CH376505A - Verfahren zur Herstellung von basischen Phenothiazin-Derivaten, die in 3-Stellung mit einer einwertigen Schwefelfunktion substituiert sind - Google Patents
Verfahren zur Herstellung von basischen Phenothiazin-Derivaten, die in 3-Stellung mit einer einwertigen Schwefelfunktion substituiert sindInfo
- Publication number
- CH376505A CH376505A CH7686859A CH7686859A CH376505A CH 376505 A CH376505 A CH 376505A CH 7686859 A CH7686859 A CH 7686859A CH 7686859 A CH7686859 A CH 7686859A CH 376505 A CH376505 A CH 376505A
- Authority
- CH
- Switzerland
- Prior art keywords
- hydrogen atom
- general formula
- preparation
- substituted
- basic
- Prior art date
Links
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical group [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 title 1
- 125000001484 phenothiazinyl group Chemical class C1(=CC=CC=2SC3=CC=CC=C3NC12)* 0.000 title 1
- 229940066767 systemic antihistamines phenothiazine derivative Drugs 0.000 title 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 5
- GLUUGHFHXGJENI-UHFFFAOYSA-N Piperazine Chemical compound C1CNCCN1 GLUUGHFHXGJENI-UHFFFAOYSA-N 0.000 abstract 2
- GDTBXPJZTBHREO-UHFFFAOYSA-N bromine Chemical group BrBr GDTBXPJZTBHREO-UHFFFAOYSA-N 0.000 abstract 2
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 2
- 125000004178 (C1-C4) alkyl group Chemical group 0.000 abstract 1
- WJFKNYWRSNBZNX-UHFFFAOYSA-N 10H-phenothiazine Chemical compound C1=CC=C2NC3=CC=CC=C3SC2=C1 WJFKNYWRSNBZNX-UHFFFAOYSA-N 0.000 abstract 1
- ZWSGNPYAADGNPH-UHFFFAOYSA-N 3-ethyl-10H-phenothiazine-1-thiol Chemical compound C(C)C=1C=C(C=2NC3=CC=CC=C3SC2C1)S ZWSGNPYAADGNPH-UHFFFAOYSA-N 0.000 abstract 1
- ZCYVEMRRCGMTRW-UHFFFAOYSA-N 7553-56-2 Chemical group [I] ZCYVEMRRCGMTRW-UHFFFAOYSA-N 0.000 abstract 1
- MFESCIUQSIBMSM-UHFFFAOYSA-N I-BCP Chemical compound ClCCCBr MFESCIUQSIBMSM-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 229940100198 alkylating agent Drugs 0.000 abstract 1
- 239000002168 alkylating agent Substances 0.000 abstract 1
- 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 abstract 1
- 229910052794 bromium Inorganic materials 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 229910052801 chlorine Inorganic materials 0.000 abstract 1
- 239000000460 chlorine Substances 0.000 abstract 1
- 125000001309 chloro group Chemical group Cl* 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 229910052740 iodine Chemical group 0.000 abstract 1
- 229950000688 phenothiazine Drugs 0.000 abstract 1
- 150000002990 phenothiazines Chemical class 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D279/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one sulfur atom as the only ring hetero atoms
- C07D279/10—1,4-Thiazines; Hydrogenated 1,4-thiazines
- C07D279/14—1,4-Thiazines; Hydrogenated 1,4-thiazines condensed with carbocyclic rings or ring systems
- C07D279/18—[b, e]-condensed with two six-membered rings
- C07D279/22—[b, e]-condensed with two six-membered rings with carbon atoms directly attached to the ring nitrogen atom
- C07D279/24—[b, e]-condensed with two six-membered rings with carbon atoms directly attached to the ring nitrogen atom with hydrocarbon radicals, substituted by amino radicals, attached to the ring nitrogen atom
- C07D279/28—[b, e]-condensed with two six-membered rings with carbon atoms directly attached to the ring nitrogen atom with hydrocarbon radicals, substituted by amino radicals, attached to the ring nitrogen atom with other substituents attached to the ring system
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
Priority Applications (8)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH1543463A CH385848A (de) | 1959-08-12 | 1959-08-12 | Verfahren zur Herstellung von basischen Phenothiazin-Derivaten, die in 3-Stellung mit einer einwertigen Schwefelfunktion substituiert sind |
| CH7686859A CH376505A (de) | 1959-08-12 | 1959-08-12 | Verfahren zur Herstellung von basischen Phenothiazin-Derivaten, die in 3-Stellung mit einer einwertigen Schwefelfunktion substituiert sind |
| GB25800/60A GB932016A (en) | 1959-08-12 | 1960-07-25 | Process for the preparation of boric phenthiazines |
| NL254588A NL254588A (nl) | 1959-08-12 | 1960-08-05 | Werkwijze voor het bereiden van basische fenothiazinederivaten die op de plaats 3 door een éénwaardige zwavelfunktie gesubstitueerd zijn |
| SE770960A SE219927C1 (sv) | 1959-08-12 | 1960-08-10 | Förfarande för framställning av fentiazinderivat innehallande en piperazinrest och i 3-ställning en alkylmerkaptogrupp |
| BE593977A BE593977R (fr) | 1959-08-12 | 1960-08-10 | Nouveaux dérivés basiques de la 3-alcoylmercapto-phénothiazine substitués sur l'azote et leur préparation |
| FR835537A FR84257E (fr) | 1959-08-12 | 1960-08-10 | Nouveaux dérivés basiques de la 3-alcoylmercapto-phénothiazine substitués sur l'azote et leur préparation |
| ES0260288A ES260288A2 (es) | 1959-08-12 | 1960-08-10 | Procedimiento para la obtenciën de derivados feniotiacinicos basicos hasta ahora desconocidos |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH7686859A CH376505A (de) | 1959-08-12 | 1959-08-12 | Verfahren zur Herstellung von basischen Phenothiazin-Derivaten, die in 3-Stellung mit einer einwertigen Schwefelfunktion substituiert sind |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CH376505A true CH376505A (de) | 1964-04-15 |
Family
ID=4535219
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CH7686859A CH376505A (de) | 1959-08-12 | 1959-08-12 | Verfahren zur Herstellung von basischen Phenothiazin-Derivaten, die in 3-Stellung mit einer einwertigen Schwefelfunktion substituiert sind |
Country Status (7)
| Country | Link |
|---|---|
| BE (1) | BE593977R (fr) |
| CH (1) | CH376505A (fr) |
| ES (1) | ES260288A2 (fr) |
| FR (1) | FR84257E (fr) |
| GB (1) | GB932016A (fr) |
| NL (1) | NL254588A (fr) |
| SE (1) | SE219927C1 (fr) |
-
1959
- 1959-08-12 CH CH7686859A patent/CH376505A/de unknown
-
1960
- 1960-07-25 GB GB25800/60A patent/GB932016A/en not_active Expired
- 1960-08-05 NL NL254588A patent/NL254588A/nl unknown
- 1960-08-10 ES ES0260288A patent/ES260288A2/es not_active Expired
- 1960-08-10 BE BE593977A patent/BE593977R/fr active
- 1960-08-10 FR FR835537A patent/FR84257E/fr not_active Expired
- 1960-08-10 SE SE770960A patent/SE219927C1/sv unknown
Also Published As
| Publication number | Publication date |
|---|---|
| NL254588A (nl) | 1964-03-25 |
| GB932016A (en) | 1963-07-24 |
| FR84257E (fr) | 1965-01-08 |
| ES260288A2 (es) | 1961-04-01 |
| BE593977R (fr) | 1961-02-10 |
| SE219927C1 (sv) | 1968-04-09 |
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