CH634589A5 - Process for the preparation of an aqueous dispersion or solution of a protein bonded to a urethane polymer - Google Patents

Process for the preparation of an aqueous dispersion or solution of a protein bonded to a urethane polymer Download PDF

Info

Publication number: CH634589A5
Authority: CH; Switzerland
Prior art keywords: protein; prepolymer; bound; water; polymer
Prior art date: 1976-12-10

Application number

CH1515877A

Other languages

German (de)

English (en)

Inventor

Frank Joseph Hartdegen

Wayne Elliott Swann

Original Assignee

Grace W R & Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1976-12-10

Filing date

1977-12-09

Publication date

1983-02-15

1976-12-10 Priority claimed from US05/749,430 external-priority patent/US4094744A/en

1977-12-09 Application filed by Grace W R & Co filed Critical Grace W R & Co

1983-02-15 Publication of CH634589A5 publication Critical patent/CH634589A5/de

Links

102000004169 proteins and genes Human genes 0.000 title claims description 79
108090000623 proteins and genes Proteins 0.000 title claims description 79
229920000642 polymer Polymers 0.000 title claims description 40
238000000034 method Methods 0.000 title claims description 24
239000006185 dispersion Substances 0.000 title claims description 23
JOYRKODLDBILNP-UHFFFAOYSA-N urethane group Chemical group NC(=O)OCC JOYRKODLDBILNP-UHFFFAOYSA-N 0.000 title claims description 7
238000002360 preparation method Methods 0.000 title claims description 4
XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 43
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IQPQWNKOIGAROB-UHFFFAOYSA-N isocyanate group Chemical group [N-]=C=O IQPQWNKOIGAROB-UHFFFAOYSA-N 0.000 claims description 27
239000007788 liquid Substances 0.000 claims description 26
229920005862 polyol Polymers 0.000 claims description 25
239000004814 polyurethane Substances 0.000 claims description 25
-1 oxyethylene, oxypropylene Chemical group 0.000 claims description 24
229920002635 polyurethane Polymers 0.000 claims description 24
150000003077 polyols Chemical class 0.000 claims description 23
229920001730 Moisture cure polyurethane Polymers 0.000 claims description 19
239000000047 product Substances 0.000 claims description 14
238000006243 chemical reaction Methods 0.000 claims description 12
239000000203 mixture Substances 0.000 claims description 11
239000007795 chemical reaction product Substances 0.000 claims description 9
125000006353 oxyethylene group Chemical group 0.000 claims description 7
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Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y305/00—Hydrolases acting on carbon-nitrogen bonds, other than peptide bonds (3.5)
- C12Y305/01—Hydrolases acting on carbon-nitrogen bonds, other than peptide bonds (3.5) in linear amides (3.5.1)
- C12Y305/01011—Penicillin amidase (3.5.1.11), i.e. penicillin-amidohydrolase
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N11/00—Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
- C12N11/02—Enzymes or microbial cells immobilised on or in an organic carrier
- C12N11/08—Enzymes or microbial cells immobilised on or in an organic carrier the carrier being a synthetic polymer
- C12N11/089—Enzymes or microbial cells immobilised on or in an organic carrier the carrier being a synthetic polymer obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
- C12N11/093—Polyurethanes
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/38—Albumins
- A61K38/385—Serum albumin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
- A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
- A61K38/482—Serine endopeptidases (3.4.21)
- A61K38/4826—Trypsin (3.4.21.4) Chymotrypsin (3.4.21.1)
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G18/00—Polymeric products of isocyanates or isothiocyanates
- C08G18/06—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen
- C08G18/28—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen characterised by the compounds used containing active hydrogen
- C08G18/40—High-molecular-weight compounds
- C08G18/64—Macromolecular compounds not provided for by groups C08G18/42 - C08G18/63
- C08G18/6415—Macromolecular compounds not provided for by groups C08G18/42 - C08G18/63 having nitrogen
- C08G18/6446—Proteins and derivatives thereof
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
- C12Y304/21—Serine endopeptidases (3.4.21)
- C12Y304/21004—Trypsin (3.4.21.4)

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Zoology (AREA)
Genetics & Genomics (AREA)
General Health & Medical Sciences (AREA)
Wood Science & Technology (AREA)
General Engineering & Computer Science (AREA)
Biochemistry (AREA)
Medicinal Chemistry (AREA)
Veterinary Medicine (AREA)
Animal Behavior & Ethology (AREA)
Microbiology (AREA)
Epidemiology (AREA)
Public Health (AREA)
Gastroenterology & Hepatology (AREA)
Immunology (AREA)
Pharmacology & Pharmacy (AREA)
Biotechnology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Biomedical Technology (AREA)
Polymers & Plastics (AREA)
Chemical Kinetics & Catalysis (AREA)
Mycology (AREA)
Polyurethanes Or Polyureas (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Peptides Or Proteins (AREA)
Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
Processes Of Treating Macromolecular Substances (AREA)

CH1515877A 1976-12-10 1977-12-09 Process for the preparation of an aqueous dispersion or solution of a protein bonded to a urethane polymer CH634589A5 (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US05/749,430 US4094744A (en)	1976-11-18	1976-12-10	Water-dispersible protein/polyurethane reaction product

Publications (1)

Publication Number	Publication Date
CH634589A5 true CH634589A5 (en)	1983-02-15

Family

ID=25013731

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
CH1515877A CH634589A5 (en)	1976-12-10	1977-12-09	Process for the preparation of an aqueous dispersion or solution of a protein bonded to a urethane polymer

Country Status (9)

Country	Link
JP (1)	JPS5379094A (fr)
AT (1)	AT356620B (fr)
BE (1)	BE861602A (fr)
CH (1)	CH634589A5 (fr)
DE (1)	DE2755053A1 (fr)
FR (1)	FR2393005B1 (fr)
GB (1)	GB1574508A (fr)
MX (1)	MX4534E (fr)
NL (1)	NL187585C (fr)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4226935A (en) *	1978-08-07	1980-10-07	W. R. Grace & Co.	Enzymatic diagnostic composition
US4652524A (en) *	1980-10-02	1987-03-24	Ivan E. Modrovich	Soluble stabilized enzymes
US4732851A (en) *	1982-03-16	1988-03-22	Purification Engineering, Inc.	Immobilization of cells with a polyazetidine prepolymer
DE3705687A1 (de) *	1987-02-23	1988-09-01	Boehringer Mannheim Gmbh	Polyurethanmodifizierte enzyme
US6905733B2 (en)	2001-07-24	2005-06-14	University Of Pittsburgh	Irreversible immobilization of enzymes into polyurethane coatings
US7335400B2 (en) *	2001-07-24	2008-02-26	University Of Pittsburgh	Irreversible immobilization of enzymes into polyurethane coatings
US9121016B2 (en) *	2011-09-09	2015-09-01	Toyota Motor Engineering & Manufacturing North America, Inc.	Coatings containing polymer modified enzyme for stable self-cleaning of organic stains

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3672955A (en) *	1970-05-20	1972-06-27	Us Agriculture	Preparation of an insoluble active enzyme
US3929574A (en) *	1972-05-03	1975-12-30	Grace W R & Co	Use of enzymes bound to polyurethane

1977
- 1977-12-07 DE DE19772755053 patent/DE2755053A1/de active Granted
- 1977-12-07 BE BE183252A patent/BE861602A/fr not_active IP Right Cessation
- 1977-12-08 FR FR7737083A patent/FR2393005B1/fr not_active Expired
- 1977-12-08 GB GB51208/77A patent/GB1574508A/en not_active Expired
- 1977-12-08 NL NLAANVRAGE7713584,A patent/NL187585C/xx not_active IP Right Cessation
- 1977-12-09 CH CH1515877A patent/CH634589A5/de not_active IP Right Cessation
- 1977-12-09 JP JP14728177A patent/JPS5379094A/ja active Granted
- 1977-12-09 MX MX776679U patent/MX4534E/es unknown
- 1977-12-09 AT AT883577A patent/AT356620B/de not_active IP Right Cessation

Also Published As

Publication number	Publication date
JPH0233356B2 (fr)	1990-07-26
MX4534E (es)	1982-06-03
FR2393005A1 (fr)	1978-12-29
DE2755053C2 (fr)	1989-11-09
NL187585B (nl)	1991-06-17
JPS5379094A (en)	1978-07-13
BE861602A (fr)	1978-03-31
NL7713584A (nl)	1978-06-13
DE2755053A1 (de)	1978-06-22
AT356620B (de)	1980-05-12
NL187585C (nl)	1991-11-18
ATA883577A (de)	1979-10-15
FR2393005B1 (fr)	1982-11-12
GB1574508A (en)	1980-09-10

Legal Events

Date	Code	Title	Description
1988-12-30	PFA	Name/firm changed	Owner name: W. R. GRACE & CO.-CONN. (A CONNECTICUT CORP.)
1994-08-31	PL	Patent ceased
2024-10-31	PL	Patent ceased

Publication	Publication Date	Title
DE2365854C2 (de)	1982-04-15	Katalysator für biochemische Umsetzungen
EP0008100B1 (fr)	1982-05-05	Procédé de fabrication d'un support polymère macroporeux pour la fixation covalente de protéines
US4094744A (en)	1978-06-13	Water-dispersible protein/polyurethane reaction product
US4098645A (en)	1978-07-04	Immobilization of proteins with polyurethane polymers
US4195127A (en)	1980-03-25	Process for immobilizing proteins
EP2163617B1 (fr)	2012-03-21	Préparations d'enzymes
EP2011865B1 (fr)	2009-08-12	Préparations d'enzymes
DE2625544C2 (de)	1986-09-11	Verfahren zur Immobilisierung eines biologischen Materials und Zusammensetzung zur Durchführung des Verfahrens
EP0562371B1 (fr)	1997-12-17	Immobilisation de substances biochimiques
DE2755053C2 (fr)	1989-11-09
EP1091996B1 (fr)	2004-12-22	Procede de production d'un biocatalyseur avec un gel a base d'alcool polyvinylique et biocatalyseur obtenu a l'aide dudit procede
DE2612138C2 (de)	1986-09-11	Verfahren zur Herstellung von gebundenes Protein enthaltendem Polyurethanschaum
DE2315508C2 (fr)	1987-07-16
DE2930319A1 (de)	1980-02-28	Diagnostische zusammensetzung, verfahren zu ihrer herstellung und ihre verwendung
EP0222289B1 (fr)	1992-06-17	Procédé d'immobilisation d'une matière biologique, coagulats particulaires contenant une matière biologique immobilisée et leur application comme catalyseur
EP0280212B1 (fr)	1991-05-29	Enzyme modifiée par du polyuréthane
DE2413137A1 (de)	1975-10-16	Enzymatisch aktiver schaumstoff und verfahren zu seiner herstellung
AT343085B (de)	1978-05-10	Katalysator fur biochemische reaktionen und verfahren zu seiner herstellung
DE3134892A1 (de)	1982-05-27	"hydrophiler immobilisierte mikroorganismen enthaltender plyetherpolyurethanschaum, verfahren zur herstellung dieses schaums und seine anwendung zur herstellung von l-alanin"
CH624715A5 (en)	1981-08-14	Catalyst system for biochemical reactions and process for its preparation
EP0277473B1 (fr)	1995-04-12	Compositions polymères réversibles, solubles dans l'eau, leur préparation et leur application à la catalyse homogène
CA1108072A (fr)	1981-09-01	Proteines dispersables dans l'eau, modifiees par des polyurethannes
DE3134891A1 (de)	1982-05-27	"hydrophiler immobilisierte mikroorganismen enthaltender polyetherpolyurethanschaum, verfahren zur herstellung dieses schaums und seine anwendung zur herstellung von l-aminosaeuren aus entsprechenden substraten"
Nelböck et al.	1975	Immobilisierte Enzyme und Prinzipien für ihre Anwendung bei analytischen und präparativen Verfahren
DD158040A1 (de)	1982-12-22	Verfahren zur stoffwandlung durch immobile biokatalysatoren