CL2016000906A1 - Suplementación de nucleósidos para promover la función celular, la estabilidad genética y aplicaciones regenerativas - Google Patents

Suplementación de nucleósidos para promover la función celular, la estabilidad genética y aplicaciones regenerativas

Info

Publication number
CL2016000906A1
CL2016000906A1 CL2016000906A CL2016000906A CL2016000906A1 CL 2016000906 A1 CL2016000906 A1 CL 2016000906A1 CL 2016000906 A CL2016000906 A CL 2016000906A CL 2016000906 A CL2016000906 A CL 2016000906A CL 2016000906 A1 CL2016000906 A1 CL 2016000906A1
Authority
CL
Chile
Prior art keywords
supplementation
nucleoside
cell function
promote cell
genetic stability
Prior art date
Application number
CL2016000906A
Other languages
English (en)
Inventor
James A Byrne
Caius Radu
Patrick Lee
Original Assignee
Univ California
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ California filed Critical Univ California
Publication of CL2016000906A1 publication Critical patent/CL2016000906A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0696—Artificially induced pluripotent stem cells, e.g. iPS
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/48—Reproductive organs
    • A61K35/54—Ovaries; Ova; Ovules; Embryos; Foetal cells; Germ cells
    • A61K35/545—Embryonic stem cells; Pluripotent stem cells; Induced pluripotent stem cells; Uncharacterised stem cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/10—Anti-acne agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/16—Emollients or protectives, e.g. against radiation
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/30—Organic components
    • C12N2500/40—Nucleotides, nucleosides or bases
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/98—Xeno-free medium and culture conditions

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Cell Biology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dermatology (AREA)
  • Transplantation (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Reproductive Health (AREA)
  • Gynecology & Obstetrics (AREA)
  • Immunology (AREA)
  • Virology (AREA)
  • Toxicology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Materials For Medical Uses (AREA)
  • Cosmetics (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CL2016000906A 2013-10-16 2016-04-15 Suplementación de nucleósidos para promover la función celular, la estabilidad genética y aplicaciones regenerativas CL2016000906A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201361891846P 2013-10-16 2013-10-16

Publications (1)

Publication Number Publication Date
CL2016000906A1 true CL2016000906A1 (es) 2017-02-03

Family

ID=52810178

Family Applications (1)

Application Number Title Priority Date Filing Date
CL2016000906A CL2016000906A1 (es) 2013-10-16 2016-04-15 Suplementación de nucleósidos para promover la función celular, la estabilidad genética y aplicaciones regenerativas

Country Status (10)

Country Link
US (1) US20150105343A1 (es)
EP (1) EP3058061A4 (es)
JP (1) JP2016538836A (es)
KR (1) KR20160062764A (es)
CN (1) CN105849251A (es)
BR (1) BR112016008538A2 (es)
CA (1) CA2927355A1 (es)
CL (1) CL2016000906A1 (es)
IL (1) IL245111A0 (es)
WO (1) WO2015057997A1 (es)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20180245048A1 (en) * 2015-02-25 2018-08-30 Agency For Science, Technology And Research Methods and compositions for expansion and differentiation of skeletal muscle stem cells or progenitor cells
WO2016168735A1 (en) * 2015-04-15 2016-10-20 The Regents Of The University Of California Nucleoside supplementation to promote cellular function, genetic stability and augment transgenic expression
DK3305891T3 (da) * 2015-05-27 2021-01-25 Astellas Pharma Inc Celledyrkningsfremgangsmåde som anvender nukleinsyre-holdigt medium
KR102537361B1 (ko) * 2016-12-27 2023-05-26 스미또모 가가꾸 가부시키가이샤 인공 다능성 줄기 세포의 평가 방법 및 선발 방법, 그리고 인공 다능성 줄기 세포의 제조 방법
CN110331130B (zh) * 2019-07-03 2021-02-05 依科赛生物科技（太仓）有限公司 一种间充质干细胞无血清培养基及其用途
CN110339118B (zh) * 2019-08-19 2022-08-16 广州明辉化妆品有限公司 具有美白保湿功效的美白霜
CN115078233A (zh) * 2022-07-21 2022-09-20 合肥源恩生物技术有限公司 一种利用流式细胞术检测细胞功能的方法
WO2024259051A1 (en) * 2023-06-14 2024-12-19 The Children's Medical Center Corporation Systems and methods for modifying a polynucleotide

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2307807C (en) * 1997-10-23 2008-09-02 Andrea G. Bodnar Methods and materials for the growth of primate-derived primordial stem cells in feeder-free culture
US20060286668A1 (en) * 1999-04-30 2006-12-21 Invitrogen Corporation Animal-cell culture media comprising non-animal or plant-derived nutrients
CA2563872C (en) * 2004-05-07 2014-11-25 Wisconsin Alumni Research Foundation Method of forming mesenchymal stem cells from embryonic stem cells
ES2352046T3 (es) * 2007-09-21 2011-02-15 Universität Leipzig Medio de cultivo celular y procedimiento de cultivo de células madre y células progenitor.
KR101220239B1 (ko) * 2008-04-01 2013-01-09 바이오스펙트럼 주식회사 식물성 펩톤을 포함하는 줄기세포 증식 촉진용 조성물

Also Published As

Publication number Publication date
CN105849251A (zh) 2016-08-10
EP3058061A1 (en) 2016-08-24
US20150105343A1 (en) 2015-04-16
CA2927355A1 (en) 2015-04-23
IL245111A0 (en) 2016-06-30
JP2016538836A (ja) 2016-12-15
BR112016008538A2 (pt) 2019-06-11
WO2015057997A1 (en) 2015-04-23
KR20160062764A (ko) 2016-06-02
EP3058061A4 (en) 2017-04-12

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