CH663616A5 - 1,4-dihydropyridin-derivate und sie enthaltende pharmazeutische zubereitungen. - Google Patents

1,4-dihydropyridin-derivate und sie enthaltende pharmazeutische zubereitungen. Download PDF

Info

Publication number
CH663616A5
CH663616A5 CH784/85A CH78485A CH663616A5 CH 663616 A5 CH663616 A5 CH 663616A5 CH 784/85 A CH784/85 A CH 784/85A CH 78485 A CH78485 A CH 78485A CH 663616 A5 CH663616 A5 CH 663616A5
Authority
CH
Switzerland
Prior art keywords
carbon atoms
alkyl
hydrogen
alkoxy
defined above
Prior art date
Application number
CH784/85A
Other languages
German (de)
English (en)
Inventor
Arnold Vogel
Original Assignee
Sandoz Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz Ag filed Critical Sandoz Ag
Publication of CH663616A5 publication Critical patent/CH663616A5/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/08Bronchodilators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/20Hypnotics; Sedatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/08Vasodilators for multiple indications
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C309/00Sulfonic acids; Halides, esters, or anhydrides thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/80Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D211/84Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
    • C07D211/90Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
CH784/85A 1983-06-21 1984-06-13 1,4-dihydropyridin-derivate und sie enthaltende pharmazeutische zubereitungen. CH663616A5 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH339483 1983-06-21

Publications (1)

Publication Number Publication Date
CH663616A5 true CH663616A5 (de) 1987-12-31

Family

ID=4255028

Family Applications (1)

Application Number Title Priority Date Filing Date
CH784/85A CH663616A5 (de) 1983-06-21 1984-06-13 1,4-dihydropyridin-derivate und sie enthaltende pharmazeutische zubereitungen.

Country Status (15)

Country Link
JP (1) JPS6013789A (ja)
AU (1) AU2956484A (ja)
BE (1) BE899937A (ja)
CH (1) CH663616A5 (ja)
DE (1) DE3421992A1 (ja)
DK (1) DK299784A (ja)
FR (1) FR2549058B1 (ja)
GB (1) GB2142021B (ja)
IL (1) IL72152A0 (ja)
IT (1) IT1199143B (ja)
LU (1) LU85423A1 (ja)
NL (1) NL8401932A (ja)
SE (1) SE8403268L (ja)
WO (1) WO1985000169A1 (ja)
ZA (1) ZA844725B (ja)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4755512A (en) * 1984-04-11 1988-07-05 Bristol-Myers Company Pharmaceutically useful dihydropyridinyldicarboxylate amides and esters incorporating arylpiperazinylalkyl moities
NL8503262A (nl) * 1984-12-10 1986-07-01 Sandoz Ag 1,4-dihydropyridinederivaten, werkwijze voor het bereiden van deze derivaten en farmaceutische preparaten die ze bevatten.
EP0191724A3 (de) * 1985-01-15 1986-12-03 Sandoz Ag 1,4-Dihydropyridine, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Zusammensetzungen
US4659717A (en) * 1985-08-21 1987-04-21 Eli Lilly And Company Dihydropyridines useful in the treatment of angina and stroke
EP0222702A3 (de) * 1985-11-06 1988-01-07 Ciba-Geigy Ag Basische Carbonylverbindungen
US4868181A (en) * 1986-08-04 1989-09-19 E. I. Du Pont De Nemours And Company 1,4-dihydropyridine derivatives with calcium agonist and alpha1 -antagonist activity
WO1988007525A1 (fr) * 1987-03-27 1988-10-06 Byk Gulden Lomberg Chemische Fabrik Gmbh Enantiomeres de 1,4-dihydropyridine
AU1541188A (en) * 1987-03-27 1988-11-02 Byk Gulden Lomberg Chemische Fabrik Gmbh New optically active compounds
AU2614288A (en) * 1987-10-27 1989-05-23 Byk Gulden Lomberg Chemische Fabrik Gmbh New pyrrolidines
JPH10205466A (ja) * 1997-01-23 1998-08-04 Mitsubishi Heavy Ind Ltd スクロール型流体機械

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2949464A1 (de) * 1978-12-18 1980-06-26 Sandoz Ag Benzoxadiazole und benzothiadiazole, ihre herstellung und verwendung
DE3022030A1 (de) * 1980-06-12 1981-12-17 Bayer Ag, 5090 Leverkusen 4-thiazol- bzw. 4-imidazol-substituierte, 1,4-dihydropyridine, verfahren zu deren herstellung sowie diese enthaltende arzneimittel
JPS57175165A (en) * 1981-04-21 1982-10-28 Tokyo Tanabe Co Ltd Novel 1,4-dihydropyridine-3,5-dicarboxylic diester derivative and its salt
DE3208628A1 (de) * 1982-03-10 1983-09-22 Bayer Ag, 5090 Leverkusen Neue verbindungen, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel
ATE50987T1 (de) * 1982-05-10 1990-03-15 Takeda Chemical Industries Ltd Dihydropyridinderivate, deren herstellung und verwendung.

Also Published As

Publication number Publication date
SE8403268D0 (sv) 1984-06-19
GB2142021B (en) 1987-07-15
GB2142021A (en) 1985-01-09
BE899937A (fr) 1984-12-18
NL8401932A (nl) 1985-01-16
WO1985000169A1 (fr) 1985-01-17
IT1199143B (it) 1988-12-30
JPS6013789A (ja) 1985-01-24
AU2956484A (en) 1985-01-03
LU85423A1 (fr) 1985-03-26
IT8448415A0 (it) 1984-06-19
GB8415523D0 (en) 1984-07-25
FR2549058A1 (fr) 1985-01-18
DK299784A (da) 1984-12-22
IT8448415A1 (it) 1985-12-19
DK299784D0 (da) 1984-06-19
IL72152A0 (en) 1984-10-31
ZA844725B (en) 1986-02-26
DE3421992A1 (de) 1985-01-03
FR2549058B1 (fr) 1988-02-19
SE8403268L (sv) 1984-12-22

Similar Documents

Publication Publication Date Title
DE69229834T2 (de) Piperazinderivate als 5-ht rezeptor antagonisten
DE69014351T2 (de) Pyridincarbonsäureamid-Derivate und diese enthaltende pharmazeutische Zusammensetzungen.
DE2824064A1 (de) Phthalazin-derivate, ihre herstellung und solche derivate enthaltende arzneimittel
EP0013894B1 (de) Neue Arylether, Verfahren zu deren Herstellung sowie diese Verbindungen enthaltende Arzneimittel
DE3878371T2 (de) Psychotropische bizyklische imide.
EP0025111A1 (en) 3-Aminopropoxyaryl derivatives, their preparation and pharmaceutical compositions containing them
DE69120899T2 (de) Neue N-Benzoylprolin-Derivate, Verfahren zur Herstellung und diese enthaltende Arzneimittel
DE3882679T2 (de) Kardiovaskulaer aktive verbindungen.
CH663616A5 (de) 1,4-dihydropyridin-derivate und sie enthaltende pharmazeutische zubereitungen.
DE3781174T2 (de) Verwendung von aromatischen diaminen fuer die behandlung von angina pectoris und diamine dafuer.
DE69207301T2 (de) Substituierte 3-Piperazinylalkyl 2,3-Dihydro-4H-1,3-Benzoxazin-4-One, deren Herstellung und Verwendung in Heilkunde
DE69216260T2 (de) Piperidinderivate
DE3309596A1 (de) 2-substituierte 1-(3'-aminoalkyl)-1,2,3,4-tetrahydro-ss-carboline, ihre herstellung und verwendung als arzneimittel
DE69612753T2 (de) (r)-5-bromo-n-(1-ethyl-4-methylhexahydro-1h-1,4-diazepin-6-yl)-2-methoxy-6-methylamino-3-pyridincarboxamid, verfahren zu seinerherstellung und dieses enthaltende medizinische zubereitung
DE69228042T2 (de) Naphthamide, Verfahren zur Herstellung und ihre therapeutische Anwendung
DE69302544T2 (de) 2-amino-1,2,3,4-tetrahydronaphthalen derivate mit wirkung auf das kardiovasculäre system, verfahren zu deren herstellung und deren pharmazeutische zusammensetzungen
DD145104B3 (de) Verfahren zur herstellung von polyalkoxyphenylpyrrolidone
DD143613A5 (de) Verfahren zur herstellung von 4-amino-2-piperidino-chinazolin-derivaten
DE69014930T2 (de) Aralkylamin-Verbindungen.
KR870001681B1 (ko) 히단토인 유도체의 제조방법
EP0342182A1 (de) Derivate von 5-Aminomethyl-2-furanmethanol, ihre Herstellung und Verwendung
DE3424586A1 (de) 3-aminocarbonylmethoxy-5-phenyl-pyrazol-verbindungen sowie verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
DD213921A5 (de) Verfahren zur herstellung von substituierten nicotinamid 1-oxyd n- und seinen salzen
EP0412058A1 (en) 1-acyl-2-pyrrolidinones as enhancers of learning and memory and pharmaceutical compositions containing same
EP0106276B1 (en) 1,4-dihydropyridine derivatives

Legal Events

Date Code Title Description
PL Patent ceased
PL Patent ceased