CL2007000529A1 - Antigeno vacunal quimerico contra el virus de la peste porcina clasica, vppc, que contiene el segmento extracelular de la glicoproteina e2 de la envoltura viral del vppc y una proteina estimuladora del sistema inmune cd154; composicion que lo comprende. - Google Patents

Antigeno vacunal quimerico contra el virus de la peste porcina clasica, vppc, que contiene el segmento extracelular de la glicoproteina e2 de la envoltura viral del vppc y una proteina estimuladora del sistema inmune cd154; composicion que lo comprende.

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Publication number
CL2007000529A1
CL2007000529A1 CL2007000529A CL2007000529A CL2007000529A1 CL 2007000529 A1 CL2007000529 A1 CL 2007000529A1 CL 2007000529 A CL2007000529 A CL 2007000529A CL 2007000529 A CL2007000529 A CL 2007000529A CL 2007000529 A1 CL2007000529 A1 CL 2007000529A1
Authority
CL
Chile
Prior art keywords
vppc
glycoprotein
composition
immune system
understands
Prior art date
Application number
CL2007000529A
Other languages
English (en)
Inventor
Alonso Jorge Roberto Toledo
Ramos Oliberto Sanchez
Valle Maritza Isidra Barrera
Baile Nancy Elena Figueroa
Carratala Yanet Prieto
Molto Maria Pilar Rodriguez
Lepoureau Maria Teresa Frias
Nordelo Carlos Guillermo Borroto
Original Assignee
Ct Ingenieria Genetica Biotech
Ct Nac De Sanidad Agropecuaria
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ct Ingenieria Genetica Biotech, Ct Nac De Sanidad Agropecuaria filed Critical Ct Ingenieria Genetica Biotech
Publication of CL2007000529A1 publication Critical patent/CL2007000529A1/es

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C07K14/08—RNA viruses
    • C07K14/18—Togaviridae; Flaviviridae
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70575—NGF/TNF-superfamily, e.g. CD70, CD95L, CD153, CD154
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/08—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/10—RNA viruses
    • C07K16/116—Togaviridae (F); Matonaviridae (F); Flaviviridae (F)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K19/00—Hybrid peptides, i.e. peptides covalently bound to nucleic acids, or non-covalently bound protein-protein complexes
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2267/00—Animals characterised by purpose
    • A01K2267/01—Animal expressing industrially exogenous proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/55—Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/55—Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
    • A61K2039/552—Veterinary vaccine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55566—Emulsions, e.g. Freund's adjuvant, MF59
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/57—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
    • A61K2039/6031—Proteins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/20—Fusion polypeptide containing a tag with affinity for a non-protein ligand
    • C07K2319/21—Fusion polypeptide containing a tag with affinity for a non-protein ligand containing a His-tag
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction
    • C07K2319/74—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/10011—Adenoviridae
    • C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
    • C12N2710/10341—Use of virus, viral particle or viral elements as a vector
    • C12N2710/10343—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/24011—Flaviviridae
    • C12N2770/24311—Pestivirus, e.g. bovine viral diarrhea virus
    • C12N2770/24322—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/24011—Flaviviridae
    • C12N2770/24311—Pestivirus, e.g. bovine viral diarrhea virus
    • C12N2770/24334—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Virology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Microbiology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Cell Biology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Treatment Of Fiber Materials (AREA)

Abstract

Antígeno vacunal quimérico contra el virus de la peste porcina clásica, vppc, que contiene el segmento extracelular de la glicoproteína e2 de la envoltura viral del vppc y una proteína estimuladora del sistema inmune; y composición que lo comprende.
CL2007000529A 2006-02-28 2007-02-27 Antigeno vacunal quimerico contra el virus de la peste porcina clasica, vppc, que contiene el segmento extracelular de la glicoproteina e2 de la envoltura viral del vppc y una proteina estimuladora del sistema inmune cd154; composicion que lo comprende. CL2007000529A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CU20060052A CU23544A1 (es) 2006-02-28 2006-02-28 Antígenos vacunales quiméricos contra el virus de la peste porcina clásica

Publications (1)

Publication Number Publication Date
CL2007000529A1 true CL2007000529A1 (es) 2008-01-18

Family

ID=38279009

Family Applications (1)

Application Number Title Priority Date Filing Date
CL2007000529A CL2007000529A1 (es) 2006-02-28 2007-02-27 Antigeno vacunal quimerico contra el virus de la peste porcina clasica, vppc, que contiene el segmento extracelular de la glicoproteina e2 de la envoltura viral del vppc y una proteina estimuladora del sistema inmune cd154; composicion que lo comprende.

Country Status (17)

Country Link
US (1) US8409562B2 (es)
EP (1) EP1994943B1 (es)
JP (1) JP5190383B2 (es)
KR (1) KR101506979B1 (es)
CN (2) CN105214081A (es)
AR (1) AR059648A1 (es)
AT (1) ATE490782T1 (es)
BR (1) BRPI0708354B1 (es)
CA (1) CA2638830C (es)
CL (1) CL2007000529A1 (es)
CU (1) CU23544A1 (es)
DE (1) DE602007011042D1 (es)
ES (1) ES2357563T3 (es)
HK (1) HK1219052A1 (es)
MX (1) MX2008011144A (es)
RU (1) RU2406534C2 (es)
WO (1) WO2007098717A2 (es)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10307475B2 (en) 2009-03-27 2019-06-04 Academia Sinica Methods and compositions for immunization against virus

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TWI362416B (en) * 2008-07-31 2012-04-21 Mao Xing Biolog Technology Co Ltd Yeast expressed classical swine fever virus glycoprotein e2 and use thereof
CN109563518A (zh) * 2016-05-12 2019-04-02 巴伊沃爱普有限公司 来自植物的用于经典猪瘟的疫苗组合物及其制造方法
JP7391997B2 (ja) * 2019-04-25 2023-12-05 アグリカルチュラル テクノロジー リサーチ インスティテュート 豚熱ウイルス感染を予防するための組換えタンパク質、それを含む組成物及び細胞
GB201910794D0 (en) * 2019-07-29 2019-09-11 Pirbright Inst Vaccine
CU20210070A7 (es) * 2021-08-20 2023-03-07 Ct Ingenieria Genetica Biotecnologia Antígenos quiméricos para el control de coronavirus y composiciones que los comprenden
CN114835822B (zh) * 2022-04-22 2022-11-04 浙江洪晟生物科技股份有限公司 猪瘟病毒的多聚体疫苗及其制备方法
CN118126140B (zh) * 2023-04-10 2026-03-27 浙江省农业科学院 一种表达猪瘟病毒e2蛋白的重组伪狂犬病毒株及应用
CU20230025A7 (es) * 2023-05-18 2024-12-09 Ct Ingenieria Genetica Biotecnologia Formulación para la inmunización de cerdos por la vía oral
WO2024235368A1 (es) * 2023-05-18 2024-11-21 Centro De Ingeniería Genética Y Biotecnología Composicion vacunal contra el virus de la peste porcina africana
CN118530369A (zh) * 2024-01-19 2024-08-23 中国农业科学院兰州兽医研究所(中国动物卫生与流行病学中心兰州分中心) 一种猪瘟病毒e2-il28b融合蛋白及其作为抗原在制备猪瘟亚单位疫苗中的应用

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10307475B2 (en) 2009-03-27 2019-06-04 Academia Sinica Methods and compositions for immunization against virus
US11672853B2 (en) 2009-03-27 2023-06-13 Academia Sinica Methods and compositions for immunization against virus

Also Published As

Publication number Publication date
US8409562B2 (en) 2013-04-02
ATE490782T1 (de) 2010-12-15
CA2638830C (en) 2015-04-14
RU2008138536A (ru) 2010-04-10
RU2406534C2 (ru) 2010-12-20
MX2008011144A (es) 2009-01-26
BRPI0708354B1 (pt) 2016-04-19
JP5190383B2 (ja) 2013-04-24
WO2007098717A3 (es) 2007-11-01
HK1219052A1 (zh) 2017-03-24
WO2007098717A2 (es) 2007-09-07
CU23544A1 (es) 2010-06-17
AR059648A1 (es) 2008-04-16
EP1994943A2 (en) 2008-11-26
KR20080111023A (ko) 2008-12-22
BRPI0708354A2 (pt) 2011-05-24
DE602007011042D1 (de) 2011-01-20
KR101506979B1 (ko) 2015-03-30
CN101426525A (zh) 2009-05-06
CA2638830A1 (en) 2007-09-07
JP2009528304A (ja) 2009-08-06
ES2357563T3 (es) 2011-04-27
CN105214081A (zh) 2016-01-06
US20090304633A1 (en) 2009-12-10
EP1994943B1 (en) 2010-12-08

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