BRPI0821454A2 - Formulação farmacêutica, excipiente para a preparação de formulação farmacêuticas de liberação lenta, e, processos para a produção de um excipiente de liberação lenta, e de uma forma farmacêutica. - Google Patents

Formulação farmacêutica, excipiente para a preparação de formulação farmacêuticas de liberação lenta, e, processos para a produção de um excipiente de liberação lenta, e de uma forma farmacêutica.

Info

Publication number: BRPI0821454A2
Authority: BR; Brazil
Prior art keywords: excipient; slow release; pharmaceutical; processes; preparation
Prior art date: 2007-12-28

Application number

BRPI0821454-9A

Other languages

English (en)

Inventor

Vincenzo Russo

Elisa Liberati

Nicola Cazzolla

Leonardo Marchitto

Lorella Ragni

Original Assignee

Acraf

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2007-12-28

Filing date

2008-12-23

Publication date

2015-06-16

2008-12-23 Application filed by Acraf filed Critical Acraf

2015-06-16 Publication of BRPI0821454A2 publication Critical patent/BRPI0821454A2/pt

2020-01-28 Publication of BRPI0821454B1 publication Critical patent/BRPI0821454B1/pt

2021-05-25 Publication of BRPI0821454B8 publication Critical patent/BRPI0821454B8/pt

Links

239000008194 pharmaceutical composition Substances 0.000 title 2
239000000546 pharmaceutical excipient Substances 0.000 title 2
238000004519 manufacturing process Methods 0.000 title 1
238000000034 method Methods 0.000 title 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2009—Inorganic compounds
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1611—Inorganic compounds
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/02—Nasal agents, e.g. decongestants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Medicinal Chemistry (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Epidemiology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Inorganic Chemistry (AREA)
Pulmonology (AREA)
Diabetes (AREA)
Hematology (AREA)
Otolaryngology (AREA)
Rheumatology (AREA)
Obesity (AREA)
Oncology (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Pain & Pain Management (AREA)
Endocrinology (AREA)
Communicable Diseases (AREA)
Emergency Medicine (AREA)
Hospice & Palliative Care (AREA)
Heart & Thoracic Surgery (AREA)
Cardiology (AREA)
Medicinal Preparation (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

BRPI0821454A 2007-12-28 2008-12-23 formulação farmacêutica, mistura de glicogênio, alginato e sais de metais alcalino terrosos, processos para a produção de um excipiente de liberação lenta, e de uma forma farmacêutica BRPI0821454B8 (pt)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
EP07425828		2007-12-28
PCT/EP2008/068256 WO2009083561A1 (en)	2007-12-28	2008-12-23	A slow-release formulation based on an association of glycogen and alginate

Publications (3)

Publication Number	Publication Date
BRPI0821454A2 true BRPI0821454A2 (pt)	2015-06-16
BRPI0821454B1 BRPI0821454B1 (pt)	2020-01-28
BRPI0821454B8 BRPI0821454B8 (pt)	2021-05-25

Family

ID=39522216

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
BRPI0821454A BRPI0821454B8 (pt)	2007-12-28	2008-12-23	formulação farmacêutica, mistura de glicogênio, alginato e sais de metais alcalino terrosos, processos para a produção de um excipiente de liberação lenta, e de uma forma farmacêutica

Country Status (20)

Country	Link
US (1)	US8840923B2 (pt)
EP (1)	EP2234607B1 (pt)
JP (1)	JP5416716B2 (pt)
KR (1)	KR101561571B1 (pt)
CN (1)	CN101909608B (pt)
AR (1)	AR069960A1 (pt)
AT (1)	ATE518530T1 (pt)
AU (1)	AU2008342571B2 (pt)
BR (1)	BRPI0821454B8 (pt)
CA (1)	CA2708400C (pt)
DK (1)	DK2234607T3 (pt)
EA (1)	EA018975B1 (pt)
ES (1)	ES2369868T3 (pt)
GE (1)	GEP20125636B (pt)
IL (1)	IL206124A (pt)
PL (1)	PL2234607T3 (pt)
PT (1)	PT2234607E (pt)
SI (1)	SI2234607T1 (pt)
UA (1)	UA98684C2 (pt)
WO (1)	WO2009083561A1 (pt)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
SG196810A1 (en)	2009-01-23	2014-02-13	Acraf	Controlled release pharmaceutical or foodformulation and process for its preparation
MX2012001518A (es)	2009-08-03	2012-06-08	Acraf	Formulacion alimenticia que comprende glucogeno.
BR112015027134A8 (pt) *	2013-04-26	2019-12-24	Mirexus Biotechnologies Inc	método e aditivo para mudar o comportamento reológico de uma formulação à base de água ou à base de álcool, composição e método para estabilizar uma formulação ou aumentar a fotoestabilidade de compostos orgânicos
CN106137977B (zh) *	2015-04-28	2019-12-13	浙江普利药业有限公司	海参多糖肠溶微丸及其制备方法
US11865099B2 (en)	2015-07-17	2024-01-09	Laboratori Baldacci S.P.A.	Product based on iron bis-glycinate chelate and alginic acid and/or water-soluble salts thereof, formulations thereof, and pharmaceutical uses thereof
ITUB20152290A1 (it)	2015-07-17	2017-01-17	Laboratori Baldacci Spa	Prodotto a base di ferro bisglicinato chelato e acido alginico e/o suoi sali idrosolubili, sue formulazioni ed suoi usi farmaceutici
CA3011919A1 (en) *	2016-02-08	2017-08-17	Anton Korenevski	Moisturizing personal care compositions comprising monodisperse phytoglycogen nanoparticles and a further polysaccharide

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3640741A (en) *	1970-02-24	1972-02-08	Hollister Inc	Composition containing gel
DE2062715C3 (de) *	1970-12-19	1974-03-21	Efeka Friedrich & Kaufmann Arzneimittelfabrik, 3000 Hannover	Verfahren zur Herstellung von oral applizierbaren Arzneimittelzubereitungen mit protrahierter Wirkstoffabgabe und Arzneimittelzubereitung
DE3583799D1 (de) *	1985-01-11	1991-09-19	Abbott Lab Ltd	Feste zubereitung mit langsamer freisetzung.
JPS62178505A (ja)	1986-02-03	1987-08-05	Maruzen Kasei Kk	化粧料
JPS63290809A (ja)	1987-05-25	1988-11-28	Noebia:Kk	口唇用化粧料
CA2041774C (en) *	1990-11-27	1994-04-19	Mircea A. Mateescu	Use of cross-linked amylose as a matrix for the slow release of biologically active compounds
IT1255488B (it)	1992-08-04	1995-11-06	Angelini Francesco Ist Ricerca	Polisaccaridi del glicogeno
US5705190A (en) *	1995-12-19	1998-01-06	Abbott Laboratories	Controlled release formulation for poorly soluble basic drugs
US5807575A (en)	1997-02-14	1998-09-15	Rougier Inc.	Manufacture of cross-linked amylose useful as a excipient for control release of active compounds
IT1298758B1 (it)	1998-03-19	2000-02-02	Angelini Ricerche Spa	Soluzione umettante e lubrificante per uso oftalmico
US6607748B1 (en) *	2000-06-29	2003-08-19	Vincent Lenaerts	Cross-linked high amylose starch for use in controlled-release pharmaceutical formulations and processes for its manufacture
AU2001227030A1 (en) *	2000-11-22	2002-06-03	Lupin Laboratories Limited	Pharmaceutical composition for controlled release of an active ingredient
CA2638788A1 (en) *	2003-04-25	2004-11-11	Kos Life Sciences, Inc.	Formation of strong superporous hydrogels
US20060067917A1 (en) *	2004-09-20	2006-03-30	Athanassios Sambanis	Insulin delivery system
US7687608B2 (en) *	2005-10-19	2010-03-30	Smartcells, Inc.	Methods for reducing the mitogenicity of lectin compositions

2008
- 2008-12-23 PT PT08867925T patent/PT2234607E/pt unknown
- 2008-12-23 AT AT08867925T patent/ATE518530T1/de active
- 2008-12-23 US US12/745,816 patent/US8840923B2/en not_active Expired - Fee Related
- 2008-12-23 UA UAA201007866A patent/UA98684C2/uk unknown
- 2008-12-23 ES ES08867925T patent/ES2369868T3/es active Active
- 2008-12-23 CN CN2008801227782A patent/CN101909608B/zh not_active Expired - Fee Related
- 2008-12-23 EP EP08867925A patent/EP2234607B1/en active Active
- 2008-12-23 SI SI200830407T patent/SI2234607T1/sl unknown
- 2008-12-23 JP JP2010540124A patent/JP5416716B2/ja not_active Expired - Fee Related
- 2008-12-23 WO PCT/EP2008/068256 patent/WO2009083561A1/en not_active Ceased
- 2008-12-23 PL PL08867925T patent/PL2234607T3/pl unknown
- 2008-12-23 GE GEAP200811898A patent/GEP20125636B/en unknown
- 2008-12-23 KR KR1020107015913A patent/KR101561571B1/ko not_active Expired - Fee Related
- 2008-12-23 AR ARP080105697A patent/AR069960A1/es not_active Application Discontinuation
- 2008-12-23 EA EA201070806A patent/EA018975B1/ru not_active IP Right Cessation
- 2008-12-23 DK DK08867925.3T patent/DK2234607T3/da active
- 2008-12-23 BR BRPI0821454A patent/BRPI0821454B8/pt not_active IP Right Cessation
- 2008-12-23 AU AU2008342571A patent/AU2008342571B2/en not_active Ceased
- 2008-12-23 CA CA2708400A patent/CA2708400C/en not_active Expired - Fee Related
2010
- 2010-06-01 IL IL206124A patent/IL206124A/en active IP Right Grant

Also Published As

Publication number	Publication date
IL206124A (en)	2013-01-31
ES2369868T3 (es)	2011-12-07
KR101561571B1 (ko)	2015-10-19
DK2234607T3 (da)	2011-11-21
AR069960A1 (es)	2010-03-03
UA98684C2 (uk)	2012-06-11
JP2011519820A (ja)	2011-07-14
EA018975B1 (ru)	2013-12-30
IL206124A0 (en)	2010-11-30
BRPI0821454B1 (pt)	2020-01-28
EA201070806A1 (ru)	2010-12-30
PL2234607T3 (pl)	2011-12-30
US8840923B2 (en)	2014-09-23
CA2708400A1 (en)	2009-07-09
CA2708400C (en)	2016-02-02
CN101909608B (zh)	2013-01-23
JP5416716B2 (ja)	2014-02-12
GEP20125636B (en)	2012-09-10
CN101909608A (zh)	2010-12-08
PT2234607E (pt)	2011-09-30
KR20100099728A (ko)	2010-09-13
AU2008342571B2 (en)	2014-03-13
ATE518530T1 (de)	2011-08-15
SI2234607T1 (sl)	2011-11-30
HK1145284A1 (en)	2011-04-15
US20100255083A1 (en)	2010-10-07
BRPI0821454B8 (pt)	2021-05-25
AU2008342571A1 (en)	2009-07-09
WO2009083561A1 (en)	2009-07-09
EP2234607A1 (en)	2010-10-06
EP2234607B1 (en)	2011-08-03

Legal Events

Date	Code	Title	Description
2017-10-10	B07D	Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
2018-04-17	B06F	Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
2019-04-16	B07E	Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]	Free format text: NOTIFICACAO DE ANUENCIA RELACIONADA COM O ART 229 DA LPI
2019-07-09	B07A	Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
2019-12-03	B09A	Decision: intention to grant [chapter 9.1 patent gazette]
2019-12-17	B09X	Republication of the decision to grant [chapter 9.1.3 patent gazette]
2020-01-28	B16A	Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]	Free format text: PRAZO DE VALIDADE: 10 (DEZ) ANOS CONTADOS A PARTIR DE 28/01/2020, OBSERVADAS AS CONDICOES LEGAIS.
2021-05-25	B16C	Correction of notification of the grant [chapter 16.3 patent gazette]	Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 23/12/2008 OBSERVADAS AS CONDICOES LEGAIS. PATENTE CONCEDIDA CONFORME ADI 5.529/DF
2021-10-19	B21F	Lapse acc. art. 78, item iv - on non-payment of the annual fees in time	Free format text: REFERENTE A 13A ANUIDADE.
2022-02-08	B24J	Lapse because of non-payment of annual fees (definitively: art 78 iv lpi, resolution 113/2013 art. 12)	Free format text: EM VIRTUDE DA EXTINCAO PUBLICADA NA RPI 2650 DE 19-10-2021 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDA A EXTINCAO DA PATENTE E SEUS CERTIFICADOS, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.

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BRPI0914918A2 (pt)	2015-10-20	forma de dosagem farmacêutica, e, método para preparar uma forma de dosagem sólida.
BRPI0915084A2 (pt)	2015-10-27	composto, processo para a preparação de um composto, composição farmacêutica, uso de um composto, métodos para a profilaxia ou tratamento de um estado de doença ou uma condição e de câncer
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BRPI0818680A2 (pt)	2017-05-02	composição farmacêutica, preparação farmacêutica, e método para preparar um forma de dosagem oral farmacêutica
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BR112014010206A2 (pt)	2017-05-16	composto, composição farmacêutica, uso de composto, e, método para a profilaxia ou tratamento de um estado ou condição de doença
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