CH409249A - Desinfizierende Kombination - Google Patents

Desinfizierende Kombination

Info

Publication number: CH409249A
Authority: CH; Switzerland
Prior art keywords: sep; dibromo; quinaldine; hydroxy; quinoline
Prior art date: 1960-07-15

Application number

CH811460A

Other languages

German (de)

English (en)

Inventor

Jean-Pierre Dr Bourquin

Arthur Dr Brack

Erhard Dr Schenker

Walter Dr Steffen

Rudolf Dr Griot

Original Assignee

Sandoz Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1960-07-15

Filing date

1960-07-15

Publication date

1966-03-15

Priority to NL257440D priority Critical patent/NL257440A/xx

1960-07-15 Application filed by Sandoz Ag filed Critical Sandoz Ag

1960-07-15 Priority to CH811460A priority patent/CH409249A/de

1960-12-21 Priority to BR125143/60A priority patent/BR6025143D0/pt

1960-12-21 Priority to FR847610A priority patent/FR1279601A/fr

1960-12-22 Priority to SE12463/60A priority patent/SE301809B/xx

1961-06-05 Priority to GB20196/61A priority patent/GB919269A/en

1961-07-13 Priority to ES0269104A priority patent/ES269104A1/es

1961-07-13 Priority to FR867992A priority patent/FR1311M/fr

1961-07-15 Priority to LU40403A priority patent/LU40403A1/xx

1964-02-12 Priority to CY27864A priority patent/CY278A/xx

1964-03-24 Priority to US354443A priority patent/US3298911A/en

1964-12-08 Priority to OA50785A priority patent/OA00705A/fr

1964-12-30 Priority to MY56/64A priority patent/MY6400056A/xx

1964-12-31 Priority to OA51494A priority patent/OA01247A/fr

1966-03-15 Publication of CH409249A publication Critical patent/CH409249A/de

Links

239000000645 desinfectant Substances 0.000 title claims description 5
ZDASUJMDVPTNTF-UHFFFAOYSA-N 5,7-dibromo-8-quinolinol Chemical compound C1=CN=C2C(O)=C(Br)C=C(Br)C2=C1 ZDASUJMDVPTNTF-UHFFFAOYSA-N 0.000 claims description 13
239000004480 active ingredient Substances 0.000 claims description 12
IJTPLVAAROHGGB-UHFFFAOYSA-N (5,7-dibromo-2-methylquinolin-8-yl) benzoate Chemical compound C12=NC(C)=CC=C2C(Br)=CC(Br)=C1OC(=O)C1=CC=CC=C1 IJTPLVAAROHGGB-UHFFFAOYSA-N 0.000 claims description 9
125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 claims description 5
WKBOTKDWSSQWDR-UHFFFAOYSA-N Bromine atom Chemical compound [Br] WKBOTKDWSSQWDR-UHFFFAOYSA-N 0.000 claims description 3
GDTBXPJZTBHREO-UHFFFAOYSA-N bromine Substances BrBr GDTBXPJZTBHREO-UHFFFAOYSA-N 0.000 claims description 3
229910052794 bromium Inorganic materials 0.000 claims description 3
229910052801 chlorine Inorganic materials 0.000 claims description 3
239000000460 chlorine Substances 0.000 claims description 3
239000001257 hydrogen Substances 0.000 claims description 3
229910052739 hydrogen Inorganic materials 0.000 claims description 3
UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 claims description 2
125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 claims description 2
ZAMOUSCENKQFHK-UHFFFAOYSA-N Chlorine atom Chemical compound [Cl] ZAMOUSCENKQFHK-UHFFFAOYSA-N 0.000 claims 1
230000001419 dependent effect Effects 0.000 claims 1
230000002421 anti-septic effect Effects 0.000 description 10
XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 8
VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 description 7
238000002360 preparation method Methods 0.000 description 7
239000013543 active substance Substances 0.000 description 5
239000000243 solution Substances 0.000 description 5
HEDRZPFGACZZDS-UHFFFAOYSA-N Chloroform Chemical compound ClC(Cl)Cl HEDRZPFGACZZDS-UHFFFAOYSA-N 0.000 description 4
244000052616 bacterial pathogen Species 0.000 description 4
230000002401 inhibitory effect Effects 0.000 description 4
244000005700 microbiome Species 0.000 description 4
239000000203 mixture Substances 0.000 description 4
239000002674 ointment Substances 0.000 description 4
WFDIJRYMOXRFFG-UHFFFAOYSA-N Acetic anhydride Chemical compound CC(=O)OC(C)=O WFDIJRYMOXRFFG-UHFFFAOYSA-N 0.000 description 3
UHOVQNZJYSORNB-UHFFFAOYSA-N Benzene Chemical compound C1=CC=CC=C1 UHOVQNZJYSORNB-UHFFFAOYSA-N 0.000 description 3
PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 3
235000019483 Peanut oil Nutrition 0.000 description 3
238000010790 dilution Methods 0.000 description 3
239000012895 dilution Substances 0.000 description 3
239000012153 distilled water Substances 0.000 description 3
238000002844 melting Methods 0.000 description 3
230000008018 melting Effects 0.000 description 3
239000000312 peanut oil Substances 0.000 description 3
229940068918 polyethylene glycol 400 Drugs 0.000 description 3
239000000843 powder Substances 0.000 description 3
239000000377 silicon dioxide Substances 0.000 description 3
239000000126 substance Substances 0.000 description 3
230000002195 synergetic effect Effects 0.000 description 3
VBICKXHEKHSIBG-UHFFFAOYSA-N 1-monostearoylglycerol Chemical compound CCCCCCCCCCCCCCCCCC(=O)OCC(O)CO VBICKXHEKHSIBG-UHFFFAOYSA-N 0.000 description 2
235000001674 Agaricus brunnescens Nutrition 0.000 description 2
FBPFZTCFMRRESA-FSIIMWSLSA-N D-Glucitol Natural products OC[C@H](O)[C@H](O)[C@@H](O)[C@H](O)CO FBPFZTCFMRRESA-FSIIMWSLSA-N 0.000 description 2
UIIMBOGNXHQVGW-UHFFFAOYSA-M Sodium bicarbonate Chemical compound [Na+].OC([O-])=O UIIMBOGNXHQVGW-UHFFFAOYSA-M 0.000 description 2
DPXJVFZANSGRMM-UHFFFAOYSA-N acetic acid;2,3,4,5,6-pentahydroxyhexanal;sodium Chemical compound [Na].CC(O)=O.OCC(O)C(O)C(O)C(O)C=O DPXJVFZANSGRMM-UHFFFAOYSA-N 0.000 description 2
PASDCCFISLVPSO-UHFFFAOYSA-N benzoyl chloride Chemical compound ClC(=O)C1=CC=CC=C1 PASDCCFISLVPSO-UHFFFAOYSA-N 0.000 description 2
239000001768 carboxy methyl cellulose Substances 0.000 description 2
125000001309 chloro group Chemical group Cl* 0.000 description 2
230000000249 desinfective effect Effects 0.000 description 2
230000000694 effects Effects 0.000 description 2
230000009036 growth inhibition Effects 0.000 description 2
235000015097 nutrients Nutrition 0.000 description 2
239000000546 pharmaceutical excipient Substances 0.000 description 2
229940057838 polyethylene glycol 4000 Drugs 0.000 description 2
239000001818 polyoxyethylene sorbitan monostearate Substances 0.000 description 2
235000010989 polyoxyethylene sorbitan monostearate Nutrition 0.000 description 2
235000019812 sodium carboxymethyl cellulose Nutrition 0.000 description 2
239000000600 sorbitol Substances 0.000 description 2
239000007921 spray Substances 0.000 description 2
239000003381 stabilizer Substances 0.000 description 2
239000000454 talc Substances 0.000 description 2
229910052623 talc Inorganic materials 0.000 description 2
210000002268 wool Anatomy 0.000 description 2
NOGFHTGYPKWWRX-UHFFFAOYSA-N 2,2,6,6-tetramethyloxan-4-one Chemical compound CC1(C)CC(=O)CC(C)(C)O1 NOGFHTGYPKWWRX-UHFFFAOYSA-N 0.000 description 1
HIQIXEFWDLTDED-UHFFFAOYSA-N 4-hydroxy-1-piperidin-4-ylpyrrolidin-2-one Chemical compound O=C1CC(O)CN1C1CCNCC1 HIQIXEFWDLTDED-UHFFFAOYSA-N 0.000 description 1
BNACJQWJZKPAPV-UHFFFAOYSA-N 5,7-dibromo-2-methylquinolin-8-ol Chemical compound BrC1=CC(Br)=C(O)C2=NC(C)=CC=C21 BNACJQWJZKPAPV-UHFFFAOYSA-N 0.000 description 1
ZCYVEMRRCGMTRW-UHFFFAOYSA-N 7553-56-2 Chemical compound [I] ZCYVEMRRCGMTRW-UHFFFAOYSA-N 0.000 description 1
241000222122 Candida albicans Species 0.000 description 1
241000233866 Fungi Species 0.000 description 1
WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 1
241000272476 Gyps Species 0.000 description 1
-1 Oleic oleyl ester Chemical class 0.000 description 1
240000004808 Saccharomyces cerevisiae Species 0.000 description 1
235000014680 Saccharomyces cerevisiae Nutrition 0.000 description 1
PMZURENOXWZQFD-UHFFFAOYSA-L Sodium Sulfate Chemical compound [Na+].[Na+].[O-]S([O-])(=O)=O PMZURENOXWZQFD-UHFFFAOYSA-L 0.000 description 1
WETWJCDKMRHUPV-UHFFFAOYSA-N acetyl chloride Chemical compound CC(Cl)=O WETWJCDKMRHUPV-UHFFFAOYSA-N 0.000 description 1
239000012346 acetyl chloride Substances 0.000 description 1
239000000654 additive Substances 0.000 description 1
230000000996 additive effect Effects 0.000 description 1
238000009835 boiling Methods 0.000 description 1
229940095731 candida albicans Drugs 0.000 description 1
MYSWGUAQZAJSOK-UHFFFAOYSA-N ciprofloxacin Chemical compound C12=CC(N3CCNCC3)=C(F)C=C2C(=O)C(C(=O)O)=CN1C1CC1 MYSWGUAQZAJSOK-UHFFFAOYSA-N 0.000 description 1
230000000295 complement effect Effects 0.000 description 1
238000001816 cooling Methods 0.000 description 1
239000003085 diluting agent Substances 0.000 description 1
239000008103 glucose Substances 0.000 description 1
YQEMORVAKMFKLG-UHFFFAOYSA-N glycerine monostearate Natural products CCCCCCCCCCCCCCCCCC(=O)OC(CO)CO YQEMORVAKMFKLG-UHFFFAOYSA-N 0.000 description 1
SVUQHVRAGMNPLW-UHFFFAOYSA-N glycerol monostearate Natural products CCCCCCCCCCCCCCCCC(=O)OCC(O)CO SVUQHVRAGMNPLW-UHFFFAOYSA-N 0.000 description 1
230000009422 growth inhibiting effect Effects 0.000 description 1
125000004435 hydrogen atom Chemical group [H]* 0.000 description 1
239000005457 ice water Substances 0.000 description 1
238000000338 in vitro Methods 0.000 description 1
238000001802 infusion Methods 0.000 description 1
229910052740 iodine Inorganic materials 0.000 description 1
PNDPGZBMCMUPRI-UHFFFAOYSA-N iodine Chemical compound II PNDPGZBMCMUPRI-UHFFFAOYSA-N 0.000 description 1
239000011630 iodine Substances 0.000 description 1
125000001449 isopropyl group Chemical group [H]C([H])([H])C([H])(*)C([H])([H])[H] 0.000 description 1
239000007788 liquid Substances 0.000 description 1
239000000463 material Substances 0.000 description 1
239000000155 melt Substances 0.000 description 1
230000009965 odorless effect Effects 0.000 description 1
BARWIPMJPCRCTP-UHFFFAOYSA-N oleic acid oleyl ester Natural products CCCCCCCCC=CCCCCCCCCOC(=O)CCCCCCCC=CCCCCCCCC BARWIPMJPCRCTP-UHFFFAOYSA-N 0.000 description 1
BARWIPMJPCRCTP-CLFAGFIQSA-N oleyl oleate Chemical compound CCCCCCCC\C=C/CCCCCCCCOC(=O)CCCCCCC\C=C/CCCCCCCC BARWIPMJPCRCTP-CLFAGFIQSA-N 0.000 description 1
230000001717 pathogenic effect Effects 0.000 description 1
238000001953 recrystallisation Methods 0.000 description 1
229910000030 sodium bicarbonate Inorganic materials 0.000 description 1
235000017557 sodium bicarbonate Nutrition 0.000 description 1
229920001027 sodium carboxymethylcellulose Polymers 0.000 description 1
229910052938 sodium sulfate Inorganic materials 0.000 description 1
235000011152 sodium sulphate Nutrition 0.000 description 1
239000000725 suspension Substances 0.000 description 1
230000009967 tasteless effect Effects 0.000 description 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Agricultural Chemicals And Associated Chemicals (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

CH811460A 1959-12-23 1960-07-15 Desinfizierende Kombination CH409249A (de)

Priority Applications (14)

Application Number	Priority Date	Filing Date	Title
NL257440D NL257440A (fr)	1959-12-23
CH811460A CH409249A (de)	1960-07-15	1960-07-15	Desinfizierende Kombination
BR125143/60A BR6025143D0 (pt)	1959-12-23	1960-12-21	Processo para a preparacao de novos esteres de 5,7-dihalogeno-8-oxiquinaldinas
FR847610A FR1279601A (fr)	1959-12-23	1960-12-21	Nouveaux esters de 5. 7-dihalogéno-8-hydroxy-quinaldines et leur préparation
SE12463/60A SE301809B (fr)	1959-12-23	1960-12-22
GB20196/61A GB919269A (en)	1959-12-23	1961-06-05	Antiseptic compositions comprising quinaldine derivatives
FR867992A FR1311M (fr)	1960-07-15	1961-07-13	Association de dérivés de la quinoléine et de la quinaldine, utilisable en particulier comme antiseptique.
ES0269104A ES269104A1 (es)	1960-07-15	1961-07-13	Procedimiento de obtenciën de una composiciën antiseptica
LU40403A LU40403A1 (fr)	1959-12-23	1961-07-15
CY27864A CY278A (en)	1959-12-23	1964-02-12	Antiseptic compositions comprising
US354443A US3298911A (en)	1959-12-23	1964-03-24	Bacteriostatic and fungicidal composition comprising 5, 7-dibromo-8-benzoyloxy-quinaldine in inert carrier
OA50785A OA00705A (fr)	1959-12-23	1964-12-08	Nouveaux esters de 5.7-dihalogéno-8-hydroxy-quinaldines et leur préparation.
MY56/64A MY6400056A (en)	1959-12-23	1964-12-30	Antiseptic compositions comprising quinaldine derivatives
OA51494A OA01247A (fr)	1960-07-15	1964-12-31	Composition antiseptique à base de dérivés de la quinoléine et de la quinaldine.

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
CH811460A CH409249A (de)	1960-07-15	1960-07-15	Desinfizierende Kombination

Publications (1)

Publication Number	Publication Date
CH409249A true CH409249A (de)	1966-03-15

Family

ID=4335384

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
CH811460A CH409249A (de)	1959-12-23	1960-07-15	Desinfizierende Kombination

Country Status (4)

Country	Link
CH (1)	CH409249A (fr)
ES (1)	ES269104A1 (fr)
FR (1)	FR1311M (fr)
OA (1)	OA01247A (fr)

1960
- 1960-07-15 CH CH811460A patent/CH409249A/de unknown
1961
- 1961-07-13 FR FR867992A patent/FR1311M/fr not_active Expired
- 1961-07-13 ES ES0269104A patent/ES269104A1/es not_active Expired
1964
- 1964-12-31 OA OA51494A patent/OA01247A/fr unknown

Also Published As

Publication number	Publication date
OA01247A (fr)	1969-01-25
ES269104A1 (es)	1962-03-16
FR1311M (fr)	1962-05-14

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CH630881A5 (de)	1982-07-15	Verfahren zur herstellung neuer substituierter fluoracylresorcine.
DE2510525C3 (de)	1978-03-30	Quartäre 2-Alkylimidazoliumsalze
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DE1141051B (de)	1962-12-13	Desinfektionsmittelgemisch
DE2157272C3 (de)	1979-03-01	Verwendung von bis-(p-Chlorphenoxy)acetylharnstoff
DE2019504C3 (de)	1980-10-02	Oxim-N-acylcarbamate, Verfahren zu ihrer Herstellung und ihre Verwendung zur Schädlingsbekämpfung
CH409249A (de)	1966-03-15	Desinfizierende Kombination
DE1695763C3 (de)	1975-06-12	Cyclopropancarbonsäureester
AT228941B (de)	1963-08-12	Verfahren zur Herstellung eines Desinfektionsmittels
DE2002800C3 (de)	1979-07-26	Benzo [b] thiophen-l,l-dioxidverbindungen und Verfahren zu ihrer Herstellung
DE1080998B (de)	1960-05-05	Verfahren zur Herstellung der als Herbicid dienenden 2, 3, 6-Tri-chlorphenylessigsaeure oder ihrer Salze, Ester, Amide oder Halogenide
DE2553270A1 (de)	1977-06-02	Ektoparasitizide mittel enthaltend diphenylcarbodiimide
DE2156967C3 (de)	1980-07-10	N-(4-Fluorphenyl)-23-dichlormaleinimid, Verfahren zu dessen Herstellung und diese Verbindung enthaltende Schädlingsbekämpfungsmittel
AT239440B (de)	1965-04-12	Verfahren zur Herstellung von neuen Derivaten der 6-Amino-Penicillansäure
AT208368B (de)	1960-04-11	Phytohormonale Mittel
DE938249C (de)	1956-01-26	Verfahren zur Herstellung von Dihydrocodeinhydrorhodanid
DE1209116C2 (de)	1974-04-25	Verfahren zur herstellung eines vitamin b tief 1 -disulfidabkoemmlings
DE2145686C3 (de)	1978-02-16	2-Chlor-S-sulfamylbenzoesäurederivate, Verfahren zu ihrer Herstellung und Arzneimittel, die diese Verbindungen enthalten
DE1806119C (de)	1971-09-30	Herbizide Mittel
DE1951156B1 (de)	1970-10-22	Biocide Zubereitung
CH442862A (de)	1967-08-31	Verfahren und Mittel zur Regelung des Pflanzenwachstums
DE2224508B2 (de)	1974-08-01	Wässrige Weichmacher-Zubereitung
DE1793634C3 (de)	1974-10-24	2-Vinylpyromekonsäure und deren nicht giftige Salze sowie Verfahren zu deren Herstellung. Ausscheidung aus: 1518098
DE1951795C (de)	1972-09-07	Verfahren zum Stabilisieren von Zink bzw Mangan athylen bis dithio-carbamat doer von diese enthaltenden fungiziden Gemischen
AT134632B (de)	1933-09-11	Desinfektions- und Waschmittel.