CL2014000103A1 - Metodo para determinar el pronostico de una enfermedad o la prognosis de un paciente diagnosticado con mieloma multiple. - Google Patents

Metodo para determinar el pronostico de una enfermedad o la prognosis de un paciente diagnosticado con mieloma multiple.

Info

Publication number
CL2014000103A1
CL2014000103A1 CL2014000103A CL2014000103A CL2014000103A1 CL 2014000103 A1 CL2014000103 A1 CL 2014000103A1 CL 2014000103 A CL2014000103 A CL 2014000103A CL 2014000103 A CL2014000103 A CL 2014000103A CL 2014000103 A1 CL2014000103 A1 CL 2014000103A1
Authority
CL
Chile
Prior art keywords
prognosis
disease
multiple myeloma
patient diagnosed
diagnosed
Prior art date
Application number
CL2014000103A
Other languages
English (en)
Inventor
Rowan Kuiper
Pieter Sonneveld
Original Assignee
Univ Erasmus Medical Ct
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Erasmus Medical Ct filed Critical Univ Erasmus Medical Ct
Publication of CL2014000103A1 publication Critical patent/CL2014000103A1/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813Hybridisation assays
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813Hybridisation assays
    • C12Q1/6834Enzymatic or biochemical coupling of nucleic acids to a solid phase
    • C12Q1/6837Enzymatic or biochemical coupling of nucleic acids to a solid phase using probe arrays or probe chips
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/112Disease subtyping, staging or classification
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/118Prognosis of disease development
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/158Expression markers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Analytical Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Pathology (AREA)
  • Hospice & Palliative Care (AREA)
  • Oncology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
CL2014000103A 2011-07-14 2014-01-14 Metodo para determinar el pronostico de una enfermedad o la prognosis de un paciente diagnosticado con mieloma multiple. CL2014000103A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP11173971A EP2546357A1 (en) 2011-07-14 2011-07-14 A new classifier for the molecular classification of multiple myeloma.

Publications (1)

Publication Number Publication Date
CL2014000103A1 true CL2014000103A1 (es) 2014-07-04

Family

ID=46506441

Family Applications (1)

Application Number Title Priority Date Filing Date
CL2014000103A CL2014000103A1 (es) 2011-07-14 2014-01-14 Metodo para determinar el pronostico de una enfermedad o la prognosis de un paciente diagnosticado con mieloma multiple.

Country Status (18)

Country Link
US (3) US9976185B2 (es)
EP (2) EP2546357A1 (es)
JP (1) JP6026529B2 (es)
KR (1) KR101933742B1 (es)
AU (1) AU2012282437B2 (es)
BR (1) BR112014000648B1 (es)
CA (1) CA2841536C (es)
CL (1) CL2014000103A1 (es)
DK (1) DK2732048T3 (es)
EA (1) EA032730B1 (es)
ES (1) ES2633165T3 (es)
IL (1) IL230164A (es)
MX (1) MX346314B (es)
NZ (1) NZ619896A (es)
PL (1) PL2732048T3 (es)
PT (1) PT2732048T (es)
WO (1) WO2013007795A1 (es)
ZA (1) ZA201400159B (es)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2546357A1 (en) 2011-07-14 2013-01-16 Erasmus University Medical Center Rotterdam A new classifier for the molecular classification of multiple myeloma.
EP3414574A2 (en) * 2016-02-12 2018-12-19 Skylinedx B.V. Predicting response to immunomodulatory drugs (imids) in multiple myeloma patients
WO2018186740A1 (en) 2017-04-04 2018-10-11 Skylinedx B.V Method for identifying gene expression signatures
US10973820B2 (en) 2017-12-13 2021-04-13 Facio Intellectual Property B.V. Compounds for treatment of diseases related to DUX4 expression
US12235271B2 (en) 2018-04-28 2025-02-25 Beijing Normal University Molecular typing of multiple myeloma and application
CN110218789B (zh) * 2019-04-22 2022-10-04 曾文炳 一种用于预测多发性骨髓瘤患者总体生存率的基因探针组合物及试剂盒
TW202112368A (zh) 2019-06-13 2021-04-01 荷蘭商法西歐知識產權股份有限公司 用於治療有關dux4表現之疾病的抑制劑組合
JP2023503988A (ja) 2019-11-29 2023-02-01 ファシオ インテレクチュアル プロパティ ビー.ヴイ. Dux4発現に関連する疾患を処置するための新たな化合物
EP4065110A1 (en) 2019-11-29 2022-10-05 Facio Intellectual Property B.V. Novel compounds for treatment of diseases related to dux4 expression
CN120945052A (zh) * 2025-08-05 2025-11-14 中国人民解放军海军特色医学中心 评估多发性骨髓瘤预后及prmm风险的基因组合及其评估方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20070015146A1 (en) * 2001-05-22 2007-01-18 Gene Logic, Inc. Molecular nephrotoxicology modeling
WO2003053215A2 (en) * 2001-11-07 2003-07-03 The Board Of Trustees Of The University Of Arkansas Diagnosis prognosis and identification of potential therapeutic targets of multiple myeloma based on gene expression profiling
US20080274911A1 (en) * 2006-11-07 2008-11-06 Burington Bart E Gene expression profiling based identification of genomic signature of high-risk multiple myeloma and uses thereof
DK2087139T3 (en) * 2006-11-07 2017-02-13 Univ Arkansas Gene expression profiling-based identification of high-risk multiple myeloma genomic signatures
EP1964930A1 (en) * 2007-02-28 2008-09-03 Institut National De La Sante Et De La Recherche Medicale (Inserm) Molecular classifier for prognosis in multiple myeloma
US20110301055A1 (en) * 2008-12-05 2011-12-08 Nicholas James Dickens Methods for determining a prognosis in multiple myeloma
WO2010151731A1 (en) * 2009-06-26 2010-12-29 University Of Utah Research Foundation Materials and methods for the identification of drug-resistant cancers and treatment of same
EP2546357A1 (en) 2011-07-14 2013-01-16 Erasmus University Medical Center Rotterdam A new classifier for the molecular classification of multiple myeloma.

Also Published As

Publication number Publication date
AU2012282437B2 (en) 2016-04-21
MX2014000440A (es) 2014-07-09
MX346314B (es) 2017-03-15
US10815532B2 (en) 2020-10-27
DK2732048T3 (en) 2017-08-07
ZA201400159B (en) 2017-09-27
US20180237866A1 (en) 2018-08-23
KR20140044364A (ko) 2014-04-14
KR101933742B1 (ko) 2018-12-28
PL2732048T3 (pl) 2017-10-31
US9976185B2 (en) 2018-05-22
ES2633165T3 (es) 2017-09-19
WO2013007795A1 (en) 2013-01-17
NZ619896A (en) 2016-04-29
JP6026529B2 (ja) 2016-11-16
CA2841536A1 (en) 2013-01-17
EA032730B1 (ru) 2019-07-31
BR112014000648A2 (pt) 2017-02-14
US20210010091A1 (en) 2021-01-14
EP2732048B1 (en) 2017-05-10
EA201400131A1 (ru) 2014-04-30
CA2841536C (en) 2020-09-22
EP2546357A1 (en) 2013-01-16
JP2014520540A (ja) 2014-08-25
PT2732048T (pt) 2017-07-18
US20140221313A1 (en) 2014-08-07
EP2732048A1 (en) 2014-05-21
IL230164A (en) 2017-12-31
BR112014000648B1 (pt) 2020-04-07
AU2012282437A1 (en) 2014-01-23

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