물 |
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| AU2015279377B2 (en) | 2014-06-26 | 2019-09-12 | F. Hoffmann-La Roche Ag | Indolin-2-one or pyrrolo-pyridin-2-one derivatives |
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| CN114980899A (zh) | 2019-11-26 | 2022-08-30 | 普拉西斯精密医药公司 | 离子通道调节剂 |
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| PE20221280A1 (es) | 2019-11-27 | 2022-09-05 | Praxis Prec Medicines Inc | Formulaciones de moduladores de canales ionicos y metodos de preparacion y uso de moduladores de canales ionicos |
-
2023
- 2023-04-24 KR KR1020247038722A patent/KR20250005348A/ko active Pending
- 2023-04-24 US US18/860,376 patent/US20250312338A1/en active Pending
- 2023-04-24 EP EP23797093.4A patent/EP4514347A4/de active Pending
- 2023-04-24 WO PCT/US2023/019652 patent/WO2023211852A1/en not_active Ceased
- 2023-04-24 JP JP2024563668A patent/JP2025515501A/ja active Pending
- 2023-04-24 CA CA3250706A patent/CA3250706A1/en active Pending
- 2023-04-24 CN CN202380049639.6A patent/CN119522099A/zh active Pending
- 2023-04-24 AU AU2023260468A patent/AU2023260468A1/en active Pending
- 2023-04-24 MX MX2024013240A patent/MX2024013240A/es unknown
- 2023-04-24 IL IL316541A patent/IL316541A/en unknown
-
2024
- 2024-10-25 US US18/927,377 patent/US12582652B2/en active Active
- 2024-10-25 CL CL2024003261A patent/CL2024003261A1/es unknown
- 2024-11-15 CO CONC2024/0015551A patent/CO2024015551A2/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| US12582652B2 (en) | 2026-03-24 |
| EP4514347A1 (de) | 2025-03-05 |
| WO2023211852A1 (en) | 2023-11-02 |
| CO2024015551A2 (es) | 2024-11-28 |
| US20250312338A1 (en) | 2025-10-09 |
| AU2023260468A1 (en) | 2024-11-28 |
| CL2024003261A1 (es) | 2025-05-16 |
| KR20250005348A (ko) | 2025-01-09 |
| MX2024013240A (es) | 2024-12-06 |
| IL316541A (en) | 2024-12-01 |
| EP4514347A4 (de) | 2026-04-22 |
| CN119522099A (zh) | 2025-02-25 |
| US20250049790A1 (en) | 2025-02-13 |
| JP2025515501A (ja) | 2025-05-15 |
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Legal Events
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