CH103776A - A method of manufacturing oxyethylarsinic acid. - Google Patents
A method of manufacturing oxyethylarsinic acid.Info
- Publication number
- CH103776A CH103776A CH103776DA CH103776A CH 103776 A CH103776 A CH 103776A CH 103776D A CH103776D A CH 103776DA CH 103776 A CH103776 A CH 103776A
- Authority
- CH
- Switzerland
- Prior art keywords
- acid
- oxyethylarsinic
- manufacturing
- glycol
- manufacture
- Prior art date
Links
- 239000002253 acid Substances 0.000 title claims description 6
- 238000004519 manufacturing process Methods 0.000 title claims description 4
- LYCAIKOWRPUZTN-UHFFFAOYSA-N Ethylene glycol Chemical compound OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 claims description 6
- 238000000034 method Methods 0.000 claims description 5
- WGCNASOHLSPBMP-UHFFFAOYSA-N hydroxyacetaldehyde Natural products OCC=O WGCNASOHLSPBMP-UHFFFAOYSA-N 0.000 claims description 3
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 3
- AQLMHYSWFMLWBS-UHFFFAOYSA-N arsenite(1-) Chemical compound O[As](O)[O-] AQLMHYSWFMLWBS-UHFFFAOYSA-N 0.000 claims description 2
- 229940079593 drug Drugs 0.000 claims description 2
- 239000003814 drug Substances 0.000 claims description 2
- 230000001256 tonic effect Effects 0.000 claims description 2
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 2
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 description 2
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 2
- QAOWNCQODCNURD-UHFFFAOYSA-N Sulfuric acid Chemical compound OS(O)(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-N 0.000 description 2
- SSZWWUDQMAHNAQ-UHFFFAOYSA-N 3-chloropropane-1,2-diol Chemical compound OCC(O)CCl SSZWWUDQMAHNAQ-UHFFFAOYSA-N 0.000 description 1
- GOLCXWYRSKYTSP-UHFFFAOYSA-N Arsenious Acid Chemical compound O1[As]2O[As]1O2 GOLCXWYRSKYTSP-UHFFFAOYSA-N 0.000 description 1
- CDBYLPFSWZWCQE-UHFFFAOYSA-L Sodium Carbonate Chemical compound [Na+].[Na+].[O-]C([O-])=O CDBYLPFSWZWCQE-UHFFFAOYSA-L 0.000 description 1
- VJWWIRSVNSXUAC-UHFFFAOYSA-N arsinic acid Chemical compound O[AsH2]=O VJWWIRSVNSXUAC-UHFFFAOYSA-N 0.000 description 1
- 159000000009 barium salts Chemical class 0.000 description 1
- 230000008020 evaporation Effects 0.000 description 1
- 238000001704 evaporation Methods 0.000 description 1
- 239000011780 sodium chloride Substances 0.000 description 1
- 238000003756 stirring Methods 0.000 description 1
Landscapes
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Description
Procédé de fabrication de Facide ogyéthylarsinique. La présente invention se rapporte à un procédé de fabrication de l'acide oxyéthyl- arsinique. Ce procédé est caractérisé en ce que l'on fait agir un arsénite alcalin sur une monohalogènehydrine du glycol.
Ce procédé peut être mis en oeuvre par exemple de la façon suivante: 80 grammes .de la monochlorhydrine du glycol sont ajoutés à une solution de 100 grammes d'acide arsénieux dans 300, cc. de soude à 33%. La réaction se fait sous agi- tation en une demi-heure.
On acidifie par l'acide chlorhydrique; on élimine la plus grande partie du chlorure de sodium par l'alcool; on reprend le résidu après évapora tion de l'alcool par l'eau et on isole l'acide sous forme de sel de baryum; celui-ci étant décomposé par l'acide sulfurique étendu et la solution évaporée à sec. L'acide libre est un produit incolore, très soluble dans l'eau et qui présente la formule OH.CH2.CH2.ASOIH Il s'emploiera avec avantage comme médica ment tonique.
Process for the manufacture of ogyethylarsinic acid. The present invention relates to a process for the manufacture of oxyethyl arsinic acid. This process is characterized in that an alkaline arsenite is made to act on a monohalogenhydrin of the glycol.
This process can be carried out, for example, as follows: 80 grams of the monochlorohydrin of the glycol are added to a solution of 100 grams of arsenious acid in 300 cc. 33% soda. The reaction takes place with stirring in half an hour.
Acidified with hydrochloric acid; most of the sodium chloride is removed by alcohol; the residue is taken up after evaporation of the alcohol with water and the acid is isolated in the form of the barium salt; the latter being decomposed by extended sulfuric acid and the solution evaporated to dryness. The free acid is a colorless product, very soluble in water and which has the formula OH.CH2.CH2.ASOIH It will be used with advantage as a tonic drug.
Claims (1)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR103776X | 1921-12-29 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CH103776A true CH103776A (en) | 1924-03-01 |
Family
ID=8871939
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CH103776D CH103776A (en) | 1921-12-29 | 1922-10-28 | A method of manufacturing oxyethylarsinic acid. |
Country Status (1)
| Country | Link |
|---|---|
| CH (1) | CH103776A (en) |
-
1922
- 1922-10-28 CH CH103776D patent/CH103776A/en unknown
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US2151517A (en) | Preparation of arylnitroalkanols | |
| US2343547A (en) | Organo-mercury compound | |
| US1693432A (en) | Therapeutically-active aromatic compound containing mercury in a lateral chain and process of making the same | |
| US1444802A (en) | Ernst prejswerk | |
| US2557772A (en) | N-[2-methoxy-3-(1, 2-dicarboxyethylthiomercuri)-propyl]-phthalamide | |
| CH104208A (en) | Manufacturing process of monooxypropyl-1-3-diarsinic acid. | |
| US2305734A (en) | Calcium hydroxy formate and process of production | |
| US2073997A (en) | Alkyl alpha-naphthols | |
| SU456521A1 (en) | Method of preparing 5-amino-benzodioxane-1,4 | |
| SU14932A1 (en) | The method of obtaining chlorine-substituted 4.4-dioxy-5.5-bisacylamino-1.1-arsenobenzenes | |
| US2339787A (en) | Substituted para-aminobenzene sulphonamide compound | |
| CH299940A (en) | Process for the preparation of a pyrimidine derivative. | |
| CH104790A (en) | Process for preparing a derivative of naphthoquinone. | |
| CH104486A (en) | Process for manufacturing a new complex arseno-antimonial compound. | |
| US1942800A (en) | Sodium para-phenylphenate and method of making same | |
| CH104209A (en) | Process for the preparation of a 4.4'-dioxy-3.3'-diaminoarsenobenzene compound. | |
| CH236176A (en) | Process for the preparation of p-aminobenzenesulfonyl-allyl-thiourea. | |
| CH236175A (en) | Process for the preparation of p-aminobenzenesulfonyl-methyl-thiourea. | |
| CH297992A (en) | Process for the preparation of a pyrimidine derivative. | |
| CH209332A (en) | Process for the manufacture of 8-bromine-1-naphthoic acid. | |
| CH243935A (en) | Process for the manufacture of calcium mono-methyl formate. | |
| CH200185A (en) | Process for preparing the alpha-phenyl-n-valerate of diethylaminoethanol. | |
| CH299943A (en) | Process for the preparation of a pyrimidine derivative. | |
| CH309341A (en) | A process for preparing 5,5'-bis (trimethylammonium) -dipentylether dichloride. | |
| CH199089A (en) | Process for obtaining a thiazol compound. |