CL2011001178A1 - Uso de (r)-7-cloro-niquinuclidin-3-1l)senzo[b]tiofen0-2-carboxamida o una sal de la misma o una composicion farmaceutica que la comprende para preparar un medicamento util para mejorar la cognicion en un paciente que sufre de alzheimer o esquizofrenia. - Google Patents

Uso de (r)-7-cloro-niquinuclidin-3-1l)senzo[b]tiofen0-2-carboxamida o una sal de la misma o una composicion farmaceutica que la comprende para preparar un medicamento util para mejorar la cognicion en un paciente que sufre de alzheimer o esquizofrenia.

Info

Publication number: CL2011001178A1
Authority: CL; Chile
Prior art keywords: carboxamide; thiophene; chloro; salt; niquinuclidin
Prior art date: 2008-11-19

Application number

CL2011001178A

Other languages

English (en)

Spanish (es)

Inventor

Gerhard Koenig

Richard Chesworth

Gideon Shapiro

Original Assignee

Forum Pharmaceuticals Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2008-11-19

Filing date

2011-05-19

Publication date

2011-10-14

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=41786120&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CL2011001178(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2011-05-19 Application filed by Forum Pharmaceuticals Inc filed Critical Forum Pharmaceuticals Inc

2011-10-14 Publication of CL2011001178A1 publication Critical patent/CL2011001178A1/es

Links

230000019771 cognition Effects 0.000 title abstract 2
150000003839 salts Chemical class 0.000 title abstract 2
229940079593 drug Drugs 0.000 title 1
239000003814 drug Substances 0.000 title 1
239000008194 pharmaceutical composition Substances 0.000 title 1
201000000980 schizophrenia Diseases 0.000 title 1
DENPQNAWGQXKCU-UHFFFAOYSA-N thiophene-2-carboxamide Chemical compound NC(=O)C1=CC=CS1 DENPQNAWGQXKCU-UHFFFAOYSA-N 0.000 title 1
SSRDSYXGYPJKRR-ZDUSSCGKSA-N n-[(3r)-1-azabicyclo[2.2.2]octan-3-yl]-7-chloro-1-benzothiophene-2-carboxamide Chemical compound C1N(CC2)CCC2[C@H]1NC(=O)C1=CC(C=CC=C2Cl)=C2S1 SSRDSYXGYPJKRR-ZDUSSCGKSA-N 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/439—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom the ring forming part of a bridged ring system, e.g. quinuclidine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4406—Non condensed pyridines; Hydrogenated derivatives thereof only substituted in position 3, e.g. zimeldine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4462—Non condensed piperidines, e.g. piperocaine only substituted in position 3
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2121/00—Preparations for use in therapy

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Epidemiology (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
Psychiatry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

CL2011001178A 2008-11-19 2011-05-19 Uso de (r)-7-cloro-niquinuclidin-3-1l)senzo[b]tiofen0-2-carboxamida o una sal de la misma o una composicion farmaceutica que la comprende para preparar un medicamento util para mejorar la cognicion en un paciente que sufre de alzheimer o esquizofrenia. CL2011001178A1 (es)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US11610608P	2008-11-19	2008-11-19

Publications (1)

Publication Number	Publication Date
CL2011001178A1 true CL2011001178A1 (es)	2011-10-14

Family

ID=41786120

Family Applications (3)

Application Number	Title	Priority Date	Filing Date
CL2011001178A CL2011001178A1 (es)	2008-11-19	2011-05-19	Uso de (r)-7-cloro-niquinuclidin-3-1l)senzo[b]tiofen0-2-carboxamida o una sal de la misma o una composicion farmaceutica que la comprende para preparar un medicamento util para mejorar la cognicion en un paciente que sufre de alzheimer o esquizofrenia.
CL2017001853A CL2017001853A1 (es)	2008-11-19	2017-07-18	Tratamiento de trastornos cognitivos con (r)-7-cloro-n-(quinuclidin-3-il)benzo[b]tiofeno-2-carboxamida y sales farmacéuticamente aceptables de la misma (divisional de solicitud n°1707-2016).
CL2018001420A CL2018001420A1 (es)	2008-11-19	2018-05-25	Tratamiento de trastornos cognitivos con (r)-7-cloro-n-(quinuclidin-3-il)benzo[b]tiofeno-2-carboxamida y sales farmacéuticamente aceptables de la misma. (divisional solicitud 201701853)

Family Applications After (2)

Application Number	Title	Priority Date	Filing Date
CL2017001853A CL2017001853A1 (es)	2008-11-19	2017-07-18	Tratamiento de trastornos cognitivos con (r)-7-cloro-n-(quinuclidin-3-il)benzo[b]tiofeno-2-carboxamida y sales farmacéuticamente aceptables de la misma (divisional de solicitud n°1707-2016).
CL2018001420A CL2018001420A1 (es)	2008-11-19	2018-05-25	Tratamiento de trastornos cognitivos con (r)-7-cloro-n-(quinuclidin-3-il)benzo[b]tiofeno-2-carboxamida y sales farmacéuticamente aceptables de la misma. (divisional solicitud 201701853)

Country Status (34)

Country	Link
US (6)	US8642638B2 (it)
EP (4)	EP2889033B1 (it)
JP (6)	JP5272080B2 (it)
KR (3)	KR20140146216A (it)
CN (3)	CN105687191A (it)
AU (1)	AU2009316557B2 (it)
BR (1)	BRPI0922057A2 (it)
CA (3)	CA2894860C (it)
CL (3)	CL2011001178A1 (it)
CO (1)	CO6400190A2 (it)
CR (1)	CR20110267A (it)
CY (3)	CY1113671T1 (it)
DK (3)	DK2889033T3 (it)
EC (1)	ECSP11011076A (it)
ES (3)	ES2396300T3 (it)
HR (3)	HRP20130007T1 (it)
HU (2)	HUE026815T2 (it)
IL (5)	IL212921A (it)
LT (1)	LT2889033T (it)
MX (1)	MX2011005270A (it)
MY (2)	MY173229A (it)
NZ (2)	NZ593467A (it)
PE (1)	PE20110711A1 (it)
PH (2)	PH12014501629B1 (it)
PL (3)	PL2889033T3 (it)
PT (3)	PT2355822E (it)
RS (1)	RS52583B (it)
RU (3)	RU2532327C2 (it)
SG (1)	SG10201504102QA (it)
SI (3)	SI2889033T1 (it)
SM (3)	SMT201800308T1 (it)
TR (1)	TR201807944T4 (it)
WO (1)	WO2010059844A1 (it)
ZA (1)	ZA201104044B (it)

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US20130137717A1 (en)	2013-05-30
EP2355822B1 (en)	2012-10-10
HK1158520A1 (en)	2012-07-20
IL256140A (en)	2018-02-28
CN105687190A (zh)	2016-06-22
EP2355822A1 (en)	2011-08-17
ES2673016T3 (es)	2018-06-19
CA2894860C (en)	2018-11-06
WO2010059844A1 (en)	2010-05-27
HUE037938T2 (hu)	2018-09-28
ZA201104044B (en)	2012-11-28
US20180271844A1 (en)	2018-09-27
EP2889033B1 (en)	2018-03-21
CY1113671T1 (el)	2016-07-27
IL256313A (en)	2018-02-28
IL242035A0 (en)	2015-11-30
RU2014122858A (ru)	2015-12-10
SMT201800308T1 (it)	2018-09-13
LT2889033T (lt)	2018-07-10
CA2894860A1 (en)	2010-05-27
HUE026815T2 (en)	2016-07-28
SI2355822T1 (sl)	2013-02-28
PH12014501629A1 (en)	2016-01-18
CR20110267A (es)	2011-10-13
RU2532327C2 (ru)	2014-11-10
JP2015083574A (ja)	2015-04-30
HRP20150711T1 (hr)	2015-08-14
KR20140146216A (ko)	2014-12-24
RU2018125456A (ru)	2020-01-13
DK2889033T3 (en)	2018-07-02
RU2011124515A (ru)	2012-12-27
US20140155430A1 (en)	2014-06-05
US8642638B2 (en)	2014-02-04
JP5869653B2 (ja)	2016-02-24
SMT201300003B (it)	2013-05-06
IL212921A (en)	2015-11-30
IL242034A (en)	2017-12-31
NZ613291A (en)	2014-11-28
HRP20130007T1 (hr)	2013-01-31
PL2355822T3 (pl)	2013-03-29
AU2009316557A1 (en)	2010-05-27
MY173229A (en)	2020-01-07
JP2020040977A (ja)	2020-03-19
CY1116460T1 (el)	2017-03-15
CO6400190A2 (es)	2012-03-15
PH12014501629B1 (en)	2016-01-18
ECSP11011076A (es)	2011-09-30
MY159826A (en)	2017-02-15
PE20110711A1 (es)	2011-10-11
EP3357495B1 (en)	2019-12-25
CA2744278A1 (en)	2010-05-27
CY1121607T1 (el)	2020-05-29
IL212921A0 (en)	2011-07-31
SI2889033T1 (en)	2018-08-31
US8569354B2 (en)	2013-10-29
CL2017001853A1 (es)	2018-05-11
DK2540297T3 (en)	2015-07-13
JP5674854B2 (ja)	2015-02-25
BRPI0922057A2 (pt)	2015-12-15
ES2396300T3 (es)	2013-02-20
NZ593467A (en)	2013-07-26
PT2355822E (pt)	2013-01-14
PT2889033T (pt)	2018-06-18
US8815933B2 (en)	2014-08-26
TR201807944T4 (tr)	2018-06-21
US20140148479A1 (en)	2014-05-29
PL2889033T3 (pl)	2018-10-31
JP2018039818A (ja)	2018-03-15
DK2355822T3 (da)	2013-01-28
CA2744278C (en)	2015-09-08
CN102281878A (zh)	2011-12-14
RU2662560C2 (ru)	2018-07-26
JP6223480B2 (ja)	2017-11-01
JP2012509347A (ja)	2012-04-19
EP2889033A1 (en)	2015-07-01
IL242034A0 (en)	2015-11-30
RS52583B (sr)	2013-04-30
SMT201500167B (it)	2015-09-07
PL2540297T3 (pl)	2015-12-31
ES2541528T3 (es)	2015-07-21
CL2018001420A1 (es)	2018-09-28
US20110288119A1 (en)	2011-11-24
EP3357495A1 (en)	2018-08-08
PH12018500023A1 (en)	2019-07-15
SI2540297T1 (sl)	2015-08-31
SG10201504102QA (en)	2015-06-29
JP5272080B2 (ja)	2013-08-28
CA3017886A1 (en)	2010-05-27
CN105687191A (zh)	2016-06-22
EP2540297B1 (en)	2015-04-08
HRP20180942T1 (hr)	2018-08-10
MX2011005270A (es)	2011-08-03
KR20110091549A (ko)	2011-08-11
US20150265583A1 (en)	2015-09-24
JP2016128442A (ja)	2016-07-14
KR20180011888A (ko)	2018-02-02
AU2009316557B2 (en)	2015-08-27
PT2540297E (pt)	2015-08-26
JP2013166771A (ja)	2013-08-29
EP2540297A1 (en)	2013-01-02

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