CH651473A5 - Pharmazeutisches praeparat. - Google Patents

Pharmazeutisches praeparat. Download PDF

Info

Publication number: CH651473A5
Authority: CH; Switzerland
Prior art keywords: dds; brodimoprim; leprosy; culture; growth
Prior art date: 1982-07-29

Application number

CH4600/82A

Other languages

German (de)

English (en)

Inventor

Joachim Karl Prof Dr Seydel

Original Assignee

Joachim Karl Prof Dr Seydel

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1982-07-29

Filing date

1982-07-29

Publication date

1985-09-30

1982-07-29 Application filed by Joachim Karl Prof Dr Seydel filed Critical Joachim Karl Prof Dr Seydel

1982-07-29 Priority to CH4600/82A priority Critical patent/CH651473A5/de

1983-07-15 Priority to IT22089/83A priority patent/IT1171692B/it

1983-07-19 Priority to NL8302579A priority patent/NL194535C/nl

1983-07-20 Priority to DE19833326165 priority patent/DE3326165A1/de

1983-07-21 Priority to FR8312071A priority patent/FR2531861B1/fr

1983-07-26 Priority to JP58135265A priority patent/JPS5933218A/ja

1983-07-28 Priority to GB08320438A priority patent/GB2125293B/en

1983-07-28 Priority to BE0/211250A priority patent/BE897397A/fr

1985-09-30 Publication of CH651473A5 publication Critical patent/CH651473A5/de

Links

239000000825 pharmaceutical preparation Substances 0.000 title claims 7
MQJKPEGWNLWLTK-UHFFFAOYSA-N Dapsone Chemical compound C1=CC(N)=CC=C1S(=O)(=O)C1=CC=C(N)C=C1 MQJKPEGWNLWLTK-UHFFFAOYSA-N 0.000 claims 15
BFCRRLMMHNLSCP-UHFFFAOYSA-N brodimoprim Chemical compound COC1=C(Br)C(OC)=CC(CC=2C(=NC(N)=NC=2)N)=C1 BFCRRLMMHNLSCP-UHFFFAOYSA-N 0.000 claims 12
229960000252 brodimoprim Drugs 0.000 claims 8
206010024229 Leprosy Diseases 0.000 claims 6
238000002360 preparation method Methods 0.000 claims 6
239000000725 suspension Substances 0.000 claims 6
239000004480 active ingredient Substances 0.000 claims 5
239000003112 inhibitor Substances 0.000 claims 5
HQKMJHAJHXVSDF-UHFFFAOYSA-L magnesium stearate Chemical compound [Mg+2].CCCCCCCCCCCCCCCCCC([O-])=O.CCCCCCCCCCCCCCCCCC([O-])=O HQKMJHAJHXVSDF-UHFFFAOYSA-L 0.000 claims 4
239000000243 solution Substances 0.000 claims 4
241000894006 Bacteria Species 0.000 claims 3
WSFSSNUMVMOOMR-UHFFFAOYSA-N Formaldehyde Chemical compound O=C WSFSSNUMVMOOMR-UHFFFAOYSA-N 0.000 claims 3
239000000203 mixture Substances 0.000 claims 3
241001147830 Mycobacterium lufu Species 0.000 claims 2
FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 claims 2
239000013543 active substance Substances 0.000 claims 2
230000000694 effects Effects 0.000 claims 2
235000019359 magnesium stearate Nutrition 0.000 claims 2
244000005700 microbiome Species 0.000 claims 2
244000052769 pathogen Species 0.000 claims 2
239000000843 powder Substances 0.000 claims 2
108091003079 Bovine Serum Albumin Proteins 0.000 claims 1
108010010803 Gelatin Proteins 0.000 claims 1
229920000084 Gum arabic Polymers 0.000 claims 1
GUBGYTABKSRVRQ-QKKXKWKRSA-N Lactose Natural products OC[C@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)C(O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@H]1O GUBGYTABKSRVRQ-QKKXKWKRSA-N 0.000 claims 1
229920000881 Modified starch Polymers 0.000 claims 1
229920003081 Povidone K 30 Polymers 0.000 claims 1
229920003110 Primojel Polymers 0.000 claims 1
229920002472 Starch Polymers 0.000 claims 1
235000010489 acacia gum Nutrition 0.000 claims 1
239000000205 acacia gum Substances 0.000 claims 1
239000000443 aerosol Substances 0.000 claims 1
239000000730 antalgic agent Substances 0.000 claims 1
239000002260 anti-inflammatory agent Substances 0.000 claims 1
229940121363 anti-inflammatory agent Drugs 0.000 claims 1
239000002221 antipyretic Substances 0.000 claims 1
229940125716 antipyretic agent Drugs 0.000 claims 1
230000001580 bacterial effect Effects 0.000 claims 1
244000052616 bacterial pathogen Species 0.000 claims 1
229940098773 bovine serum albumin Drugs 0.000 claims 1
239000006172 buffering agent Substances 0.000 claims 1
239000002775 capsule Substances 0.000 claims 1
239000012876 carrier material Substances 0.000 claims 1
239000002552 dosage form Substances 0.000 claims 1
239000003937 drug carrier Substances 0.000 claims 1
239000003995 emulsifying agent Substances 0.000 claims 1
239000000839 emulsion Substances 0.000 claims 1
239000008273 gelatin Substances 0.000 claims 1
229920000159 gelatin Polymers 0.000 claims 1
235000019322 gelatine Nutrition 0.000 claims 1
235000011852 gelatine desserts Nutrition 0.000 claims 1
239000008187 granular material Substances 0.000 claims 1
239000004615 ingredient Substances 0.000 claims 1
230000000977 initiatory effect Effects 0.000 claims 1
239000008101 lactose Substances 0.000 claims 1
235000019426 modified starch Nutrition 0.000 claims 1
235000015097 nutrients Nutrition 0.000 claims 1
239000002674 ointment Substances 0.000 claims 1
230000003204 osmotic effect Effects 0.000 claims 1
238000007911 parenteral administration Methods 0.000 claims 1
239000006187 pill Substances 0.000 claims 1
229920001515 polyalkylene glycol Polymers 0.000 claims 1
235000013855 polyvinylpyrrolidone Nutrition 0.000 claims 1
229920000036 polyvinylpyrrolidone Polymers 0.000 claims 1
239000001267 polyvinylpyrrolidone Substances 0.000 claims 1
239000003755 preservative agent Substances 0.000 claims 1
150000003839 salts Chemical class 0.000 claims 1
238000005070 sampling Methods 0.000 claims 1
238000009097 single-agent therapy Methods 0.000 claims 1
239000011780 sodium chloride Substances 0.000 claims 1
239000003381 stabilizer Substances 0.000 claims 1
235000019698 starch Nutrition 0.000 claims 1
239000008107 starch Substances 0.000 claims 1
239000008174 sterile solution Substances 0.000 claims 1
239000000126 substance Substances 0.000 claims 1
239000006228 supernatant Substances 0.000 claims 1
230000002195 synergetic effect Effects 0.000 claims 1
239000006188 syrup Substances 0.000 claims 1
235000020357 syrup Nutrition 0.000 claims 1
239000003826 tablet Substances 0.000 claims 1
239000000454 talc Substances 0.000 claims 1
229910052623 talc Inorganic materials 0.000 claims 1
235000012222 talc Nutrition 0.000 claims 1
230000001225 therapeutic effect Effects 0.000 claims 1
229940099259 vaseline Drugs 0.000 claims 1
235000015112 vegetable and seed oil Nutrition 0.000 claims 1
239000008158 vegetable oil Substances 0.000 claims 1
XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims 1
239000000080 wetting agent Substances 0.000 claims 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A61P31/08—Antibacterial agents for leprosy

Landscapes

Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Chemical & Material Sciences (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Organic Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Oncology (AREA)
Communicable Diseases (AREA)
Epidemiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

CH4600/82A 1982-07-29 1982-07-29 Pharmazeutisches praeparat. CH651473A5 (de)

Priority Applications (8)

Application Number	Priority Date	Filing Date	Title
CH4600/82A CH651473A5 (de)	1982-07-29	1982-07-29	Pharmazeutisches praeparat.
IT22089/83A IT1171692B (it)	1982-07-29	1983-07-15	Preparato farmaceutico impiegabile per il trattamento della lebbra e/o di altre micobatteriosi
NL8302579A NL194535C (nl)	1982-07-29	1983-07-19	Farmaceutisch preparaat voor de behandeling van lepra dat diaminodifenylsulfon bevat.
DE19833326165 DE3326165A1 (de)	1982-07-29	1983-07-20	Pharmazeutisches praeparat
FR8312071A FR2531861B1 (fr)	1982-07-29	1983-07-21	Preparation pharmaceutique synergique a base de dds et de brodimoprim, pour le traitement de la lepre
JP58135265A JPS5933218A (ja)	1982-07-29	1983-07-26	抗マイコバクテリア組成物
GB08320438A GB2125293B (en)	1982-07-29	1983-07-28	Pharmaceutical preparation containing diaminodiphenylsulphone and brodimoprim
BE0/211250A BE897397A (fr)	1982-07-29	1983-07-28	Preparation pharmaceutique

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
CH4600/82A CH651473A5 (de)	1982-07-29	1982-07-29	Pharmazeutisches praeparat.

Publications (1)

Publication Number	Publication Date
CH651473A5 true CH651473A5 (de)	1985-09-30

Family

ID=4279115

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
CH4600/82A CH651473A5 (de)	1982-07-29	1982-07-29	Pharmazeutisches praeparat.

Country Status (8)

Country	Link
JP (1)	JPS5933218A (fr)
BE (1)	BE897397A (fr)
CH (1)	CH651473A5 (fr)
DE (1)	DE3326165A1 (fr)
FR (1)	FR2531861B1 (fr)
GB (1)	GB2125293B (fr)
IT (1)	IT1171692B (fr)
NL (1)	NL194535C (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DK387687A (da) *	1986-07-28	1988-01-29	Warner Lambert Co	Fremstilling af farmaceutisk praeparat til behandling af infektioner med mycobacterium avium-intracellulare komplekset

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
SE419444B (sv) *	1973-11-08	1981-08-03	Hoffmann La Roche	Forfarande for framstellning av nya 2,4-diamino-5-bensylpyrimidinderivat
ZW10681A1 (en) *	1980-06-26	1982-02-24	Hoffmann La Roche	Antibacterial agents
GB2082063A (en) *	1980-08-15	1982-03-03	Haughey Edward	Antibacterial drug

1982
- 1982-07-29 CH CH4600/82A patent/CH651473A5/de not_active IP Right Cessation
1983
- 1983-07-15 IT IT22089/83A patent/IT1171692B/it active
- 1983-07-19 NL NL8302579A patent/NL194535C/nl not_active IP Right Cessation
- 1983-07-20 DE DE19833326165 patent/DE3326165A1/de active Granted
- 1983-07-21 FR FR8312071A patent/FR2531861B1/fr not_active Expired
- 1983-07-26 JP JP58135265A patent/JPS5933218A/ja active Granted
- 1983-07-28 BE BE0/211250A patent/BE897397A/fr not_active IP Right Cessation
- 1983-07-28 GB GB08320438A patent/GB2125293B/en not_active Expired

Also Published As

Publication number	Publication date
JPS5933218A (ja)	1984-02-23
JPH0419968B2 (fr)	1992-03-31
IT8322089A0 (it)	1983-07-15
FR2531861A1 (fr)	1984-02-24
NL8302579A (nl)	1984-02-16
NL194535C (nl)	2002-07-02
BE897397A (fr)	1984-01-30
GB2125293A (en)	1984-03-07
NL194535B (nl)	2002-03-01
GB8320438D0 (en)	1983-09-01
DE3326165C2 (fr)	1993-07-22
IT1171692B (it)	1987-06-10
FR2531861B1 (fr)	1987-08-28
IT8322089A1 (it)	1985-01-15
DE3326165A1 (de)	1984-04-12
GB2125293B (en)	1985-11-13

Legal Events

Date	Code	Title	Description
1986-01-15	PUE	Assignment	Owner name: F. HOFFMANN-LA ROCHE & CO. AKTIENGESELLSCHAFT
1990-02-15	PUE	Assignment	Owner name: F. HOFFMANN-LA ROCHE AG
2002-08-30	PL	Patent ceased

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DE69122298T2 (de)	1997-02-06	Behandlung von Clostridium difficile Diarrhöe und pseudomembraner Dickdarmentzündung
AT401470B (de)	1996-09-25	Pharmazeutische verwendung von 17-ketosteroiden
DE69725879T2 (de)	2004-09-02	VERWENDUNG VON p-AMINOPHENOLDERIVATEN ZUR HERSTELLUNG VON PHARMAZEUTISCHEN ZUSAMMENSETZUNGEN ZUR BEHANDLUNG VON NEURODEGENERATIVEN ERKRANKUNGEN
DD241271A5 (de)	1986-12-03	Verfahren zur unterscheidung von normalen und boesartigen zellen in einer mischung in vitro
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DE69819012T2 (de)	2004-08-12	Pharmazeutische zusammensetzung zur reduzierung der mcp-1 proteinsynthese
Hobby et al.	1953	In vitro and in vivo activity of streptomycin and isoniazid singly and in combination
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Leslie et al.	1978	Cytotoxicity of butylated hydroxytoluene and butylated hydroxyanisole in cultured heart cells
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DE3856052T2 (de)	1998-02-19	Anwendung des N-n-butyl-Derivates von Desoxynojirimycin zur Herstellung eines Arzneimittels zur Inhibierung von HIV-Virus
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