CH478818A - Verfahren zur Herstellung neuer N,N'-Di-(pyrimidyl-(4)-aminoalkyl)-diazacycloalkanen - Google Patents

Verfahren zur Herstellung neuer N,N'-Di-(pyrimidyl-(4)-aminoalkyl)-diazacycloalkanen

Info

Publication number
CH478818A
CH478818A CH506468A CH506468A CH478818A CH 478818 A CH478818 A CH 478818A CH 506468 A CH506468 A CH 506468A CH 506468 A CH506468 A CH 506468A CH 478818 A CH478818 A CH 478818A
Authority
CH
Switzerland
Prior art keywords
diazacycloalkanes
pyrimidyl
aminoalkyl
preparation
new
Prior art date
Application number
CH506468A
Other languages
English (en)
Inventor
Ernst Dr Schweizer
Original Assignee
Ciba Geigy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy filed Critical Ciba Geigy
Priority to CH1751468A priority Critical patent/CH499528A/de
Priority to CH1463065A priority patent/CH478816A/de
Priority to CH506468A priority patent/CH478818A/de
Priority to CH506568A priority patent/CH478819A/de
Priority to CH506368A priority patent/CH478817A/de
Priority to IL26473A priority patent/IL26473A/en
Priority to SU1106159A priority patent/SU436494A3/ru
Priority to SU1335465A priority patent/SU427513A3/ru
Priority to FR80113A priority patent/FR1500479A/fr
Priority to DE19661670392 priority patent/DE1670392A1/de
Priority to GB46245/66A priority patent/GB1135259A/en
Priority to BE688660D priority patent/BE688660A/xx
Priority to BR183919/66A priority patent/BR6683919D0/pt
Priority to NL6614961A priority patent/NL6614961A/xx
Priority to SE14418/66A priority patent/SE345273B/xx
Priority to US597870A priority patent/US3503963A/en
Priority to FR90061A priority patent/FR6083M/fr
Priority to FR90062A priority patent/FR6084M/fr
Publication of CH478818A publication Critical patent/CH478818A/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/50—Three nitrogen atoms
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
CH506468A 1965-10-22 1965-10-22 Verfahren zur Herstellung neuer N,N'-Di-(pyrimidyl-(4)-aminoalkyl)-diazacycloalkanen CH478818A (de)

Priority Applications (18)

Application Number Priority Date Filing Date Title
CH1751468A CH499528A (de) 1965-10-22 1965-10-22 Verfahren zur Herstellung neuer Pyrimidine
CH1463065A CH478816A (de) 1965-10-22 1965-10-22 Verfahren zur Herstellung neuer N,N'-Di-(pyrimidyl-(4)-aminoalkyl)-diazacycloalkanen
CH506468A CH478818A (de) 1965-10-22 1965-10-22 Verfahren zur Herstellung neuer N,N'-Di-(pyrimidyl-(4)-aminoalkyl)-diazacycloalkanen
CH506568A CH478819A (de) 1965-10-22 1965-10-22 Verfahren zur Herstellung neuer N,N'-Di-(pyrimidyl-(4)-aminoalkyl)-diazacycloalkanen
CH506368A CH478817A (de) 1965-10-22 1965-10-22 Verfahren zur Herstellung neuer N,N'-Di-(pyrimidyl-(4)-aminoalkyl)-diazacycloalkanen
IL26473A IL26473A (en) 1965-10-22 1966-09-07 4,1-Bis- (4-pyrimidylamino-alkyl) piperazines and process for their production
SU1106159A SU436494A3 (ru) 1965-10-22 1966-10-07 Способ получения n,n'-ди[пиpиmидил-
SU1335465A SU427513A3 (ru) 1965-10-22 1966-10-07 Способ получения производных пиримидина
FR80113A FR1500479A (fr) 1965-10-22 1966-10-14 Nouvelles pyrimidines et procédé pour les préparer
DE19661670392 DE1670392A1 (de) 1965-10-22 1966-10-14 Neue Pyrimidine und Verfahren zu ihrer Herstellung
GB46245/66A GB1135259A (en) 1965-10-22 1966-10-17 New pyrimidines and process for their manufacture
BE688660D BE688660A (de) 1965-10-22 1966-10-21
BR183919/66A BR6683919D0 (pt) 1965-10-22 1966-10-21 Processo para a fabricacao de novas pirimidinas
NL6614961A NL6614961A (de) 1965-10-22 1966-10-21
SE14418/66A SE345273B (de) 1965-10-22 1966-10-21
US597870A US3503963A (en) 1965-10-22 1966-11-30 N,n'-di-(pyrmidyl-(4)-aminoalkyl)-diazacycloalkanes
FR90061A FR6083M (de) 1965-10-22 1967-01-05
FR90062A FR6084M (de) 1965-10-22 1967-01-05

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
CH1463065A CH478816A (de) 1965-10-22 1965-10-22 Verfahren zur Herstellung neuer N,N'-Di-(pyrimidyl-(4)-aminoalkyl)-diazacycloalkanen
CH506468A CH478818A (de) 1965-10-22 1965-10-22 Verfahren zur Herstellung neuer N,N'-Di-(pyrimidyl-(4)-aminoalkyl)-diazacycloalkanen
CH506568A CH478819A (de) 1965-10-22 1965-10-22 Verfahren zur Herstellung neuer N,N'-Di-(pyrimidyl-(4)-aminoalkyl)-diazacycloalkanen
CH506368A CH478817A (de) 1965-10-22 1965-10-22 Verfahren zur Herstellung neuer N,N'-Di-(pyrimidyl-(4)-aminoalkyl)-diazacycloalkanen
CH1751468A CH499528A (de) 1965-10-22 1965-10-22 Verfahren zur Herstellung neuer Pyrimidine
CH1133066 1966-08-05

Publications (1)

Publication Number Publication Date
CH478818A true CH478818A (de) 1969-09-30

Family

ID=27543760

Family Applications (5)

Application Number Title Priority Date Filing Date
CH1751468A CH499528A (de) 1965-10-22 1965-10-22 Verfahren zur Herstellung neuer Pyrimidine
CH506368A CH478817A (de) 1965-10-22 1965-10-22 Verfahren zur Herstellung neuer N,N'-Di-(pyrimidyl-(4)-aminoalkyl)-diazacycloalkanen
CH506568A CH478819A (de) 1965-10-22 1965-10-22 Verfahren zur Herstellung neuer N,N'-Di-(pyrimidyl-(4)-aminoalkyl)-diazacycloalkanen
CH506468A CH478818A (de) 1965-10-22 1965-10-22 Verfahren zur Herstellung neuer N,N'-Di-(pyrimidyl-(4)-aminoalkyl)-diazacycloalkanen
CH1463065A CH478816A (de) 1965-10-22 1965-10-22 Verfahren zur Herstellung neuer N,N'-Di-(pyrimidyl-(4)-aminoalkyl)-diazacycloalkanen

Family Applications Before (3)

Application Number Title Priority Date Filing Date
CH1751468A CH499528A (de) 1965-10-22 1965-10-22 Verfahren zur Herstellung neuer Pyrimidine
CH506368A CH478817A (de) 1965-10-22 1965-10-22 Verfahren zur Herstellung neuer N,N'-Di-(pyrimidyl-(4)-aminoalkyl)-diazacycloalkanen
CH506568A CH478819A (de) 1965-10-22 1965-10-22 Verfahren zur Herstellung neuer N,N'-Di-(pyrimidyl-(4)-aminoalkyl)-diazacycloalkanen

Family Applications After (1)

Application Number Title Priority Date Filing Date
CH1463065A CH478816A (de) 1965-10-22 1965-10-22 Verfahren zur Herstellung neuer N,N'-Di-(pyrimidyl-(4)-aminoalkyl)-diazacycloalkanen

Country Status (11)

Country Link
US (1) US3503963A (de)
BE (1) BE688660A (de)
BR (1) BR6683919D0 (de)
CH (5) CH499528A (de)
DE (1) DE1670392A1 (de)
FR (3) FR1500479A (de)
GB (1) GB1135259A (de)
IL (1) IL26473A (de)
NL (1) NL6614961A (de)
SE (1) SE345273B (de)
SU (2) SU427513A3 (de)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH485754A (de) * 1966-07-28 1970-02-15 Ciba Geigy Verfahren zur Herstellung neuer Aminopyrimidine
RS20050532A (sr) 2003-01-14 2007-12-31 Arena Pharmaceuticals Inc., Derivati 1,2,3-trisupstituisanog arila i heteroarila kao modulatori metabolizma za profilaksu i tretman poremećaja povezanih sa njim, kao što su dijebetes i hiperglikemija
DE602004017703D1 (de) * 2003-02-24 2008-12-24 Arena Pharm Inc Phenyl- und pyridylpiperidinderivate als modulatoren des glucose-metabolismus
AR045047A1 (es) 2003-07-11 2005-10-12 Arena Pharm Inc Derivados arilo y heteroarilo trisustituidos como moduladores del metabolismo y de la profilaxis y tratamiento de desordenes relacionados con los mismos
EA011671B1 (ru) * 2004-06-04 2009-04-28 Арена Фармасьютикалз, Инк. Замещенные производные арила и гетероарила в качестве модуляторов метаболизма и для профилактики и лечения связанных с ним расстройств
HN2005000795A (es) * 2004-10-15 2010-08-19 Aventis Pharma Inc Pirimidinas como antagonistas del receptor de prostaglandina d2
MY148521A (en) * 2005-01-10 2013-04-30 Arena Pharm Inc Substituted pyridinyl and pyrimidinyl derivatives as modulators of metabolism and the treatment of disorders related thereto
DOP2006000010A (es) 2005-01-10 2006-07-31 Arena Pharm Inc Procedimiento para preparar eteres aromáticos
BRPI0616245A2 (pt) * 2005-09-16 2011-06-14 Arena Pharm Inc modulador de metabolismo, seus usos, composiÇço farmaceutica compreendendo o mesmo, bem como mÉtodo para produÇço da referida composiÇço
TW200811147A (en) * 2006-07-06 2008-03-01 Arena Pharm Inc Modulators of metabolism and the treatment of disorders related thereto
TW200811140A (en) * 2006-07-06 2008-03-01 Arena Pharm Inc Modulators of metabolism and the treatment of disorders related thereto
EP2528894A1 (de) 2010-01-27 2012-12-05 Arena Pharmaceuticals, Inc. Verfahren zur herstellung von (r)-2-(7-(4-cyclopentyl-3-(trifluoromethyl)benzyloxy)-1,2,3,4-tetrahydrocyclopenta[b]indol-3-yl)essigsäure und salzen daraus
CN103221410B (zh) 2010-09-22 2017-09-15 艾尼纳制药公司 Gpr119受体调节剂和对与其相关的障碍的治疗
CA3002540C (en) 2015-01-06 2023-11-07 Arena Pharmaceuticals, Inc. Use of (r)-2-(7-(4-cyclopentyl-3-(trifluoromethyl)benzyloxy)-1,2,3,4-tetrahydrocyclopenta[b]indol-3-yl)acetic acid for treating conditions related to the s1p1 receptor
JP6838744B2 (ja) 2015-06-22 2021-03-03 アリーナ ファーマシューティカルズ， インコーポレイテッド Ｓ１Ｐ１レセプター関連障害における使用のための（Ｒ）−２−（７−（４−シクロペンチル−３−（トリフルオロメチル）ベンジルオキシ）−１，２，３，４−テトラヒドロシクロペンタ［ｂ］インドール−３−イル）酢酸（化合物１）の結晶性Ｌ−アルギニン塩
CN110520124A (zh) 2017-02-16 2019-11-29 艾尼纳制药公司 用于治疗原发性胆汁性胆管炎的化合物和方法
JP7397011B2 (ja) 2018-06-06 2023-12-12 アリーナ ファーマシューティカルズ， インコーポレイテッド Ｓ１ｐ１受容体に関連する状態を治療する方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB944443A (de) * 1959-09-25 1900-01-01

Also Published As

Publication number Publication date
NL6614961A (de) 1967-04-24
SU436494A3 (ru) 1974-07-15
SE345273B (de) 1972-05-23
CH478816A (de) 1969-09-30
FR6083M (de) 1968-06-04
US3503963A (en) 1970-03-31
CH478819A (de) 1969-09-30
GB1135259A (en) 1968-12-04
SU427513A3 (ru) 1974-05-05
CH499528A (de) 1970-11-30
CH478817A (de) 1969-09-30
DE1670392A1 (de) 1970-07-16
FR1500479A (fr) 1967-11-03
FR6084M (de) 1968-06-04
BE688660A (de) 1967-04-21
BR6683919D0 (pt) 1973-12-04
IL26473A (en) 1971-08-25

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Legal Events

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PL Patent ceased