CL2007003169A1 - Compuestos derivados del acido l-glutamico marcado con f-18; procedimiento de preparacion; compuestos intermediarios; procedimiento para preparar los compuestos intermediarios; utiles como agentes de diagnostico. - Google Patents
Compuestos derivados del acido l-glutamico marcado con f-18; procedimiento de preparacion; compuestos intermediarios; procedimiento para preparar los compuestos intermediarios; utiles como agentes de diagnostico.Info
- Publication number
- CL2007003169A1 CL2007003169A1 CL200703169A CL2007003169A CL2007003169A1 CL 2007003169 A1 CL2007003169 A1 CL 2007003169A1 CL 200703169 A CL200703169 A CL 200703169A CL 2007003169 A CL2007003169 A CL 2007003169A CL 2007003169 A1 CL2007003169 A1 CL 2007003169A1
- Authority
- CL
- Chile
- Prior art keywords
- compounds
- procedure
- useful
- glutamic acid
- diagnostic agents
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/0402—Organic compounds carboxylic acid carriers, fatty acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B59/00—Introduction of isotopes of elements into organic compounds ; Labelled organic compounds per se
- C07B59/001—Acyclic or carbocyclic compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C227/14—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof
- C07C227/16—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof by reactions not involving the amino or carboxyl groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C229/04—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
- C07C229/24—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having more than one carboxyl group bound to the carbon skeleton, e.g. aspartic acid
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C251/00—Compounds containing nitrogen atoms doubly-bound to a carbon skeleton
- C07C251/02—Compounds containing nitrogen atoms doubly-bound to a carbon skeleton containing imino groups
- C07C251/24—Compounds containing nitrogen atoms doubly-bound to a carbon skeleton containing imino groups having carbon atoms of imino groups bound to carbon atoms of six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
- C07C271/06—Esters of carbamic acids
- C07C271/08—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
- C07C271/10—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C271/22—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of hydrocarbon radicals substituted by carboxyl groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C309/00—Sulfonic acids; Halides, esters, or anhydrides thereof
- C07C309/63—Esters of sulfonic acids
- C07C309/64—Esters of sulfonic acids having sulfur atoms of esterified sulfo groups bound to acyclic carbon atoms
- C07C309/65—Esters of sulfonic acids having sulfur atoms of esterified sulfo groups bound to acyclic carbon atoms of a saturated carbon skeleton
- C07C309/66—Methanesulfonates
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C309/00—Sulfonic acids; Halides, esters, or anhydrides thereof
- C07C309/63—Esters of sulfonic acids
- C07C309/72—Esters of sulfonic acids having sulfur atoms of esterified sulfo groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
- C07C309/73—Esters of sulfonic acids having sulfur atoms of esterified sulfo groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton to carbon atoms of non-condensed six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/16—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/24—Oxygen or sulfur atoms
- C07D207/26—2-Pyrrolidones
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/24—Oxygen or sulfur atoms
- C07D207/26—2-Pyrrolidones
- C07D207/273—2-Pyrrolidones with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to other ring carbon atoms
- C07D207/277—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D207/28—2-Pyrrolidone-5- carboxylic acids; Functional derivatives thereof, e.g. esters, nitriles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F15/00—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
- C07F15/04—Nickel compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F15/00—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
- C07F15/04—Nickel compounds
- C07F15/045—Nickel compounds without a metal-carbon linkage
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/05—Isotopically modified compounds, e.g. labelled
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Physics & Mathematics (AREA)
- Optics & Photonics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| RU2006138584/04A RU2395489C2 (ru) | 2006-11-01 | 2006-11-01 | [f-18] меченная l-глютаминовая кислота, [f-18] меченный l-глютамин, их производные и их применение, а также способ их получения |
| EP06090211A EP1923382A1 (de) | 2006-11-18 | 2006-11-18 | [F-18] markierte L-Glutaminsäure, [F-18] markiertes Glutamin, ihre Derivate und ihre Verwendung sowie Verfahren zu ihrer Herstellung |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CL2007003169A1 true CL2007003169A1 (es) | 2008-07-04 |
Family
ID=38896929
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CL200703169A CL2007003169A1 (es) | 2006-11-01 | 2007-11-02 | Compuestos derivados del acido l-glutamico marcado con f-18; procedimiento de preparacion; compuestos intermediarios; procedimiento para preparar los compuestos intermediarios; utiles como agentes de diagnostico. |
| CL2012000768A CL2012000768A1 (es) | 2006-11-01 | 2012-03-28 | Compuestos derivados de acido l-glutamico y l-glutamina marcados con [18f]; procedimiento de preparacion; y su uso para el diagnostico de enfermedades tumorales. |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CL2012000768A CL2012000768A1 (es) | 2006-11-01 | 2012-03-28 | Compuestos derivados de acido l-glutamico y l-glutamina marcados con [18f]; procedimiento de preparacion; y su uso para el diagnostico de enfermedades tumorales. |
Country Status (23)
| Country | Link |
|---|---|
| US (2) | US20100217011A1 (es) |
| EP (1) | EP2086924B1 (es) |
| JP (4) | JP5529540B2 (es) |
| KR (1) | KR101495924B1 (es) |
| CN (1) | CN101595083B (es) |
| AR (1) | AR071043A1 (es) |
| AU (1) | AU2007315203B2 (es) |
| BR (1) | BRPI0718055A2 (es) |
| CA (1) | CA2667395C (es) |
| CL (2) | CL2007003169A1 (es) |
| CO (1) | CO6180453A2 (es) |
| CU (1) | CU23825B1 (es) |
| EA (1) | EA017713B1 (es) |
| EC (1) | ECSP099304A (es) |
| ES (1) | ES2701423T3 (es) |
| IL (1) | IL198022A0 (es) |
| MX (1) | MX2009004686A (es) |
| NO (1) | NO20092123L (es) |
| NZ (1) | NZ576582A (es) |
| PE (1) | PE20091723A1 (es) |
| SV (1) | SV2009003251A (es) |
| TW (1) | TWI415626B (es) |
| WO (1) | WO2008052788A1 (es) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR101495924B1 (ko) | 2006-11-01 | 2015-02-25 | 바이엘 파마 악티엔게젤샤프트 | [f-18]-표지된 l-글루탐산, [f-18]-표지된 l-글루타민, 이들의 유도체 및 이들의 용도 및 이들의 제조 방법 |
| EP2123621A1 (de) * | 2008-05-20 | 2009-11-25 | Bayer Schering Pharma Aktiengesellschaft | Neue {F-18}-markierte L-Glutaminsäure- und L-Glutaminderivate (I), ihre Verwendung sowie Verfahren zu ihrer Herstellung |
| EP2123619A1 (de) * | 2008-05-20 | 2009-11-25 | Bayer Schering Pharma AG | Neue [F-18]-Markierte L-Glutaminsäure-und L-Glutaminderivate (II), ihre Verwendung sowie Verfahren zu ihrer Herstellung |
| EP2123620A1 (en) * | 2008-05-20 | 2009-11-25 | Bayer Schering Pharma Aktiengesellschaft | {F-19}-labeled L-Glutamic acid and L-Glutamine derivative (III), use thereof and method for obtaining them |
| SG195545A1 (en) | 2008-10-10 | 2013-12-30 | Merck & Cie | 18f-labelled folates as pet radiotracers |
| US8722014B2 (en) * | 2009-05-01 | 2014-05-13 | Washington University | 1 H-[1, 2, 3] triazole substituted amino acids and uses thereof |
| JP2013501813A (ja) * | 2009-08-14 | 2013-01-17 | ザ・トラスティーズ・オブ・ザ・ユニバーシティ・オブ・ペンシルバニア | 4−フルオログルタミンの単一ジアステレオマーおよびその調製法と利用 |
| MX2012005733A (es) * | 2009-11-17 | 2013-01-22 | Bayer Ip Gmbh | Metodo de produccion de derivados de acido glutamico marcados con f-18. |
| EP2322171A3 (en) * | 2009-11-17 | 2011-06-01 | Bayer Schering Pharma Aktiengesellschaft | Fluorine labeled L-glutamic acid derivatives |
| WO2011061154A1 (en) * | 2009-11-17 | 2011-05-26 | Bayer Schering Pharma Aktiengesellschaft | Iodine-labeled homoglutamic acid and glutamic acid derivatives |
| EP2338892A1 (en) * | 2009-12-18 | 2011-06-29 | Bayer Schering Pharma Aktiengesellschaft | Prostate specific membrane antigen inhibitors |
| WO2012092394A1 (en) | 2010-12-29 | 2012-07-05 | Cardinal Health 414, Llc | Closed vial fill system for aseptic dispensing |
| EP2520557A1 (en) * | 2011-05-03 | 2012-11-07 | Bayer Pharma Aktiengesellschaft | Novel precursors of glutamate derivatives |
| EP2520556A1 (en) | 2011-05-03 | 2012-11-07 | Bayer Pharma Aktiengesellschaft | Radiolabeled amino acids for diagnostic imaging |
| WO2013012822A1 (en) | 2011-07-15 | 2013-01-24 | Cardinal Health 414, Llc | Systems, methods, and devices for producing, manufacturing, and control of radiopharmaceuticals |
| US20130022525A1 (en) * | 2011-07-15 | 2013-01-24 | Cardinal Health 414, Llc | Methods and compositions for drying in the preparation of radiopharmaceuticals |
| US20130020727A1 (en) | 2011-07-15 | 2013-01-24 | Cardinal Health 414, Llc. | Modular cassette synthesis unit |
| US9417332B2 (en) | 2011-07-15 | 2016-08-16 | Cardinal Health 414, Llc | Radiopharmaceutical CZT sensor and apparatus |
| WO2020010228A1 (en) * | 2018-07-06 | 2020-01-09 | The Regents Of The University Of California | Deconstructive functionalization methods and compounds |
| CN109369445B (zh) * | 2018-11-20 | 2021-10-15 | 首都医科大学 | 用于诊断和治疗的放射性谷氨酰胺衍生物及其制备方法 |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR1461184A (fr) * | 1964-12-23 | 1966-01-07 | Takeda Chemical Industries Ltd | Procédé de préparation d'isoxazolidones substituées en position 5 |
| DE1620522A1 (de) * | 1964-12-23 | 1970-04-23 | Takeda Chemical Industries Ltd | Verfahren zur Herstellung von 5-substituierten Isoxazolidonverbindungen |
| US5264570A (en) * | 1992-08-05 | 1993-11-23 | General Electric Company | Method for making 2-[18 F]fluoro-2-deoxy-D-glucose |
| US5267570A (en) * | 1992-12-30 | 1993-12-07 | Preston Myra S | Method of diagnosing and treating chronic fatigue syndrome |
| GB9324872D0 (en) | 1993-12-03 | 1994-01-19 | Univ Pasteur | Pharmaceutical compounds |
| IL145712A0 (en) * | 1999-04-01 | 2002-07-25 | Esperion Therapeutics Inc | Ether compounds, compositions, and uses thereof |
| WO2002014261A2 (en) | 2000-08-10 | 2002-02-21 | Eli Lilly And Company | 4-substituted d-glutamic acid derivatives for use as antibiotic |
| CA2421507A1 (en) * | 2000-09-01 | 2002-03-07 | Karina Aprico | Screen for glutamate reuptake inhibitors, stimulators, and modulators |
| DE10223451A1 (de) * | 2002-05-25 | 2003-12-24 | Abx Gmbh | Verfahren zur Herstellung von 18F-fluorierten alpha-Aminosäuren |
| JP2006516547A (ja) * | 2002-08-02 | 2006-07-06 | マリンクロッド・インコーポレイテッド | 放射性標識アミノ酸類似体、それらの製造および使用 |
| DE10346228B4 (de) * | 2003-09-25 | 2009-04-09 | Eberhard-Karls-Universität Tübingen Universitätsklinikum | Herstellung von [18F]fluormarkierten aromatischen L-Aminosäuren |
| US7270799B2 (en) * | 2004-01-15 | 2007-09-18 | Nst Neurosurvival Technologies Ltd. | Perturbed membrane-binding compounds and methods of using the same |
| US7483732B2 (en) * | 2004-04-15 | 2009-01-27 | Boston Scientific Scimed, Inc. | Magnetic resonance imaging of a medical device and proximate body tissue |
| US20070011016A1 (en) * | 2005-07-07 | 2007-01-11 | Alderman Joseph B | Springing interests flowing from benefits that run with land |
| EP2123621A1 (de) | 2008-05-20 | 2009-11-25 | Bayer Schering Pharma Aktiengesellschaft | Neue {F-18}-markierte L-Glutaminsäure- und L-Glutaminderivate (I), ihre Verwendung sowie Verfahren zu ihrer Herstellung |
| EP1923382A1 (de) | 2006-11-18 | 2008-05-21 | Bayer Schering Pharma Aktiengesellschaft | [F-18] markierte L-Glutaminsäure, [F-18] markiertes Glutamin, ihre Derivate und ihre Verwendung sowie Verfahren zu ihrer Herstellung |
| KR101495924B1 (ko) | 2006-11-01 | 2015-02-25 | 바이엘 파마 악티엔게젤샤프트 | [f-18]-표지된 l-글루탐산, [f-18]-표지된 l-글루타민, 이들의 유도체 및 이들의 용도 및 이들의 제조 방법 |
| EP2123619A1 (de) * | 2008-05-20 | 2009-11-25 | Bayer Schering Pharma AG | Neue [F-18]-Markierte L-Glutaminsäure-und L-Glutaminderivate (II), ihre Verwendung sowie Verfahren zu ihrer Herstellung |
| EP2123620A1 (en) | 2008-05-20 | 2009-11-25 | Bayer Schering Pharma Aktiengesellschaft | {F-19}-labeled L-Glutamic acid and L-Glutamine derivative (III), use thereof and method for obtaining them |
-
2007
- 2007-10-30 KR KR20097009017A patent/KR101495924B1/ko not_active Expired - Fee Related
- 2007-10-30 AU AU2007315203A patent/AU2007315203B2/en not_active Ceased
- 2007-10-30 CN CN200780040971.7A patent/CN101595083B/zh not_active Expired - Fee Related
- 2007-10-30 EA EA200970428A patent/EA017713B1/ru not_active IP Right Cessation
- 2007-10-30 MX MX2009004686A patent/MX2009004686A/es active IP Right Grant
- 2007-10-30 NZ NZ576582A patent/NZ576582A/en not_active IP Right Cessation
- 2007-10-30 EP EP07819544.3A patent/EP2086924B1/de active Active
- 2007-10-30 ES ES07819544T patent/ES2701423T3/es active Active
- 2007-10-30 JP JP2009535027A patent/JP5529540B2/ja not_active Expired - Fee Related
- 2007-10-30 BR BRPI0718055-1A2A patent/BRPI0718055A2/pt not_active IP Right Cessation
- 2007-10-30 US US12/513,112 patent/US20100217011A1/en not_active Abandoned
- 2007-10-30 WO PCT/EP2007/009518 patent/WO2008052788A1/de not_active Ceased
- 2007-10-30 CA CA2667395A patent/CA2667395C/en not_active Expired - Fee Related
- 2007-11-01 TW TW096141249A patent/TWI415626B/zh not_active IP Right Cessation
- 2007-11-01 AR ARP070104863A patent/AR071043A1/es not_active Application Discontinuation
- 2007-11-02 CL CL200703169A patent/CL2007003169A1/es unknown
-
2008
- 2008-04-23 PE PE2008000696A patent/PE20091723A1/es not_active Application Discontinuation
-
2009
- 2009-04-06 IL IL198022A patent/IL198022A0/en unknown
- 2009-04-30 EC EC2009009304A patent/ECSP099304A/es unknown
- 2009-04-30 CO CO09043963A patent/CO6180453A2/es not_active Application Discontinuation
- 2009-04-30 SV SV2009003251A patent/SV2009003251A/es unknown
- 2009-05-04 CU CU20090072A patent/CU23825B1/es not_active IP Right Cessation
- 2009-05-29 NO NO20092123A patent/NO20092123L/no not_active Application Discontinuation
-
2012
- 2012-03-28 CL CL2012000768A patent/CL2012000768A1/es unknown
-
2013
- 2013-12-02 JP JP2013249417A patent/JP5815651B2/ja not_active Expired - Fee Related
- 2013-12-02 JP JP2013249418A patent/JP2014088389A/ja active Pending
-
2014
- 2014-01-13 US US14/153,491 patent/US9375497B2/en not_active Expired - Fee Related
- 2014-06-10 JP JP2014119836A patent/JP5749836B2/ja not_active Expired - Fee Related
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ECSP11011517A (es) | Compuestos antivirales | |
| CL2007003671A1 (es) | Metodo para la preparacion de derivados del acido 2-amino-5-cianobenzoico, utiles como intermediarios para la preparacion de las correspondientes diamidas cianoantranilicas. | |
| PT2121578T (pt) | Processo de preparação de ácido 5-bifenil-4-amino-2-metil-pentanoico | |
| EP2552216A4 (en) | DERIVATIVES OF 1-AMINO-2-CYCLOPROPYLETHYLBORONIC ACID | |
| BRPI0918838A2 (pt) | processos para preparação de composições de polipeptídeos purificados | |
| CR20120264A (es) | Compuestos | |
| NI201400081A (es) | Nuevos derivados de indolizina , su procedimiento de preparación y las composiciones farmacéuticas que los contienen. | |
| BR112013002925A2 (pt) | processo para a síntese de ácido 2,5-furandicarboxílico | |
| DK2220021T3 (da) | Fremgangsmåde til fremstilling af terephtalsyre | |
| BR112014002922A2 (pt) | compostos da fórmula i, processo de preparação de compostos da fórmula i, compostos da formula xii, viii e xi, composições agroquímicas, uso e semente | |
| BRPI0910112A2 (pt) | Preparação de oligossacarídeo de (arabino)xilano | |
| CO6491116A2 (es) | Derivados de 5-fluoropirimidinona | |
| MX388468B (es) | Compuestos multicíclicos y métodos de uso de los mismos. | |
| BRPI1008939A2 (pt) | 2-mercaptoquinolina-3-carboxamidas substituídas como moduladores de kncq2/3. | |
| CO6950507A2 (es) | Compuestos de 1,2,5-oxadiazoly su uso como herbicidas ii | |
| EP2130549A4 (en) | SOLID FIBRINOGEN PREPARATION | |
| CU20090072A7 (es) | Ácido l-glutámico marcado con [f-18], l-glutamina marcada con [f-18], sus derivados y su uso, así como procedimientos para su preparación | |
| SV2009003429A (es) | Derivados de 7-alquinil-1,8-naftiridonas, su preparacion y su aplicacion en terapeutica | |
| ECSP12011653A (es) | Derivados de n1-acil-5-fluoropirimidinona | |
| DK2513063T3 (da) | Fremgangsmåde til fremstilling af 1-alkyl-/1-aryl-5-pyrazolcarboxylsyrederivater | |
| UY34612A (es) | ?procedimiento para la preparación de derivados de isoxazolina azetidina quirales como agentes antiparasitarios?. | |
| CL2007003875A1 (es) | Compuestos derivados de amidas del acido 3-amino tetrahidrofurano-3-carboxilico; procedimiento de preparacion de dichos compuestos. | |
| CO7020857A2 (es) | Procedimiento para la preparación de complejos de 68ga | |
| CO6321246A2 (es) | Compuestos novedosos activos como antagonistas de receptor muscarinico | |
| BRPI0815673A2 (pt) | Sulfonas cíclicas substituídas por aminobenzila úteis como inibidores de bace. |