CH646704A5 - Cephalosporin antibiotics, their preparation, and pharmaceutical compositions containing them - Google Patents

Cephalosporin antibiotics, their preparation, and pharmaceutical compositions containing them Download PDF

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Publication number
CH646704A5
CH646704A5 CH491979A CH491979A CH646704A5 CH 646704 A5 CH646704 A5 CH 646704A5 CH 491979 A CH491979 A CH 491979A CH 491979 A CH491979 A CH 491979A CH 646704 A5 CH646704 A5 CH 646704A5
Authority
CH
Switzerland
Prior art keywords
formula
compound
acid
carboxyl
group
Prior art date
Application number
CH491979A
Other languages
German (de)
English (en)
Inventor
Cynthia Hilda O'callaghan
David George Hubert Livermore
Christopher Earle Newall
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Publication of CH646704A5 publication Critical patent/CH646704A5/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/38—Nitrogen atoms
    • C07D277/40—Unsubstituted amino or imino radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/38—Nitrogen atoms
    • C07D277/42—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/587—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with aliphatic hydrocarbon radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms, said aliphatic radicals being substituted in the alpha-position to the ring by a hetero atom, e.g. with m >= 0, Z being a singly or a doubly bound hetero atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CH491979A 1978-05-26 1979-05-25 Cephalosporin antibiotics, their preparation, and pharmaceutical compositions containing them CH646704A5 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB22909/78A GB1604722A (en) 1978-05-26 1978-05-26 7-(2-(2-amino-4-thiozolyl)-2-oxymino-acetamido)-cephem derivatives

Publications (1)

Publication Number Publication Date
CH646704A5 true CH646704A5 (en) 1984-12-14

Family

ID=10187026

Family Applications (1)

Application Number Title Priority Date Filing Date
CH491979A CH646704A5 (en) 1978-05-26 1979-05-25 Cephalosporin antibiotics, their preparation, and pharmaceutical compositions containing them

Country Status (9)

Country Link
JP (2) JPS54154789A (fr)
BE (2) BE876541A (fr)
CH (1) CH646704A5 (fr)
DE (1) DE2921288A1 (fr)
FR (1) FR2426693A1 (fr)
GB (1) GB1604722A (fr)
IT (1) IT1116196B (fr)
NL (1) NL7904127A (fr)
ZA (1) ZA792584B (fr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE878514A (fr) * 1978-09-04 1980-02-29 Fujisawa Pharmaceutical Co Procede de preparation de composes d'acide 3-cephem-4-carboxylique a disubstitution en positions 3 et 7, nouveaux produits ainsi obtenus et leur utilisation pour leur activite antibacterienne
EP0346465B1 (fr) * 1986-04-14 1993-08-11 Banyu Pharmaceutical Co., Ltd. Derives de 1-carboxy-1-vinyloxyiminoaminothiazole cephalosporine et leur procede de preparation

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1576625A (en) * 1976-04-12 1980-10-08 Fujisawa Pharmaceutical Co Syn isomer 3,7 disubstituted 3 cephem 4 carboxylic acid compounds and processes for the preparation thereof

Also Published As

Publication number Publication date
DE2921288A1 (de) 1979-12-06
FR2426693B1 (fr) 1983-02-04
JPS54154789A (en) 1979-12-06
BE876542A (fr) 1979-11-26
GB1604722A (en) 1981-12-16
BE876541A (fr) 1979-11-26
IT7949177A0 (it) 1979-05-25
ZA792584B (en) 1980-07-30
JPS54154788A (en) 1979-12-06
FR2426693A1 (fr) 1979-12-21
IT1116196B (it) 1986-02-10
NL7904127A (nl) 1979-11-28

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Legal Events

Date Code Title Description
PL Patent ceased
PL Patent ceased