CL2007001997A1 - Compuestos derivados de tiofeno, agentes inmunomoduladores; composicion farmaceutica que los comprende; y su uso para tratar o prevenir enfermedades o trastornos asociados con un sistema inmunologico activado, tales como rechazo de organos transplant - Google Patents

Compuestos derivados de tiofeno, agentes inmunomoduladores; composicion farmaceutica que los comprende; y su uso para tratar o prevenir enfermedades o trastornos asociados con un sistema inmunologico activado, tales como rechazo de organos transplant

Info

Publication number: CL2007001997A1
Authority: CL; Chile
Prior art keywords: thiophen; understands; treat; replacement; pharmaceutical composition
Prior art date: 2006-09-07

Application number

CL200701997A

Other languages

English (en)

Inventor

Bolli David Lehmann Bor Martin

Original Assignee

Actelion Pharmaceuticals Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2006-09-07

Filing date

2007-07-09

Publication date

2008-03-07

2007-07-09 Application filed by Actelion Pharmaceuticals Ltd filed Critical Actelion Pharmaceuticals Ltd

2008-03-07 Publication of CL2007001997A1 publication Critical patent/CL2007001997A1/es

Links

208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title 2
YTPLMLYBLZKORZ-UHFFFAOYSA-N Thiophene Chemical compound C=1C=CSC=1 YTPLMLYBLZKORZ-UHFFFAOYSA-N 0.000 title 1
150000001875 compounds Chemical class 0.000 title 1
201000010099 disease Diseases 0.000 title 1
230000001900 immune effect Effects 0.000 title 1
239000002955 immunomodulating agent Substances 0.000 title 1
210000000056 organ Anatomy 0.000 title 1
239000008194 pharmaceutical composition Substances 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
- A61K31/381—Heterocyclic compounds having sulfur as a ring hetero atom having five-membered rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/06—Anti-spasmodics, e.g. drugs for colics, esophagic dyskinesia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/02—Nasal agents, e.g. decongestants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
- A—HUMAN NECESSITIES
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- A61P37/00—Drugs for immunological or allergic disorders
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- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/14—Drugs for disorders of the endocrine system of the thyroid hormones, e.g. T3, T4
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
- C07D333/22—Radicals substituted by doubly bound hetero atoms, or by two hetero atoms other than halogen singly bound to the same carbon atom

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Immunology (AREA)
Diabetes (AREA)
Urology & Nephrology (AREA)
Dermatology (AREA)
Pulmonology (AREA)
Endocrinology (AREA)
Rheumatology (AREA)
Neurology (AREA)
Obesity (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Oncology (AREA)
Transplantation (AREA)
Ophthalmology & Optometry (AREA)
Biomedical Technology (AREA)
Emergency Medicine (AREA)
Neurosurgery (AREA)
Pain & Pain Management (AREA)
Vascular Medicine (AREA)
Hematology (AREA)
Orthopedic Medicine & Surgery (AREA)
Physical Education & Sports Medicine (AREA)
Otolaryngology (AREA)
Epidemiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

CL200701997A 2006-09-07 2007-07-09 Compuestos derivados de tiofeno, agentes inmunomoduladores; composicion farmaceutica que los comprende; y su uso para tratar o prevenir enfermedades o trastornos asociados con un sistema inmunologico activado, tales como rechazo de organos transplant CL2007001997A1 (es)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
IB2006053150		2006-09-07

Publications (1)

Publication Number	Publication Date
CL2007001997A1 true CL2007001997A1 (es)	2008-03-07

Family

ID=38969819

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
CL200701997A CL2007001997A1 (es)	2006-09-07	2007-07-09	Compuestos derivados de tiofeno, agentes inmunomoduladores; composicion farmaceutica que los comprende; y su uso para tratar o prevenir enfermedades o trastornos asociados con un sistema inmunologico activado, tales como rechazo de organos transplant

Country Status (27)

Country	Link
US (1)	US8133910B2 (es)
EP (1)	EP2069322B1 (es)
JP (1)	JP5250555B2 (es)
KR (1)	KR101409560B1 (es)
CN (1)	CN101528726B (es)
AR (1)	AR061841A1 (es)
AU (1)	AU2007293113B2 (es)
BR (1)	BRPI0716482A2 (es)
CA (1)	CA2661102C (es)
CL (1)	CL2007001997A1 (es)
CY (1)	CY1113267T1 (es)
DK (1)	DK2069322T3 (es)
ES (1)	ES2393002T3 (es)
HR (1)	HRP20120962T1 (es)
IL (1)	IL197395A (es)
MA (1)	MA30765B1 (es)
MX (1)	MX2009002227A (es)
MY (1)	MY149869A (es)
NO (1)	NO20091395L (es)
NZ (1)	NZ575979A (es)
PL (1)	PL2069322T3 (es)
PT (1)	PT2069322E (es)
RU (1)	RU2442783C2 (es)
SI (1)	SI2069322T1 (es)
TW (1)	TWI408139B (es)
WO (1)	WO2008029306A2 (es)
ZA (1)	ZA200902391B (es)

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MA34910B1 (fr)	2011-01-19	2014-02-01	Actelion Pharmaceuticals Ltd	Dérivés de 2-methoxy-pyridin-4-yl
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US10111841B2 (en)	2015-06-19	2018-10-30	University Of South Florida	Stabilization of alcohol intoxication-induced cardiovascular instability
BR112017027656B1 (pt)	2015-06-22	2023-12-05	Arena Pharmaceuticals, Inc.	Hábito cristalino de placa livre de sal de l-arginina de ácido (r)-2-(7-(4- ciclopentil-3-(trifluorometil)benzilóxi)- 1,2,3,4-tetra-hidrociclo-penta[b]indol-3- il)acético, composição farmacêutica que o compreende, seus usos e método de preparação do mesmo
MX2019009841A (es)	2017-02-16	2020-01-30	Arena Pharm Inc	Compuestos y metodos para el tratamiento de la colangitis biliar primaria.
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2007
- 2007-07-06 AR ARP070103032A patent/AR061841A1/es unknown
- 2007-07-06 TW TW096124719A patent/TWI408139B/zh not_active IP Right Cessation
- 2007-07-09 CL CL200701997A patent/CL2007001997A1/es unknown
- 2007-07-10 ES ES07789922T patent/ES2393002T3/es active Active
- 2007-07-10 BR BRPI0716482-3A patent/BRPI0716482A2/pt not_active IP Right Cessation
- 2007-07-10 WO PCT/IB2007/052742 patent/WO2008029306A2/en not_active Ceased
- 2007-07-10 EP EP07789922A patent/EP2069322B1/en not_active Not-in-force
- 2007-07-10 RU RU2009112536/04A patent/RU2442783C2/ru not_active IP Right Cessation
- 2007-07-10 PT PT07789922T patent/PT2069322E/pt unknown
- 2007-07-10 CA CA2661102A patent/CA2661102C/en not_active Expired - Fee Related
- 2007-07-10 AU AU2007293113A patent/AU2007293113B2/en not_active Ceased
- 2007-07-10 US US12/310,762 patent/US8133910B2/en not_active Expired - Fee Related
- 2007-07-10 HR HRP20120962TT patent/HRP20120962T1/hr unknown
- 2007-07-10 DK DK07789922.7T patent/DK2069322T3/da active
- 2007-07-10 JP JP2009527231A patent/JP5250555B2/ja not_active Expired - Fee Related
- 2007-07-10 PL PL07789922T patent/PL2069322T3/pl unknown
- 2007-07-10 MY MYPI20090911A patent/MY149869A/en unknown
- 2007-07-10 KR KR1020097006864A patent/KR101409560B1/ko not_active Expired - Fee Related
- 2007-07-10 SI SI200731060T patent/SI2069322T1/sl unknown
- 2007-07-10 NZ NZ575979A patent/NZ575979A/en not_active IP Right Cessation
- 2007-07-10 CN CN2007800333953A patent/CN101528726B/zh not_active Expired - Fee Related
- 2007-07-10 MX MX2009002227A patent/MX2009002227A/es active IP Right Grant
2009
- 2009-03-04 IL IL197395A patent/IL197395A/en not_active IP Right Cessation
- 2009-03-18 MA MA31727A patent/MA30765B1/fr unknown
- 2009-04-06 ZA ZA2009/02391A patent/ZA200902391B/en unknown
- 2009-04-06 NO NO20091395A patent/NO20091395L/no not_active Application Discontinuation
2012
- 2012-10-31 CY CY20121101041T patent/CY1113267T1/el unknown

Also Published As

Publication number	Publication date
AR061841A1 (es)	2008-09-24
ES2393002T3 (es)	2012-12-17
EP2069322B1 (en)	2012-09-12
HRP20120962T1 (hr)	2012-12-31
AU2007293113B2 (en)	2013-02-14
IL197395A0 (en)	2009-12-24
KR20090059144A (ko)	2009-06-10
CN101528726B (zh)	2012-11-14
PL2069322T3 (pl)	2013-02-28
RU2009112536A (ru)	2010-10-20
ZA200902391B (en)	2015-08-26
NO20091395L (no)	2009-04-06
EP2069322A2 (en)	2009-06-17
AU2007293113A1 (en)	2008-03-13
US8133910B2 (en)	2012-03-13
US20100048648A1 (en)	2010-02-25
TWI408139B (zh)	2013-09-11
HK1134294A1 (en)	2010-04-23
MA30765B1 (fr)	2009-10-01
CA2661102C (en)	2014-10-14
DK2069322T3 (da)	2012-11-05
KR101409560B1 (ko)	2014-06-19
RU2442783C2 (ru)	2012-02-20
PT2069322E (pt)	2012-11-21
MX2009002227A (es)	2009-03-16
WO2008029306A3 (en)	2008-05-15
CY1113267T1 (el)	2016-04-13
BRPI0716482A2 (pt)	2013-03-12
TW200813044A (en)	2008-03-16
MY149869A (en)	2013-10-31
CN101528726A (zh)	2009-09-09
IL197395A (en)	2014-06-30
JP2010502693A (ja)	2010-01-28
JP5250555B2 (ja)	2013-07-31
SI2069322T1 (sl)	2012-12-31
WO2008029306A2 (en)	2008-03-13
CA2661102A1 (en)	2008-03-13
NZ575979A (en)	2012-02-24

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