CL2004000677A1 - Compuestos derivados de piperidinas; procedimiento de preparacion; composicion farmaceutica; utiles como moduladores de la actividad del receptor de quimioquina en el tratamiento de enfermedades autoinmunes, inflamatorias, proliferativas o mediadas i - Google Patents

Compuestos derivados de piperidinas; procedimiento de preparacion; composicion farmaceutica; utiles como moduladores de la actividad del receptor de quimioquina en el tratamiento de enfermedades autoinmunes, inflamatorias, proliferativas o mediadas i

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Publication number
CL2004000677A1
CL2004000677A1 CL200400677A CL2004000677A CL2004000677A1 CL 2004000677 A1 CL2004000677 A1 CL 2004000677A1 CL 200400677 A CL200400677 A CL 200400677A CL 2004000677 A CL2004000677 A CL 2004000677A CL 2004000677 A1 CL2004000677 A1 CL 2004000677A1
Authority
CL
Chile
Prior art keywords
chemioquine
piperidins
proliferative
modulators
autoimmune
Prior art date
Application number
CL200400677A
Other languages
English (en)
Inventor
Moya Luckhurst Chris M Caffrey
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of CL2004000677A1 publication Critical patent/CL2004000677A1/es

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    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/40Oxygen atoms
    • C07D211/44Oxygen atoms attached in position 4
    • C07D211/46Oxygen atoms attached in position 4 having a hydrogen atom as the second substituent in position 4
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
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    • A61P31/14Antivirals for RNA viruses
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    • AHUMAN NECESSITIES
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    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/18Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D211/26Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by nitrogen atoms

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  • General Chemical & Material Sciences (AREA)
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  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
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  • Veterinary Medicine (AREA)
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  • Pain & Pain Management (AREA)
CL200400677A 2003-04-01 2004-03-30 Compuestos derivados de piperidinas; procedimiento de preparacion; composicion farmaceutica; utiles como moduladores de la actividad del receptor de quimioquina en el tratamiento de enfermedades autoinmunes, inflamatorias, proliferativas o mediadas i CL2004000677A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE0300957A SE0300957D0 (sv) 2003-04-01 2003-04-01 Chemical compounds

Publications (1)

Publication Number Publication Date
CL2004000677A1 true CL2004000677A1 (es) 2005-04-22

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ID=20290898

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CL200400677A CL2004000677A1 (es) 2003-04-01 2004-03-30 Compuestos derivados de piperidinas; procedimiento de preparacion; composicion farmaceutica; utiles como moduladores de la actividad del receptor de quimioquina en el tratamiento de enfermedades autoinmunes, inflamatorias, proliferativas o mediadas i

Country Status (24)

Country Link
US (2) US7495013B2 (es)
EP (1) EP1620400B1 (es)
JP (1) JP3911006B2 (es)
KR (1) KR20050108419A (es)
CN (1) CN100460391C (es)
AR (1) AR043820A1 (es)
AU (1) AU2004226010B2 (es)
BR (1) BRPI0409069A (es)
CA (1) CA2521073A1 (es)
CL (1) CL2004000677A1 (es)
CO (1) CO5611151A2 (es)
ES (1) ES2398462T3 (es)
IS (1) IS8089A (es)
MX (1) MXPA05010374A (es)
MY (1) MY135396A (es)
NO (1) NO20055068L (es)
NZ (1) NZ542506A (es)
RU (1) RU2005128793A (es)
SE (1) SE0300957D0 (es)
TW (1) TW200505857A (es)
UA (1) UA81014C2 (es)
UY (1) UY28248A1 (es)
WO (1) WO2004087659A1 (es)
ZA (1) ZA200507943B (es)

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GB0122503D0 (en) 2001-09-18 2001-11-07 Astrazeneca Ab Chemical compounds
AU2003209204A1 (en) * 2002-01-10 2003-07-30 University Of Washington Hydrogels formed by non-covalent linkages
SE0200844D0 (sv) 2002-03-19 2002-03-19 Astrazeneca Ab Chemical compounds
SE0200843D0 (sv) * 2002-03-19 2002-03-19 Astrazeneca Ab Chemical compounds
SE0202838D0 (sv) * 2002-09-24 2002-09-24 Astrazeneca Ab Chemical compounds
SE0301368D0 (sv) * 2003-05-09 2003-05-09 Astrazeneca Ab Chemical compounds
SE0400925D0 (sv) * 2004-04-06 2004-04-06 Astrazeneca Ab Chemical compounds
TW200722419A (en) * 2005-05-27 2007-06-16 Astrazeneca Ab Chemical compounds
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MXPA05010374A (es) 2005-11-17
US20070032523A1 (en) 2007-02-08
IS8089A (is) 2005-10-25
US7495013B2 (en) 2009-02-24
US20090118513A1 (en) 2009-05-07
SE0300957D0 (sv) 2003-04-01
TW200505857A (en) 2005-02-16
UY28248A1 (es) 2004-11-08
CO5611151A2 (es) 2006-02-28
NZ542506A (en) 2008-09-26
AU2004226010A1 (en) 2004-10-14
UA81014C2 (en) 2007-11-26
EP1620400B1 (en) 2012-12-05
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MY135396A (en) 2008-04-30
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CN1768037A (zh) 2006-05-03
RU2005128793A (ru) 2006-05-10
AR043820A1 (es) 2005-08-17
WO2004087659A1 (en) 2004-10-14
CN100460391C (zh) 2009-02-11
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