MA38650A1 - Procede de preparation d'une solution purifiee d'au moins un complexe de radionucleide emetteur alpha - Google Patents
Procede de preparation d'une solution purifiee d'au moins un complexe de radionucleide emetteur alphaInfo
- Publication number
- MA38650A1 MA38650A1 MA38650A MA38650A MA38650A1 MA 38650 A1 MA38650 A1 MA 38650A1 MA 38650 A MA38650 A MA 38650A MA 38650 A MA38650 A MA 38650A MA 38650 A1 MA38650 A1 MA 38650A1
- Authority
- MA
- Morocco
- Prior art keywords
- radionuclide complex
- solution
- preparation
- purified solution
- emitting radionuclide
- Prior art date
Links
- OFHCOWSQAMBJIW-AVJTYSNKSA-N alfacalcidol Chemical compound C1(/[C@@H]2CC[C@@H]([C@]2(CCC1)C)[C@H](C)CCCC(C)C)=C\C=C1\C[C@@H](O)C[C@H](O)C1=C OFHCOWSQAMBJIW-AVJTYSNKSA-N 0.000 title abstract 3
- 239000011230 binding agent Substances 0.000 abstract 3
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
- A61K51/10—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody
- A61K51/1075—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody the antibody being against an enzyme
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
- A61K51/10—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody
- A61K51/1045—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody against animal or human tumor cells or tumor cell determinants
- A61K51/1051—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody against animal or human tumor cells or tumor cell determinants the tumor cell being from breast, e.g. the antibody being herceptin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
- A61K51/10—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody
- A61K51/1093—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody conjugates with carriers being antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Physics & Mathematics (AREA)
- Optics & Photonics (AREA)
- Immunology (AREA)
- Oncology (AREA)
- Cell Biology (AREA)
- Dermatology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Dispersion Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Nanotechnology (AREA)
- Saccharide Compounds (AREA)
- Extraction Or Liquid Replacement (AREA)
Abstract
La présente invention concerne un procédé permettant de générer une solution purifiée d'au moins un complexe de radionucléide émetteur alpha. Le procédé comprend la mise en contact d'une solution du complexe de radionucléide émetteur alpha et d'au moins un nucléide fille avec au moins un liant sélectif pour le nucléide fille et, ensuite, la séparation de la solution et du liant sélectif. L'invention concerne également un procédé permettant le retrait d'au moins un radionucléide fille d'une solution comprenant au moins un complexe de radionucléide émetteur alpha. Le procédé comprend la mise en contact de la solution avec au moins un liant pour le nucléide fille.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB1310028.4A GB201310028D0 (en) | 2013-06-05 | 2013-06-05 | Pharmaceutical preparation |
| PCT/EP2014/061743 WO2014195423A1 (fr) | 2013-06-05 | 2014-06-05 | Préparation pharmaceutique |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MA38650A1 true MA38650A1 (fr) | 2018-03-30 |
| MA38650B1 MA38650B1 (fr) | 2019-05-31 |
Family
ID=48805787
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MA38650A MA38650B1 (fr) | 2013-06-05 | 2014-06-05 | Procede de preparation d'une solution purifiee d'au moins un complexe de radionucleide emetteur alpha |
Country Status (36)
| Country | Link |
|---|---|
| US (2) | US20160114063A1 (fr) |
| EP (1) | EP3003401B1 (fr) |
| JP (1) | JP6580559B2 (fr) |
| KR (1) | KR102321763B1 (fr) |
| CN (1) | CN105592863B (fr) |
| AP (1) | AP2015008894A0 (fr) |
| AU (1) | AU2014276885B2 (fr) |
| BR (1) | BR112015030298A2 (fr) |
| CA (1) | CA2914278C (fr) |
| CL (1) | CL2015003554A1 (fr) |
| CR (1) | CR20150642A (fr) |
| CU (1) | CU24535B1 (fr) |
| DK (1) | DK3003401T3 (fr) |
| DO (1) | DOP2015000294A (fr) |
| EA (1) | EA201501174A1 (fr) |
| ES (1) | ES2782624T3 (fr) |
| GB (1) | GB201310028D0 (fr) |
| HR (1) | HRP20200456T1 (fr) |
| IL (1) | IL242704B (fr) |
| LT (1) | LT3003401T (fr) |
| MA (1) | MA38650B1 (fr) |
| MX (1) | MX366028B (fr) |
| MY (1) | MY180717A (fr) |
| NI (1) | NI201500173A (fr) |
| PE (1) | PE20160215A1 (fr) |
| PH (1) | PH12015502715A1 (fr) |
| PL (1) | PL3003401T3 (fr) |
| PT (1) | PT3003401T (fr) |
| RS (1) | RS60091B1 (fr) |
| SA (1) | SA515370233B1 (fr) |
| SG (1) | SG11201509856RA (fr) |
| SI (1) | SI3003401T1 (fr) |
| TN (1) | TN2015000527A1 (fr) |
| UA (1) | UA120352C2 (fr) |
| WO (1) | WO2014195423A1 (fr) |
| ZA (1) | ZA201600027B (fr) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB201600161D0 (en) * | 2016-01-05 | 2016-02-17 | Bayer As | Isotope purification method |
| GB201600158D0 (en) * | 2016-01-05 | 2016-02-17 | Bayer As | Purification method |
| JP7544819B2 (ja) | 2019-12-05 | 2024-09-03 | サイエンコンス アクスイェ セルスカプ | 高度に精製された２１２Ｐｂの製造 |
| CN116745323A (zh) | 2021-01-22 | 2023-09-12 | 拜耳股份有限公司 | Lrrc15抗体及其缀合物 |
| NO347755B1 (en) * | 2021-10-21 | 2024-03-18 | Blue Wave Therapeutics Gmbh | Peptide-coupled alginate gels comprising radionuclides |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5749042A (en) * | 1997-01-28 | 1998-05-05 | Battelle Memorial Institute | Bismuth generator method |
| GB0308731D0 (en) * | 2003-04-15 | 2003-05-21 | Anticancer Therapeutic Inv Sa | Method of radiotherapy |
| EP2424875B1 (fr) * | 2009-04-29 | 2016-01-06 | Bio-Rad Laboratories, Inc. | Purification d'immunoconjugués |
| GB201002508D0 (en) | 2010-02-12 | 2010-03-31 | Algeta As | Product |
| GB201105298D0 (en) * | 2011-03-29 | 2011-05-11 | Algeta Asa | Pharmaceutical preparation |
-
2013
- 2013-06-05 GB GBGB1310028.4A patent/GB201310028D0/en not_active Ceased
-
2014
- 2014-06-05 UA UAA201512920A patent/UA120352C2/uk unknown
- 2014-06-05 LT LTEP14728571.2T patent/LT3003401T/lt unknown
- 2014-06-05 CN CN201480044621.8A patent/CN105592863B/zh not_active Expired - Fee Related
- 2014-06-05 KR KR1020157036893A patent/KR102321763B1/ko not_active Expired - Fee Related
- 2014-06-05 PT PT147285712T patent/PT3003401T/pt unknown
- 2014-06-05 PL PL14728571T patent/PL3003401T3/pl unknown
- 2014-06-05 CA CA2914278A patent/CA2914278C/fr active Active
- 2014-06-05 SI SI201431535T patent/SI3003401T1/sl unknown
- 2014-06-05 WO PCT/EP2014/061743 patent/WO2014195423A1/fr not_active Ceased
- 2014-06-05 DK DK14728571.2T patent/DK3003401T3/da active
- 2014-06-05 MY MYPI2015704399A patent/MY180717A/en unknown
- 2014-06-05 MX MX2015016726A patent/MX366028B/es active IP Right Grant
- 2014-06-05 TN TN2015000527A patent/TN2015000527A1/en unknown
- 2014-06-05 CU CU2015000174A patent/CU24535B1/es unknown
- 2014-06-05 BR BR112015030298A patent/BR112015030298A2/pt active Search and Examination
- 2014-06-05 RS RS20200349A patent/RS60091B1/sr unknown
- 2014-06-05 US US14/896,424 patent/US20160114063A1/en not_active Abandoned
- 2014-06-05 AU AU2014276885A patent/AU2014276885B2/en not_active Ceased
- 2014-06-05 SG SG11201509856RA patent/SG11201509856RA/en unknown
- 2014-06-05 PE PE2015002566A patent/PE20160215A1/es unknown
- 2014-06-05 EP EP14728571.2A patent/EP3003401B1/fr active Active
- 2014-06-05 HR HRP20200456TT patent/HRP20200456T1/hr unknown
- 2014-06-05 MA MA38650A patent/MA38650B1/fr unknown
- 2014-06-05 AP AP2015008894A patent/AP2015008894A0/xx unknown
- 2014-06-05 JP JP2016517608A patent/JP6580559B2/ja not_active Expired - Fee Related
- 2014-06-05 EA EA201501174A patent/EA201501174A1/ru unknown
- 2014-06-05 ES ES14728571T patent/ES2782624T3/es active Active
-
2015
- 2015-11-22 IL IL242704A patent/IL242704B/en active IP Right Grant
- 2015-12-03 SA SA515370233A patent/SA515370233B1/ar unknown
- 2015-12-04 CR CR20150642A patent/CR20150642A/es unknown
- 2015-12-04 CL CL2015003554A patent/CL2015003554A1/es unknown
- 2015-12-04 PH PH12015502715A patent/PH12015502715A1/en unknown
- 2015-12-04 DO DO2015000294A patent/DOP2015000294A/es unknown
- 2015-12-04 NI NI201500173A patent/NI201500173A/es unknown
-
2016
- 2016-01-04 ZA ZA2016/00027A patent/ZA201600027B/en unknown
-
2021
- 2021-05-04 US US17/307,857 patent/US20220023449A1/en not_active Abandoned
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