CH420176A - Process for the preparation of benzodiazepine derivatives - Google Patents

Process for the preparation of benzodiazepine derivatives

Info

Publication number
CH420176A
CH420176A CH1229962A CH1229962A CH420176A CH 420176 A CH420176 A CH 420176A CH 1229962 A CH1229962 A CH 1229962A CH 1229962 A CH1229962 A CH 1229962A CH 420176 A CH420176 A CH 420176A
Authority
CH
Switzerland
Prior art keywords
preparation
benzodiazepine derivatives
benzodiazepine
derivatives
Prior art date
Application number
CH1229962A
Other languages
German (de)
Inventor
Reeder Earl
Henryk Sternbach Leo
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US149527A external-priority patent/US3136815A/en
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of CH420176A publication Critical patent/CH420176A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D243/00Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/141,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C07D243/161,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
    • C07D243/181,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
    • C07D243/24Oxygen atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D243/00Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/141,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C07D243/161,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
    • C07D243/181,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
    • C07D243/24Oxygen atoms
    • C07D243/26Preparation from compounds already containing the benzodiazepine skeleton

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
CH1229962A 1961-11-02 1962-10-19 Process for the preparation of benzodiazepine derivatives CH420176A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US149527A US3136815A (en) 1959-12-10 1961-11-02 Amino substituted benzophenone oximes and derivatives thereof

Publications (1)

Publication Number Publication Date
CH420176A true CH420176A (en) 1966-09-15

Family

ID=22530691

Family Applications (2)

Application Number Title Priority Date Filing Date
CH1230062A CH420177A (en) 1961-11-02 1962-10-19 Process for the preparation of benzodiazepine derivatives
CH1229962A CH420176A (en) 1961-11-02 1962-10-19 Process for the preparation of benzodiazepine derivatives

Family Applications Before (1)

Application Number Title Priority Date Filing Date
CH1230062A CH420177A (en) 1961-11-02 1962-10-19 Process for the preparation of benzodiazepine derivatives

Country Status (8)

Country Link
BE (2) BE624168A (en)
BR (1) BR6244259D0 (en)
CH (2) CH420177A (en)
DK (2) DK116287B (en)
ES (2) ES282088A1 (en)
FR (1) FR2979M (en)
GB (2) GB988635A (en)
SE (2) SE302126B (en)

Also Published As

Publication number Publication date
BE624168A (en) 1963-04-29
DK116287B (en) 1969-12-29
FR2979M (en) 1964-12-07
ES282088A1 (en) 1963-03-16
SE301980B (en) 1968-07-01
ES282087A1 (en) 1963-03-16
GB988635A (en) 1965-04-07
DE1445865A1 (en) 1969-03-13
DE1445866A1 (en) 1969-03-13
BE624169A (en) 1963-04-29
BR6244259D0 (en) 1973-05-24
SE302126B (en) 1968-07-08
CH420177A (en) 1966-09-15
GB988634A (en) 1965-04-07
DK116365B (en) 1970-01-05

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