CL2015000038A1 - Métodos para preparar triazolopiridinas sustituidas y compuestos intermediarios. - Google Patents

Métodos para preparar triazolopiridinas sustituidas y compuestos intermediarios.

Info

Publication number
CL2015000038A1
CL2015000038A1 CL2015000038A CL2015000038A CL2015000038A1 CL 2015000038 A1 CL2015000038 A1 CL 2015000038A1 CL 2015000038 A CL2015000038 A CL 2015000038A CL 2015000038 A CL2015000038 A CL 2015000038A CL 2015000038 A1 CL2015000038 A1 CL 2015000038A1
Authority
CL
Chile
Prior art keywords
methods
intermediates
preparing substituted
substituted triazolopyridines
triazolopyridines
Prior art date
Application number
CL2015000038A
Other languages
English (en)
Spanish (es)
Inventor
Volker Schulze Dr
Franz-Josef Mais Dr
Original Assignee
Bayer Pharma AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Pharma AG filed Critical Bayer Pharma AG
Publication of CL2015000038A1 publication Critical patent/CL2015000038A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CL2015000038A 2012-07-10 2015-01-08 Métodos para preparar triazolopiridinas sustituidas y compuestos intermediarios. CL2015000038A1 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP12175640 2012-07-10
EP12185590 2012-09-24
EP13170585 2013-06-05

Publications (1)

Publication Number Publication Date
CL2015000038A1 true CL2015000038A1 (es) 2015-03-13

Family

ID=48793197

Family Applications (1)

Application Number Title Priority Date Filing Date
CL2015000038A CL2015000038A1 (es) 2012-07-10 2015-01-08 Métodos para preparar triazolopiridinas sustituidas y compuestos intermediarios.

Country Status (24)

Country Link
US (1) US9388177B2 (2)
EP (1) EP2872506A1 (2)
JP (1) JP6238979B2 (2)
KR (1) KR20150040845A (2)
CN (1) CN104603136B (2)
AP (1) AP3778A (2)
AU (1) AU2013289381A1 (2)
BR (1) BR112015000308A2 (2)
CA (1) CA2878481A1 (2)
CL (1) CL2015000038A1 (2)
CO (1) CO7160002A2 (2)
CR (1) CR20150006A (2)
DO (1) DOP2015000007A (2)
EA (1) EA027544B1 (2)
HK (1) HK1206731A1 (2)
IL (1) IL236265A (2)
IN (1) IN2015DN00085A (2)
MX (1) MX2015000348A (2)
NZ (1) NZ703020A (2)
PE (1) PE20150354A1 (2)
PH (1) PH12015500061A1 (2)
SG (1) SG11201408419QA (2)
TN (1) TN2015000008A1 (2)
WO (1) WO2014009219A1 (2)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2016527193A (ja) * 2013-06-07 2016-09-08 バイエル・ファルマ・アクティエンゲゼルシャフト 置換トリアゾロピリジン
RS56034B1 (sr) * 2013-06-11 2017-09-29 Bayer Pharma AG Derivati prolekova supstituisanih triazolopiridina
HK1219879A1 (zh) 2013-06-11 2017-04-21 Bayer Pharma Aktiengesellschaft 用於治疗癌症的包含mps-1激酶抑制剂和有丝分裂抑制剂的组合
FI3283642T3 (fi) 2015-04-17 2024-01-11 Crossfire Oncology Holding B V Prognostisia biomarkkereita ttk-inhibiittorikemoterapiaan
TW201800408A (zh) 2016-06-15 2018-01-01 拜耳製藥公司 Mps-1抑制劑

Family Cites Families (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPWO2003030937A1 (ja) * 2001-10-05 2005-01-20 小野薬品工業株式会社 ミトコンドリアルベンゾジアゼピン受容体アンタゴニストからなるストレス疾患の治療剤
EP1753428A4 (en) * 2004-05-14 2010-09-15 Abbott Lab INHIBITORS OF KINASES AS THERAPEUTIC AGENTS
UA89503C2 (uk) * 2004-09-13 2010-02-10 Х. Луннбек А/С Заміщені похідні аніліну
WO2006038116A2 (en) * 2004-10-07 2006-04-13 Warner-Lambert Company Llc Triazolopyridine derivatives as antibacterial agents
US20060194823A1 (en) * 2004-12-22 2006-08-31 Georg Kettschau Sulfonamido-macrocycles as Tie2 inhibitors and the salts thereof, a pharmaceutical composition comprising these compounds, the method of preparing and the use thereof
AR061229A1 (es) * 2006-06-06 2008-08-13 Schering Corp Imidazopirazinas como inhibidores de la proteina quinasa
EP1870416A1 (en) * 2006-06-21 2007-12-26 Bayer Schering Pharma Aktiengesellschaft Sulphonamido-macrocycles as tie2 inhibitors
JP5336375B2 (ja) 2006-08-30 2013-11-06 セルゾーム リミテッド キナーゼ阻害剤としてのトリアゾール誘導体
JO3598B1 (ar) * 2006-10-10 2020-07-05 Infinity Discovery Inc الاحماض والاسترات البورونية كمثبطات اميد هيدروليز الحامض الدهني
US8053574B2 (en) 2007-07-18 2011-11-08 Novartis Ag Organic compounds
MX2010002115A (es) 2007-08-23 2010-06-01 Aztrazeneca Ab 2-anilinopurin-8-onas como inhibidores de ttk/mps1 para el tratamiento de trastornos .proliferativos.
CA2691448A1 (en) 2007-08-31 2009-03-05 Dominique Swinnen Triazolopyridine compounds and their use as ask inhibitors
GB0719803D0 (en) 2007-10-10 2007-11-21 Cancer Rec Tech Ltd Therapeutic compounds and their use
GB0724342D0 (en) * 2007-12-13 2008-01-30 Prolysis Ltd Anitbacterial compositions
WO2009137322A2 (en) * 2008-05-05 2009-11-12 The Trustees Of The University Of Pennsylvania Processes for the preparation of biphenyl compounds
EP2303890A4 (en) * 2008-06-19 2012-04-11 Progenics Pharm Inc INHIBITORS OF PHOSPHATIDYLINOSITE-3-KINASE
SG173610A1 (en) 2009-02-13 2011-09-29 Fovea Pharmaceuticals Sa [1, 2, 4] triazolo [1, 5 -a] pyridines as kinase inhibitors
CN102413831B (zh) 2009-04-29 2014-06-04 拜耳知识产权有限责任公司 取代的咪唑并喹喔啉
WO2010141360A1 (en) * 2009-06-05 2010-12-09 Merck Sharp & Dohme Corp. Biaryl benzotriazole derivatives
CN102459258B (zh) * 2009-06-05 2015-11-25 赛福伦公司 1,2,4-三唑并[1,5a]吡啶衍生物的制备和用途
CA2772790C (en) 2009-09-04 2017-06-27 Benjamin Bader Substituted aminoquinoxalines as tyrosine threonine kinase inhibitors
EP2343294A1 (en) * 2009-11-30 2011-07-13 Bayer Schering Pharma AG Substituted triazolopyridines
EP2343295A1 (en) * 2009-11-30 2011-07-13 Bayer Schering Pharma AG Triazolopyridine derivates
EP2343297A1 (en) * 2009-11-30 2011-07-13 Bayer Schering Pharma AG Triazolopyridines
UY33452A (es) * 2010-06-16 2012-01-31 Bayer Schering Pharma Ag Triazolopiridinas sustituidas
WO2012044567A2 (en) * 2010-09-30 2012-04-05 Merck Sharp & Dohme Corp. Imidazole derivatives
HRP20150517T1 (hr) 2011-04-21 2015-06-19 Bayer Intellectual Property Gmbh Triazolopiridini
WO2012160029A1 (en) * 2011-05-23 2012-11-29 Bayer Intellectual Property Gmbh Substituted triazolopyridines
UA112096C2 (uk) * 2011-12-12 2016-07-25 Байєр Інтеллектуал Проперті Гмбх Заміщені триазолопіридини та їх застосування як інгібіторів ttk

Also Published As

Publication number Publication date
EP2872506A1 (en) 2015-05-20
CR20150006A (es) 2015-02-16
SG11201408419QA (en) 2015-01-29
JP2015523372A (ja) 2015-08-13
AP3778A (en) 2016-08-31
BR112015000308A2 (pt) 2017-06-27
MX2015000348A (es) 2015-04-14
PE20150354A1 (es) 2015-03-21
CN104603136A (zh) 2015-05-06
EA027544B1 (ru) 2017-08-31
WO2014009219A1 (en) 2014-01-16
NZ703020A (en) 2017-08-25
US20150148542A1 (en) 2015-05-28
EA201590116A1 (ru) 2015-07-30
CO7160002A2 (es) 2015-01-15
CN104603136B (zh) 2017-06-27
DOP2015000007A (es) 2015-02-15
IL236265A0 (en) 2015-02-26
AU2013289381A1 (en) 2015-01-22
IN2015DN00085A (2) 2015-05-29
AP2014008177A0 (en) 2014-12-31
HK1206731A1 (en) 2016-01-15
KR20150040845A (ko) 2015-04-15
PH12015500061A1 (en) 2015-03-02
JP6238979B2 (ja) 2017-11-29
IL236265A (en) 2017-07-31
CA2878481A1 (en) 2014-01-16
US9388177B2 (en) 2016-07-12
TN2015000008A1 (en) 2016-06-29

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