CH401987A - Procédé d'extraction et de purification de l'acide glutamique - Google Patents

Procédé d'extraction et de purification de l'acide glutamique

Info

Publication number: CH401987A
Authority: CH; Switzerland
Prior art keywords: glutamic acid; acid; exchange resin; cation exchange; acidic cation
Prior art date: 1960-05-30

Application number

CH627261A

Other languages

English (en)

French (fr)

Inventor

Tanaka Masatami

Aoki Yoshiatsu

Original Assignee

Shinshin Food Ind Co Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1960-05-30

Filing date

1961-05-30

Publication date

1965-11-15

1961-05-30 Application filed by Shinshin Food Ind Co Ltd filed Critical Shinshin Food Ind Co Ltd

1965-11-15 Publication of CH401987A publication Critical patent/CH401987A/fr

Links

WHUUTDBJXJRKMK-UHFFFAOYSA-N Glutamic acid Natural products OC(=O)C(N)CCC(O)=O WHUUTDBJXJRKMK-UHFFFAOYSA-N 0.000 title claims description 38
235000013922 glutamic acid Nutrition 0.000 title claims description 37
239000004220 glutamic acid Substances 0.000 title claims description 37
238000000034 method Methods 0.000 title claims description 12
238000000605 extraction Methods 0.000 title claims description 3
238000000746 purification Methods 0.000 title claims description 3
230000002378 acidificating effect Effects 0.000 claims description 20
239000003729 cation exchange resin Substances 0.000 claims description 15
NWUYHJFMYQTDRP-UHFFFAOYSA-N 1,2-bis(ethenyl)benzene;1-ethenyl-2-ethylbenzene;styrene Chemical compound C=CC1=CC=CC=C1.CCC1=CC=CC=C1C=C.C=CC1=CC=CC=C1C=C NWUYHJFMYQTDRP-UHFFFAOYSA-N 0.000 claims description 14
HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 claims description 12
239000007788 liquid Substances 0.000 claims description 9
239000002253 acid Substances 0.000 claims description 8
238000001179 sorption measurement Methods 0.000 claims description 7
239000003513 alkali Substances 0.000 claims description 5
239000012535 impurity Substances 0.000 claims description 4
125000002091 cationic group Chemical group 0.000 claims description 3
VHUUQVKOLVNVRT-UHFFFAOYSA-N Ammonium hydroxide Chemical compound [NH4+].[OH-] VHUUQVKOLVNVRT-UHFFFAOYSA-N 0.000 claims 1
239000012670 alkaline solution Substances 0.000 claims 1
QGZKDVFQNNGYKY-UHFFFAOYSA-N ammonia Natural products N QGZKDVFQNNGYKY-UHFFFAOYSA-N 0.000 claims 1
239000000243 solution Substances 0.000 claims 1
150000001768 cations Chemical class 0.000 description 11
238000000855 fermentation Methods 0.000 description 10
230000004151 fermentation Effects 0.000 description 9
239000011347 resin Substances 0.000 description 9
229920005989 resin Polymers 0.000 description 9
VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 description 8
238000003795 desorption Methods 0.000 description 6
239000000047 product Substances 0.000 description 5
229920002125 Sokalan® Polymers 0.000 description 4
150000001450 anions Chemical class 0.000 description 4
150000002500 ions Chemical class 0.000 description 4
QGZKDVFQNNGYKY-UHFFFAOYSA-O Ammonium Chemical compound [NH4+] QGZKDVFQNNGYKY-UHFFFAOYSA-O 0.000 description 3
229920001429 chelating resin Polymers 0.000 description 3
239000000463 material Substances 0.000 description 3
235000011121 sodium hydroxide Nutrition 0.000 description 3
MYRTYDVEIRVNKP-UHFFFAOYSA-N 1,2-Divinylbenzene Chemical compound C=CC1=CC=CC=C1C=C MYRTYDVEIRVNKP-UHFFFAOYSA-N 0.000 description 2
230000001580 bacterial effect Effects 0.000 description 2
229940023913 cation exchange resins Drugs 0.000 description 2
239000003518 caustics Substances 0.000 description 2
239000003795 chemical substances by application Substances 0.000 description 2
238000001816 cooling Methods 0.000 description 2
238000002425 crystallisation Methods 0.000 description 2
230000008025 crystallization Effects 0.000 description 2
230000007423 decrease Effects 0.000 description 2
239000003792 electrolyte Substances 0.000 description 2
125000004435 hydrogen atom Chemical group [H]* 0.000 description 2
239000002244 precipitate Substances 0.000 description 2
150000003839 salts Chemical class 0.000 description 2
239000000126 substance Substances 0.000 description 2
XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 2
DPEYHNFHDIXMNV-UHFFFAOYSA-N (9-amino-3-bicyclo[3.3.1]nonanyl)-(4-benzyl-5-methyl-1,4-diazepan-1-yl)methanone dihydrochloride Chemical compound Cl.Cl.CC1CCN(CCN1Cc1ccccc1)C(=O)C1CC2CCCC(C1)C2N DPEYHNFHDIXMNV-UHFFFAOYSA-N 0.000 description 1
108010054404 Adenylyl-sulfate kinase Proteins 0.000 description 1
241000894006 Bacteria Species 0.000 description 1
WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 1
CERQOIWHTDAKMF-UHFFFAOYSA-N Methacrylic acid Chemical compound CC(=C)C(O)=O CERQOIWHTDAKMF-UHFFFAOYSA-N 0.000 description 1
102100039024 Sphingosine kinase 1 Human genes 0.000 description 1
235000001014 amino acid Nutrition 0.000 description 1
-1 amino acid ion Chemical class 0.000 description 1
125000000129 anionic group Chemical group 0.000 description 1
239000004202 carbamide Substances 0.000 description 1
150000001720 carbohydrates Chemical class 0.000 description 1
235000014633 carbohydrates Nutrition 0.000 description 1
BVKZGUZCCUSVTD-UHFFFAOYSA-N carbonic acid Chemical compound OC(O)=O BVKZGUZCCUSVTD-UHFFFAOYSA-N 0.000 description 1
238000004040 coloring Methods 0.000 description 1
150000001875 compounds Chemical class 0.000 description 1
239000013078 crystal Substances 0.000 description 1
238000012258 culturing Methods 0.000 description 1
238000000354 decomposition reaction Methods 0.000 description 1
230000000694 effects Effects 0.000 description 1
230000002349 favourable effect Effects 0.000 description 1
238000009950 felting Methods 0.000 description 1
238000001914 filtration Methods 0.000 description 1
239000008103 glucose Substances 0.000 description 1
239000003292 glue Substances 0.000 description 1
229910052500 inorganic mineral Inorganic materials 0.000 description 1
239000003456 ion exchange resin Substances 0.000 description 1
229920003303 ion-exchange polymer Polymers 0.000 description 1
239000011707 mineral Substances 0.000 description 1
235000010755 mineral Nutrition 0.000 description 1
239000012452 mother liquor Substances 0.000 description 1
230000007935 neutral effect Effects 0.000 description 1
235000008935 nutritious Nutrition 0.000 description 1
238000006116 polymerization reaction Methods 0.000 description 1
235000018102 proteins Nutrition 0.000 description 1
102000004169 proteins and genes Human genes 0.000 description 1
108090000623 proteins and genes Proteins 0.000 description 1
230000000630 rising effect Effects 0.000 description 1
238000012799 strong cation exchange Methods 0.000 description 1
XSQUKJJJFZCRTK-UHFFFAOYSA-N urea group Chemical group NC(=O)N XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 description 1

Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
- C12P13/04—Alpha- or beta- amino acids
- C12P13/14—Glutamic acid; Glutamine
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J39/00—Cation exchange; Use of material as cation exchangers; Treatment of material for improving the cation exchange properties
- B01J39/04—Processes using organic exchangers
- B01J39/05—Processes using organic exchangers in the strongly acidic form

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Wood Science & Technology (AREA)
Engineering & Computer Science (AREA)
Chemical Kinetics & Catalysis (AREA)
Zoology (AREA)
Life Sciences & Earth Sciences (AREA)
Microbiology (AREA)
Biotechnology (AREA)
General Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Biochemistry (AREA)
Bioinformatics & Cheminformatics (AREA)
General Engineering & Computer Science (AREA)
General Health & Medical Sciences (AREA)
Genetics & Genomics (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

CH627261A 1960-05-30 1961-05-30 Procédé d'extraction et de purification de l'acide glutamique CH401987A (fr)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
JP2566960		1960-05-30

Publications (1)

Publication Number	Publication Date
CH401987A true CH401987A (fr)	1965-11-15

Family

ID=12172175

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
CH627261A CH401987A (fr)	1960-05-30	1961-05-30	Procédé d'extraction et de purification de l'acide glutamique

Country Status (6)

Country	Link
US (1)	US3173949A (2)
BE (1)	BE604404A (2)
CH (1)	CH401987A (2)
DE (1)	DE1417603A1 (2)
GB (1)	GB947797A (2)
NL (2)	NL123588C (2)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO1997027170A1 (en) *	1996-01-22	1997-07-31	Amylum N.V.	A process for producing glutamic acid
WO1998003468A1 (en) *	1996-07-18	1998-01-29	Amylum N.V.	A process for the production of crystalline aspartic acid

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3331828A (en) *	1964-09-30	1967-07-18	Merck & Co Inc	Isolation of gamma-l-glutamyl dipeptides from glutamic acid fermentation broths by ion exchange

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US1973574A (en) *	1931-04-29	1934-09-11	Larrowe Suzuki Company	Process for manufacturing and recovering glutamic acid
US2738353A (en) *	1951-11-24	1956-03-13	Int Minerals & Chem Corp	Purification and recovery of pyrrolidone carboxylic acid
US3015655A (en) *	1955-07-18	1962-01-02	John B Stark	Separation of nitrogenous organic compounds

0
- NL NL265337D patent/NL265337A/xx unknown
- NL NL123588D patent/NL123588C/xx active
1961
- 1961-05-29 US US113078A patent/US3173949A/en not_active Expired - Lifetime
- 1961-05-29 GB GB19375/61A patent/GB947797A/en not_active Expired
- 1961-05-30 CH CH627261A patent/CH401987A/fr unknown
- 1961-05-30 DE DE19611417603 patent/DE1417603A1/de active Pending
- 1961-05-30 BE BE604404A patent/BE604404A/fr unknown

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO1997027170A1 (en) *	1996-01-22	1997-07-31	Amylum N.V.	A process for producing glutamic acid
US6147259A (en) *	1996-01-22	2000-11-14	Amylum N.V.	Process for producing glutamic acid
CN1125037C (zh) *	1996-01-22	2003-10-22	阿米卢姆公司	生产谷氨酸的方法
WO1998003468A1 (en) *	1996-07-18	1998-01-29	Amylum N.V.	A process for the production of crystalline aspartic acid

Also Published As

Publication number	Publication date
US3173949A (en)	1965-03-16
BE604404A (fr)	1961-09-18
DE1417603A1 (de)	1968-10-10
NL123588C (2)
NL265337A (2)
GB947797A (en)	1964-01-29

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