CL2015003554A1 - Preparado farmacéutico. - Google Patents

Preparado farmacéutico.

Info

Publication number
CL2015003554A1
CL2015003554A1 CL2015003554A CL2015003554A CL2015003554A1 CL 2015003554 A1 CL2015003554 A1 CL 2015003554A1 CL 2015003554 A CL2015003554 A CL 2015003554A CL 2015003554 A CL2015003554 A CL 2015003554A CL 2015003554 A1 CL2015003554 A1 CL 2015003554A1
Authority
CL
Chile
Prior art keywords
solution
alfa
radionucclid
complex
pharmaceutical preparation
Prior art date
Application number
CL2015003554A
Other languages
English (en)
Inventor
Olsen Frenvik Janne
B Ryan Olav
Cuthbertson Alan
Original Assignee
Bayer As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer As filed Critical Bayer As
Publication of CL2015003554A1 publication Critical patent/CL2015003554A1/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04Organic compounds
    • A61K51/08Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A61K51/10Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody
    • A61K51/1075Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody the antibody being against an enzyme
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04Organic compounds
    • A61K51/08Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A61K51/10Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody
    • A61K51/1045Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody against animal or human tumor cells or tumor cell determinants
    • A61K51/1051Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody against animal or human tumor cells or tumor cell determinants the tumor cell being from breast, e.g. the antibody being herceptin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04Organic compounds
    • A61K51/08Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A61K51/10Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody
    • A61K51/1093Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody conjugates with carriers being antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Physics & Mathematics (AREA)
  • Optics & Photonics (AREA)
  • Immunology (AREA)
  • Oncology (AREA)
  • Cell Biology (AREA)
  • Dermatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Dispersion Chemistry (AREA)
  • Nanotechnology (AREA)
  • Engineering & Computer Science (AREA)
  • Extraction Or Liquid Replacement (AREA)
  • Saccharide Compounds (AREA)

Abstract

MÉTODO PARA GENERAR UNA SOLUCIÓN PURIFICADA DE POR LO MENOS UN RADIONÚCLIDO EMISOR ALFA, QUE COMPRENDE PONER EN CONTACTO UNA SOLUCIÓN QUE COMPRENDE DICHO AL MENOS UN COMPLEJO DE RADIONÚCLIDO EMISOR ALFA Y POR LO MENOS UN NÚCLIDO HIJO QUE TIENE POR LO MENOS UN LIGANTE SELECTIVO PARA DICHO POR LO MENOS UN NÚCLIDO HIJO Y SUBSIGUIENTEMENTE SEPARAR DICHA SOLUCIÓN DE POR LO MENOS UN COMPLEJO DE RADIONÚCLIDO EMISOR ALFA DE DICHO POR LO MENOS UN LIGANTE SELECTIVO; MÉTODO PARA REDUCIR LA RADIÓLISIS DE POR LO MENOS UN COMPONENTE ORGÁNICO EN UNA SOLUCIÓN; MÉTODO PARA LA ELIMINACIÓN DE POR LO MENOS UN RADIONÚCLIDO HIJO DE UNA SOLUCIÓN; CONJUNTO DE ELEMENTOS PARA LA FORMACIÓN DE UN PREPARADO FARMACÉUTICO DE POR LO MENOS UN COMPLEJO DE RADIOISÓTOPO EMISOR ALFA; DISPOSITIVO DE ADMINISTRACIÓN; Y MÉTODO PARA FORMAR UNA SOLUCIÓN INYECTABLE DE UN COMPLEJO CON EL ALFA-RADIONÚCLIDO
CL2015003554A 2013-06-05 2015-12-04 Preparado farmacéutico. CL2015003554A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB1310028.4A GB201310028D0 (en) 2013-06-05 2013-06-05 Pharmaceutical preparation

Publications (1)

Publication Number Publication Date
CL2015003554A1 true CL2015003554A1 (es) 2016-07-15

Family

ID=48805787

Family Applications (1)

Application Number Title Priority Date Filing Date
CL2015003554A CL2015003554A1 (es) 2013-06-05 2015-12-04 Preparado farmacéutico.

Country Status (36)

Country Link
US (2) US20160114063A1 (es)
EP (1) EP3003401B1 (es)
JP (1) JP6580559B2 (es)
KR (1) KR102321763B1 (es)
CN (1) CN105592863B (es)
AP (1) AP2015008894A0 (es)
AU (1) AU2014276885B2 (es)
BR (1) BR112015030298A2 (es)
CA (1) CA2914278C (es)
CL (1) CL2015003554A1 (es)
CR (1) CR20150642A (es)
CU (1) CU24535B1 (es)
DK (1) DK3003401T3 (es)
DO (1) DOP2015000294A (es)
EA (1) EA201501174A1 (es)
ES (1) ES2782624T3 (es)
GB (1) GB201310028D0 (es)
HR (1) HRP20200456T1 (es)
IL (1) IL242704B (es)
LT (1) LT3003401T (es)
MA (1) MA38650B1 (es)
MX (1) MX366028B (es)
MY (1) MY180717A (es)
NI (1) NI201500173A (es)
PE (1) PE20160215A1 (es)
PH (1) PH12015502715A1 (es)
PL (1) PL3003401T3 (es)
PT (1) PT3003401T (es)
RS (1) RS60091B1 (es)
SA (1) SA515370233B1 (es)
SG (1) SG11201509856RA (es)
SI (1) SI3003401T1 (es)
TN (1) TN2015000527A1 (es)
UA (1) UA120352C2 (es)
WO (1) WO2014195423A1 (es)
ZA (1) ZA201600027B (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201600161D0 (en) * 2016-01-05 2016-02-17 Bayer As Isotope purification method
GB201600158D0 (en) * 2016-01-05 2016-02-17 Bayer As Purification method
CN114902350A (zh) 2019-12-05 2022-08-12 塞控斯公司 生产高纯度212Pb
WO2022157094A2 (en) 2021-01-22 2022-07-28 Bayer Aktiengesellschaft Lrrc15 antibodies and conjugates thereof
NO347755B1 (en) * 2021-10-21 2024-03-18 Blue Wave Therapeutics Gmbh Peptide-coupled alginate gels comprising radionuclides

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5749042A (en) * 1997-01-28 1998-05-05 Battelle Memorial Institute Bismuth generator method
GB0308731D0 (en) * 2003-04-15 2003-05-21 Anticancer Therapeutic Inv Sa Method of radiotherapy
JP5863640B2 (ja) * 2009-04-29 2016-02-16 バイオ−ラッド ラボラトリーズ インコーポレーティッド 免疫複合体の精製
GB201002508D0 (en) 2010-02-12 2010-03-31 Algeta As Product
GB201105298D0 (en) * 2011-03-29 2011-05-11 Algeta Asa Pharmaceutical preparation

Also Published As

Publication number Publication date
ES2782624T3 (es) 2020-09-15
PT3003401T (pt) 2020-04-09
US20160114063A1 (en) 2016-04-28
SG11201509856RA (en) 2015-12-30
RS60091B1 (sr) 2020-05-29
CN105592863B (zh) 2020-03-10
US20220023449A1 (en) 2022-01-27
KR102321763B1 (ko) 2021-11-05
MY180717A (en) 2020-12-07
PH12015502715B1 (en) 2016-03-28
DOP2015000294A (es) 2016-03-15
NI201500173A (es) 2016-01-06
EP3003401A1 (en) 2016-04-13
TN2015000527A1 (en) 2017-04-06
SA515370233B1 (ar) 2019-05-30
AU2014276885A1 (en) 2015-12-17
KR20160030893A (ko) 2016-03-21
AP2015008894A0 (en) 2015-12-31
PH12015502715A1 (en) 2016-03-28
MA38650B1 (fr) 2019-05-31
SI3003401T1 (sl) 2020-06-30
AU2014276885B2 (en) 2018-12-06
UA120352C2 (uk) 2019-11-25
MX2015016726A (es) 2016-06-28
EP3003401B1 (en) 2020-01-15
CN105592863A (zh) 2016-05-18
BR112015030298A2 (pt) 2017-07-25
JP2016521700A (ja) 2016-07-25
LT3003401T (lt) 2020-06-25
CU20150174A7 (es) 2016-06-29
CR20150642A (es) 2016-07-22
PE20160215A1 (es) 2016-05-22
CA2914278A1 (en) 2014-12-11
HRP20200456T1 (hr) 2020-06-26
EA201501174A1 (ru) 2016-10-31
NZ714737A (en) 2021-02-26
MA38650A1 (fr) 2018-03-30
DK3003401T3 (da) 2020-04-06
CU24535B1 (es) 2021-07-02
CA2914278C (en) 2022-11-01
ZA201600027B (en) 2018-07-25
MX366028B (es) 2019-06-21
WO2014195423A1 (en) 2014-12-11
PL3003401T3 (pl) 2020-07-27
GB201310028D0 (en) 2013-07-17
JP6580559B2 (ja) 2019-09-25
IL242704B (en) 2020-06-30

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