ES8504838A1 - Un procedimiento para preparar el antibiotico l 17046 - Google Patents

Un procedimiento para preparar el antibiotico l 17046

Info

Publication number
ES8504838A1
ES8504838A1 ES530815A ES530815A ES8504838A1 ES 8504838 A1 ES8504838 A1 ES 8504838A1 ES 530815 A ES530815 A ES 530815A ES 530815 A ES530815 A ES 530815A ES 8504838 A1 ES8504838 A1 ES 8504838A1
Authority
ES
Spain
Prior art keywords
antibiotic
preparing
acid
antimix
teicoplanine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES530815A
Other languages
English (en)
Other versions
ES530815A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Gruppo Lepetit SpA
Original Assignee
Gruppo Lepetit SpA
Lepetit SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gruppo Lepetit SpA, Lepetit SpA filed Critical Gruppo Lepetit SpA
Publication of ES8504838A1 publication Critical patent/ES8504838A1/es
Publication of ES530815A0 publication Critical patent/ES530815A0/es
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P1/00—Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes
    • C12P1/04—Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes by using bacteria
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K9/00—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof
    • C07K9/006—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence being part of a ring structure
    • C07K9/008—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence being part of a ring structure directly attached to a hetero atom of the saccharide radical, e.g. actaplanin, avoparcin, ristomycin, vancomycin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S930/00—Peptide or protein sequence
    • Y10S930/01—Peptide or protein sequence
    • Y10S930/19—Antibiotic
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S930/00—Peptide or protein sequence
    • Y10S930/01—Peptide or protein sequence
    • Y10S930/27—Cyclic peptide or cyclic protein

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Mycology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Oncology (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Saccharide Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Fodder In General (AREA)

Abstract

PROCEDIMIENTO PARA LA OBTENCION DEL ANTIBIOTICO L 17046 O UNA DE SUS SALES FISIOLOGICAMENTE COMPATIBLES, DE FORMULA (I).CONSISTE EN SOMETER UNA SUSTANCIA ANTIBIOTICA SELECCIONADA ENTRE TEICOPLANINA A2, SUS FACTORES PUROS, UNA DE SUS MEZCLAS O EL ANTIBIOTICO L 17054, A HIDROLISIS ACIDA, POR TRATAMIENTO CON ACIDO CLORHIDRICO 1N-3N, A UNA TEMPERATURA ENTRE 70JC Y 90JC, SEGUIDA DE LA RECUPERACION Y PURIFICACION DEL ANTIBIOTICO.ESTOS COMPUESTOS TIENEN APLICACIONES FARMACOLOGICAS POR SU ACTIVIDAD ANTIBACTERIANA.
ES530815A 1983-03-22 1984-03-21 Un procedimiento para preparar el antibiotico l 17046 Granted ES530815A0 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB838307847A GB8307847D0 (en) 1983-03-22 1983-03-22 Antibiotics l 17054 and l 17046

Publications (2)

Publication Number Publication Date
ES8504838A1 true ES8504838A1 (es) 1985-05-01
ES530815A0 ES530815A0 (es) 1985-05-01

Family

ID=10539998

Family Applications (2)

Application Number Title Priority Date Filing Date
ES530816A Expired ES8504839A1 (es) 1983-03-22 1984-03-21 Un procedimiento para preparar el antibiotico l 17054
ES530815A Granted ES530815A0 (es) 1983-03-22 1984-03-21 Un procedimiento para preparar el antibiotico l 17046

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ES530816A Expired ES8504839A1 (es) 1983-03-22 1984-03-21 Un procedimiento para preparar el antibiotico l 17054

Country Status (15)

Country Link
US (4) US4645827A (es)
EP (2) EP0119575B1 (es)
JP (2) JPS59213394A (es)
KR (2) KR910008645B1 (es)
AT (2) ATE38676T1 (es)
AU (2) AU567550B2 (es)
CA (2) CA1238041A (es)
DE (2) DE3475196D1 (es)
DK (2) DK161284A (es)
ES (2) ES8504839A1 (es)
GB (1) GB8307847D0 (es)
IE (2) IE57117B1 (es)
IL (2) IL71231A (es)
NZ (2) NZ207580A (es)
ZA (2) ZA842005B (es)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8307847D0 (en) * 1983-03-22 1983-04-27 Lepetit Spa Antibiotics l 17054 and l 17046
US4696817A (en) * 1983-10-11 1987-09-29 The Dow Chemical Company Extraction of teichomycin A2 from whole culture fermentation broth
AU579120B2 (en) * 1983-12-16 1988-11-17 Gruppo Lepetit S.P.A. Chemical process for preparing antibiotic L 17392 (deglucoteicoplanin) and its salts
GB8333624D0 (en) * 1983-12-16 1984-01-25 Lepetit Spa Antibiotics l 17054 and l 17392
IT1173329B (it) * 1984-02-21 1987-06-24 Lepetit Spa Procedimento per la trasformazione quantitativa di teicoplanina a2 fattore 1 in teicoplanina a2 fattore 3
GB8420405D0 (en) * 1984-08-10 1984-09-12 Lepetit Spa Preparing antibiotic l 17046
GB8428619D0 (en) * 1984-11-13 1984-12-19 Lepetit Spa Derivatives of antibiotic l 17046
IT1187705B (it) * 1985-07-24 1987-12-23 Montefluos Spa Polimeri fluorurati e resine da essi derivate
GB8522574D0 (en) * 1985-09-12 1985-10-16 Lepetit Spa Amides of teicoplanin compounds
GB8608809D0 (en) * 1986-04-11 1986-05-14 Lepetit Spa Antibiotic
US4845194A (en) * 1987-02-27 1989-07-04 Eli Lilly And Company Glycopeptide recovery process
GB8704847D0 (en) * 1987-03-02 1987-04-08 Lepetit Spa Substituted alkylamides of teicoplanin compounds
GB8715735D0 (en) * 1987-07-03 1987-08-12 Lepetit Spa De-mannosyl teicoplanin derivatives
EP0376042B1 (en) * 1988-12-27 1996-03-13 GRUPPO LEPETIT S.p.A. Improved chemical process for preparing antibiotic L 17392 (deglucoteicoplanin) and its salts
US5500410A (en) * 1989-03-29 1996-03-19 Gruppo Lepetit S.P.A. Substituted alkylamide derivatives of teicoplanin
US5185320A (en) * 1989-04-03 1993-02-09 Gruppo Lepetit S.P.A. O56 -alkyl derivatives of aglycone and pseudo aglycones of teicoplanin
DK0448940T3 (da) 1990-03-28 1997-11-03 Lepetit Spa Fremgangsmåde til fremstilling af mannosylteicoplaninderivater og mannosylteicoplaninaglycon
WO1992010516A1 (en) * 1990-12-05 1992-06-25 Gruppo Lepetit S.P.A. 38-decarboxy-38-hydroxymethyl derivatives of teicoplanin antibiotics, and a process for preparing them
US5455240A (en) * 1994-06-20 1995-10-03 The Rockefeller University Modulators of pneumococcal adhesion to cellular targets involving the platelet activating factor receptor, and uses thereof
KR20000010589A (ko) 1996-04-23 2000-02-15 클라우디오 쿼르타 항생제a40926의아미드유도체의개선된화학적제조방법
DK1516626T3 (da) * 2003-09-17 2007-04-30 Alpharma Aps Teicoplanin-sammensætning med forbedret antibiotisk aktivitet

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1496386A (en) * 1975-03-05 1977-12-30 Lepetit Spa Antibiotics
JPS5592387A (en) * 1978-12-29 1980-07-12 Taisho Pharmaceut Co Ltd Antibiotic substance tm-531
US4357325A (en) * 1981-04-20 1982-11-02 Eli Lilly And Company Methods of controlling Pasteurella infections
RO86375B1 (ro) * 1982-03-24 1985-04-01 Eli Lilly And Company Procedeu pentru prepararea antibioticului a 41030
FI73697C (fi) * 1982-06-08 1987-11-09 Lepetit Spa Foerfarande foer framstaellning av individuella faktorer 1, 2, 3, 4 och 5 av teikomysin a2.
US4485102A (en) * 1982-08-16 1984-11-27 American Cyanamid Company High potency, mycelial-free avoparcin alkyl sulfate complex, and method for the preparation thereof
GB8307847D0 (en) * 1983-03-22 1983-04-27 Lepetit Spa Antibiotics l 17054 and l 17046
US4489102A (en) * 1983-04-04 1984-12-18 At&T Technologies, Inc. Radiation-stimulated deposition of aluminum
US4479897A (en) * 1983-04-27 1984-10-30 Eli Lilly And Company Actaplanin antibiotics
US4521335A (en) * 1983-07-13 1985-06-04 Smithkline Beckman Corporation Aglycone and pseudo-aglycones of the AAD 216 antibiotics
GB8333624D0 (en) * 1983-12-16 1984-01-25 Lepetit Spa Antibiotics l 17054 and l 17392
IT1173329B (it) * 1984-02-21 1987-06-24 Lepetit Spa Procedimento per la trasformazione quantitativa di teicoplanina a2 fattore 1 in teicoplanina a2 fattore 3

Also Published As

Publication number Publication date
IE57118B1 (en) 1992-05-06
IL71230A (en) 1987-09-16
IL71231A0 (en) 1984-06-29
IE57117B1 (en) 1992-05-06
KR910008645B1 (ko) 1991-10-19
DK161284D0 (da) 1984-03-21
KR840008162A (ko) 1984-12-13
JPS59213395A (ja) 1984-12-03
EP0119574A3 (en) 1985-06-12
ES530816A0 (es) 1985-05-01
IE840692L (en) 1984-09-22
IL71230A0 (en) 1984-06-29
NZ207580A (en) 1987-03-31
US4650855A (en) 1987-03-17
GB8307847D0 (en) 1983-04-27
KR840008163A (ko) 1984-12-13
IE840691L (en) 1984-09-22
AU2589884A (en) 1984-09-27
ES8504839A1 (es) 1985-05-01
EP0119574A2 (en) 1984-09-26
DE3473148D1 (en) 1988-09-08
US5132286A (en) 1992-07-21
DK161284A (da) 1984-09-23
EP0119575A2 (en) 1984-09-26
CA1238041A (en) 1988-06-14
DK161184A (da) 1984-09-23
US4645827A (en) 1987-02-24
DE3475196D1 (en) 1988-12-22
ATE36163T1 (de) 1988-08-15
DK161184D0 (da) 1984-03-21
EP0119575A3 (en) 1985-06-19
JPS59213394A (ja) 1984-12-03
ATE38676T1 (de) 1988-12-15
AU567550B2 (en) 1987-11-26
ES530815A0 (es) 1985-05-01
ZA842006B (en) 1985-01-30
IL71231A (en) 1987-09-16
CA1238040A (en) 1988-06-14
NZ207579A (en) 1987-03-31
EP0119575B1 (en) 1988-08-03
US4699977A (en) 1987-10-13
AU2589784A (en) 1984-09-27
KR910008626B1 (ko) 1991-10-19
AU567549B2 (en) 1987-11-26
EP0119574B1 (en) 1988-11-17
ZA842005B (en) 1985-01-30

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19970401