CL2004000979A1 - Nonapeptidos acilados tipo lysobacitina, composicion que los contiene metodo de preparacion, util como bactericida. - Google Patents

Nonapeptidos acilados tipo lysobacitina, composicion que los contiene metodo de preparacion, util como bactericida.

Info

Publication number
CL2004000979A1
CL2004000979A1 CL200400979A CL2004000979A CL2004000979A1 CL 2004000979 A1 CL2004000979 A1 CL 2004000979A1 CL 200400979 A CL200400979 A CL 200400979A CL 2004000979 A CL2004000979 A CL 2004000979A CL 2004000979 A1 CL2004000979 A1 CL 2004000979A1
Authority
CL
Chile
Prior art keywords
preparation
lysobacitine
nonapeptides
bactericide
closed
Prior art date
Application number
CL200400979A
Other languages
English (en)
Inventor
Nussgaum Franz Von
Nina Brunner
Sonja Anlauf
Rainer Endermann
Chantal Furstner
Elke Hartmann
Johannes Kobberling
Jacques Ragot
Original Assignee
Bayer Healthcare Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Healthcare Ag filed Critical Bayer Healthcare Ag
Publication of CL2004000979A1 publication Critical patent/CL2004000979A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06008—Dipeptides with the first amino acid being neutral
    • C07K5/06078—Dipeptides with the first amino acid being neutral and aromatic or cycloaliphatic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06008—Dipeptides with the first amino acid being neutral
    • C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
    • C07K5/06026—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atom, i.e. Gly or Ala
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06008—Dipeptides with the first amino acid being neutral
    • C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
    • C07K5/06034—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 2 to 4 carbon atoms
    • C07K5/06043—Leu-amino acid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06008—Dipeptides with the first amino acid being neutral
    • C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
    • C07K5/0606—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing heteroatoms not provided for by C07K5/06086 - C07K5/06139, e.g. Ser, Met, Cys, Thr
    • C07K5/06069—Ser-amino acid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Oncology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

NONADEPSIPEPTIDOS DE FORMULA (I) COMPOSICIONES QUE LOS CONTIENEN Y SU USO PARA LA PREPARACION DE MEDICAMENTOS PARA EL TRATAMIENTO Y/O PROFILAXIS DE ENFERMEDADES, ESPECIALMENTE ENFERMEDADES INFECCIOSAS BACTERIANAS. EL PROCEDIMIENTO DE PREPARACION CONSISTE EN HACER REACCIONAR COMPUESTOS DE FORMULA (II) Y (III).
CL200400979A 2003-05-09 2004-05-07 Nonapeptidos acilados tipo lysobacitina, composicion que los contiene metodo de preparacion, util como bactericida. CL2004000979A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE10320781A DE10320781A1 (de) 2003-05-09 2003-05-09 Acylierte Nonadepsipeptide

Publications (1)

Publication Number Publication Date
CL2004000979A1 true CL2004000979A1 (es) 2005-05-06

Family

ID=33394366

Family Applications (1)

Application Number Title Priority Date Filing Date
CL200400979A CL2004000979A1 (es) 2003-05-09 2004-05-07 Nonapeptidos acilados tipo lysobacitina, composicion que los contiene metodo de preparacion, util como bactericida.

Country Status (16)

Country Link
US (1) US7368424B2 (es)
EP (1) EP1625153B1 (es)
JP (1) JP4557232B2 (es)
AR (1) AR044256A1 (es)
AT (1) ATE440859T1 (es)
CA (1) CA2524722A1 (es)
CL (1) CL2004000979A1 (es)
DE (2) DE10320781A1 (es)
DK (1) DK1625153T3 (es)
ES (1) ES2330221T3 (es)
GT (1) GT200400090A (es)
PL (1) PL1625153T3 (es)
PT (1) PT1625153E (es)
TW (1) TW200510449A (es)
UY (1) UY28313A1 (es)
WO (1) WO2004099239A1 (es)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10320781A1 (de) * 2003-05-09 2004-11-25 Bayer Healthcare Ag Acylierte Nonadepsipeptide
US7781478B2 (en) 2004-07-14 2010-08-24 Ptc Therapeutics, Inc. Methods for treating hepatitis C
EA200700243A1 (ru) 2004-07-14 2007-08-31 ПиТиСи ТЕРАПЬЮТИКС, ИНК. Способы лечения гепатита с
US7868037B2 (en) 2004-07-14 2011-01-11 Ptc Therapeutics, Inc. Methods for treating hepatitis C
US7772271B2 (en) 2004-07-14 2010-08-10 Ptc Therapeutics, Inc. Methods for treating hepatitis C
EP1781289A1 (en) 2004-07-22 2007-05-09 PTC Therapeutics, Inc. Thienopyridines for treating hepatitis c
DE102004051024A1 (de) * 2004-10-20 2006-04-27 Bayer Healthcare Ag Heterocyclyl-substituierte Nonadepsipeptide
DE102004051023A1 (de) * 2004-10-20 2006-05-04 Bayer Healthcare Ag Desoxo-Nonadepsipeptide
DE102004051025A1 (de) 2004-10-20 2006-04-27 Bayer Healthcare Ag Substituierte Nonadepsipeptide
DE102004053407A1 (de) 2004-11-05 2006-05-11 Bayer Healthcare Ag Acylierte Nonadepsipeptide II
DE102004053410A1 (de) 2004-11-05 2006-05-11 Bayer Healthcare Ag Cyclische Nonadepsipeptidamide
DE102004053409A1 (de) * 2004-11-05 2006-05-11 Bayer Healthcare Ag Verfahren zur gezielten Herstellung von Lysobactinfragmenten
DE102006003443A1 (de) * 2006-01-25 2007-07-26 Aicuris Gmbh & Co. Kg Asparagin-10-substituierte Nonadepsipeptide
DE102006018250A1 (de) * 2006-04-13 2007-10-18 Aicuris Gmbh & Co. Kg Verfahren zum Herstellen von cyclischen Depsipeptiden
DE102006018080A1 (de) * 2006-04-13 2007-10-18 Aicuris Gmbh & Co. Kg Lysobactinamide
JP5564570B2 (ja) * 2009-09-25 2014-07-30 カディラ・ヘルスケア・リミテッド ラコサミドおよびその中間体の調製方法
TW201717991A (zh) * 2015-08-17 2017-06-01 拜耳動物保健有限公司 用於治療牛乳房炎之溶桿菌素
EP3363452A1 (en) 2017-02-17 2018-08-22 Bayer Animal Health GmbH Combinations of lysobactin and aminogylcosides against diseases caused by gram-positive and gram-negative bacteria in non-human animals

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1266247C (en) 1985-03-25 1990-02-27 ANTIBIOTIC PREPARED BY LYSOBACTER SP. SC14.067
JPH01132600A (ja) 1987-11-17 1989-05-25 Shionogi & Co Ltd カタノシンａおよびｂならびにその製造法
DE10320781A1 (de) * 2003-05-09 2004-11-25 Bayer Healthcare Ag Acylierte Nonadepsipeptide

Also Published As

Publication number Publication date
DE502004009971D1 (de) 2009-10-08
JP2007535469A (ja) 2007-12-06
PT1625153E (pt) 2009-11-03
GT200400090A (es) 2004-12-23
DE10320781A1 (de) 2004-11-25
CA2524722A1 (en) 2004-11-18
UY28313A1 (es) 2004-12-31
PL1625153T3 (pl) 2010-02-26
EP1625153A1 (de) 2006-02-15
DK1625153T3 (da) 2009-12-14
JP4557232B2 (ja) 2010-10-06
US7368424B2 (en) 2008-05-06
ATE440859T1 (de) 2009-09-15
ES2330221T3 (es) 2009-12-07
WO2004099239A1 (de) 2004-11-18
TW200510449A (en) 2005-03-16
AR044256A1 (es) 2005-09-07
US20050075281A1 (en) 2005-04-07
EP1625153B1 (de) 2009-08-26

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