CH636013A5 - More readily absorbable pharmaceutical composition - Google Patents

More readily absorbable pharmaceutical composition Download PDF

Info

Publication number: CH636013A5
Authority: CH; Switzerland
Prior art keywords: antibiotic; optionally; transesterified; ethanol; drinking
Prior art date: 1978-03-07

Application number

CH246178A

Other languages

German (de)

English (en)

Inventor

Thomas Dr Cavanak

Original Assignee

Sandoz Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1978-03-07

Filing date

1978-03-07

Publication date

1983-05-13

1978-03-07 Application filed by Sandoz Ag filed Critical Sandoz Ag

1978-03-07 Priority to CH246178A priority Critical patent/CH636013A5/de

1979-02-26 Priority to DE19792907460 priority patent/DE2907460A1/de

1979-02-26 Priority to SE7901683A priority patent/SE445174B/sv

1979-02-26 Priority to FI790640A priority patent/FI65914C/fi

1979-02-27 Priority to FR7904989A priority patent/FR2419072A1/fr

1979-02-27 Priority to IT48152/79A priority patent/IT1115038B/it

1979-02-27 Priority to NO790661A priority patent/NO152635C/no

1979-02-28 Priority to DK086079A priority patent/DK154539C/da

1979-03-02 Priority to CY1285A priority patent/CY1285A/en

1979-03-02 Priority to NLAANVRAGE7901703,A priority patent/NL187260C/xx

1979-03-02 Priority to GB7907395A priority patent/GB2015339B/en

1979-03-05 Priority to PT69309A priority patent/PT69309A/fr

1979-03-05 Priority to ES478295A priority patent/ES478295A1/es

1979-03-05 Priority to BE0/193849A priority patent/BE874628A/fr

1979-03-05 Priority to IL56790A priority patent/IL56790A/xx

1979-03-05 Priority to NZ189819A priority patent/NZ189819A/en

1979-03-05 Priority to AT0163779A priority patent/AT375828B/de

1979-03-05 Priority to HU79SA3166A priority patent/HU182920B/hu

1979-03-06 Priority to DD79211409A priority patent/DD142149A5/de

1979-03-06 Priority to AU44862/79A priority patent/AU528714B2/en

1979-03-06 Priority to PH22254A priority patent/PH15159A/en

1979-03-06 Priority to CA000322853A priority patent/CA1139667A/fr

1979-03-07 Priority to ZA791056A priority patent/ZA791056B/xx

1979-03-07 Priority to JP2722879A priority patent/JPS54132223A/ja

1979-03-07 Priority to AR275732A priority patent/AR223667A1/es

1979-08-08 Priority to IE704/79A priority patent/IE48016B1/en

1982-02-09 Priority to US06/347,276 priority patent/US4388307A/en

1983-05-13 Publication of CH636013A5 publication Critical patent/CH636013A5/de

1985-02-27 Priority to SG147/85A priority patent/SG14785G/en

1985-03-22 Priority to KE3516A priority patent/KE3516A/xx

1985-06-20 Priority to HK485/85A priority patent/HK48585A/xx

1985-12-30 Priority to MY134/85A priority patent/MY8500134A/xx

1993-07-02 Priority to NL930135C priority patent/NL930135I1/nl

1994-12-28 Priority to NO1994028C priority patent/NO1994028I1/no

Links

239000008194 pharmaceutical composition Substances 0.000 title description 3
239000000203 mixture Substances 0.000 claims abstract description 44
230000003115 biocidal effect Effects 0.000 claims abstract description 37
239000000243 solution Substances 0.000 claims abstract description 30
LVGKNOAMLMIIKO-UHFFFAOYSA-N Elaidinsaeure-aethylester Natural products CCCCCCCCC=CCCCCCCCC(=O)OCC LVGKNOAMLMIIKO-UHFFFAOYSA-N 0.000 claims abstract description 11
LVGKNOAMLMIIKO-QXMHVHEDSA-N ethyl oleate Chemical compound CCCCCCCC\C=C/CCCCCCCC(=O)OCC LVGKNOAMLMIIKO-QXMHVHEDSA-N 0.000 claims abstract description 11
229940093471 ethyl oleate Drugs 0.000 claims abstract description 11
239000008159 sesame oil Substances 0.000 claims abstract description 11
235000011803 sesame oil Nutrition 0.000 claims abstract description 11
150000003626 triacylglycerols Chemical class 0.000 claims abstract description 11
239000003921 oil Substances 0.000 claims abstract description 9
235000019198 oils Nutrition 0.000 claims abstract description 9
239000000839 emulsion Substances 0.000 claims abstract description 8
239000000787 lecithin Substances 0.000 claims abstract description 8
235000010445 lecithin Nutrition 0.000 claims abstract description 8
230000007935 neutral effect Effects 0.000 claims abstract description 8
238000002347 injection Methods 0.000 claims abstract description 6
239000007924 injection Substances 0.000 claims abstract description 6
239000002736 nonionic surfactant Substances 0.000 claims abstract description 4
150000001875 compounds Chemical class 0.000 claims abstract description 3
LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 45
230000035622 drinking Effects 0.000 claims description 14
239000000654 additive Substances 0.000 claims description 11
OIQOAYVCKAHSEJ-UHFFFAOYSA-N 2-[2,3-bis(2-hydroxyethoxy)propoxy]ethanol;hexadecanoic acid;octadecanoic acid Chemical compound OCCOCC(OCCO)COCCO.CCCCCCCCCCCCCCCC(O)=O.CCCCCCCCCCCCCCCCCC(O)=O OIQOAYVCKAHSEJ-UHFFFAOYSA-N 0.000 claims description 6
239000004094 surface-active agent Substances 0.000 claims description 5
238000010521 absorption reaction Methods 0.000 claims description 4
XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 4
235000010469 Glycine max Nutrition 0.000 claims description 3
150000003904 phospholipids Chemical class 0.000 claims description 3
239000003549 soybean oil Substances 0.000 claims description 3
235000012424 soybean oil Nutrition 0.000 claims description 3
UFTFJSFQGQCHQW-UHFFFAOYSA-N triformin Chemical compound O=COCC(OC=O)COC=O UFTFJSFQGQCHQW-UHFFFAOYSA-N 0.000 claims description 3
IIZPXYDJLKNOIY-JXPKJXOSSA-N 1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphocholine Chemical compound CCCCCCCCCCCCCCCC(=O)OC[C@H](COP([O-])(=O)OCC[N+](C)(C)C)OC(=O)CCC\C=C/C\C=C/C\C=C/C\C=C/CCCCC IIZPXYDJLKNOIY-JXPKJXOSSA-N 0.000 claims description 2
239000003795 chemical substances by application Substances 0.000 claims description 2
229940067606 lecithin Drugs 0.000 claims description 2
238000004519 manufacturing process Methods 0.000 claims description 2
235000013361 beverage Nutrition 0.000 abstract 2
238000003756 stirring Methods 0.000 description 6
238000007918 intramuscular administration Methods 0.000 description 5
238000007920 subcutaneous administration Methods 0.000 description 5
PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 3
IQFYYKKMVGJFEH-XLPZGREQSA-N Thymidine Chemical compound O=C1NC(=O)C(C)=CN1[C@@H]1O[C@H](CO)[C@@H](O)C1 IQFYYKKMVGJFEH-XLPZGREQSA-N 0.000 description 3
239000008389 polyethoxylated castor oil Substances 0.000 description 3
-1 polyoxyethylene Polymers 0.000 description 3
235000010482 polyoxyethylene sorbitan monooleate Nutrition 0.000 description 3
229920000053 polysorbate 80 Polymers 0.000 description 3
239000003755 preservative agent Substances 0.000 description 3
210000002966 serum Anatomy 0.000 description 3
229920002685 Polyoxyl 35CastorOil Polymers 0.000 description 2
SESFRYSPDFLNCH-UHFFFAOYSA-N benzyl benzoate Chemical compound C=1C=CC=CC=1C(=O)OCC1=CC=CC=C1 SESFRYSPDFLNCH-UHFFFAOYSA-N 0.000 description 2
150000004665 fatty acids Chemical group 0.000 description 2
210000004698 lymphocyte Anatomy 0.000 description 2
239000000463 material Substances 0.000 description 2
LXCFILQKKLGQFO-UHFFFAOYSA-N methylparaben Chemical compound COC(=O)C1=CC=C(O)C=C1 LXCFILQKKLGQFO-UHFFFAOYSA-N 0.000 description 2
QUANRIQJNFHVEU-UHFFFAOYSA-N oxirane;propane-1,2,3-triol Chemical compound C1CO1.OCC(O)CO QUANRIQJNFHVEU-UHFFFAOYSA-N 0.000 description 2
238000007911 parenteral administration Methods 0.000 description 2
230000035755 proliferation Effects 0.000 description 2
QELSKZZBTMNZEB-UHFFFAOYSA-N propylparaben Chemical compound CCCOC(=O)C1=CC=C(O)C=C1 QELSKZZBTMNZEB-UHFFFAOYSA-N 0.000 description 2
229920006395 saturated elastomer Polymers 0.000 description 2
235000013311 vegetables Nutrition 0.000 description 2
PUPZLCDOIYMWBV-UHFFFAOYSA-N (+/-)-1,3-Butanediol Chemical compound CC(O)CCO PUPZLCDOIYMWBV-UHFFFAOYSA-N 0.000 description 1
XLMXUUQMSMKFMH-UZRURVBFSA-N 2-hydroxyethyl (z,12r)-12-hydroxyoctadec-9-enoate Chemical compound CCCCCC[C@@H](O)C\C=C/CCCCCCCC(=O)OCCO XLMXUUQMSMKFMH-UZRURVBFSA-N 0.000 description 1
235000019489 Almond oil Nutrition 0.000 description 1
DWRXFEITVBNRMK-UHFFFAOYSA-N Beta-D-1-Arabinofuranosylthymine Natural products O=C1NC(=O)C(C)=CN1C1C(O)C(O)C(CO)O1 DWRXFEITVBNRMK-UHFFFAOYSA-N 0.000 description 1
108010062580 Concanavalin A Proteins 0.000 description 1
235000019482 Palm oil Nutrition 0.000 description 1
235000019483 Peanut oil Nutrition 0.000 description 1
229920003171 Poly (ethylene oxide) Polymers 0.000 description 1
239000002202 Polyethylene glycol Substances 0.000 description 1
WERKSKAQRVDLDW-ANOHMWSOSA-N [(2s,3r,4r,5r)-2,3,4,5,6-pentahydroxyhexyl] (z)-octadec-9-enoate Chemical compound CCCCCCCC\C=C/CCCCCCCC(=O)OC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO WERKSKAQRVDLDW-ANOHMWSOSA-N 0.000 description 1
239000008168 almond oil Substances 0.000 description 1
239000007864 aqueous solution Substances 0.000 description 1
IQFYYKKMVGJFEH-UHFFFAOYSA-N beta-L-thymidine Natural products O=C1NC(=O)C(C)=CN1C1OC(CO)C(O)C1 IQFYYKKMVGJFEH-UHFFFAOYSA-N 0.000 description 1
210000004369 blood Anatomy 0.000 description 1
239000008280 blood Substances 0.000 description 1
IAQRGUVFOMOMEM-UHFFFAOYSA-N butene Natural products CC=CC IAQRGUVFOMOMEM-UHFFFAOYSA-N 0.000 description 1
239000004359 castor oil Substances 0.000 description 1
235000019438 castor oil Nutrition 0.000 description 1
239000006285 cell suspension Substances 0.000 description 1
230000001419 dependent effect Effects 0.000 description 1
235000014113 dietary fatty acids Nutrition 0.000 description 1
229930195729 fatty acid Natural products 0.000 description 1
239000000194 fatty acid Substances 0.000 description 1
125000005456 glyceride group Chemical group 0.000 description 1
ZEMPKEQAKRGZGQ-XOQCFJPHSA-N glycerol triricinoleate Natural products CCCCCC[C@@H](O)CC=CCCCCCCCC(=O)OC[C@@H](COC(=O)CCCCCCCC=CC[C@@H](O)CCCCCC)OC(=O)CCCCCCCC=CC[C@H](O)CCCCCC ZEMPKEQAKRGZGQ-XOQCFJPHSA-N 0.000 description 1
239000012456 homogeneous solution Substances 0.000 description 1
238000000338 in vitro Methods 0.000 description 1
238000010348 incorporation Methods 0.000 description 1
239000012442 inert solvent Substances 0.000 description 1
238000000034 method Methods 0.000 description 1
229960002216 methylparaben Drugs 0.000 description 1
230000006213 negative regulation of lymphocyte proliferation Effects 0.000 description 1
239000004006 olive oil Substances 0.000 description 1
235000008390 olive oil Nutrition 0.000 description 1
239000002540 palm oil Substances 0.000 description 1
239000000312 peanut oil Substances 0.000 description 1
229920001223 polyethylene glycol Polymers 0.000 description 1
239000000244 polyoxyethylene sorbitan monooleate Substances 0.000 description 1
238000002360 preparation method Methods 0.000 description 1
230000002335 preservative effect Effects 0.000 description 1
239000002904 solvent Substances 0.000 description 1
210000004989 spleen cell Anatomy 0.000 description 1
239000000126 substance Substances 0.000 description 1
229940104230 thymidine Drugs 0.000 description 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
- A61K9/1274—Non-vesicle bilayer structures, e.g. liquid crystals, tubules, cubic phases or cochleates; Sponge phases
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
- A61K38/13—Cyclosporins
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4858—Organic compounds

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Engineering & Computer Science (AREA)
Gastroenterology & Hepatology (AREA)
Dermatology (AREA)
Dispersion Chemistry (AREA)
Bioinformatics & Cheminformatics (AREA)
Immunology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Oil, Petroleum & Natural Gas (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

CH246178A 1978-03-07 1978-03-07 More readily absorbable pharmaceutical composition CH636013A5 (en)

Priority Applications (33)

Application Number	Priority Date	Filing Date	Title
CH246178A CH636013A5 (en)	1978-03-07	1978-03-07	More readily absorbable pharmaceutical composition
DE19792907460 DE2907460A1 (de)	1978-03-07	1979-02-26	Neue resorbierbare galenische kompositionen
SE7901683A SE445174B (sv)	1978-03-07	1979-02-26	Farmaceutisk komposition innehallande en cyklosporin och en berarsubstans
FI790640A FI65914C (fi)	1978-03-07	1979-02-26	Foerfarande foer framstaellning av farmaceutiska kompositionerinnehaollande cyklosporin a
FR7904989A FR2419072A1 (fr)	1978-03-07	1979-02-27	Nouvelles compositions pharmaceutiques a base d'un peptide monocyclique
IT48152/79A IT1115038B (it)	1978-03-07	1979-02-27	Composizioni farmaceutiche a base d'un peptide monociclico
NO790661A NO152635C (no)	1978-03-07	1979-02-27	Fremgangsmaate for fremstilling av cyklosporinholdige farmasoeytiske preparater i flytende form
DK086079A DK154539C (da)	1978-03-07	1979-02-28	Fremgangsmaade til fremstilling af cyclosporinholdige farmaceutiske praeparater i flydende form
CY1285A CY1285A (en)	1978-03-07	1979-03-02	Compositions comprising mono-cyclic peptides
NLAANVRAGE7901703,A NL187260C (nl)	1978-03-07	1979-03-02	Werkwijze voor het bereiden of vervaardigen van een farmaceutisch preparaat dat een cyclosporine en een drager bevat.
GB7907395A GB2015339B (en)	1978-03-07	1979-03-02	Compositions comprising mono-cyclic peptides
NZ189819A NZ189819A (en)	1978-03-07	1979-03-05	Pharmaceutical composition: cyclosporin and glyceride-type carrier
ES478295A ES478295A1 (es)	1978-03-07	1979-03-05	Procedimiento para preparar una composicion farmaceutica con propiedades de almacenamiento y absorcion mejoradas.
BE0/193849A BE874628A (fr)	1978-03-07	1979-03-05	Nouvelles compositions pharmaceutiques a base de peptide monocyclique
IL56790A IL56790A (en)	1978-03-07	1979-03-05	Pharmaceutical compositions containing monocyclic peptides
PT69309A PT69309A (fr)	1978-03-07	1979-03-05	Procede pour la production de compositions galeniques
AT0163779A AT375828B (de)	1978-03-07	1979-03-05	Verfahren zur herstellung von neuen resorbierbaren galenischen kompositionen
HU79SA3166A HU182920B (en)	1978-03-07	1979-03-05	Process for preparing stable pharmaceutical compositions containing cyclosporin
DD79211409A DD142149A5 (de)	1978-03-07	1979-03-06	Verfahren zur herstellung resorbierbarer galenischer kompositionen
AU44862/79A AU528714B2 (en)	1978-03-07	1979-03-06	Monocyclic peptide medicine in glyceride carrier
PH22254A PH15159A (en)	1978-03-07	1979-03-06	New galenical composition
CA000322853A CA1139667A (fr)	1978-03-07	1979-03-06	Substances galeniques
ZA791056A ZA791056B (en)	1978-03-07	1979-03-07	New galenical compositions
JP2722879A JPS54132223A (en)	1978-03-07	1979-03-07	Novel pharmaceutical composition
AR275732A AR223667A1 (es)	1978-03-07	1979-03-07	Procedimiento para preparar una composicion farmaceutica,con propiedades de almacenamiento y absorcion mejoradas
IE704/79A IE48016B1 (en)	1978-03-07	1979-08-08	New galenical compositions containing cyclosporins
US06/347,276 US4388307A (en)	1978-03-07	1982-02-09	Galenical compositions
SG147/85A SG14785G (en)	1978-03-07	1985-02-27	New galenical compositions containing cyclosporins
KE3516A KE3516A (en)	1978-03-07	1985-03-22	New galenical compositions containing cyclosporins
HK485/85A HK48585A (en)	1978-03-07	1985-06-20	New galenical compositions containing cyclosporins
MY134/85A MY8500134A (en)	1978-03-07	1985-12-30	New galenical compositions containing cyclosporins
NL930135C NL930135I1 (nl)	1978-03-07	1993-07-02	Werkwijze voor het bereiden of vervaardigen van een farmaceutisch preparaat dat een cyclosporine en een drager bevat
NO1994028C NO1994028I1 (no)	1978-03-07	1994-12-28	Cyklosporin A

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
CH246178A CH636013A5 (en)	1978-03-07	1978-03-07	More readily absorbable pharmaceutical composition

Publications (1)

Publication Number	Publication Date
CH636013A5 true CH636013A5 (en)	1983-05-13

Family

ID=4234340

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
CH246178A CH636013A5 (en)	1978-03-07	1978-03-07	More readily absorbable pharmaceutical composition

Country Status (4)

Country	Link
BE (1)	BE874628A (fr)
CH (1)	CH636013A5 (fr)
HU (1)	HU182920B (fr)
ZA (1)	ZA791056B (fr)

Cited By (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5670478A (en) *	1992-09-07	1997-09-23	Galena, A.S.	Pharmaceutical containing N-methylated cyclic undecapeptides
US5759997A (en) *	1984-07-24	1998-06-02	Novartis Ag	Cyclosporin galenic forms
US5866159A (en) *	1988-09-16	1999-02-02	Novartis Ag	Pharmaceutical compositions comprising cyclosporins
US6007840A (en) *	1988-09-16	1999-12-28	Novartis Ag	Pharmaceutical compositions comprising cyclosporins
US6258808B1 (en)	1991-06-27	2001-07-10	Novartis Ag	Pharmaceutical composition
US6420355B2 (en)	1992-09-25	2002-07-16	Novartis Ag	Pharmaceutical compositions containing cyclosporins
US6486124B2 (en)	1994-11-03	2002-11-26	Novartis Ag	Cyclosporin compositions and process therefor
US6582718B2 (en)	1992-05-13	2003-06-24	Novartis Ag	Cyclosporin compositions
US7081445B2 (en)	1989-02-20	2006-07-25	Novartis Ag	Cyclosporin galenic forms
WO2007047596A1 (fr) *	2005-10-17	2007-04-26	Hill's Pet Nutrition, Inc.	Méthode de réduction de l'absorption d'aliments et de diminution de l'appétit chez les animaux
EP1676488A3 (fr) *	2000-06-26	2013-02-20	The Procter & Gamble Company	Compositions et procédés de régulation du poids corporel

1978
- 1978-03-07 CH CH246178A patent/CH636013A5/de not_active IP Right Cessation
1979
- 1979-03-05 HU HU79SA3166A patent/HU182920B/hu unknown
- 1979-03-05 BE BE0/193849A patent/BE874628A/fr not_active IP Right Cessation
- 1979-03-07 ZA ZA791056A patent/ZA791056B/xx unknown

Cited By (20)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6306825B1 (en)	1984-07-24	2001-10-23	Novartis Ag	Cyclosporin galenic forms
US5759997A (en) *	1984-07-24	1998-06-02	Novartis Ag	Cyclosporin galenic forms
US5977066A (en) *	1984-07-24	1999-11-02	Novartis Ag	Cyclosporin galenic forms
US5866159A (en) *	1988-09-16	1999-02-02	Novartis Ag	Pharmaceutical compositions comprising cyclosporins
US5916589A (en) *	1988-09-16	1999-06-29	Novartis Ag	Pharmaceutical compositions comprising cyclosporins
US5962017A (en) *	1988-09-16	1999-10-05	Novartis G	Pharmaceutical compositions comprising cyclosporins
US5962014A (en) *	1988-09-16	1999-10-05	Novartis Ag	Pharmaceutical compositions comprising cyclosporins
US6007840A (en) *	1988-09-16	1999-12-28	Novartis Ag	Pharmaceutical compositions comprising cyclosporins
US6024978A (en) *	1988-09-16	2000-02-15	Novartis Ag	Pharmaceutical compositions comprising cyclosporins
US7511014B2 (en)	1989-02-20	2009-03-31	Novartis Ag	Cyclosporin galenic forms
US7081445B2 (en)	1989-02-20	2006-07-25	Novartis Ag	Cyclosporin galenic forms
US6844459B2 (en)	1991-06-27	2005-01-18	Novartis Ag	Pharmaceutical Composition
US6258808B1 (en)	1991-06-27	2001-07-10	Novartis Ag	Pharmaceutical composition
US6582718B2 (en)	1992-05-13	2003-06-24	Novartis Ag	Cyclosporin compositions
US6262022B1 (en)	1992-06-25	2001-07-17	Novartis Ag	Pharmaceutical compositions containing cyclosporin as the active agent
US5670478A (en) *	1992-09-07	1997-09-23	Galena, A.S.	Pharmaceutical containing N-methylated cyclic undecapeptides
US6420355B2 (en)	1992-09-25	2002-07-16	Novartis Ag	Pharmaceutical compositions containing cyclosporins
US6486124B2 (en)	1994-11-03	2002-11-26	Novartis Ag	Cyclosporin compositions and process therefor
EP1676488A3 (fr) *	2000-06-26	2013-02-20	The Procter & Gamble Company	Compositions et procédés de régulation du poids corporel
WO2007047596A1 (fr) *	2005-10-17	2007-04-26	Hill's Pet Nutrition, Inc.	Méthode de réduction de l'absorption d'aliments et de diminution de l'appétit chez les animaux

Also Published As

Publication number	Publication date
BE874628A (fr)	1979-09-05
ZA791056B (en)	1980-10-29
HU182920B (en)	1984-03-28

Legal Events

Date	Code	Title	Description
1997-05-15	PFA	Name/firm changed	Owner name: SANDOZ AG TRANSFER- NOVARTIS AG
1998-03-31	PL	Patent ceased

Publication	Publication Date	Title
DE2907460C2 (fr)	1990-09-27
DE69403057T2 (de)	1997-08-14	Zusammensetzung, die bei peroraler verabreichung eine mikroemulsion bildet
DE69816335T2 (de)	2004-04-15	Cyclosporin-enthaltende mikroemulsion-vorkonzentratzusammensetzung
DE69328192T4 (de)	2007-07-19	Injizierbare Arzneizubereitungen enthaltend Taxanderivate
DE69309078T2 (de)	1997-09-11	N-methylierte zyklische undecapeptide enthaltende arzneimittelzubereitungen
DE4219526A1 (de)	1993-03-18	Pharmazeutisches mittel
DE2757827A1 (de)	1978-07-06	Arzneipraeparate mit einem gehalt an einem isosorbid-loesungsmittelsystem
CH636013A5 (en)	1983-05-13	More readily absorbable pharmaceutical composition
DE3040208A1 (de)	1981-05-07	Suppositoriengrundlage
CH641356A5 (en)	1984-02-29	Pharmaceutical compositions containing cyclosporin
DD203464A5 (de)	1983-10-26	Verfahren zur herstellung einer verbesserten oel-in-wasser-formulierung von 9-(2-hydroxy-aethoxymethyl)-guanin fuer lokale anwendung
DE3540175C2 (de)	1997-03-27	Dithranolhaltige pharmazeutische Zubereitung
DE3884945T2 (de)	1994-02-10	Emulsion für parenterale verabreichung.
DE69001513T2 (de)	1993-10-28	Polyprenylverbindung enthaltende Zusammensetzung für weiche Kapseln.
DE68906513T2 (de)	1993-09-09	Topisch anzuwendende diclofenac enthaltende arzneizubereitungen.
DE2241667C3 (de)	1975-04-30	Stabiles pharmazeutisches Mittel in Form einer wässrigen oralen anwendbaren Suspension
DE19517147C2 (de)	1999-07-01	Aciclovir-Zubereitung
DE69122229T2 (de)	1997-03-06	Penciclovir enthaltende pharmazeutische formulierung
DE4410637C1 (de)	1995-09-21	Injizierbare Lösungen von Dirithromycin
DE2347243A1 (de)	1974-10-10	Pharmazeutische zusammensetzungen
EP0009215B1 (fr)	1982-01-06	Pâtes endoparasiticides pour les chevaux
DE69008321T2 (de)	1994-09-29	Pharmazeutische Tebufelon-Zusammensetzungen.
DE1617653B1 (de)	1970-06-18	Indomethacinpraeparat zur externen Anwendung
DE2809618A1 (de)	1979-09-20	Neues therapeutisches praeparat und verfahren zu dessen herstellung
DE3712758C2 (de)	1997-09-25	Stabile Anti-Akne-Zusammensetzung auf der Basis von Erythromycin