CL2016001580A1 - Uso de compuestos derivados de indol para tratar una infección por flavivirus; compuestos derivados de indol; composiciones farmacéuticas; y uso de una combinación. - Google Patents

Uso de compuestos derivados de indol para tratar una infección por flavivirus; compuestos derivados de indol; composiciones farmacéuticas; y uso de una combinación.

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Publication number
CL2016001580A1
CL2016001580A1 CL2016001580A CL2016001580A CL2016001580A1 CL 2016001580 A1 CL2016001580 A1 CL 2016001580A1 CL 2016001580 A CL2016001580 A CL 2016001580A CL 2016001580 A CL2016001580 A CL 2016001580A CL 2016001580 A1 CL2016001580 A1 CL 2016001580A1
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CL
Chile
Prior art keywords
indole
derived compounds
treat
combination
pharmaceutical compositions
Prior art date
Application number
CL2016001580A
Other languages
English (en)
Inventor
Dorothée Bardiot
Gunter Carlens
Kai Dallmeier
Suzanne Kaptein
Michael Mcnaughton
Arnaud Marchand
Johan Neyts
Wim Smets
Original Assignee
Univ Leuven Kath
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=44993373&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CL2016001580(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Univ Leuven Kath filed Critical Univ Leuven Kath
Publication of CL2016001580A1 publication Critical patent/CL2016001580A1/es

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    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
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    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
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    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
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    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
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    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
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    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
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    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
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  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Virology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Indole Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)

Abstract

<p>COMPUESTOS DERIVADOS DE INDOL SUSTITUIDOS; Y USO DE COMPUESTOS DERIVADOS DE INDOL SUSTITUIDOS PARA TRATAR UNA INFECCION POR UN FLAVIVIRUS TAL COMO LA INFECCION POR UN VIRUS DEL DENGUE, VIRUS DEL NILO OCCIDENTAL, VIRUS DE LA ENCEFALITIS POR GARRAPATAS Y VIRUS DE LA FIEBRE AMARILLA.</p>
CL2016001580A 2011-09-26 2016-06-17 Uso de compuestos derivados de indol para tratar una infección por flavivirus; compuestos derivados de indol; composiciones farmacéuticas; y uso de una combinación. CL2016001580A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201161626410P 2011-09-26 2011-09-26
GBGB1116559.4A GB201116559D0 (en) 2011-09-26 2011-09-26 Novel viral replication inhibitors

Publications (1)

Publication Number Publication Date
CL2016001580A1 true CL2016001580A1 (es) 2017-01-13

Family

ID=44993373

Family Applications (2)

Application Number Title Priority Date Filing Date
CL2014000732A CL2014000732A1 (es) 2011-09-26 2014-03-25 Compuestos derivados heterociclicos para su uso en la prevencion o tratamiento de una infeccion por flavivirus; metodo para su preparacion; y composicion farmaceutica que los comprende.
CL2016001580A CL2016001580A1 (es) 2011-09-26 2016-06-17 Uso de compuestos derivados de indol para tratar una infección por flavivirus; compuestos derivados de indol; composiciones farmacéuticas; y uso de una combinación.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
CL2014000732A CL2014000732A1 (es) 2011-09-26 2014-03-25 Compuestos derivados heterociclicos para su uso en la prevencion o tratamiento de una infeccion por flavivirus; metodo para su preparacion; y composicion farmaceutica que los comprende.

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US (3) US10550123B2 (es)
EP (2) EP2760831B1 (es)
JP (2) JP6266521B2 (es)
KR (2) KR102081444B1 (es)
CN (2) CN108440370B (es)
AP (1) AP2014070535A0 (es)
AU (3) AU2012314498B2 (es)
BR (1) BR112014007134B1 (es)
CA (1) CA2848604C (es)
CL (2) CL2014000732A1 (es)
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CR (1) CR20140147A (es)
CY (1) CY1122291T1 (es)
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US8563573B2 (en) 2007-11-02 2013-10-22 Vertex Pharmaceuticals Incorporated Azaindole derivatives as CFTR modulators
US8802868B2 (en) 2010-03-25 2014-08-12 Vertex Pharmaceuticals Incorporated Solid forms of (R)-1(2,2-difluorobenzo[D][1,3]dioxo1-5-yl)-N-(1-(2,3-dihydroxypropyl-6-fluoro-2-(1-hydroxy-2-methylpropan2-yl)-1H-Indol-5-yl)-Cyclopropanecarboxamide
MX353408B (es) 2010-04-22 2018-01-11 Vertex Pharma Proceso para producir compuestos de cicloalquilcarboxamido-indol.
GB201116559D0 (en) 2011-09-26 2011-11-09 Univ Leuven Kath Novel viral replication inhibitors
GB201305376D0 (en) 2013-03-25 2013-05-08 Univ Leuven Kath Novel viral replication inhibitors
RU2744460C2 (ru) 2014-04-15 2021-03-09 Вертекс Фармасьютикалз Инкорпорейтед Фармацевтические композиции для лечения заболеваний, опосредованных муковисцидозным трансмембранным регулятором проводимости
AU2015326930B2 (en) * 2014-10-01 2020-03-26 Janssen Pharmaceuticals, Inc. Mono- or di-substituted indole derivatives as dengue viral replication inhibitors
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