CL2016001095A1 - Silicato de zirconio microporoso para el tratamiento de hipercalemia. - Google Patents

Silicato de zirconio microporoso para el tratamiento de hipercalemia.

Info

Publication number
CL2016001095A1
CL2016001095A1 CL2016001095A CL2016001095A CL2016001095A1 CL 2016001095 A1 CL2016001095 A1 CL 2016001095A1 CL 2016001095 A CL2016001095 A CL 2016001095A CL 2016001095 A CL2016001095 A CL 2016001095A CL 2016001095 A1 CL2016001095 A1 CL 2016001095A1
Authority
CL
Chile
Prior art keywords
hyperkalemia
treatment
zirconium silicate
microporous zirconium
microporous
Prior art date
Application number
CL2016001095A
Other languages
English (en)
Inventor
Donald Jeffrey Keyser
Alvaro F Guillem
Original Assignee
Zs Pharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=53042126&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CL2016001095(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Zs Pharma Inc filed Critical Zs Pharma Inc
Publication of CL2016001095A1 publication Critical patent/CL2016001095A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/08—Plasma substitutes; Perfusion solutions; Dialytics or haemodialytics; Drugs for electrolytic or acid-base disorders, e.g. hypovolemic shock
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10—Antioedematous agents; Diuretics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/02—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof comprising inorganic material
    • B01J20/10—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof comprising inorganic material comprising silica or silicate
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J39/00—Cation exchange; Use of material as cation exchangers; Treatment of material for improving the cation exchange properties
    • B01J39/08—Use of material as cation exchangers; Treatment of material for improving the cation exchange properties
    • B01J39/14—Base exchange silicates, e.g. zeolites

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Inorganic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Analytical Chemistry (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Obesity (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

UNA COMPOSICION QUE COMPRENDE SILICATO DE CIRCONIO, EN DONDE LA COMPOSICION COMPRENDE AL MENOS 95% DE LA FORMA CRISTALINA ZS-9, UTIL PARA EL TRATAMIENTO DE HIPERKALEMIA.
CL2016001095A 2013-11-08 2016-05-06 Silicato de zirconio microporoso para el tratamiento de hipercalemia. CL2016001095A1 (es)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201361901886P 2013-11-08 2013-11-08
US201361914354P 2013-12-10 2013-12-10
US201461930328P 2014-01-22 2014-01-22
US201461930336P 2014-01-22 2014-01-22
US201462005484P 2014-05-30 2014-05-30
US201462015215P 2014-06-20 2014-06-20
US201462053732P 2014-09-22 2014-09-22

Publications (1)

Publication Number Publication Date
CL2016001095A1 true CL2016001095A1 (es) 2016-11-11

Family

ID=53042126

Family Applications (1)

Application Number Title Priority Date Filing Date
CL2016001095A CL2016001095A1 (es) 2013-11-08 2016-05-06 Silicato de zirconio microporoso para el tratamiento de hipercalemia.

Country Status (14)

Country Link
US (2) US20150290242A1 (es)
EP (2) EP4378577A3 (es)
JP (1) JP2016535754A (es)
KR (1) KR102332954B1 (es)
CN (1) CN106170283B (es)
AU (1) AU2014346576B2 (es)
CA (1) CA2929978C (es)
CL (1) CL2016001095A1 (es)
IL (1) IL245526B (es)
MX (1) MX392710B (es)
PH (1) PH12016500864A1 (es)
TW (1) TW201607543A (es)
WO (1) WO2015070019A1 (es)
ZA (1) ZA201603171B (es)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20160038538A1 (en) * 2013-11-08 2016-02-11 ZS Pharma, Inc. Microporous zirconium silicate for the treatment of hyperkalemia
US9592253B1 (en) * 2015-10-14 2017-03-14 ZS Pharma, Inc. Extended use zirconium silicate compositions and methods of use thereof
US10668098B2 (en) * 2017-07-07 2020-06-02 Hemocleanse Technology Llc Oral sorbent for removing toxins of kidney failure combining anion and cation exchangers
AU2018360868B2 (en) * 2017-11-03 2025-01-02 Tricida, Inc. Method of treating acid-base disorders
WO2019092179A1 (en) * 2017-11-10 2019-05-16 Sandoz Ag Pharmaceutical compositions comprising zs-9
BR112021017791A2 (pt) * 2019-03-13 2022-02-01 Astrazeneca Ab Agentes de ligação ao potássio para uso em pacientes em hemodiálise
US20240000940A1 (en) * 2020-12-01 2024-01-04 Nanobiotix S.A. Porous, high-z and carbon-free particles as radioenhancers
CN117342570B (zh) * 2023-09-04 2026-02-10 杭州国瑞生物科技有限公司 一种环硅酸锆钠的a晶型及其制备方法
CN117735564B (zh) * 2023-12-19 2025-12-19 杭州国瑞生物科技有限公司 一种环硅酸锆钠的b晶型及其制备方法与应用
CN118458789A (zh) * 2024-05-11 2024-08-09 上海博悦生物科技有限公司 一种环硅酸锆钠相关晶型zs-7的制备方法
CN120172420B (zh) * 2025-03-21 2025-12-23 时森海(杭州)医药科技有限公司 控制粒径分布的环硅酸锆钠及其制备方法
CN120984211A (zh) * 2025-06-13 2025-11-21 时森海(杭州)医药科技有限公司 生产环硅酸锆钠的反应器和方法

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3329480A (en) * 1963-10-18 1967-07-04 Union Oil Co Crystalline zircono-silicate zeolites
US4581141A (en) * 1978-02-27 1986-04-08 Purdue Research Foundation Dialysis material and method for removing uremic substances
JP3310282B2 (ja) * 1990-05-28 2002-08-05 エンゲルハード・コーポレーシヨン 少なくとも１個の正八面体部位と少なくとも１種の型の正四面体部位とを有する大孔モレキュラーシーブ
US5338527A (en) * 1992-08-20 1994-08-16 Uop Zirconium silicate composition, method of preparation and uses thereof
US5888472A (en) * 1997-04-08 1999-03-30 Uop Llc Zirconium silicate molecular sieves and process using the same
US5891417A (en) * 1997-04-08 1999-04-06 Uop Llc Zirconium silicate and zirconium germanate molecular sieves and process using the same
EP1038580B1 (en) * 1999-03-26 2005-05-25 Uop Llc Ammonium ion adsorption process using zirconium silicate and zirconium germanate molecular sieves
US6099737A (en) 1999-03-29 2000-08-08 Uop Llc Process for removing toxins from blood using zirconium metallate or titanium metallate compositions
US6332985B1 (en) * 1999-03-29 2001-12-25 Uop Llc Process for removing toxins from bodily fluids using zirconium or titanium microporous compositions
AU2002242103A1 (en) * 2001-02-06 2002-08-19 Ash Medical Systems, Inc. Monovalent-selective cation exchangers as oral sorbent therapy
US6579460B1 (en) 2001-03-13 2003-06-17 Uop Llc Process and composition for removing toxins from bodily fluids
US6814871B1 (en) 2001-07-13 2004-11-09 Uop Llc Process for removing pollutants from aqueous streams
US7556799B2 (en) * 2004-03-30 2009-07-07 Relypsa, Inc. Ion binding polymers and uses thereof
WO2010144865A2 (en) * 2009-06-12 2010-12-16 Meritage Pharma, Inc. Methods for treating gastrointestinal disorders
SI2673237T2 (sl) * 2011-02-11 2025-12-31 Zs Pharma, Inc Uporaba cirkonijevega silikata v zdravljenju hiperkalemije
US9943637B2 (en) 2012-06-11 2018-04-17 ZS Pharma, Inc. Microporous zirconium silicate and its method of production
CN104968336A (zh) * 2012-07-11 2015-10-07 Zs制药公司 用于治疗高钙血症患者高钾血症的微孔硅酸锆以及用于治疗高钾血症的改进的含钙组合物
CN104797263B (zh) * 2012-10-22 2018-02-09 Zs制药公司 用于治疗高钾血症的微孔硅酸锆

Also Published As

Publication number Publication date
TW201607543A (zh) 2016-03-01
JP2016535754A (ja) 2016-11-17
MX392710B (es) 2025-03-24
WO2015070019A1 (en) 2015-05-14
IL245526A0 (en) 2016-06-30
CN106170283A (zh) 2016-11-30
AU2014346576A1 (en) 2016-06-09
EP3065710A4 (en) 2017-05-17
EP4378577A2 (en) 2024-06-05
EP3065710A1 (en) 2016-09-14
IL245526B (en) 2020-01-30
CA2929978C (en) 2021-11-30
CN106170283B (zh) 2019-08-20
KR102332954B1 (ko) 2021-11-29
EP4378577A3 (en) 2024-10-23
AU2014346576B2 (en) 2020-03-26
ZA201603171B (en) 2020-11-25
KR20160073424A (ko) 2016-06-24
MX2016005940A (es) 2016-08-17
US20150290242A1 (en) 2015-10-15
CA2929978A1 (en) 2015-05-14
US20150374748A1 (en) 2015-12-31
PH12016500864A1 (en) 2016-07-18

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