CL2014002465A1 - Procedimiento para producir microcapsulas entericas de alginato de calcio que contienen diclofenaco o una de sus sales; composición farmacéutica oral que las comprende; combinacion farmaceutica. - Google Patents
Procedimiento para producir microcapsulas entericas de alginato de calcio que contienen diclofenaco o una de sus sales; composición farmacéutica oral que las comprende; combinacion farmaceutica.Info
- Publication number
- CL2014002465A1 CL2014002465A1 CL2014002465A CL2014002465A CL2014002465A1 CL 2014002465 A1 CL2014002465 A1 CL 2014002465A1 CL 2014002465 A CL2014002465 A CL 2014002465A CL 2014002465 A CL2014002465 A CL 2014002465A CL 2014002465 A1 CL2014002465 A1 CL 2014002465A1
- Authority
- CL
- Chile
- Prior art keywords
- salts
- procedure
- calcium alginate
- pharmaceutical composition
- containing diclofenac
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/196—Carboxylic acids, e.g. valproic acid having an amino group the amino group being directly attached to a ring, e.g. anthranilic acid, mefenamic acid, diclofenac, chlorambucil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
- A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
- A61K9/2081—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets with microcapsules or coated microparticles according to A61K9/50
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5084—Mixtures of one or more drugs in different galenical forms, at least one of which being granules, microcapsules or (coated) microparticles according to A61K9/16 or A61K9/50, e.g. for obtaining a specific release pattern or for combining different drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5089—Processes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Dispersion Chemistry (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
- Zoology (AREA)
- Inorganic Chemistry (AREA)
- Pain & Pain Management (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Rheumatology (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CL2016003348A CL2016003348A1 (es) | 2012-03-20 | 2016-12-27 | Procedimiento para preparar microcápsulas entéricas de alginato de calcio que contienen diclofenaco o una de sus sales mediante gelificación iónica, opcionalmente recubiertas con un polímero de metacrilato. (divisional sol. 2465-2014) |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/EP2012/054904 WO2013139377A1 (en) | 2012-03-20 | 2012-03-20 | Method for producing enteric alginate microcapsules via ionic gelation containing diclofenac or one of the salts thereof and multiparticled pharmaceutical composition containing them |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CL2014002465A1 true CL2014002465A1 (es) | 2015-05-08 |
Family
ID=45855800
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CL2014002465A CL2014002465A1 (es) | 2012-03-20 | 2014-09-17 | Procedimiento para producir microcapsulas entericas de alginato de calcio que contienen diclofenaco o una de sus sales; composición farmacéutica oral que las comprende; combinacion farmaceutica. |
| CL2016003348A CL2016003348A1 (es) | 2012-03-20 | 2016-12-27 | Procedimiento para preparar microcápsulas entéricas de alginato de calcio que contienen diclofenaco o una de sus sales mediante gelificación iónica, opcionalmente recubiertas con un polímero de metacrilato. (divisional sol. 2465-2014) |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CL2016003348A CL2016003348A1 (es) | 2012-03-20 | 2016-12-27 | Procedimiento para preparar microcápsulas entéricas de alginato de calcio que contienen diclofenaco o una de sus sales mediante gelificación iónica, opcionalmente recubiertas con un polímero de metacrilato. (divisional sol. 2465-2014) |
Country Status (15)
| Country | Link |
|---|---|
| US (2) | US9668978B2 (es) |
| EP (1) | EP2827843B1 (es) |
| CN (1) | CN104244927B (es) |
| AR (1) | AR090187A1 (es) |
| BR (1) | BR112014023278B1 (es) |
| CA (1) | CA2899664C (es) |
| CL (2) | CL2014002465A1 (es) |
| ES (1) | ES2584403T3 (es) |
| MX (1) | MX354454B (es) |
| PH (1) | PH12014501981B1 (es) |
| PL (1) | PL2827843T3 (es) |
| SG (1) | SG11201505320TA (es) |
| UA (1) | UA112345C2 (es) |
| WO (1) | WO2013139377A1 (es) |
| ZA (1) | ZA201406886B (es) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MX378262B (es) * | 2015-03-31 | 2025-03-10 | Laboratorios Bago S A | Procedimiento de elaboración de pellets entéricos que contienen un inhibidor de la bomba protónica y composiciones farmacéuticas multiparticuladas que los contienen. |
| WO2017084680A1 (en) * | 2015-11-17 | 2017-05-26 | Rontis Hellas S.A. | Pharmaceutical composition containing a non-steroidal antiinflammatory drug and a proton pump inhibitor |
| CN109498571B (zh) * | 2018-11-19 | 2019-09-10 | 朗天药业(湖北)有限公司 | 一种艾司奥美拉唑钠缓释微球及其制备方法 |
| TW202126301A (zh) * | 2019-10-04 | 2021-07-16 | 愛爾蘭商席歐拉斯製藥有限公司 | 小兒懸浮調配物 |
| CN112494450A (zh) * | 2020-12-12 | 2021-03-16 | 海南海神同洲制药有限公司 | 化学药专用口腔崩解片包覆结构及其制备方法 |
| CN115317464B (zh) * | 2022-09-01 | 2023-08-08 | 苏州弘森药业股份有限公司 | 一种双氯芬酸钾微胶囊及其制备方法 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0520119A1 (de) | 1991-06-17 | 1992-12-30 | Spirig Ag Pharmazeutische Präparate | Neue orale Diclofenaczubereitung |
| EP0653935B1 (en) | 1992-08-05 | 2002-05-08 | F.H. FAULDING & CO. LIMITED | Pelletised pharmaceutical composition |
| ES2068762B1 (es) | 1993-07-21 | 1995-12-01 | Lipotec Sa | Un nuevo preparado farmaceutico para mejorar la biodisponibilidad de drogas de dificil absorcion y procedimiento para su obtencion. |
| US6096344A (en) * | 1995-07-28 | 2000-08-01 | Advanced Polymer Systems, Inc. | Bioerodible porous compositions |
| SE9600070D0 (sv) * | 1996-01-08 | 1996-01-08 | Astra Ab | New oral pharmaceutical dosage forms |
| US7687542B2 (en) * | 1996-05-17 | 2010-03-30 | Kowa Pharmaeuticals America, Inc. | Rapidly bioavailable tablet and capsule formulations of diclofenac |
| US6544556B1 (en) * | 2000-09-11 | 2003-04-08 | Andrx Corporation | Pharmaceutical formulations containing a non-steroidal antiinflammatory drug and a proton pump inhibitor |
| AR044398A1 (es) | 2004-05-19 | 2005-09-14 | Bago Sa Labor | Procedimiento para la elaboracion de microcapsulas recubiertas que contienen agentes farmacologicamente activos y composiciones farmaceuticas conteniendo dichas microcapsulas". |
-
2012
- 2012-03-20 PL PL12709640.2T patent/PL2827843T3/pl unknown
- 2012-03-20 BR BR112014023278-4A patent/BR112014023278B1/pt not_active IP Right Cessation
- 2012-03-20 CN CN201280071655.7A patent/CN104244927B/zh not_active Expired - Fee Related
- 2012-03-20 WO PCT/EP2012/054904 patent/WO2013139377A1/en not_active Ceased
- 2012-03-20 US US14/386,377 patent/US9668978B2/en active Active
- 2012-03-20 UA UAA201410294A patent/UA112345C2/uk unknown
- 2012-03-20 ES ES12709640.2T patent/ES2584403T3/es active Active
- 2012-03-20 SG SG11201505320TA patent/SG11201505320TA/en unknown
- 2012-03-20 EP EP12709640.2A patent/EP2827843B1/en active Active
- 2012-03-20 MX MX2014011289A patent/MX354454B/es active IP Right Grant
- 2012-03-20 CA CA2899664A patent/CA2899664C/en active Active
-
2013
- 2013-02-27 AR ARP130100626A patent/AR090187A1/es not_active Application Discontinuation
-
2014
- 2014-09-05 PH PH12014501981A patent/PH12014501981B1/en unknown
- 2014-09-17 CL CL2014002465A patent/CL2014002465A1/es unknown
- 2014-09-19 ZA ZA2014/06886A patent/ZA201406886B/en unknown
-
2016
- 2016-12-27 CL CL2016003348A patent/CL2016003348A1/es unknown
-
2017
- 2017-03-09 US US15/454,127 patent/US9918941B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| SG11201505320TA (en) | 2015-08-28 |
| US20150072000A1 (en) | 2015-03-12 |
| WO2013139377A1 (en) | 2013-09-26 |
| MX354454B (es) | 2018-03-06 |
| MX2014011289A (es) | 2015-02-17 |
| CA2899664C (en) | 2019-07-09 |
| PH12014501981A1 (en) | 2014-11-24 |
| US9668978B2 (en) | 2017-06-06 |
| UA112345C2 (uk) | 2016-08-25 |
| EP2827843A1 (en) | 2015-01-28 |
| CN104244927A (zh) | 2014-12-24 |
| CL2016003348A1 (es) | 2018-03-23 |
| ES2584403T3 (es) | 2016-09-27 |
| US9918941B2 (en) | 2018-03-20 |
| US20170172934A1 (en) | 2017-06-22 |
| CN104244927B (zh) | 2017-03-15 |
| PH12014501981B1 (en) | 2014-11-24 |
| CA2899664A1 (en) | 2013-09-26 |
| AR090187A1 (es) | 2014-10-22 |
| BR112014023278B1 (pt) | 2021-11-16 |
| EP2827843B1 (en) | 2016-05-25 |
| PL2827843T3 (pl) | 2016-11-30 |
| ZA201406886B (en) | 2015-06-24 |
| BR112014023278A2 (es) | 2017-06-20 |
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