CL2013003161A1 - Composicion farmaceutica en forma de microgranulos de disolucion rapida para administracion vaginal que comprende a) un farmaco vaginalmente activo, b) un excipiente polimerico, c) un alcohol de azucar, sacarido o una mezcla de los mismos; procedimiento de preparacion. - Google Patents

Composicion farmaceutica en forma de microgranulos de disolucion rapida para administracion vaginal que comprende a) un farmaco vaginalmente activo, b) un excipiente polimerico, c) un alcohol de azucar, sacarido o una mezcla de los mismos; procedimiento de preparacion.

Info

Publication number: CL2013003161A1
Authority: CL; Chile
Prior art keywords: saccharide; mixture; pharmaceutical composition; sugar alcohol; active drug
Prior art date: 2011-05-02

Application number

CL2013003161A

Other languages

English (en)

Inventor

Vijaya Swaminathan

Gopi Venkatesh

Jin Wang Lai

Original Assignee

Aptalis Pharmatech Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2011-05-02

Filing date

2013-11-04

Publication date

2014-08-01

2013-11-04 Application filed by Aptalis Pharmatech Inc filed Critical Aptalis Pharmatech Inc

2014-08-01 Publication of CL2013003161A1 publication Critical patent/CL2013003161A1/es

Links

150000001720 carbohydrates Chemical class 0.000 title 1
239000003814 drug Substances 0.000 title 1
229940079593 drug Drugs 0.000 title 1
239000000203 mixture Substances 0.000 title 1
239000008194 pharmaceutical composition Substances 0.000 title 1
239000000546 pharmaceutical excipient Substances 0.000 title 1
150000005846 sugar alcohols Chemical class 0.000 title 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/138—Aryloxyalkylamines, e.g. propranolol, tamoxifen, phenoxybenzamine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/513—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim having oxo groups directly attached to the heterocyclic ring, e.g. cytosine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/675—Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1617—Organic compounds, e.g. phospholipids, fats
- A61K9/1623—Sugars or sugar alcohols, e.g. lactose; Derivatives thereof; Homeopathic globules
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1635—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
- A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
- A—HUMAN NECESSITIES
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- A61K9/2022—Organic macromolecular compounds
- A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
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- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P15/02—Drugs for genital or sexual disorders; Contraceptives for disorders of the vagina
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
- A—HUMAN NECESSITIES
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- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P31/10—Antimycotics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
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- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

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Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Epidemiology (AREA)
General Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Immunology (AREA)
Molecular Biology (AREA)
Gynecology & Obstetrics (AREA)
Reproductive Health (AREA)
Biophysics (AREA)
Heart & Thoracic Surgery (AREA)
Oncology (AREA)
Endocrinology (AREA)
Cardiology (AREA)
Communicable Diseases (AREA)
Neurology (AREA)
Urology & Nephrology (AREA)
Neurosurgery (AREA)
Virology (AREA)
Pain & Pain Management (AREA)
Biomedical Technology (AREA)
Rheumatology (AREA)
Orthopedic Medicine & Surgery (AREA)
Psychiatry (AREA)
Transplantation (AREA)
Tropical Medicine & Parasitology (AREA)
Hematology (AREA)
Diabetes (AREA)
Anesthesiology (AREA)

CL2013003161A 2011-05-02 2013-11-04 Composicion farmaceutica en forma de microgranulos de disolucion rapida para administracion vaginal que comprende a) un farmaco vaginalmente activo, b) un excipiente polimerico, c) un alcohol de azucar, sacarido o una mezcla de los mismos; procedimiento de preparacion. CL2013003161A1 (es)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US201161481582P	2011-05-02	2011-05-02

Publications (1)

Publication Number	Publication Date
CL2013003161A1 true CL2013003161A1 (es)	2014-08-01

Family

ID=47108022

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
CL2013003161A CL2013003161A1 (es)	2011-05-02	2013-11-04	Composicion farmaceutica en forma de microgranulos de disolucion rapida para administracion vaginal que comprende a) un farmaco vaginalmente activo, b) un excipiente polimerico, c) un alcohol de azucar, sacarido o una mezcla de los mismos; procedimiento de preparacion.

Country Status (16)

Country	Link
EP (1)	EP2704694A4 (es)
JP (1)	JP6154803B2 (es)
KR (2)	KR20160112012A (es)
CN (1)	CN103596556A (es)
AP (1)	AP2013007268A0 (es)
AR (1)	AR086249A1 (es)
AU (1)	AU2012250862B2 (es)
CA (1)	CA2839790A1 (es)
CL (1)	CL2013003161A1 (es)
CO (1)	CO6940408A2 (es)
IL (1)	IL229170A0 (es)
MX (1)	MX2013012745A (es)
RU (1)	RU2013150323A (es)
SG (1)	SG194725A1 (es)
TW (1)	TW201247240A (es)
WO (1)	WO2012151237A1 (es)

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US20160030569A1 (en) *	2013-03-15	2016-02-04	Conrad	Low-glycerin formulations for hiv treatment and prevention
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MX2016008023A (es) *	2013-12-19	2017-01-13	Evofem Inc	Composiciones y metodos para inhibir la inflamacion y las enfermedades utilizando un compuesto antimicrobiano con base en acido alginico.
CN110179801B (zh) *	2014-04-11	2021-08-06	上海宣泰医药科技股份有限公司	泊沙康唑药物组合物及其制备方法和药物制剂
CA2956723C (en)	2014-08-12	2023-04-11	Nextgen Jane, Inc.	System and method for monitoring health based on collected bodily fluid
CN104434992B (zh) *	2014-12-21	2018-06-08	昆明赛诺制药股份有限公司	一种美洲大蠊提取物生物粘附性阴道片及其制备方法
US11253501B2 (en)	2015-06-01	2022-02-22	Lupin Inc.	Secnidazole formulations and use in treating bacterial vaginosis
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JP7219712B2 (ja) *	2016-10-13	2023-02-08	キャタレント・ユーケー・スウィンドン・ザイディス・リミテッド	膣送達のための凍結乾燥医薬組成物
EA202090750A1 (ru)	2017-10-06	2020-11-11	Гедеа Биотек Аб	Производные глюконовой кислоты для применения в лечении и/или предупреждении инфекций, вызываемых микроорганизмами
WO2020086705A2 (en) *	2018-10-23	2020-04-30	Eastern Virginia Medical School	Pharmaceutical compositions and methods of making on demand solid dosage formulations
CN113474008A (zh) *	2018-12-21	2021-10-01	利物浦大学	Nrti疗法
WO2020213983A1 (ko) *	2019-04-19	2020-10-22	한양대학교 산학협력단	포스파티딘산 함유 온도 감응성 조성물 및 이의 용도

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2012
- 2012-05-02 KR KR1020167025256A patent/KR20160112012A/ko not_active Ceased
- 2012-05-02 AR ARP120101551A patent/AR086249A1/es unknown
- 2012-05-02 EP EP12779335.4A patent/EP2704694A4/en not_active Withdrawn
- 2012-05-02 AU AU2012250862A patent/AU2012250862B2/en not_active Ceased
- 2012-05-02 WO PCT/US2012/036055 patent/WO2012151237A1/en not_active Ceased
- 2012-05-02 KR KR1020137031788A patent/KR20140014264A/ko not_active Ceased
- 2012-05-02 RU RU2013150323/15A patent/RU2013150323A/ru not_active Application Discontinuation
- 2012-05-02 SG SG2013080882A patent/SG194725A1/en unknown
- 2012-05-02 MX MX2013012745A patent/MX2013012745A/es unknown
- 2012-05-02 TW TW101115691A patent/TW201247240A/zh unknown
- 2012-05-02 JP JP2014509373A patent/JP6154803B2/ja not_active Expired - Fee Related
- 2012-05-02 CN CN201280026286.XA patent/CN103596556A/zh active Pending
- 2012-05-02 CA CA2839790A patent/CA2839790A1/en not_active Abandoned
- 2012-05-02 AP AP2013007268A patent/AP2013007268A0/xx unknown
2013
- 2013-10-31 IL IL229170A patent/IL229170A0/en unknown
- 2013-11-04 CL CL2013003161A patent/CL2013003161A1/es unknown
- 2013-11-29 CO CO13281162A patent/CO6940408A2/es unknown

Also Published As

Publication number	Publication date
CN103596556A (zh)	2014-02-19
JP2014513124A (ja)	2014-05-29
AR086249A1 (es)	2013-11-27
EP2704694A4 (en)	2014-11-19
CO6940408A2 (es)	2014-05-09
AU2012250862A1 (en)	2013-05-02
IL229170A0 (en)	2013-12-31
JP6154803B2 (ja)	2017-06-28
CA2839790A1 (en)	2012-11-08
KR20140014264A (ko)	2014-02-05
RU2013150323A (ru)	2015-06-10
AP2013007268A0 (en)	2013-11-30
TW201247240A (en)	2012-12-01
SG194725A1 (en)	2013-12-30
MX2013012745A (es)	2014-12-05
EP2704694A1 (en)	2014-03-12
WO2012151237A1 (en)	2012-11-08
NZ617376A (en)	2016-03-31
KR20160112012A (ko)	2016-09-27
AU2012250862B2 (en)	2015-07-09

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