PT2732048T - Novo classificador para a classificação molecular de mieloma múltiplo - Google Patents
Novo classificador para a classificação molecular de mieloma múltiploInfo
- Publication number
- PT2732048T PT2732048T PT127337657T PT12733765T PT2732048T PT 2732048 T PT2732048 T PT 2732048T PT 127337657 T PT127337657 T PT 127337657T PT 12733765 T PT12733765 T PT 12733765T PT 2732048 T PT2732048 T PT 2732048T
- Authority
- PT
- Portugal
- Prior art keywords
- multiple myeloma
- molecular classification
- new classifier
- classifier
- classification
- Prior art date
Links
- 208000034578 Multiple myelomas Diseases 0.000 title 1
- 206010035226 Plasma cell myeloma Diseases 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6834—Enzymatic or biochemical coupling of nucleic acids to a solid phase
- C12Q1/6837—Enzymatic or biochemical coupling of nucleic acids to a solid phase using probe arrays or probe chips
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
- C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/112—Disease subtyping, staging or classification
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/118—Prognosis of disease development
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Analytical Chemistry (AREA)
- Genetics & Genomics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Microbiology (AREA)
- Pathology (AREA)
- Hospice & Palliative Care (AREA)
- Oncology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP11173971A EP2546357A1 (en) | 2011-07-14 | 2011-07-14 | A new classifier for the molecular classification of multiple myeloma. |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT2732048T true PT2732048T (pt) | 2017-07-18 |
Family
ID=46506441
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT127337657T PT2732048T (pt) | 2011-07-14 | 2012-07-12 | Novo classificador para a classificação molecular de mieloma múltiplo |
Country Status (18)
| Country | Link |
|---|---|
| US (3) | US9976185B2 (pt) |
| EP (2) | EP2546357A1 (pt) |
| JP (1) | JP6026529B2 (pt) |
| KR (1) | KR101933742B1 (pt) |
| AU (1) | AU2012282437B2 (pt) |
| BR (1) | BR112014000648B1 (pt) |
| CA (1) | CA2841536C (pt) |
| CL (1) | CL2014000103A1 (pt) |
| DK (1) | DK2732048T3 (pt) |
| EA (1) | EA032730B1 (pt) |
| ES (1) | ES2633165T3 (pt) |
| IL (1) | IL230164A (pt) |
| MX (1) | MX346314B (pt) |
| NZ (1) | NZ619896A (pt) |
| PL (1) | PL2732048T3 (pt) |
| PT (1) | PT2732048T (pt) |
| WO (1) | WO2013007795A1 (pt) |
| ZA (1) | ZA201400159B (pt) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2546357A1 (en) | 2011-07-14 | 2013-01-16 | Erasmus University Medical Center Rotterdam | A new classifier for the molecular classification of multiple myeloma. |
| EP3414574A2 (en) * | 2016-02-12 | 2018-12-19 | Skylinedx B.V. | Predicting response to immunomodulatory drugs (imids) in multiple myeloma patients |
| WO2018186740A1 (en) | 2017-04-04 | 2018-10-11 | Skylinedx B.V | Method for identifying gene expression signatures |
| US10973820B2 (en) | 2017-12-13 | 2021-04-13 | Facio Intellectual Property B.V. | Compounds for treatment of diseases related to DUX4 expression |
| US12235271B2 (en) | 2018-04-28 | 2025-02-25 | Beijing Normal University | Molecular typing of multiple myeloma and application |
| CN110218789B (zh) * | 2019-04-22 | 2022-10-04 | 曾文炳 | 一种用于预测多发性骨髓瘤患者总体生存率的基因探针组合物及试剂盒 |
| TW202112368A (zh) | 2019-06-13 | 2021-04-01 | 荷蘭商法西歐知識產權股份有限公司 | 用於治療有關dux4表現之疾病的抑制劑組合 |
| CA3159239A1 (en) | 2019-11-29 | 2021-06-03 | Pui Leng Loke | Novel compounds for treatment of diseases related to dux4 expression |
| WO2021105474A1 (en) | 2019-11-29 | 2021-06-03 | Facio Intellectual Property B.V. | New compounds for treatment of diseases related to dux4 expression |
| CN120945052A (zh) * | 2025-08-05 | 2025-11-14 | 中国人民解放军海军特色医学中心 | 评估多发性骨髓瘤预后及prmm风险的基因组合及其评估方法 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20070015146A1 (en) * | 2001-05-22 | 2007-01-18 | Gene Logic, Inc. | Molecular nephrotoxicology modeling |
| JP2005512557A (ja) * | 2001-11-07 | 2005-05-12 | ザ ボード オブ トラスティーズ オブ ザ ユニヴァーシティー オブ アーカンソー | 遺伝子発現プロファイリングに基づく多発性骨髄腫の診断、予後、および治療標的候補の同定 |
| US20080274911A1 (en) * | 2006-11-07 | 2008-11-06 | Burington Bart E | Gene expression profiling based identification of genomic signature of high-risk multiple myeloma and uses thereof |
| DK2087139T3 (en) * | 2006-11-07 | 2017-02-13 | Univ Arkansas | Gene expression profiling-based identification of high-risk multiple myeloma genomic signatures |
| EP1964930A1 (en) * | 2007-02-28 | 2008-09-03 | Institut National De La Sante Et De La Recherche Medicale (Inserm) | Molecular classifier for prognosis in multiple myeloma |
| US20110301055A1 (en) * | 2008-12-05 | 2011-12-08 | Nicholas James Dickens | Methods for determining a prognosis in multiple myeloma |
| WO2010151731A1 (en) * | 2009-06-26 | 2010-12-29 | University Of Utah Research Foundation | Materials and methods for the identification of drug-resistant cancers and treatment of same |
| EP2546357A1 (en) | 2011-07-14 | 2013-01-16 | Erasmus University Medical Center Rotterdam | A new classifier for the molecular classification of multiple myeloma. |
-
2011
- 2011-07-14 EP EP11173971A patent/EP2546357A1/en not_active Withdrawn
-
2012
- 2012-07-12 PT PT127337657T patent/PT2732048T/pt unknown
- 2012-07-12 KR KR1020147000834A patent/KR101933742B1/ko active Active
- 2012-07-12 CA CA2841536A patent/CA2841536C/en active Active
- 2012-07-12 DK DK12733765.7T patent/DK2732048T3/en active
- 2012-07-12 WO PCT/EP2012/063722 patent/WO2013007795A1/en not_active Ceased
- 2012-07-12 JP JP2014519565A patent/JP6026529B2/ja active Active
- 2012-07-12 ES ES12733765.7T patent/ES2633165T3/es active Active
- 2012-07-12 NZ NZ619896A patent/NZ619896A/en unknown
- 2012-07-12 EA EA201400131A patent/EA032730B1/ru not_active IP Right Cessation
- 2012-07-12 MX MX2014000440A patent/MX346314B/es active IP Right Grant
- 2012-07-12 US US14/232,176 patent/US9976185B2/en active Active
- 2012-07-12 EP EP12733765.7A patent/EP2732048B1/en active Active
- 2012-07-12 PL PL12733765T patent/PL2732048T3/pl unknown
- 2012-07-12 AU AU2012282437A patent/AU2012282437B2/en active Active
- 2012-07-12 BR BR112014000648A patent/BR112014000648B1/pt not_active IP Right Cessation
-
2013
- 2013-12-25 IL IL230164A patent/IL230164A/en active IP Right Grant
-
2014
- 2014-01-08 ZA ZA2014/00159A patent/ZA201400159B/en unknown
- 2014-01-14 CL CL2014000103A patent/CL2014000103A1/es unknown
-
2018
- 2018-04-23 US US15/959,703 patent/US10815532B2/en active Active
-
2020
- 2020-09-23 US US17/029,564 patent/US20210010091A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| US9976185B2 (en) | 2018-05-22 |
| EP2732048B1 (en) | 2017-05-10 |
| US10815532B2 (en) | 2020-10-27 |
| AU2012282437A1 (en) | 2014-01-23 |
| NZ619896A (en) | 2016-04-29 |
| MX2014000440A (es) | 2014-07-09 |
| DK2732048T3 (en) | 2017-08-07 |
| BR112014000648B1 (pt) | 2020-04-07 |
| CL2014000103A1 (es) | 2014-07-04 |
| US20180237866A1 (en) | 2018-08-23 |
| IL230164A (en) | 2017-12-31 |
| EP2546357A1 (en) | 2013-01-16 |
| ES2633165T3 (es) | 2017-09-19 |
| JP2014520540A (ja) | 2014-08-25 |
| US20210010091A1 (en) | 2021-01-14 |
| MX346314B (es) | 2017-03-15 |
| WO2013007795A1 (en) | 2013-01-17 |
| CA2841536A1 (en) | 2013-01-17 |
| ZA201400159B (en) | 2017-09-27 |
| BR112014000648A2 (pt) | 2017-02-14 |
| EP2732048A1 (en) | 2014-05-21 |
| JP6026529B2 (ja) | 2016-11-16 |
| AU2012282437B2 (en) | 2016-04-21 |
| EA032730B1 (ru) | 2019-07-31 |
| KR101933742B1 (ko) | 2018-12-28 |
| US20140221313A1 (en) | 2014-08-07 |
| KR20140044364A (ko) | 2014-04-14 |
| PL2732048T3 (pl) | 2017-10-31 |
| EA201400131A1 (ru) | 2014-04-30 |
| CA2841536C (en) | 2020-09-22 |
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