CH407133A - Verfahren zur Herstellung eines neuen Oxadiazolinderivates - Google Patents

Verfahren zur Herstellung eines neuen Oxadiazolinderivates

Info

Publication number: CH407133A
Authority: CH; Switzerland
Prior art keywords: salt; preparation; new; aminophenyl; hydroxy
Prior art date: 1962-12-21

Application number

CH1503162A

Other languages

German (de)

English (en)

Inventor

Erlenmeyer Hans Dr Prof

Original Assignee

Erlenmeyer Hans Dr Prof

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1962-12-21

Filing date

1962-12-21

Publication date

1966-02-15

1962-12-21 Application filed by Erlenmeyer Hans Dr Prof filed Critical Erlenmeyer Hans Dr Prof

1962-12-21 Priority to CH1503162A priority Critical patent/CH407133A/de

1963-12-18 Priority to AT1019163A priority patent/AT241458B/de

1964-03-16 Priority to FR967529A priority patent/FR3262M/fr

1966-02-15 Publication of CH407133A publication Critical patent/CH407133A/de

Links

238000000034 method Methods 0.000 title claims description 8
238000002360 preparation method Methods 0.000 title claims description 6
JKNSMBZZZFGYCB-UHFFFAOYSA-N 4,5-dihydrooxadiazole Chemical class C1CN=NO1 JKNSMBZZZFGYCB-UHFFFAOYSA-N 0.000 title description 3
150000003839 salts Chemical class 0.000 claims description 12
WUBBRNOQWQTFEX-UHFFFAOYSA-N 4-aminosalicylic acid Chemical compound NC1=CC=C(C(O)=O)C(O)=C1 WUBBRNOQWQTFEX-UHFFFAOYSA-N 0.000 claims description 9
229960004909 aminosalicylic acid Drugs 0.000 claims description 9
239000000243 solution Substances 0.000 claims description 4
239000007864 aqueous solution Substances 0.000 claims description 3
FVVDKUPCWXUVNP-UHFFFAOYSA-M Aminosalicylate sodium anhydrous Chemical compound [Na+].NC1=CC=C(C([O-])=O)C(O)=C1 FVVDKUPCWXUVNP-UHFFFAOYSA-M 0.000 claims description 2
VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 claims description 2
230000001419 dependent effect Effects 0.000 claims 2
LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 4
YXFVVABEGXRONW-UHFFFAOYSA-N Toluene Chemical compound CC1=CC=CC=C1 YXFVVABEGXRONW-UHFFFAOYSA-N 0.000 description 3
239000002244 precipitate Substances 0.000 description 3
QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 description 2
239000013078 crystal Substances 0.000 description 2
238000002844 melting Methods 0.000 description 2
230000008018 melting Effects 0.000 description 2
239000002904 solvent Substances 0.000 description 2
XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 2
RYHBNJHYFVUHQT-UHFFFAOYSA-N 1,4-Dioxane Chemical compound C1COCCO1 RYHBNJHYFVUHQT-UHFFFAOYSA-N 0.000 description 1
229960000583 acetic acid Drugs 0.000 description 1
239000002253 acid Substances 0.000 description 1
FYZGXAKJVDHGDR-UHFFFAOYSA-N aminosalicylic acid hydrazide Chemical compound NNC(=O)C1=CC=C(N)C=C1O FYZGXAKJVDHGDR-UHFFFAOYSA-N 0.000 description 1
229950008235 aminosalicylic acid hydrazide Drugs 0.000 description 1
150000001875 compounds Chemical class 0.000 description 1
239000012362 glacial acetic acid Substances 0.000 description 1
238000010438 heat treatment Methods 0.000 description 1
239000012047 saturated solution Substances 0.000 description 1
159000000000 sodium salts Chemical class 0.000 description 1
LMBFAGIMSUYTBN-MPZNNTNKSA-N teixobactin Chemical compound C([C@H](C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H](CCC(N)=O)C(=O)N[C@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H]1C(N[C@@H](C)C(=O)N[C@@H](C[C@@H]2NC(=N)NC2)C(=O)N[C@H](C(=O)O[C@H]1C)[C@@H](C)CC)=O)NC)C1=CC=CC=C1 LMBFAGIMSUYTBN-MPZNNTNKSA-N 0.000 description 1
230000001549 tubercolostatic effect Effects 0.000 description 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D271/00—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms
- C07D271/02—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms not condensed with other rings
- C07D271/10—1,3,4-Oxadiazoles; Hydrogenated 1,3,4-oxadiazoles
- C07D271/113—1,3,4-Oxadiazoles; Hydrogenated 1,3,4-oxadiazoles with oxygen, sulfur or nitrogen atoms, directly attached to ring carbon atoms, the nitrogen atoms not forming part of a nitro radical

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

CH1503162A 1962-12-21 1962-12-21 Verfahren zur Herstellung eines neuen Oxadiazolinderivates CH407133A (de)

Priority Applications (3)

Application Number	Priority Date	Filing Date	Title
CH1503162A CH407133A (de)	1962-12-21	1962-12-21	Verfahren zur Herstellung eines neuen Oxadiazolinderivates
AT1019163A AT241458B (de)	1962-12-21	1963-12-18	Verfahren zur Herstellung eines neuen Oxadiazolinderivates
FR967529A FR3262M (fr)	1962-12-21	1964-03-16	Nouveau médicament présentant notamment des propriétés tuberculostatiques.

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
CH1503162A CH407133A (de)	1962-12-21	1962-12-21	Verfahren zur Herstellung eines neuen Oxadiazolinderivates

Publications (1)

Publication Number	Publication Date
CH407133A true CH407133A (de)	1966-02-15

Family

ID=4405727

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
CH1503162A CH407133A (de)	1962-12-21	1962-12-21	Verfahren zur Herstellung eines neuen Oxadiazolinderivates

Country Status (3)

Country	Link
AT (1)	AT241458B (fr)
CH (1)	CH407133A (fr)
FR (1)	FR3262M (fr)

1962
- 1962-12-21 CH CH1503162A patent/CH407133A/de unknown
1963
- 1963-12-18 AT AT1019163A patent/AT241458B/de active
1964
- 1964-03-16 FR FR967529A patent/FR3262M/fr active Active

Also Published As

Publication number	Publication date
AT241458B (de)	1965-07-26
FR3262M (fr)	1965-04-20

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