CL2012000799A1 - Proteína cryba que tiene una solubilidad o actividad insecticida mejorada contra al menos el gusano barrenador europeo (ostrinia nubilalis); molecula de acido nucleico que la codifica; gen quimérico, vector y celula huesped de dicho acido nucleico; método de producción; composicion insecticida; metodo para producir una planta resistente a insectos; y metodo de control de un insecto lepidóptero. - Google Patents
Proteína cryba que tiene una solubilidad o actividad insecticida mejorada contra al menos el gusano barrenador europeo (ostrinia nubilalis); molecula de acido nucleico que la codifica; gen quimérico, vector y celula huesped de dicho acido nucleico; método de producción; composicion insecticida; metodo para producir una planta resistente a insectos; y metodo de control de un insecto lepidóptero.Info
- Publication number
- CL2012000799A1 CL2012000799A1 CL2012000799A CL2012000799A CL2012000799A1 CL 2012000799 A1 CL2012000799 A1 CL 2012000799A1 CL 2012000799 A CL2012000799 A CL 2012000799A CL 2012000799 A CL2012000799 A CL 2012000799A CL 2012000799 A1 CL2012000799 A1 CL 2012000799A1
- Authority
- CL
- Chile
- Prior art keywords
- nucleic acid
- protein
- insect
- cryba
- screwworm
- Prior art date
Links
- 108090000623 proteins and genes Proteins 0.000 title abstract 7
- 102000004169 proteins and genes Human genes 0.000 title abstract 6
- 241000238631 Hexapoda Species 0.000 title abstract 3
- 150000007523 nucleic acids Chemical class 0.000 title abstract 3
- 239000000203 mixture Substances 0.000 title abstract 2
- 230000000749 insecticidal effect Effects 0.000 title 2
- 102000039446 nucleic acids Human genes 0.000 title 2
- 108020004707 nucleic acids Proteins 0.000 title 2
- 241000202814 Cochliomyia hominivorax Species 0.000 title 1
- 241001147398 Ostrinia nubilalis Species 0.000 title 1
- 150000001413 amino acids Chemical class 0.000 abstract 1
- 239000002917 insecticide Substances 0.000 abstract 1
- 230000001988 toxicity Effects 0.000 abstract 1
- 231100000419 toxicity Toxicity 0.000 abstract 1
- 230000009261 transgenic effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/32—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Bacillus (G)
- C07K14/325—Bacillus thuringiensis crystal peptides, i.e. delta-endotoxins
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01H—NEW PLANTS OR NON-TRANSGENIC PROCESSES FOR OBTAINING THEM; PLANT REPRODUCTION BY TISSUE CULTURE TECHNIQUES
- A01H5/00—Angiosperms, i.e. flowering plants, characterised by their plant parts; Angiosperms characterised otherwise than by their botanic taxonomy
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N47/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid
- A01N47/40—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having a double or triple bond to nitrogen, e.g. cyanates, cyanamides
- A01N47/42—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having a double or triple bond to nitrogen, e.g. cyanates, cyanamides containing —N=CX2 groups, e.g. isothiourea
- A01N47/44—Guanidine; Derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
- C12N15/8261—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield
- C12N15/8271—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance
- C12N15/8279—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance for biotic stress resistance, pathogen resistance, disease resistance
- C12N15/8286—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance for biotic stress resistance, pathogen resistance, disease resistance for insect resistance
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A40/00—Adaptation technologies in agriculture, forestry, livestock or agroalimentary production
- Y02A40/10—Adaptation technologies in agriculture, forestry, livestock or agroalimentary production in agriculture
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A40/00—Adaptation technologies in agriculture, forestry, livestock or agroalimentary production
- Y02A40/10—Adaptation technologies in agriculture, forestry, livestock or agroalimentary production in agriculture
- Y02A40/146—Genetically Modified [GMO] plants, e.g. transgenic plants
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Crystallography & Structural Chemistry (AREA)
- Plant Pathology (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Pest Control & Pesticides (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- Insects & Arthropods (AREA)
- Environmental Sciences (AREA)
- Botany (AREA)
- Developmental Biology & Embryology (AREA)
- Physiology (AREA)
- Agronomy & Crop Science (AREA)
- Dentistry (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
- Catching Or Destruction (AREA)
Abstract
SE DIVULGAN COMPOSICIONES Y MÉTODOS MEJORADOS PARA CONTROLAR PLAGAS. EN PARTICULAR, SE PROPORCIONAN NUEVAS PROTEÍNAS CRYL BA DISEÑADAS (ECRYL BA) QUE TIENEN TOXICIDAD MEJORADA PARA LAS PLAGAS DE INSECTOS LEPIDÓPTEROS. MEDIANTE LA SUSTITUCIÓN DE AL MENOS UN AMINOÁCIDO EN EL DOMINIO 1 DE UNA PROTEÍNA CRYL BA SE DISEÑA UNA PROTEÍNA CRYL BA DISEÑADA QUE TIENE PROPIEDADES INSECTICIDAS SUSTANCIALMENTE ALTERADAS. ASIMISMO, SE DIVULGA UN MÉTODO PARA ELABORAR LAS PROTEÍNAS CRYL BA DISEÑADAS Y MÉTODOS PARA UTILIZAR LAS SECUENCIAS DE ÁCIDOS NUCLEICOS DE ECRYL BA, POR EJEMPLO EN PLANTAS TRANSGÉNICAS PARA EXPRESAR PROTEÍNAS ECRYL B PARA CONFERIR PROTECCIÓN CONTRA EL DAÑO DE INSECTOS.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US24798609P | 2009-10-02 | 2009-10-02 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CL2012000799A1 true CL2012000799A1 (es) | 2012-10-12 |
Family
ID=43826844
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CL2012000799A CL2012000799A1 (es) | 2009-10-02 | 2012-03-30 | Proteína cryba que tiene una solubilidad o actividad insecticida mejorada contra al menos el gusano barrenador europeo (ostrinia nubilalis); molecula de acido nucleico que la codifica; gen quimérico, vector y celula huesped de dicho acido nucleico; método de producción; composicion insecticida; metodo para producir una planta resistente a insectos; y metodo de control de un insecto lepidóptero. |
Country Status (15)
| Country | Link |
|---|---|
| US (4) | US9243262B2 (es) |
| EP (1) | EP2482639B1 (es) |
| CN (2) | CN105753950B (es) |
| AU (1) | AU2010300850B2 (es) |
| BR (1) | BR112012009381A2 (es) |
| CA (1) | CA2775582A1 (es) |
| CL (1) | CL2012000799A1 (es) |
| IL (1) | IL218798A0 (es) |
| IN (1) | IN2012DN02413A (es) |
| MX (1) | MX342640B (es) |
| PH (1) | PH12012500642A1 (es) |
| RU (1) | RU2613778C2 (es) |
| UA (1) | UA110925C2 (es) |
| WO (1) | WO2011041256A2 (es) |
| ZA (1) | ZA201202266B (es) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EA029891B1 (ru) | 2008-12-16 | 2018-05-31 | Зингента Партисипейшнс Аг | Кукурузный хромосомный сайт-мишень и способ получения трансгенного растения кукурузы |
| BR112012009381A2 (pt) | 2009-10-02 | 2017-03-01 | Syngenta Participations Ag | "proteínas inseticidas" |
| US20140242048A1 (en) * | 2013-02-25 | 2014-08-28 | Beijing Dabeinong Technology Group Co., Ltd. | Methods For Controlling Pests |
| CN103146717A (zh) * | 2013-02-25 | 2013-06-12 | 北京大北农科技集团股份有限公司 | 杀虫基因及其用途 |
| BR122022020536B1 (pt) | 2013-08-08 | 2023-11-21 | Pioneer Hi-Bred International, Inc. | Molécula de ácido nucleico isolada, construto de dna, célula hospedeira bacteriana, polipeptídeo isolado, composição, método para controlar uma população, método para matar uma praga, método para produzir um polipeptídeo, método para produzir uma planta ou célula vegetal, método para proteger uma planta |
| MX388283B (es) * | 2014-10-16 | 2025-03-19 | Monsanto Technology Llc | Proteinas quimericas insecticidas novedosas toxicas o inhibidoras de plagas de lepidopteros. |
| JP6648127B2 (ja) | 2014-10-16 | 2020-02-14 | モンサント テクノロジー エルエルシー | 鱗翅類活性Cry1Da1アミノ酸配列変異体タンパク質 |
| WO2016061197A1 (en) | 2014-10-16 | 2016-04-21 | Pioneer Hi-Bred International, Inc. | Insecticidal polypeptides having improved activity spectrum and uses thereof |
| US11130964B2 (en) | 2014-11-20 | 2021-09-28 | Monsanto Technology Llc | Insect inhibitory proteins |
| RU2742467C2 (ru) | 2015-06-22 | 2021-02-08 | Агбайоми, Инк. | Пестицидные гены и способы применения |
| PL3349582T3 (pl) | 2015-08-27 | 2022-02-07 | Monsanto Technology Llc | Nowe białka hamujące owady |
| BR112018015351A2 (pt) * | 2016-01-26 | 2018-12-18 | Pioneer Hi-Bred International, Inc. | molécula de ácido nucleico isolado, construto de dna, célula hospedeira, planta transgênica, semente, polipeptídeo, composição, método para controlar uma população de praga, método para exterminar uma praga, método para produzir um polipeptídeo, método para proteger uma planta contra uma praga |
| MX2019006560A (es) * | 2016-12-12 | 2019-08-26 | Syngenta Participations Ag | Proteinas pesticidas modificadas y metodos para controlar plagas de plantas. |
| CN109517069A (zh) * | 2018-10-18 | 2019-03-26 | 先正达参股股份有限公司 | 一种用于表达Bt杀虫蛋白的高效蛋白质表达系统 |
| CN111676233A (zh) * | 2020-06-17 | 2020-09-18 | 中国农业科学院作物科学研究所 | 抗虫基因Cry1Ab-l及其编码蛋白与应用 |
| CN120647738A (zh) * | 2023-10-27 | 2025-09-16 | 安徽农业大学 | 一种杀虫蛋白及其在防治鳞翅目昆虫中的应用 |
| WO2025106342A1 (en) * | 2023-11-15 | 2025-05-22 | Syngenta Crop Protection Ag | Nucleic acid molecules for conferring insecticidal properties in plants |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| US4683202A (en) | 1985-03-28 | 1987-07-28 | Cetus Corporation | Process for amplifying nucleic acid sequences |
| US4683195A (en) | 1986-01-30 | 1987-07-28 | Cetus Corporation | Process for amplifying, detecting, and/or-cloning nucleic acid sequences |
| US4800159A (en) | 1986-02-07 | 1989-01-24 | Cetus Corporation | Process for amplifying, detecting, and/or cloning nucleic acid sequences |
| US5614395A (en) | 1988-03-08 | 1997-03-25 | Ciba-Geigy Corporation | Chemically regulatable and anti-pathogenic DNA sequences and uses thereof |
| FI891054L (fi) | 1988-03-08 | 1989-09-09 | Ciba Geigy Ag | Kemiskt reglerbara dna-sekvenser och gener samt olika anvaendningar daerav. |
| NZ230375A (en) | 1988-09-09 | 1991-07-26 | Lubrizol Genetics Inc | Synthetic gene encoding b. thuringiensis insecticidal protein |
| EP1103616A3 (en) | 1989-02-24 | 2001-06-27 | Monsanto Company | Synthetic plant genes and method for preparation |
| EP0400246A1 (en) * | 1989-05-31 | 1990-12-05 | Plant Genetic Systems, N.V. | Prevention of Bt resistance development |
| US6855873B1 (en) | 1989-05-31 | 2005-02-15 | Bayer Bioscience, N.V. | Recombinant plant expressing non-competitively binding Bt insecticidal cryatal proteins |
| US5187091A (en) * | 1990-03-20 | 1993-02-16 | Ecogen Inc. | Bacillus thuringiensis cryiiic gene encoding toxic to coleopteran insects |
| ES2187497T3 (es) | 1990-04-12 | 2003-06-16 | Syngenta Participations Ag | Promotores preferentemente en tejidos. |
| US5451513A (en) | 1990-05-01 | 1995-09-19 | The State University of New Jersey Rutgers | Method for stably transforming plastids of multicellular plants |
| GB9304200D0 (en) | 1993-03-02 | 1993-04-21 | Sandoz Ltd | Improvements in or relating to organic compounds |
| US5994629A (en) | 1991-08-28 | 1999-11-30 | Novartis Ag | Positive selection |
| UA48104C2 (uk) | 1991-10-04 | 2002-08-15 | Новартіс Аг | Фрагмент днк, який містить послідовність,що кодує інсектицидний протеїн, оптимізовану для кукурудзи,фрагмент днк, який забезпечує направлену бажану для серцевини стебла експресію зв'язаного з нею структурного гена в рослині, фрагмент днк, який забезпечує специфічну для пилку експресію зв`язаного з нею структурного гена в рослині, рекомбінантна молекула днк, спосіб одержання оптимізованої для кукурудзи кодуючої послідовності інсектицидного протеїну, спосіб захисту рослин кукурудзи щонайменше від однієї комахи-шкідника |
| US5530197A (en) * | 1992-08-19 | 1996-06-25 | Plant Genetic Systems, N.V. | Control of ostrinia |
| EP0589110A1 (en) * | 1992-08-19 | 1994-03-30 | Plant Genetic Systems N.V. | Control of ostrinia |
| US5849870A (en) | 1993-03-25 | 1998-12-15 | Novartis Finance Corporation | Pesticidal proteins and strains |
| US5877012A (en) | 1993-03-25 | 1999-03-02 | Novartis Finance Corporation | Class of proteins for the control of plant pests |
| GB9318207D0 (en) | 1993-09-02 | 1993-10-20 | Sandoz Ltd | Improvements in or relating to organic compounds |
| US5576198A (en) | 1993-12-14 | 1996-11-19 | Calgene, Inc. | Controlled expression of transgenic constructs in plant plastids |
| US5605793A (en) | 1994-02-17 | 1997-02-25 | Affymax Technologies N.V. | Methods for in vitro recombination |
| US5545818A (en) | 1994-03-11 | 1996-08-13 | Calgene Inc. | Expression of Bacillus thuringiensis cry proteins in plant plastids |
| US5545817A (en) | 1994-03-11 | 1996-08-13 | Calgene, Inc. | Enhanced expression in a plant plastid |
| US5876739A (en) | 1996-06-13 | 1999-03-02 | Novartis Ag | Insecticidal seed coating |
| US5849320A (en) | 1996-06-13 | 1998-12-15 | Novartis Corporation | Insecticidal seed coating |
| US6023013A (en) * | 1997-12-18 | 2000-02-08 | Monsanto Company | Insect-resistant transgenic plants |
| US6060594A (en) * | 1997-12-18 | 2000-05-09 | Ecogen, Inc. | Nucleic acid segments encoding modified bacillus thuringiensis coleopteran-toxic crystal proteins |
| US6121521A (en) * | 1998-04-01 | 2000-09-19 | Novartis Ag | Chimeric insecticidal protein and DNA coding therefor |
| US7253343B2 (en) | 2003-08-28 | 2007-08-07 | Athenix Corporation | AXMI-003, a delta-endotoxin gene and methods for its use |
| BR112012009381A2 (pt) | 2009-10-02 | 2017-03-01 | Syngenta Participations Ag | "proteínas inseticidas" |
-
2010
- 2010-09-27 BR BR112012009381A patent/BR112012009381A2/pt not_active Application Discontinuation
- 2010-09-27 AU AU2010300850A patent/AU2010300850B2/en not_active Revoked
- 2010-09-27 EP EP10821081.6A patent/EP2482639B1/en not_active Not-in-force
- 2010-09-27 IN IN2413DEN2012 patent/IN2012DN02413A/en unknown
- 2010-09-27 US US13/499,102 patent/US9243262B2/en active Active
- 2010-09-27 CN CN201610282033.9A patent/CN105753950B/zh active Active
- 2010-09-27 MX MX2012003658A patent/MX342640B/es active IP Right Grant
- 2010-09-27 RU RU2012117576A patent/RU2613778C2/ru not_active IP Right Cessation
- 2010-09-27 WO PCT/US2010/050369 patent/WO2011041256A2/en not_active Ceased
- 2010-09-27 CA CA2775582A patent/CA2775582A1/en not_active Abandoned
- 2010-09-27 CN CN201080044606.5A patent/CN102596988B/zh active Active
- 2010-09-27 PH PH1/2012/500642A patent/PH12012500642A1/en unknown
- 2010-09-27 UA UAA201204964A patent/UA110925C2/uk unknown
-
2012
- 2012-03-22 IL IL218798A patent/IL218798A0/en unknown
- 2012-03-28 ZA ZA2012/02266A patent/ZA201202266B/en unknown
- 2012-03-30 CL CL2012000799A patent/CL2012000799A1/es unknown
-
2015
- 2015-12-09 US US14/963,937 patent/US10196633B2/en active Active
- 2015-12-09 US US14/963,898 patent/US10167323B2/en active Active
-
2018
- 2018-12-04 US US16/208,856 patent/US10934330B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| CN102596988A (zh) | 2012-07-18 |
| AU2010300850A1 (en) | 2012-04-12 |
| US10167323B2 (en) | 2019-01-01 |
| WO2011041256A3 (en) | 2011-06-09 |
| US20160222374A1 (en) | 2016-08-04 |
| IN2012DN02413A (es) | 2015-08-21 |
| MX342640B (es) | 2016-10-07 |
| BR112012009381A2 (pt) | 2017-03-01 |
| MX2012003658A (es) | 2012-04-30 |
| EP2482639B1 (en) | 2017-08-02 |
| US9243262B2 (en) | 2016-01-26 |
| IL218798A0 (en) | 2012-06-28 |
| RU2012117576A (ru) | 2013-11-10 |
| ZA201202266B (en) | 2012-12-27 |
| CN105753950A (zh) | 2016-07-13 |
| US10934330B2 (en) | 2021-03-02 |
| CN105753950B (zh) | 2020-06-16 |
| PH12012500642A1 (en) | 2019-07-10 |
| UA110925C2 (uk) | 2016-03-10 |
| CN102596988B (zh) | 2016-07-13 |
| US20120210464A1 (en) | 2012-08-16 |
| US20190194644A1 (en) | 2019-06-27 |
| CA2775582A1 (en) | 2011-04-07 |
| EP2482639A2 (en) | 2012-08-08 |
| WO2011041256A2 (en) | 2011-04-07 |
| EP2482639A4 (en) | 2013-05-22 |
| US20160201083A1 (en) | 2016-07-14 |
| RU2613778C2 (ru) | 2017-03-21 |
| US10196633B2 (en) | 2019-02-05 |
| AU2010300850B2 (en) | 2015-02-12 |
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