CL2009001370A1 - Formas cristalinas de (r,s)-, (r)- y (s)-dopc; proceso de preparacion; composicion farmaceutica; y su uso para preparar medicamentos. - Google Patents

Formas cristalinas de (r,s)-, (r)- y (s)-dopc; proceso de preparacion; composicion farmaceutica; y su uso para preparar medicamentos.

Info

Publication number
CL2009001370A1
CL2009001370A1 CL2009001370A CL2009001370A CL2009001370A1 CL 2009001370 A1 CL2009001370 A1 CL 2009001370A1 CL 2009001370 A CL2009001370 A CL 2009001370A CL 2009001370 A CL2009001370 A CL 2009001370A CL 2009001370 A1 CL2009001370 A1 CL 2009001370A1
Authority
CL
Chile
Prior art keywords
dopc
pharmaceutical composition
preparation process
crystalline forms
prepare medicines
Prior art date
Application number
CL2009001370A
Other languages
English (en)
Inventor
Michael Platscher
Alfred Hedinger
Original Assignee
Merck Eprova Ag
Merck Patent Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=40227929&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CL2009001370(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Merck Eprova Ag, Merck Patent Gmbh filed Critical Merck Eprova Ag
Publication of CL2009001370A1 publication Critical patent/CL2009001370A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/06—Phosphorus compounds without P—C bonds
    • C07F9/08—Esters of oxyacids of phosphorus
    • C07F9/09—Esters of phosphoric acids
    • C07F9/10—Phosphatides, e.g. lecithin
    • C07F9/103—Extraction or purification by physical or chemical treatment of natural phosphatides; Preparation of compositions containing phosphatides of unknown structure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/24—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C30—CRYSTAL GROWTH
    • C30B—SINGLE-CRYSTAL GROWTH; UNIDIRECTIONAL SOLIDIFICATION OF EUTECTIC MATERIAL OR UNIDIRECTIONAL DEMIXING OF EUTECTOID MATERIAL; REFINING BY ZONE-MELTING OF MATERIAL; PRODUCTION OF A HOMOGENEOUS POLYCRYSTALLINE MATERIAL WITH DEFINED STRUCTURE; SINGLE CRYSTALS OR HOMOGENEOUS POLYCRYSTALLINE MATERIAL WITH DEFINED STRUCTURE; AFTER-TREATMENT OF SINGLE CRYSTALS OR A HOMOGENEOUS POLYCRYSTALLINE MATERIAL WITH DEFINED STRUCTURE; APPARATUS THEREFOR
    • C30B29/00—Single crystals or homogeneous polycrystalline material with defined structure characterised by the material or by their shape
    • C30B29/54—Organic compounds
    • C30B29/58—Macromolecular compounds
    • C—CHEMISTRY; METALLURGY
    • C30—CRYSTAL GROWTH
    • C30B—SINGLE-CRYSTAL GROWTH; UNIDIRECTIONAL SOLIDIFICATION OF EUTECTIC MATERIAL OR UNIDIRECTIONAL DEMIXING OF EUTECTOID MATERIAL; REFINING BY ZONE-MELTING OF MATERIAL; PRODUCTION OF A HOMOGENEOUS POLYCRYSTALLINE MATERIAL WITH DEFINED STRUCTURE; SINGLE CRYSTALS OR HOMOGENEOUS POLYCRYSTALLINE MATERIAL WITH DEFINED STRUCTURE; AFTER-TREATMENT OF SINGLE CRYSTALS OR A HOMOGENEOUS POLYCRYSTALLINE MATERIAL WITH DEFINED STRUCTURE; APPARATUS THEREFOR
    • C30B7/00—Single-crystal growth from solutions using solvents which are liquid at normal temperature, e.g. aqueous solutions
    • C30B7/08—Single-crystal growth from solutions using solvents which are liquid at normal temperature, e.g. aqueous solutions by cooling of the solution

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Materials Engineering (AREA)
  • Epidemiology (AREA)
  • Metallurgy (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dispersion Chemistry (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Alótropos cristalinos estables de (r,s)-, (r)- y (s)-dopc, procedimiento para prepararlos, composición farmacéutica que los contiene y su uso para preparar medicamentos.
CL2009001370A 2008-06-06 2009-06-05 Formas cristalinas de (r,s)-, (r)- y (s)-dopc; proceso de preparacion; composicion farmaceutica; y su uso para preparar medicamentos. CL2009001370A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP08010331 2008-06-06

Publications (1)

Publication Number Publication Date
CL2009001370A1 true CL2009001370A1 (es) 2010-06-25

Family

ID=40227929

Family Applications (1)

Application Number Title Priority Date Filing Date
CL2009001370A CL2009001370A1 (es) 2008-06-06 2009-06-05 Formas cristalinas de (r,s)-, (r)- y (s)-dopc; proceso de preparacion; composicion farmaceutica; y su uso para preparar medicamentos.

Country Status (19)

Country Link
US (1) US8513446B2 (es)
EP (1) EP2280691B1 (es)
JP (2) JP5947541B2 (es)
KR (2) KR20160047597A (es)
CN (1) CN102056592B (es)
AU (1) AU2009254310B2 (es)
BR (1) BRPI0913347B1 (es)
CA (1) CA2726871C (es)
CL (1) CL2009001370A1 (es)
DK (1) DK2280691T3 (es)
ES (1) ES2933098T3 (es)
IL (1) IL209476A (es)
MX (1) MX2010013246A (es)
NZ (1) NZ590274A (es)
PT (1) PT2280691T (es)
RU (1) RU2543046C2 (es)
TW (1) TWI458501B (es)
WO (1) WO2009146779A1 (es)
ZA (1) ZA201100141B (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX2010013246A (es) * 2008-06-06 2010-12-21 Merck Patent Gmbh Alotropos cristalinos estables de dopc.
WO2025084317A1 (ja) * 2023-10-16 2025-04-24 国立大学法人北海道大学 双性イオンリン脂質化合物及びそれを含む脂質ナノ粒子

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2647395C2 (de) 1976-10-20 1984-03-29 A. Nattermann & Cie GmbH, 5000 Köln Verfahren zur Herstellung von Estern des Glycerophosphocholins
RU2295954C2 (ru) * 2000-09-28 2007-03-27 Чирон Корпорейшн Микрочастицы для доставки гетерологичных нуклеиновых кислот
US7968115B2 (en) * 2004-03-05 2011-06-28 Board Of Regents, The University Of Texas System Liposomal curcumin for treatment of cancer
AU2005302255A1 (en) * 2004-10-28 2006-05-11 Alza Corporation Lyophilized liposome formulations and method
GB0803969D0 (en) * 2008-03-04 2008-04-09 Britannia Pharmaceuticals Ltd Improved phospholipid and method for its production
MX2010013246A (es) * 2008-06-06 2010-12-21 Merck Patent Gmbh Alotropos cristalinos estables de dopc.

Also Published As

Publication number Publication date
KR101820967B1 (ko) 2018-01-22
IL209476A (en) 2016-08-31
AU2009254310B2 (en) 2014-05-22
US20110086091A1 (en) 2011-04-14
RU2010154508A (ru) 2012-07-20
KR20160047597A (ko) 2016-05-02
JP2015013867A (ja) 2015-01-22
WO2009146779A1 (de) 2009-12-10
RU2543046C2 (ru) 2015-02-27
KR20110022660A (ko) 2011-03-07
ZA201100141B (en) 2011-10-26
NZ590274A (en) 2012-07-27
CA2726871A1 (en) 2009-12-10
CA2726871C (en) 2016-10-11
DK2280691T3 (da) 2022-10-31
PT2280691T (pt) 2022-10-28
MX2010013246A (es) 2010-12-21
CN102056592A (zh) 2011-05-11
AU2009254310A1 (en) 2009-12-10
CN102056592B (zh) 2013-03-27
US8513446B2 (en) 2013-08-20
JP5947541B2 (ja) 2016-07-06
ES2933098T3 (es) 2023-02-01
JP5972323B2 (ja) 2016-08-17
TWI458501B (zh) 2014-11-01
BRPI0913347A2 (pt) 2015-11-24
TW201012485A (en) 2010-04-01
EP2280691B1 (de) 2022-08-03
EP2280691A1 (de) 2011-02-09
BRPI0913347B1 (pt) 2023-11-21
IL209476A0 (en) 2011-01-31
JP2011523951A (ja) 2011-08-25

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