CA977754A - 2-(3',4',5'-trisubstituted-benzyl) pyrimidine compounds - Google Patents

2-(3',4',5'-trisubstituted-benzyl) pyrimidine compounds

Info

Publication number
CA977754A
CA977754A CA983,015A CA983015A CA977754A CA 977754 A CA977754 A CA 977754A CA 983015 A CA983015 A CA 983015A CA 977754 A CA977754 A CA 977754A
Authority
CA
Canada
Prior art keywords
trisubstituted
benzyl
pyrimidine compounds
pyrimidine
compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA983,015A
Other languages
English (en)
Inventor
Barbara Roth
Justina Strelitz
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wellcome Foundation Ltd
Original Assignee
Wellcome Foundation Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wellcome Foundation Ltd filed Critical Wellcome Foundation Ltd
Application granted granted Critical
Publication of CA977754A publication Critical patent/CA977754A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/47—One nitrogen atom and one oxygen or sulfur atom, e.g. cytosine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/48—Two nitrogen atoms
    • C07D239/49—Two nitrogen atoms with an aralkyl radical, or substituted aralkyl radical, attached in position 5, e.g. trimethoprim
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/50—Three nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/52—Two oxygen atoms
    • C07D239/54—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Lubricants (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Liquid Crystal Substances (AREA)
CA983,015A 1966-02-19 1967-02-15 2-(3',4',5'-trisubstituted-benzyl) pyrimidine compounds Expired CA977754A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB737666A GB1128234A (en) 1966-02-19 1966-02-19 5-benzylpyrimidine derivatives and process for the preparation thereof

Publications (1)

Publication Number Publication Date
CA977754A true CA977754A (en) 1975-11-11

Family

ID=9831956

Family Applications (1)

Application Number Title Priority Date Filing Date
CA983,015A Expired CA977754A (en) 1966-02-19 1967-02-15 2-(3',4',5'-trisubstituted-benzyl) pyrimidine compounds

Country Status (16)

Country Link
AT (2) AT270653B (da)
BE (1) BE694244A (da)
CA (1) CA977754A (da)
CH (2) CH511239A (da)
DE (2) DE1795635C3 (da)
DK (2) DK120344B (da)
ES (1) ES336945A1 (da)
FI (1) FI49714C (da)
FR (1) FR6595M (da)
GB (1) GB1128234A (da)
GR (1) GR33641B (da)
IL (1) IL27424A (da)
MY (1) MY7100226A (da)
NL (1) NL146811B (da)
NO (1) NO124601B (da)
SE (2) SE338998B (da)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE789904A (fr) * 1971-10-12 1973-04-10 Wellcome Found Procedes de synthese organique
MC1264A1 (fr) * 1978-05-24 1980-03-28 Wellcome Found Procede de preparation de benzylpyrimides et de medicaments contenant ces substances
DE2944145A1 (de) 1979-11-02 1981-05-14 Dynamit Nobel Ag, 5210 Troisdorf Verfahren zur herstellung von 2,4-diaminopyrimidin

Also Published As

Publication number Publication date
NO124601B (da) 1972-05-08
SE390412B (sv) 1976-12-20
MY7100226A (en) 1971-12-31
CH513179A (de) 1971-09-30
FI49714C (fi) 1975-09-10
ES336945A1 (es) 1968-01-16
GB1128234A (en) 1968-09-25
AT275534B (de) 1969-10-27
BE694244A (da) 1967-08-17
AT270653B (de) 1969-05-12
DE1795635C3 (de) 1978-05-11
IL27424A (en) 1971-02-25
DK128247B (da) 1974-03-25
DE1720012B2 (de) 1977-06-08
FI49714B (da) 1975-06-02
CH511239A (de) 1971-08-15
DE1795635A1 (de) 1972-10-19
DE1720012A1 (de) 1972-04-06
SE338998B (da) 1971-09-27
DK120344B (da) 1971-05-17
FR6595M (da) 1969-01-06
DE1795635B2 (de) 1977-09-22
NL146811B (nl) 1975-08-15
GR33641B (el) 1968-01-03
NL6702397A (da) 1967-08-21

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