Classifications

• • A—HUMAN NECESSITIES
  • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
  • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
  • A61K31/00—Medicinal preparations containing organic active ingredients
  • A61K31/33—Heterocyclic compounds
  • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
  • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
• • A—HUMAN NECESSITIES
  • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
  • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
  • A61K31/00—Medicinal preparations containing organic active ingredients
  • A61K31/12—Ketones
  • A61K31/122—Ketones having the oxygen directly attached to a ring, e.g. quinones, vitamin K1, anthralin
• • A—HUMAN NECESSITIES
  • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
  • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
  • A61K31/00—Medicinal preparations containing organic active ingredients
  • A61K31/33—Heterocyclic compounds
  • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
  • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
  • A61K31/4965—Non-condensed pyrazines
• • A—HUMAN NECESSITIES
  • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
  • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
  • A61K9/00—Medicinal preparations characterised by special physical form
  • A61K9/0012—Galenical forms characterised by the site of application
  • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
• • A—HUMAN NECESSITIES
  • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
  • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
  • A61P11/00—Drugs for disorders of the respiratory system
• • A—HUMAN NECESSITIES
  • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
  • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
  • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
• • A—HUMAN NECESSITIES
  • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
  • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
  • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
  • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
• • A—HUMAN NECESSITIES
  • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
  • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
  • A61P9/00—Drugs for disorders of the cardiovascular system
  • A61P9/06—Antiarrhythmics
• • A—HUMAN NECESSITIES
  • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
  • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
  • A61P9/00—Drugs for disorders of the cardiovascular system
  • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
• • C—CHEMISTRY; METALLURGY
  • C07—ORGANIC CHEMISTRY
  • C07D—HETEROCYCLIC COMPOUNDS
  • C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
  • C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
  • C07D241/04—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
• • C—CHEMISTRY; METALLURGY
  • C07—ORGANIC CHEMISTRY
  • C07D—HETEROCYCLIC COMPOUNDS
  • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
  • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
  • C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
  • C07D295/125—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
  • C07D295/13—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain

Landscapes

• Health & Medical Sciences (AREA)
• Chemical & Material Sciences (AREA)
• Organic Chemistry (AREA)
• Life Sciences & Earth Sciences (AREA)
• General Health & Medical Sciences (AREA)
• Veterinary Medicine (AREA)
• Public Health (AREA)
• Animal Behavior & Ethology (AREA)
• Pharmacology & Pharmacy (AREA)
• Medicinal Chemistry (AREA)
• Epidemiology (AREA)
• Bioinformatics & Cheminformatics (AREA)
• Engineering & Computer Science (AREA)
• Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
• Chemical Kinetics & Catalysis (AREA)
• General Chemical & Material Sciences (AREA)
• Heart & Thoracic Surgery (AREA)
• Cardiology (AREA)
• Diabetes (AREA)
• Hematology (AREA)
• Physiology (AREA)
• Nutrition Science (AREA)
• Urology & Nephrology (AREA)
• Pulmonology (AREA)
• Vascular Medicine (AREA)
• Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
• Investigating Or Analysing Biological Materials (AREA)
• Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
• Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
• Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Applications Claiming Priority (4)

Publications (1)

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Family Applications (1)

Country Status (34)

Families Citing this family (14)

Family Cites Families (23)

• 2012
  • 2012-11-29 WO PCT/US2012/066938 patent/WO2013082210A1/en not_active Ceased
  • 2012-11-29 ME MEP-2016-95A patent/ME02424B/me unknown
  • 2012-11-29 SI SI201230558A patent/SI2785700T1/sl unknown
  • 2012-11-29 US US13/688,442 patent/US9522892B2/en active Active
  • 2012-11-29 DK DK12806229.6T patent/DK2785700T3/en active
  • 2012-11-29 PT PT128062296T patent/PT2785700E/pt unknown
  • 2012-11-29 MX MX2014006349A patent/MX349514B/es active IP Right Grant
  • 2012-11-29 EA EA201490823A patent/EA027603B1/ru unknown
  • 2012-11-29 CA CA2856540A patent/CA2856540C/en active Active
  • 2012-11-29 UA UAA201404997A patent/UA116336C2/uk unknown
  • 2012-11-29 JP JP2014544857A patent/JP6134731B2/ja active Active
  • 2012-11-29 EP EP12806229.6A patent/EP2785700B1/en active Active
  • 2012-11-29 KR KR1020147016304A patent/KR101892330B1/ko active Active
  • 2012-11-29 PE PE2014000763A patent/PE20141295A1/es active IP Right Grant
  • 2012-11-29 HR HRP20160513TT patent/HRP20160513T1/hr unknown
  • 2012-11-29 BR BR112014012892-8A patent/BR112014012892B1/pt active IP Right Grant
  • 2012-11-29 HU HUE12806229A patent/HUE027452T2/en unknown
  • 2012-11-29 PL PL12806229.6T patent/PL2785700T3/pl unknown
  • 2012-11-29 RS RS20160318A patent/RS54738B1/sr unknown
  • 2012-11-29 ES ES12806229.6T patent/ES2569674T3/es active Active
  • 2012-11-29 SG SG11201402713WA patent/SG11201402713WA/en unknown
  • 2012-11-29 AU AU2012345975A patent/AU2012345975B2/en active Active
  • 2012-11-29 AR ARP120104474A patent/AR089020A1/es active IP Right Grant
  • 2012-11-29 CN CN201280060950.2A patent/CN104080772B/zh active Active
  • 2012-11-29 AP AP2014007662A patent/AP2014007662A0/xx unknown
• 2014
  • 2014-05-26 PH PH12014501176A patent/PH12014501176B1/en unknown
  • 2014-05-26 IL IL232788A patent/IL232788B/en active IP Right Grant
  • 2014-05-27 CL CL2014001399A patent/CL2014001399A1/es unknown
  • 2014-06-26 CO CO14137450A patent/CO6990738A2/es unknown
  • 2014-06-26 CR CR20140310A patent/CR20140310A/es unknown
  • 2014-06-26 EC ECIEPI20146696A patent/ECSP14006696A/es unknown
  • 2014-06-27 ZA ZA2014/04793A patent/ZA201404793B/en unknown
• 2016
  • 2016-04-25 CY CY20161100338T patent/CY1117414T1/el unknown
  • 2016-06-08 SM SM201600161T patent/SMT201600161B/it unknown
  • 2016-11-10 US US15/348,348 patent/US9877961B2/en active Active
• 2017
  • 2017-10-06 US US15/726,497 patent/US20180207152A1/en not_active Abandoned
• 2020
  • 2020-12-10 US US17/117,559 patent/US20210169874A1/en not_active Abandoned
• 2023
  • 2023-12-15 US US18/541,391 patent/US20240366592A1/en active Pending

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