CH640863A5 - Metodo per la preparazione di sali dell'acido (-)cis-1,2-epossipropilfosfonico. - Google Patents

Metodo per la preparazione di sali dell'acido (-)cis-1,2-epossipropilfosfonico. Download PDF

Info

Publication number: CH640863A5
Authority: CH; Switzerland
Prior art keywords: cis; acid; preparation; salt; solution
Prior art date: 1978-07-06

Application number

CH549079A

Other languages

English (en)

Italian (it)

Inventor

Mario Portelli

Giuseppe Cervato

Original Assignee

Zambon Chimica

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1978-07-06

Filing date

1979-06-12

Publication date

1984-01-31

1979-06-12 Application filed by Zambon Chimica filed Critical Zambon Chimica

1984-01-31 Publication of CH640863A5 publication Critical patent/CH640863A5/it

Links

150000003839 salts Chemical class 0.000 title description 11
238000000034 method Methods 0.000 title description 9
238000002360 preparation method Methods 0.000 title description 6
239000000243 solution Substances 0.000 description 13
229910001868 water Inorganic materials 0.000 description 13
MHAJPDPJQMAIIY-UHFFFAOYSA-N Hydrogen peroxide Chemical compound OO MHAJPDPJQMAIIY-UHFFFAOYSA-N 0.000 description 10
KFZMGEQAYNKOFK-UHFFFAOYSA-N Isopropanol Chemical compound CC(C)O KFZMGEQAYNKOFK-UHFFFAOYSA-N 0.000 description 8
239000002253 acid Substances 0.000 description 8
239000004593 Epoxy Substances 0.000 description 7
239000003795 chemical substances by application Substances 0.000 description 7
HEMHJVSKTPXQMS-UHFFFAOYSA-M sodium hydroxide Inorganic materials [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 description 6
238000003756 stirring Methods 0.000 description 6
XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 6
VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 description 4
238000007254 oxidation reaction Methods 0.000 description 4
159000000000 sodium salts Chemical class 0.000 description 4
QWMFKVNJIYNWII-UHFFFAOYSA-N 5-bromo-2-(2,5-dimethylpyrrol-1-yl)pyridine Chemical compound CC1=CC=C(C)N1C1=CC=C(Br)C=N1 QWMFKVNJIYNWII-UHFFFAOYSA-N 0.000 description 3
QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 description 3
239000007864 aqueous solution Substances 0.000 description 3
238000006243 chemical reaction Methods 0.000 description 3
239000000203 mixture Substances 0.000 description 3
231100000252 nontoxic Toxicity 0.000 description 3
230000003000 nontoxic effect Effects 0.000 description 3
230000003647 oxidation Effects 0.000 description 3
-1 p-methylmercaptophenyl Chemical group 0.000 description 3
239000002244 precipitate Substances 0.000 description 3
NWZSZGALRFJKBT-KNIFDHDWSA-N (2s)-2,6-diaminohexanoic acid;(2s)-2-hydroxybutanedioic acid Chemical compound OC(=O)[C@@H](O)CC(O)=O.NCCCC[C@H](N)C(O)=O NWZSZGALRFJKBT-KNIFDHDWSA-N 0.000 description 2
RYGMFSIKBFXOCR-UHFFFAOYSA-N Copper Chemical compound [Cu] RYGMFSIKBFXOCR-UHFFFAOYSA-N 0.000 description 2
QXNVGIXVLWOKEQ-UHFFFAOYSA-N Disodium Chemical class [Na][Na] QXNVGIXVLWOKEQ-UHFFFAOYSA-N 0.000 description 2
LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 2
NBIIXXVUZAFLBC-UHFFFAOYSA-N Phosphoric acid Chemical compound OP(O)(O)=O NBIIXXVUZAFLBC-UHFFFAOYSA-N 0.000 description 2
159000000007 calcium salts Chemical class 0.000 description 2
229910052802 copper Inorganic materials 0.000 description 2
239000010949 copper Substances 0.000 description 2
IKDUDTNKRLTJSI-UHFFFAOYSA-N hydrazine monohydrate Substances O.NN IKDUDTNKRLTJSI-UHFFFAOYSA-N 0.000 description 2
230000021962 pH elevation Effects 0.000 description 2
239000000047 product Substances 0.000 description 2
235000011121 sodium hydroxide Nutrition 0.000 description 2
239000000725 suspension Substances 0.000 description 2
GYDBYATURBDGIF-UHFFFAOYSA-N (2-methyloxiran-2-yl)phosphonic acid Chemical compound OP(=O)(O)C1(C)CO1 GYDBYATURBDGIF-UHFFFAOYSA-N 0.000 description 1
RQEUFEKYXDPUSK-UHFFFAOYSA-N 1-phenylethylamine Chemical compound CC(N)C1=CC=CC=C1 RQEUFEKYXDPUSK-UHFFFAOYSA-N 0.000 description 1
OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 description 1
ZGTMUACCHSMWAC-UHFFFAOYSA-L EDTA disodium salt (anhydrous) Chemical compound [Na+].[Na+].OC(=O)CN(CC([O-])=O)CCN(CC(O)=O)CC([O-])=O ZGTMUACCHSMWAC-UHFFFAOYSA-L 0.000 description 1
229910000147 aluminium phosphate Inorganic materials 0.000 description 1
244000052616 bacterial pathogen Species 0.000 description 1
230000003115 biocidal effect Effects 0.000 description 1
239000011575 calcium Substances 0.000 description 1
229910052791 calcium Inorganic materials 0.000 description 1
QHFQAJHNDKBRBO-UHFFFAOYSA-L calcium chloride hexahydrate Chemical compound O.O.O.O.O.O.[Cl-].[Cl-].[Ca+2] QHFQAJHNDKBRBO-UHFFFAOYSA-L 0.000 description 1
ZQNPDAVSHFGLIQ-UHFFFAOYSA-N calcium;hydrate Chemical compound O.[Ca] ZQNPDAVSHFGLIQ-UHFFFAOYSA-N 0.000 description 1
230000003197 catalytic effect Effects 0.000 description 1
238000002425 crystallisation Methods 0.000 description 1
230000008025 crystallization Effects 0.000 description 1
238000004821 distillation Methods 0.000 description 1
235000019441 ethanol Nutrition 0.000 description 1
150000004682 monohydrates Chemical class 0.000 description 1
230000003287 optical effect Effects 0.000 description 1
238000011084 recovery Methods 0.000 description 1
239000007858 starting material Substances 0.000 description 1
239000006188 syrup Substances 0.000 description 1
235000020357 syrup Nutrition 0.000 description 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/655—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms
- C07F9/65502—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms the oxygen atom being part of a three-membered ring
- C07F9/65505—Phosphonic acids containing oxirane groups; esters thereof

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Biochemistry (AREA)
General Health & Medical Sciences (AREA)
Molecular Biology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Epoxy Compounds (AREA)

CH549079A 1978-07-06 1979-06-12 Metodo per la preparazione di sali dell'acido (-)cis-1,2-epossipropilfosfonico. CH640863A5 (it)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
IT25389/78A IT1097477B (it)	1978-07-06	1978-07-06	Metodo per la preparazione di sali dell'acido (-) cis-1,2-epossipropilfosfonico

Publications (1)

Publication Number	Publication Date
CH640863A5 true CH640863A5 (it)	1984-01-31

Family

ID=11216556

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
CH549079A CH640863A5 (it)	1978-07-06	1979-06-12	Metodo per la preparazione di sali dell'acido (-)cis-1,2-epossipropilfosfonico.

Country Status (14)

Country	Link
JP (1)	JPS5511575A (da)
AT (1)	AT373264B (da)
CA (1)	CA1131648A (da)
CH (1)	CH640863A5 (da)
DE (1)	DE2925359C3 (da)
DK (1)	DK284679A (da)
ES (1)	ES482227A1 (da)
FR (1)	FR2430424A1 (da)
GB (1)	GB2024826B (da)
GR (1)	GR69597B (da)
IE (1)	IE48590B1 (da)
IT (1)	IT1097477B (da)
NL (1)	NL7905313A (da)
SE (1)	SE446739B (da)

1978
- 1978-07-06 IT IT25389/78A patent/IT1097477B/it active
1979
- 1979-06-09 JP JP7185879A patent/JPS5511575A/ja active Pending
- 1979-06-12 CH CH549079A patent/CH640863A5/it not_active IP Right Cessation
- 1979-06-22 FR FR7916110A patent/FR2430424A1/fr active Granted
- 1979-06-22 DE DE2925359A patent/DE2925359C3/de not_active Expired
- 1979-06-27 GB GB7922413A patent/GB2024826B/en not_active Expired
- 1979-06-28 AT AT0455279A patent/AT373264B/de not_active IP Right Cessation
- 1979-07-03 GR GR59500A patent/GR69597B/el unknown
- 1979-07-05 DK DK284679A patent/DK284679A/da not_active Application Discontinuation
- 1979-07-05 SE SE7905874A patent/SE446739B/sv not_active IP Right Cessation
- 1979-07-05 ES ES482227A patent/ES482227A1/es not_active Expired
- 1979-07-06 CA CA331,340A patent/CA1131648A/en not_active Expired
- 1979-07-06 NL NL7905313A patent/NL7905313A/nl not_active Application Discontinuation
- 1979-08-08 IE IE1272/79A patent/IE48590B1/en unknown

Also Published As

Publication number	Publication date
CA1131648A (en)	1982-09-14
ES482227A1 (es)	1980-04-01
GB2024826A (en)	1980-01-16
GB2024826B (en)	1982-12-01
SE7905874L (sv)	1980-01-07
IE48590B1 (en)	1985-03-20
SE446739B (sv)	1986-10-06
GR69597B (da)	1982-07-05
DE2925359C3 (de)	1981-08-06
DE2925359A1 (de)	1980-01-24
DK284679A (da)	1980-01-07
FR2430424A1 (fr)	1980-02-01
DE2925359B2 (de)	1980-09-04
AT373264B (de)	1984-01-10
JPS5511575A (en)	1980-01-26
ATA455279A (de)	1983-05-15
NL7905313A (nl)	1980-01-08
IT1097477B (it)	1985-08-31
FR2430424B1 (da)	1985-04-12
IT7825389A0 (it)	1978-07-06
IE791272L (en)	1980-01-06

Similar Documents

Publication	Publication Date	Title
ES8504838A1 (es)	1985-05-01	Un procedimiento para preparar el antibiotico l 17046
ATE232508T1 (de)	2003-02-15	Umweltschonendes verfahren zur herstellung von natriumchloridkristallen
SU668608A3 (ru)	1979-06-15	Способ получени -кристаллической формы натриевой соли 7-( -2-формилокси-2-фенилацетамидо)-3-(1-метил-1н-тетразолил-5-тиометил)-3-цефем-4-карбоновой кислоты
CH640823A5 (it)	1984-01-31	Bis-(2-ammonio-2-idrossimetil-1,3-propandiolo)(2r-cis)-(3-metilossiranil)fosfonato.
CH640863A5 (it)	1984-01-31	Metodo per la preparazione di sali dell'acido (-)cis-1,2-epossipropilfosfonico.
US5420302A (en)	1995-05-30	Preparation of calcium L-ascorbate 2-phosphate
US1978881A (en)	1934-10-30	Alkali salts of adenyl-pyrophosphoric acids
US5149829A (en)	1992-09-22	Method of preparing dry, concentrated salts of ascorbate 2-polyphosphate
RU2001909C1 (ru)	1993-10-30	Способ получени каптоприла
US2813118A (en)	1957-11-12	X-ray contrast compounds
KR830000567B1 (ko)	1983-03-14	(-)시스-1, 2-에폭시프로 필포스폰산의 염의 제조방법
JPS58222078A (ja)	1983-12-23	アスコルビン酸誘導体
RU2224763C2 (ru)	2004-02-27	Способ получения бис (1-гидроксиэтан-1,1-дифосфоната(1-)) меди (II)
KR820001739B1 (ko)	1982-09-27	헤파린의 회수방법
JP4418995B2 (ja)	2010-02-24	アスコルビン酸２−モノホスフェート塩の製造方法
US3687947A (en)	1972-08-29	Method for recovery of cephaloridine
KR940007419B1 (ko)	1994-08-18	고순도의 l-아스코빌-2-인산에스테르마그네슘의 정제방법
SU810675A1 (ru)	1981-03-07	Способ получени солей -лизина
US4438044A (en)	1984-03-20	Di-L-cysteine L-malate and process for the production thereof
US3812124A (en)	1974-05-21	Method for preparing thiamine salts
SU785293A1 (ru)	1980-12-07	Способ получени дифенил-2,2 ,6,6тетраальдегида
DE1545838C3 (de)	1975-12-11	7-(2-Azidooctanamido)-cephalosporansäure, deren Salze und Verfahren zur Herstellung dieser Verbindungen
US3595881A (en)	1971-07-27	Process for separating enantiomers of (cis-1,2-epoxypropyl)phosphonic acid
SU792835A1 (ru)	1982-05-07	Способ получени о-иодбензойный кислот или их производных,меченных радиоизотопами иода
SU62069A1 (ru)	1941-11-30	Способ выделени двойных серебр ных солей тиосерной кислоты из водных растворов

Legal Events

Date	Code	Title	Description
1988-06-15	PUE	Assignment	Owner name: ZAMBON GROUP S.P.A.
1995-02-28	PL	Patent ceased
2024-10-31	PL	Patent ceased