CH494034A - Mundpflegemittel - Google Patents

Mundpflegemittel

Info

Publication number: CH494034A
Authority: CH; Switzerland
Prior art keywords: sep; tin; diphosphonate; ditin; fluoride
Prior art date: 1966-12-29

Application number

CH1824167A

Other languages

German (de)

English (en)

Inventor

John Grabenstetter Robert

Stone Widder James

Stone Griebstein William

Original Assignee

Procter & Gamble

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1966-12-29

Filing date

1967-12-28

Publication date

1970-07-31

1967-12-28 Application filed by Procter & Gamble filed Critical Procter & Gamble

1970-07-31 Publication of CH494034A publication Critical patent/CH494034A/de

Links

208000002925 dental caries Diseases 0.000 title claims abstract description 14
239000000203 mixture Substances 0.000 title abstract description 12
ABLZXFCXXLZCGV-UHFFFAOYSA-N Phosphorous acid Chemical class OP(O)=O ABLZXFCXXLZCGV-UHFFFAOYSA-N 0.000 title 1
150000003839 salts Chemical class 0.000 claims abstract description 16
KRHYYFGTRYWZRS-UHFFFAOYSA-M Fluoride anion Chemical compound [F-] KRHYYFGTRYWZRS-UHFFFAOYSA-M 0.000 claims abstract description 13
125000004432 carbon atom Chemical group C* 0.000 claims abstract description 9
125000000217 alkyl group Chemical group 0.000 claims abstract description 7
125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 claims abstract description 6
229910052736 halogen Inorganic materials 0.000 claims abstract description 6
150000002367 halogens Chemical class 0.000 claims abstract description 6
125000002768 hydroxyalkyl group Chemical group 0.000 claims abstract description 6
238000011321 prophylaxis Methods 0.000 claims abstract description 4
125000002777 acetyl group Chemical group [H]C([H])([H])C(*)=O 0.000 claims abstract description 3
125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 claims abstract description 3
IUTCEZPPWBHGIX-UHFFFAOYSA-N tin(2+) Chemical class [Sn+2] IUTCEZPPWBHGIX-UHFFFAOYSA-N 0.000 claims description 18
239000003795 chemical substances by application Substances 0.000 claims description 11
MBKDYNNUVRNNRF-UHFFFAOYSA-N medronic acid Chemical compound OP(O)(=O)CP(O)(O)=O MBKDYNNUVRNNRF-UHFFFAOYSA-N 0.000 claims description 8
239000001257 hydrogen Substances 0.000 claims description 4
229910052739 hydrogen Inorganic materials 0.000 claims description 4
125000002887 hydroxy group Chemical group [H]O* 0.000 claims description 4
ANOBYBYXJXCGBS-UHFFFAOYSA-L stannous fluoride Chemical compound F[Sn]F ANOBYBYXJXCGBS-UHFFFAOYSA-L 0.000 claims description 3
125000004435 hydrogen atom Chemical group [H]* 0.000 claims 2
239000002253 acid Substances 0.000 abstract description 7
230000000694 effects Effects 0.000 abstract description 7
150000007513 acids Chemical class 0.000 abstract description 6
DBVJJBKOTRCVKF-UHFFFAOYSA-N Etidronic acid Chemical compound OP(=O)(O)C(O)(C)P(O)(O)=O DBVJJBKOTRCVKF-UHFFFAOYSA-N 0.000 abstract description 4
125000004181 carboxyalkyl group Chemical group 0.000 abstract 2
KNEOUPRMFAIKME-UHFFFAOYSA-N P(=O)(O)OP(=O)O.C Chemical compound P(=O)(O)OP(=O)O.C KNEOUPRMFAIKME-UHFFFAOYSA-N 0.000 abstract 1
230000002272 anti-calculus Effects 0.000 abstract 1
230000000675 anti-caries Effects 0.000 abstract 1
125000004429 atom Chemical group 0.000 abstract 1
-1 tin (II) ions Chemical class 0.000 description 30
ATJFFYVFTNAWJD-UHFFFAOYSA-N Tin Chemical compound [Sn] ATJFFYVFTNAWJD-UHFFFAOYSA-N 0.000 description 24
239000000606 toothpaste Substances 0.000 description 20
210000003298 dental enamel Anatomy 0.000 description 18
239000000047 product Substances 0.000 description 17
XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 16
IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 description 12
239000000243 solution Substances 0.000 description 12
150000001875 compounds Chemical class 0.000 description 11
238000000034 method Methods 0.000 description 10
CSCPPACGZOOCGX-UHFFFAOYSA-N Acetone Chemical compound CC(C)=O CSCPPACGZOOCGX-UHFFFAOYSA-N 0.000 description 9
238000002360 preparation method Methods 0.000 description 9
LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 8
238000004140 cleaning Methods 0.000 description 8
239000002324 mouth wash Substances 0.000 description 8
230000032683 aging Effects 0.000 description 7
239000012153 distilled water Substances 0.000 description 7
239000004088 foaming agent Substances 0.000 description 7
PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 6
DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 description 6
229910021626 Tin(II) chloride Inorganic materials 0.000 description 6
229940051866 mouthwash Drugs 0.000 description 6
229910052757 nitrogen Inorganic materials 0.000 description 6
239000011734 sodium Substances 0.000 description 6
229910052708 sodium Inorganic materials 0.000 description 6
JVTAAEKCZFNVCJ-UHFFFAOYSA-M Lactate Chemical compound CC(O)C([O-])=O JVTAAEKCZFNVCJ-UHFFFAOYSA-M 0.000 description 5
239000007864 aqueous solution Substances 0.000 description 5
230000015572 biosynthetic process Effects 0.000 description 5
XQRLCLUYWUNEEH-UHFFFAOYSA-L diphosphonate(2-) Chemical compound [O-]P(=O)OP([O-])=O XQRLCLUYWUNEEH-UHFFFAOYSA-L 0.000 description 5
150000002222 fluorine compounds Chemical class 0.000 description 5
238000006460 hydrolysis reaction Methods 0.000 description 5
239000006072 paste Substances 0.000 description 5
238000003756 stirring Methods 0.000 description 5
239000002562 thickening agent Substances 0.000 description 5
229940034610 toothpaste Drugs 0.000 description 5
238000011282 treatment Methods 0.000 description 5
208000006558 Dental Calculus Diseases 0.000 description 4
KRHYYFGTRYWZRS-UHFFFAOYSA-N Fluorane Chemical compound F KRHYYFGTRYWZRS-UHFFFAOYSA-N 0.000 description 4
230000007423 decrease Effects 0.000 description 4
KWIUHFFTVRNATP-UHFFFAOYSA-N glycine betaine Chemical compound C[N+](C)(C)CC([O-])=O KWIUHFFTVRNATP-UHFFFAOYSA-N 0.000 description 4
230000007062 hydrolysis Effects 0.000 description 4
229920005989 resin Polymers 0.000 description 4
239000011347 resin Substances 0.000 description 4
235000011150 stannous chloride Nutrition 0.000 description 4
AXZWODMDQAVCJE-UHFFFAOYSA-L tin(II) chloride (anhydrous) Chemical compound [Cl-].[Cl-].[Sn+2] AXZWODMDQAVCJE-UHFFFAOYSA-L 0.000 description 4
GEZAUFNYMZVOFV-UHFFFAOYSA-J 2-[(2-oxo-1,3,2$l^{5},4$l^{2}-dioxaphosphastannetan-2-yl)oxy]-1,3,2$l^{5},4$l^{2}-dioxaphosphastannetane 2-oxide Chemical compound [Sn+2].[Sn+2].[O-]P([O-])(=O)OP([O-])([O-])=O GEZAUFNYMZVOFV-UHFFFAOYSA-J 0.000 description 3
OTMSDBZUPAUEDD-UHFFFAOYSA-N Ethane Chemical compound CC OTMSDBZUPAUEDD-UHFFFAOYSA-N 0.000 description 3
WSFSSNUMVMOOMR-UHFFFAOYSA-N Formaldehyde Chemical compound O=C WSFSSNUMVMOOMR-UHFFFAOYSA-N 0.000 description 3
229910019142 PO4 Inorganic materials 0.000 description 3
230000008901 benefit Effects 0.000 description 3
239000000872 buffer Substances 0.000 description 3
229940112822 chewing gum Drugs 0.000 description 3
235000015218 chewing gum Nutrition 0.000 description 3
239000000470 constituent Substances 0.000 description 3
235000014113 dietary fatty acids Nutrition 0.000 description 3
235000019441 ethanol Nutrition 0.000 description 3
239000000194 fatty acid Substances 0.000 description 3
229930195729 fatty acid Natural products 0.000 description 3
239000000796 flavoring agent Substances 0.000 description 3
235000019634 flavors Nutrition 0.000 description 3
235000003599 food sweetener Nutrition 0.000 description 3
235000011187 glycerol Nutrition 0.000 description 3
239000003906 humectant Substances 0.000 description 3
VLKZOEOYAKHREP-UHFFFAOYSA-N n-Hexane Chemical compound CCCCCC VLKZOEOYAKHREP-UHFFFAOYSA-N 0.000 description 3
235000021317 phosphate Nutrition 0.000 description 3
150000003013 phosphoric acid derivatives Chemical class 0.000 description 3
238000002203 pretreatment Methods 0.000 description 3
230000008569 process Effects 0.000 description 3
230000009467 reduction Effects 0.000 description 3
CVHZOJJKTDOEJC-UHFFFAOYSA-N saccharin Chemical compound C1=CC=C2C(=O)NS(=O)(=O)C2=C1 CVHZOJJKTDOEJC-UHFFFAOYSA-N 0.000 description 3
229940081974 saccharin Drugs 0.000 description 3
235000019204 saccharin Nutrition 0.000 description 3
239000000901 saccharin and its Na,K and Ca salt Substances 0.000 description 3
239000003765 sweetening agent Substances 0.000 description 3
LDVVTQMJQSCDMK-UHFFFAOYSA-N 1,3-dihydroxypropan-2-yl formate Chemical compound OCC(CO)OC=O LDVVTQMJQSCDMK-UHFFFAOYSA-N 0.000 description 2
IANQTJSKSUMEQM-UHFFFAOYSA-N 1-benzofuran Chemical compound C1=CC=C2OC=CC2=C1 IANQTJSKSUMEQM-UHFFFAOYSA-N 0.000 description 2
244000060011 Cocos nucifera Species 0.000 description 2
235000013162 Cocos nucifera Nutrition 0.000 description 2
FBPFZTCFMRRESA-FSIIMWSLSA-N D-Glucitol Natural products OC[C@H](O)[C@H](O)[C@@H](O)[C@H](O)CO FBPFZTCFMRRESA-FSIIMWSLSA-N 0.000 description 2
QNAYBMKLOCPYGJ-REOHCLBHSA-N L-alanine Chemical compound C[C@H](N)C(O)=O QNAYBMKLOCPYGJ-REOHCLBHSA-N 0.000 description 2
DAOANAATJZWTSJ-UHFFFAOYSA-N N-Decanoylmorpholine Chemical compound CCCCCCCCCC(=O)N1CCOCC1 DAOANAATJZWTSJ-UHFFFAOYSA-N 0.000 description 2
OAICVXFJPJFONN-UHFFFAOYSA-N Phosphorus Chemical compound [P] OAICVXFJPJFONN-UHFFFAOYSA-N 0.000 description 2
VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 description 2
XSQUKJJJFZCRTK-UHFFFAOYSA-N Urea Chemical compound NC(N)=O XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 description 2
DPXJVFZANSGRMM-UHFFFAOYSA-N acetic acid;2,3,4,5,6-pentahydroxyhexanal;sodium Chemical compound [Na].CC(O)=O.OCC(O)C(O)C(O)C(O)C=O DPXJVFZANSGRMM-UHFFFAOYSA-N 0.000 description 2
235000004279 alanine Nutrition 0.000 description 2
150000001450 anions Chemical class 0.000 description 2
235000019606 astringent taste Nutrition 0.000 description 2
229960003237 betaine Drugs 0.000 description 2
239000007853 buffer solution Substances 0.000 description 2
239000001768 carboxy methyl cellulose Substances 0.000 description 2
238000006243 chemical reaction Methods 0.000 description 2
230000000052 comparative effect Effects 0.000 description 2
239000007859 condensation product Substances 0.000 description 2
XPPKVPWEQAFLFU-UHFFFAOYSA-J diphosphate(4-) Chemical compound [O-]P([O-])(=O)OP([O-])([O-])=O XPPKVPWEQAFLFU-UHFFFAOYSA-J 0.000 description 2
229920001971 elastomer Polymers 0.000 description 2
150000002148 esters Chemical class 0.000 description 2
150000004665 fatty acids Chemical class 0.000 description 2
239000006260 foam Substances 0.000 description 2
150000002431 hydrogen Chemical group 0.000 description 2
SUMDYPCJJOFFON-UHFFFAOYSA-N isethionic acid Chemical compound OCCS(O)(=O)=O SUMDYPCJJOFFON-UHFFFAOYSA-N 0.000 description 2
239000007788 liquid Substances 0.000 description 2
238000004519 manufacturing process Methods 0.000 description 2
229910052751 metal Inorganic materials 0.000 description 2
239000002184 metal Substances 0.000 description 2
238000002156 mixing Methods 0.000 description 2
229910052698 phosphorus Inorganic materials 0.000 description 2
239000011574 phosphorus Substances 0.000 description 2
NROKBHXJSPEDAR-UHFFFAOYSA-M potassium fluoride Chemical compound [F-].[K+] NROKBHXJSPEDAR-UHFFFAOYSA-M 0.000 description 2
230000009257 reactivity Effects 0.000 description 2
FSYKKLYZXJSNPZ-UHFFFAOYSA-N sarcosine Chemical compound C[NH2+]CC([O-])=O FSYKKLYZXJSNPZ-UHFFFAOYSA-N 0.000 description 2
235000019812 sodium carboxymethyl cellulose Nutrition 0.000 description 2
229920001027 sodium carboxymethylcellulose Polymers 0.000 description 2
PUZPDOWCWNUUKD-UHFFFAOYSA-M sodium fluoride Chemical compound [F-].[Na+] PUZPDOWCWNUUKD-UHFFFAOYSA-M 0.000 description 2
239000007787 solid Substances 0.000 description 2
239000000600 sorbitol Substances 0.000 description 2
BDHFUVZGWQCTTF-UHFFFAOYSA-M sulfonate Chemical compound [O-]S(=O)=O BDHFUVZGWQCTTF-UHFFFAOYSA-M 0.000 description 2
235000019640 taste Nutrition 0.000 description 2
KQTIIICEAUMSDG-UHFFFAOYSA-N tricarballylic acid Chemical compound OC(=O)CC(C(O)=O)CC(O)=O KQTIIICEAUMSDG-UHFFFAOYSA-N 0.000 description 2
239000001993 wax Substances 0.000 description 2
BJEPYKJPYRNKOW-REOHCLBHSA-N (S)-malic acid Chemical compound OC(=O)[C@@H](O)CC(O)=O BJEPYKJPYRNKOW-REOHCLBHSA-N 0.000 description 1
SVGVBNWLBIPXII-UHFFFAOYSA-N 2-(2-hydroxyethylamino)ethanol;hydrofluoride Chemical compound [F-].OCC[NH2+]CCO SVGVBNWLBIPXII-UHFFFAOYSA-N 0.000 description 1
JAHNSTQSQJOJLO-UHFFFAOYSA-N 2-(3-fluorophenyl)-1h-imidazole Chemical compound FC1=CC=CC(C=2NC=CN=2)=C1 JAHNSTQSQJOJLO-UHFFFAOYSA-N 0.000 description 1
DNUYOWCKBJFOGS-UHFFFAOYSA-N 2-[[10-(2,2-dicarboxyethyl)anthracen-9-yl]methyl]propanedioic acid Chemical compound C1=CC=C2C(CC(C(=O)O)C(O)=O)=C(C=CC=C3)C3=C(CC(C(O)=O)C(O)=O)C2=C1 DNUYOWCKBJFOGS-UHFFFAOYSA-N 0.000 description 1
SOMFYTZZRTVVDS-UHFFFAOYSA-N 2-phosphonododecan-2-ylphosphonic acid Chemical compound CCCCCCCCCCC(C)(P(=O)(O)O)P(=O)(O)O SOMFYTZZRTVVDS-UHFFFAOYSA-N 0.000 description 1
ROPQINLWRARCTM-UHFFFAOYSA-N 2-phosphonopropan-2-ylphosphonic acid Chemical compound OP(=O)(O)C(C)(C)P(O)(O)=O ROPQINLWRARCTM-UHFFFAOYSA-N 0.000 description 1
DDFHBQSCUXNBSA-UHFFFAOYSA-N 5-(5-carboxythiophen-2-yl)thiophene-2-carboxylic acid Chemical compound S1C(C(=O)O)=CC=C1C1=CC=C(C(O)=O)S1 DDFHBQSCUXNBSA-UHFFFAOYSA-N 0.000 description 1
RBJBFHZUIPIEJX-UHFFFAOYSA-N 5-phosphonononan-5-ylphosphonic acid Chemical compound CCCCC(P(O)(O)=O)(P(O)(O)=O)CCCC RBJBFHZUIPIEJX-UHFFFAOYSA-N 0.000 description 1
VACXNTDDDOYUQP-UHFFFAOYSA-N 8-phosphonopentadecan-8-ylphosphonic acid Chemical compound CCCCCCCC(CCCCCCC)(P(O)(O)=O)P(O)(O)=O VACXNTDDDOYUQP-UHFFFAOYSA-N 0.000 description 1
244000215068 Acacia senegal Species 0.000 description 1
KLZUFWVZNOTSEM-UHFFFAOYSA-K Aluminum fluoride Inorganic materials F[Al](F)F KLZUFWVZNOTSEM-UHFFFAOYSA-K 0.000 description 1
241000416162 Astragalus gummifer Species 0.000 description 1
ZJZOHFDIYSCSPH-UHFFFAOYSA-N C.OP(=O)OP(O)(O)=O Chemical compound C.OP(=O)OP(O)(O)=O ZJZOHFDIYSCSPH-UHFFFAOYSA-N 0.000 description 1
OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 description 1
239000004132 Calcium polyphosphate Substances 0.000 description 1
241000282465 Canis Species 0.000 description 1
239000004215 Carbon black (E152) Substances 0.000 description 1
WMTIOGUVKBSEOW-UHFFFAOYSA-N ClC1(Cl)OP(=O)OP(=O)O1 Chemical compound ClC1(Cl)OP(=O)OP(=O)O1 WMTIOGUVKBSEOW-UHFFFAOYSA-N 0.000 description 1
UDIPTWFVPPPURJ-UHFFFAOYSA-M Cyclamate Chemical compound [Na+].[O-]S(=O)(=O)NC1CCCCC1 UDIPTWFVPPPURJ-UHFFFAOYSA-M 0.000 description 1
FBPFZTCFMRRESA-JGWLITMVSA-N D-glucitol Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-JGWLITMVSA-N 0.000 description 1
RFSUNEUAIZKAJO-ARQDHWQXSA-N Fructose Chemical compound OC[C@H]1O[C@](O)(CO)[C@@H](O)[C@@H]1O RFSUNEUAIZKAJO-ARQDHWQXSA-N 0.000 description 1
WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 1
229920000084 Gum arabic Polymers 0.000 description 1
229920000569 Gum karaya Polymers 0.000 description 1
239000004354 Hydroxyethyl cellulose Substances 0.000 description 1
229920000663 Hydroxyethyl cellulose Polymers 0.000 description 1
235000006679 Mentha X verticillata Nutrition 0.000 description 1
235000002899 Mentha suaveolens Nutrition 0.000 description 1
235000001636 Mentha x rotundifolia Nutrition 0.000 description 1
JYXGIOKAKDAARW-UHFFFAOYSA-N N-(2-hydroxyethyl)iminodiacetic acid Chemical compound OCCN(CC(O)=O)CC(O)=O JYXGIOKAKDAARW-UHFFFAOYSA-N 0.000 description 1
PUYSCNKVHHQOKX-UHFFFAOYSA-M S(=O)(=O)(OCCCCCCCCCCCC)O.[Na+].[F-] Chemical compound S(=O)(=O)(OCCCCCCCCCCCC)O.[Na+].[F-] PUYSCNKVHHQOKX-UHFFFAOYSA-M 0.000 description 1
108010077895 Sarcosine Proteins 0.000 description 1
229920001615 Tragacanth Polymers 0.000 description 1
240000008042 Zea mays Species 0.000 description 1
235000005824 Zea mays ssp. parviglumis Nutrition 0.000 description 1
235000002017 Zea mays subsp mays Nutrition 0.000 description 1
LVOWNHWJMHDSMM-UHFFFAOYSA-J [Sn+4].[O-]P(=O)OP([O-])=O.[O-]P(=O)OP([O-])=O Chemical class [Sn+4].[O-]P(=O)OP([O-])=O.[O-]P(=O)OP([O-])=O LVOWNHWJMHDSMM-UHFFFAOYSA-J 0.000 description 1
WKBWYLXFNPONGU-UHFFFAOYSA-N [bromo(phosphono)methyl]phosphonic acid Chemical compound OP(O)(=O)C(Br)P(O)(O)=O WKBWYLXFNPONGU-UHFFFAOYSA-N 0.000 description 1
235000010489 acacia gum Nutrition 0.000 description 1
239000000205 acacia gum Substances 0.000 description 1
125000001931 aliphatic group Chemical group 0.000 description 1
125000003342 alkenyl group Chemical group 0.000 description 1
150000001350 alkyl halides Chemical class 0.000 description 1
150000008051 alkyl sulfates Chemical class 0.000 description 1
230000002152 alkylating effect Effects 0.000 description 1
BJEPYKJPYRNKOW-UHFFFAOYSA-N alpha-hydroxysuccinic acid Natural products OC(=O)C(O)CC(O)=O BJEPYKJPYRNKOW-UHFFFAOYSA-N 0.000 description 1
SNAAJJQQZSMGQD-UHFFFAOYSA-N aluminum magnesium Chemical compound [Mg].[Al] SNAAJJQQZSMGQD-UHFFFAOYSA-N 0.000 description 1
WMGSQTMJHBYJMQ-UHFFFAOYSA-N aluminum;magnesium;silicate Chemical compound [Mg+2].[Al+3].[O-][Si]([O-])([O-])[O-] WMGSQTMJHBYJMQ-UHFFFAOYSA-N 0.000 description 1
235000001014 amino acid Nutrition 0.000 description 1
150000001413 amino acids Chemical class 0.000 description 1
239000010617 anise oil Substances 0.000 description 1
WQZGKKKJIJFFOK-VFUOTHLCSA-N beta-D-glucose Chemical compound OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-VFUOTHLCSA-N 0.000 description 1
239000011230 binding agent Substances 0.000 description 1
FIVJMCNNMIGYRO-UHFFFAOYSA-N bis(2-hydroxyethyl)-dimethylazanium Chemical compound OCC[N+](C)(C)CCO FIVJMCNNMIGYRO-UHFFFAOYSA-N 0.000 description 1
239000001273 butane Substances 0.000 description 1
239000011575 calcium Substances 0.000 description 1
229910052791 calcium Inorganic materials 0.000 description 1
JUNWLZAGQLJVLR-UHFFFAOYSA-J calcium diphosphate Chemical compound [Ca+2].[Ca+2].[O-]P([O-])(=O)OP([O-])([O-])=O JUNWLZAGQLJVLR-UHFFFAOYSA-J 0.000 description 1
235000019827 calcium polyphosphate Nutrition 0.000 description 1
229940043256 calcium pyrophosphate Drugs 0.000 description 1
239000004202 carbamide Substances 0.000 description 1
229910052799 carbon Inorganic materials 0.000 description 1
150000001721 carbon Chemical group 0.000 description 1
229920003090 carboxymethyl hydroxyethyl cellulose Polymers 0.000 description 1
238000005266 casting Methods 0.000 description 1
229920003086 cellulose ether Polymers 0.000 description 1
238000005119 centrifugation Methods 0.000 description 1
XJHCXCQVJFPJIK-UHFFFAOYSA-M cesium fluoride Substances [F-].[Cs+] XJHCXCQVJFPJIK-UHFFFAOYSA-M 0.000 description 1
230000001055 chewing effect Effects 0.000 description 1
239000012459 cleaning agent Substances 0.000 description 1
238000004040 coloring Methods 0.000 description 1
230000009918 complex formation Effects 0.000 description 1
235000005822 corn Nutrition 0.000 description 1
239000013078 crystal Substances 0.000 description 1
239000000625 cyclamic acid and its Na and Ca salt Substances 0.000 description 1
239000003479 dental cement Substances 0.000 description 1
210000004268 dentin Anatomy 0.000 description 1
230000006866 deterioration Effects 0.000 description 1
230000018109 developmental process Effects 0.000 description 1
239000008121 dextrose Substances 0.000 description 1
235000019821 dicalcium diphosphate Nutrition 0.000 description 1
210000002249 digestive system Anatomy 0.000 description 1
235000011180 diphosphates Nutrition 0.000 description 1
XQRLCLUYWUNEEH-UHFFFAOYSA-N diphosphonic acid Chemical compound OP(=O)OP(O)=O XQRLCLUYWUNEEH-UHFFFAOYSA-N 0.000 description 1
RWSWOANLVTWMDE-UHFFFAOYSA-N dodecylazanium;fluoride Chemical compound F.CCCCCCCCCCCCN RWSWOANLVTWMDE-UHFFFAOYSA-N 0.000 description 1
238000002474 experimental method Methods 0.000 description 1
150000004673 fluoride salts Chemical class 0.000 description 1
238000005187 foaming Methods 0.000 description 1
238000009472 formulation Methods 0.000 description 1
229960002737 fructose Drugs 0.000 description 1
239000011521 glass Substances 0.000 description 1
229960001031 glucose Drugs 0.000 description 1
229930195733 hydrocarbon Natural products 0.000 description 1
235000019447 hydroxyethyl cellulose Nutrition 0.000 description 1
238000011065 in-situ storage Methods 0.000 description 1
239000004615 ingredient Substances 0.000 description 1
229910001506 inorganic fluoride Inorganic materials 0.000 description 1
229940045996 isethionic acid Drugs 0.000 description 1
235000010494 karaya gum Nutrition 0.000 description 1
239000004816 latex Substances 0.000 description 1
229920000126 latex Polymers 0.000 description 1
239000001630 malic acid Substances 0.000 description 1
235000011090 malic acid Nutrition 0.000 description 1
239000001525 mentha piperita l. herb oil Substances 0.000 description 1
IJFXRHURBJZNAO-UHFFFAOYSA-N meta--hydroxybenzoic acid Natural products OC(=O)C1=CC=CC(O)=C1 IJFXRHURBJZNAO-UHFFFAOYSA-N 0.000 description 1
229910021645 metal ion Inorganic materials 0.000 description 1
OSWPMRLSEDHDFF-UHFFFAOYSA-N methyl salicylate Chemical compound COC(=O)C1=CC=CC=C1O OSWPMRLSEDHDFF-UHFFFAOYSA-N 0.000 description 1
LVHBHZANLOWSRM-UHFFFAOYSA-N methylenebutanedioic acid Natural products OC(=O)CC(=C)C(O)=O LVHBHZANLOWSRM-UHFFFAOYSA-N 0.000 description 1
210000000214 mouth Anatomy 0.000 description 1
IJDNQMDRQITEOD-UHFFFAOYSA-N n-butane Chemical compound CCCC IJDNQMDRQITEOD-UHFFFAOYSA-N 0.000 description 1
OFBQJSOFQDEBGM-UHFFFAOYSA-N n-pentane Natural products CCCCC OFBQJSOFQDEBGM-UHFFFAOYSA-N 0.000 description 1
229920001206 natural gum Polymers 0.000 description 1
229910052759 nickel Inorganic materials 0.000 description 1
PXHVJJICTQNCMI-UHFFFAOYSA-N nickel Substances [Ni] PXHVJJICTQNCMI-UHFFFAOYSA-N 0.000 description 1
239000003921 oil Substances 0.000 description 1
235000019198 oils Nutrition 0.000 description 1
FATBGEAMYMYZAF-KTKRTIGZSA-N oleamide Chemical compound CCCCCCCC\C=C/CCCCCCCC(N)=O FATBGEAMYMYZAF-KTKRTIGZSA-N 0.000 description 1
229940113162 oleylamide Drugs 0.000 description 1
239000008375 oral care agent Substances 0.000 description 1
BHZSLLSDZFAPFH-UHFFFAOYSA-L palladium(2+);difluoride Chemical compound F[Pd]F BHZSLLSDZFAPFH-UHFFFAOYSA-L 0.000 description 1
239000012188 paraffin wax Substances 0.000 description 1
XYJRXVWERLGGKC-UHFFFAOYSA-D pentacalcium;hydroxide;triphosphate Chemical compound [OH-].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O XYJRXVWERLGGKC-UHFFFAOYSA-D 0.000 description 1
235000019477 peppermint oil Nutrition 0.000 description 1
NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 description 1
235000003270 potassium fluoride Nutrition 0.000 description 1
239000011698 potassium fluoride Substances 0.000 description 1
KNBZLZHMHWFBSE-UHFFFAOYSA-M potassium;2-aminoacetic acid;fluoride Chemical compound [F-].[K+].NCC(O)=O KNBZLZHMHWFBSE-UHFFFAOYSA-M 0.000 description 1
238000004382 potting Methods 0.000 description 1
239000000843 powder Substances 0.000 description 1
239000002244 precipitate Substances 0.000 description 1
238000004321 preservation Methods 0.000 description 1
230000002265 prevention Effects 0.000 description 1
230000003449 preventive effect Effects 0.000 description 1
210000003296 saliva Anatomy 0.000 description 1
229940043230 sarcosine Drugs 0.000 description 1
239000010672 sassafras oil Substances 0.000 description 1
239000000377 silicon dioxide Substances 0.000 description 1
229940096017 silver fluoride Drugs 0.000 description 1
229960001462 sodium cyclamate Drugs 0.000 description 1
235000013024 sodium fluoride Nutrition 0.000 description 1
239000011775 sodium fluoride Substances 0.000 description 1
AQMNWCRSESPIJM-UHFFFAOYSA-M sodium metaphosphate Chemical compound [Na+].[O-]P(=O)=O AQMNWCRSESPIJM-UHFFFAOYSA-M 0.000 description 1
238000003860 storage Methods 0.000 description 1
239000000126 substance Substances 0.000 description 1
150000005846 sugar alcohols Polymers 0.000 description 1
239000006228 supernatant Substances 0.000 description 1
239000010414 supernatant solution Substances 0.000 description 1
239000006188 syrup Substances 0.000 description 1
235000020357 syrup Nutrition 0.000 description 1
229920001187 thermosetting polymer Polymers 0.000 description 1
150000003606 tin compounds Chemical class 0.000 description 1
229910001432 tin ion Inorganic materials 0.000 description 1
231100000331 toxic Toxicity 0.000 description 1
230000002588 toxic effect Effects 0.000 description 1
235000010487 tragacanth Nutrition 0.000 description 1
239000000196 tragacanth Substances 0.000 description 1
229940116362 tragacanth Drugs 0.000 description 1
239000009637 wintergreen oil Substances 0.000 description 1
229910052726 zirconium Inorganic materials 0.000 description 1
OMQSJNWFFJOIMO-UHFFFAOYSA-J zirconium tetrafluoride Chemical compound F[Zr](F)(F)F OMQSJNWFFJOIMO-UHFFFAOYSA-J 0.000 description 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/55—Phosphorus compounds
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
- C07F9/3804—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)] not used, see subgroups
- C07F9/3839—Polyphosphonic acids

Landscapes

Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Biochemistry (AREA)
Molecular Biology (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Birds (AREA)
Epidemiology (AREA)
Oral & Maxillofacial Surgery (AREA)
Cosmetics (AREA)

CH1824167A 1966-12-29 1967-12-28 Mundpflegemittel CH494034A (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US60561466A	1966-12-29	1966-12-29

Publications (1)

Publication Number	Publication Date
CH494034A true CH494034A (de)	1970-07-31

Family

ID=24424452

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
CH1824167A CH494034A (de)	1966-12-29	1967-12-28	Mundpflegemittel

Country Status (11)

Country	Link
AT (1)	AT279051B (fr)
BE (1)	BE717257A (fr)
CH (1)	CH494034A (fr)
DE (1)	DE1668572B2 (fr)
DK (1)	DK120653B (fr)
FR (4)	FR1565412A (fr)
GB (1)	GB1160640A (fr)
IT (1)	IT1003503B (fr)
NL (1)	NL162834C (fr)
NO (1)	NO125658B (fr)
SE (1)	SE348939B (fr)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPS5846483B2 (ja)	1979-09-20	1983-10-17	ライオン株式会社	口腔用組成物
GB8419489D0 (en) *	1984-07-31	1984-09-05	Leo Pharm Prod Ltd	Chemical compounds
US7404967B2 (en)	1994-12-21	2008-07-29	Cosmederm, Inc.	Topical product formulations containing strontium for reducing skin irritation
MX355533B (es)	2012-12-24	2018-04-20	Colgate Palmolive Co	Composicion para el cuidado oral.
CN115461041A (zh) *	2020-03-11	2022-12-09	艾德凡斯化学公司	用于保健品的表面活性剂

1967
- 1967-12-15 AT AT1135467A patent/AT279051B/de not_active IP Right Cessation
- 1967-12-16 DE DE1668572A patent/DE1668572B2/de active Granted
- 1967-12-27 SE SE17824/67A patent/SE348939B/xx unknown
- 1967-12-27 IT IT41677/67A patent/IT1003503B/it active
- 1967-12-28 NO NO171187A patent/NO125658B/no unknown
- 1967-12-28 CH CH1824167A patent/CH494034A/de not_active IP Right Cessation
- 1967-12-29 GB GB59117/67A patent/GB1160640A/en not_active Expired
- 1967-12-29 DK DK666467AA patent/DK120653B/da unknown
- 1967-12-29 FR FR134224A patent/FR1565412A/fr not_active Expired
- 1967-12-29 FR FR134223A patent/FR7277M/fr not_active Expired
1968
- 1968-06-27 NL NL6809107.A patent/NL162834C/xx not_active IP Right Cessation
- 1968-06-27 BE BE717257A patent/BE717257A/xx not_active IP Right Cessation
- 1968-06-28 FR FR157012A patent/FR289F/fr not_active Expired
- 1968-06-28 FR FR157013A patent/FR95095E/fr not_active Expired

Also Published As

Publication number	Publication date
FR95095E (fr)	1970-06-19
FR1565412A (fr)	1969-05-02
AT279051B (de)	1970-02-25
DE1668572B2 (de)	1975-07-31
FR7277M (fr)	1969-09-22
GB1160640A (en)	1969-08-06
DK120653B (da)	1971-06-28
BE717257A (fr)	1968-12-27
NO125658B (fr)	1972-10-16
DE1668572A1 (de)	1971-09-02
NL162834B (nl)	1980-02-15
FR289F (fr)	1970-01-19
SE348939B (fr)	1972-09-18
NL6809107A (fr)	1969-12-30
NL162834C (nl)	1980-07-15
IT1003503B (it)	1976-06-10

Legal Events

Date	Code	Title	Description
1973-07-31	PL	Patent ceased

Publication	Publication Date	Title
CH649706A5 (de)	1985-06-14	Mund- und zahnpflegemittel.
DE1617729B2 (de)	1973-09-13	Zahnsteinbildung verhinderndes Mund- und Zahnpflegemittel
DE1033856B (de)	1958-07-10	Zahnpflegemittel
AT390731B (de)	1990-06-25	Zahncreme
DE1908067B2 (de)	1977-08-11	Zusammensetzungen zur verhinderung von zahnsteinbildung
NO171187B (no)	1992-10-26	Anordning for forsterkning og sampling av multiplekserte signaler
CH494034A (de)	1970-07-31	Mundpflegemittel
DE1492027B2 (de)	1977-03-10	Natriummonofluorphosphat enthaltende zahnpaste
DE2255177C3 (de)	1982-02-18	Mittel zur Verhinderung von Zahnstein
US3937806A (en)	1976-02-10	Oral compositions for caries prophylaxis
DE3402805A1 (de)	1984-12-13	Gegen karies und zahnstein wirkendes mundpflegemittel
US3544678A (en)	1970-12-01	Oral compositions for caries prophylaxis
DE2310771B2 (de)	1977-02-24	Die zahnsteinbildung hemmende zusammensetzung mit einem silikaxerogel- abriebstoff
DE2953295C2 (fr)	1988-11-24
US3448132A (en)	1969-06-03	Stannous hydroxyethylnitrilodiacetate
US3560608A (en)	1971-02-02	Oral compositions for caries and calculus prophylaxis
US3266996A (en)	1966-08-16	Oral compositions for caries prophylaxis containing stannous fluorozirconate
DE2153821B2 (de)	1978-10-19	Zahnpflegemittel
DE1668572C3 (de)	1976-03-11	Dizinn-(ll)-salze von Gem.-Diphosphonsäuren
US3440004A (en)	1969-04-22	Indium fluorozirconate,inzrf7
DE2202142A1 (de)	1972-07-27	Difluoroxalatostannat(II)-Komplexe
DE1960068C3 (de)	1982-05-13	Zahnpasta mit antikariogener Wirksamkeit
DE2456692A1 (de)	1976-08-12	Verfahren zum stabilisieren von calciumhydrogenphosphat-dihydrat gegen hydrolyse
AT275043B (de)	1969-10-10	Zahnsteinbildung verhinderndes Mund- und Zahnpflegemittel
US3546335A (en)	1970-12-08	Compositions for caries prophylaxis containing indium fluorogermanate in2(gef6)3