CA978945A - Process for preparing 2 and 3 substituted-4-heterocyclic amino-sulfonyl benzene sulfonamides as cerebral vasodilators - Google Patents

Process for preparing 2 and 3 substituted-4-heterocyclic amino-sulfonyl benzene sulfonamides as cerebral vasodilators

Info

Publication number
CA978945A
CA978945A CA178,508A CA178508A CA978945A CA 978945 A CA978945 A CA 978945A CA 178508 A CA178508 A CA 178508A CA 978945 A CA978945 A CA 978945A
Authority
CA
Canada
Prior art keywords
substituted
preparing
heterocyclic amino
cerebral vasodilators
benzene sulfonamides
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA178,508A
Other languages
English (en)
Other versions
CA178508S (en
Inventor
Brian Gadsby
Peter E. Cross
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Corp SRL
Original Assignee
Pfizer Corp SRL
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Corp SRL filed Critical Pfizer Corp SRL
Application granted granted Critical
Publication of CA978945A publication Critical patent/CA978945A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/22—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with hetero atoms directly attached to ring nitrogen atoms
    • C07D295/26—Sulfur atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/40—Oxygen atoms
    • C07D211/44—Oxygen atoms attached in position 4
    • C07D211/46—Oxygen atoms attached in position 4 having a hydrogen atom as the second substituent in position 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/92—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with a hetero atom directly attached to the ring nitrogen atom
    • C07D211/96—Sulfur atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D265/28—1,4-Oxazines; Hydrogenated 1,4-oxazines
    • C07D265/34—1,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings
    • C07D265/36—1,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings condensed with one six-membered ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D267/00—Heterocyclic compounds containing rings of more than six members having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D267/02—Seven-membered rings
    • C07D267/08—Seven-membered rings having the hetero atoms in positions 1 and 4
    • C07D267/10—Seven-membered rings having the hetero atoms in positions 1 and 4 not condensed with other rings
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09B—ORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
    • C09B31/00—Disazo and polyazo dyes of the type A->B->C, A->B->C->D, or the like, prepared by diazotising and coupling
    • C09B31/02—Disazo dyes
    • C09B31/12—Disazo dyes from other coupling components "C"
    • C09B31/14—Heterocyclic components

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Cardiology (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pyrrole Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
CA178,508A 1972-08-12 1973-08-10 Process for preparing 2 and 3 substituted-4-heterocyclic amino-sulfonyl benzene sulfonamides as cerebral vasodilators Expired CA978945A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB3772072A GB1380009A (en) 1972-08-12 1972-08-12 Cyclic derivatives of 1,4-benzene disulphonamide

Publications (1)

Publication Number Publication Date
CA978945A true CA978945A (en) 1975-12-02

Family

ID=10398552

Family Applications (1)

Application Number Title Priority Date Filing Date
CA178,508A Expired CA978945A (en) 1972-08-12 1973-08-10 Process for preparing 2 and 3 substituted-4-heterocyclic amino-sulfonyl benzene sulfonamides as cerebral vasodilators

Country Status (16)

Country Link
US (1) US3867390A (de)
JP (2) JPS59508B2 (de)
AT (1) AT331248B (de)
AU (1) AU5908473A (de)
BE (1) BE803373A (de)
CA (1) CA978945A (de)
DE (1) DE2340010A1 (de)
ES (1) ES417806A1 (de)
FR (1) FR2195449B1 (de)
GB (1) GB1380009A (de)
IE (1) IE38177B1 (de)
IN (1) IN139006B (de)
LU (1) LU68211A1 (de)
NL (1) NL162641C (de)
SE (1) SE385008B (de)
ZA (1) ZA735474B (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4070361A (en) * 1977-04-21 1978-01-24 E. R. Squibb & Sons, Inc. Mercaptoalkylsulfonyl proline and pipecolic acid and esters thereof
DE2720654A1 (de) * 1977-05-07 1978-11-16 Bayer Ag Azolyl-alkancarbonsaeure-derivate, verfahren zu ihrer herstellung und ihre verwendung als fungizide
GB1572226A (en) * 1977-11-03 1980-07-30 Hoechst Uk Ltd Pharmaceutical preparations in solid unit dosage form
JPS5922023A (ja) * 1982-07-27 1984-02-04 Hoya Corp ビ−ムスプリツタ−

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3165550A (en) * 1960-06-29 1965-01-12 Pfizer & Co C N-substituted p-benzenedisulfonamides

Also Published As

Publication number Publication date
FR2195449A1 (de) 1974-03-08
LU68211A1 (de) 1975-05-21
DE2340010A1 (de) 1974-03-14
IN139006B (de) 1976-04-24
SE385008B (sv) 1976-05-31
ES417806A1 (es) 1976-03-01
NL162641C (nl) 1980-06-16
JPS4985066A (de) 1974-08-15
JPS5857431B2 (ja) 1983-12-20
BE803373A (fr) 1974-02-08
AU5908473A (en) 1975-02-13
NL162641B (nl) 1980-01-15
IE38177B1 (en) 1978-01-18
GB1380009A (en) 1975-01-08
JPS59508B2 (ja) 1984-01-07
ATA691573A (de) 1975-11-15
ZA735474B (en) 1974-08-28
US3867390A (en) 1975-02-18
FR2195449B1 (de) 1977-09-09
IE38177L (en) 1974-02-12
AT331248B (de) 1976-08-10
JPS57131774A (en) 1982-08-14
NL7311000A (de) 1974-02-14

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