CL2016003055A1 - Sistema gastroretentivo expandible de liberación de medicamentos - Google Patents

Sistema gastroretentivo expandible de liberación de medicamentos

Info

Publication number
CL2016003055A1
CL2016003055A1 CL2016003055A CL2016003055A CL2016003055A1 CL 2016003055 A1 CL2016003055 A1 CL 2016003055A1 CL 2016003055 A CL2016003055 A CL 2016003055A CL 2016003055 A CL2016003055 A CL 2016003055A CL 2016003055 A1 CL2016003055 A1 CL 2016003055A1
Authority
CL
Chile
Prior art keywords
delivery system
drug delivery
gastroretentive drug
expandable
expandable gastroretentive
Prior art date
Application number
CL2016003055A
Other languages
English (en)
Inventor
Avshalom Ben Menachem
Ilan Zalit
Original Assignee
Teva Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Teva Pharma filed Critical Teva Pharma
Publication of CL2016003055A1 publication Critical patent/CL2016003055A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0065—Forms with gastric retention, e.g. floating on gastric juice, adhering to gastric mucosa, expanding to prevent passage through the pylorus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M31/00—Devices for introducing or retaining media, e.g. remedies, in cavities of the body
    • A61M31/002—Devices for releasing a drug at a continuous and controlled rate for a prolonged period of time

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Molecular Biology (AREA)
  • Anesthesiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Medicinal Preparation (AREA)
  • Surgical Instruments (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

<p>SE PROPORCIONA UN DISPOSITIVO DE ENTREGA DE FARMACOS GASTRORRETENTIVOS ORALES, LOS CUALES SE DESPLIEGAN RAPIDAMENTE AL CONTACTO CON LOS JUGOS GÁSTRICOS, EL DISPOSITIVO ESTA CONFIGURADO EN UNA CONFIGURACION PLEGADA PARA SU INGESTA ORAL Y DESPLEGADA PARA UNA RETENCION GASTRICA DURANTE UN PERIODO DE TIEMPO PREDETERMINADO Y ASI REDUCIR EVENTUALMENTE EL TAMAÑO PARA SU PASO A TRAVES DEL RESTO DEL TRACTO GASTROINTESTINAL.</p>
CL2016003055A 2014-06-02 2016-11-28 Sistema gastroretentivo expandible de liberación de medicamentos CL2016003055A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201462006541P 2014-06-02 2014-06-02
US201462093763P 2014-12-18 2014-12-18

Publications (1)

Publication Number Publication Date
CL2016003055A1 true CL2016003055A1 (es) 2017-07-28

Family

ID=54700510

Family Applications (1)

Application Number Title Priority Date Filing Date
CL2016003055A CL2016003055A1 (es) 2014-06-02 2016-11-28 Sistema gastroretentivo expandible de liberación de medicamentos

Country Status (13)

Country Link
US (7) US10485758B2 (es)
EP (1) EP3148514B1 (es)
JP (1) JP6570043B2 (es)
KR (1) KR20170015389A (es)
CN (1) CN106535878B (es)
AU (1) AU2015271808A1 (es)
BR (1) BR112016028180A2 (es)
CA (1) CA2949372C (es)
CL (1) CL2016003055A1 (es)
IL (2) IL248939B (es)
MX (1) MX2016015891A (es)
RU (1) RU2016151697A (es)
WO (1) WO2015187746A1 (es)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2015187746A1 (en) * 2014-06-02 2015-12-10 Teva Pharmaceutical Industries Ltd. Expandable gastroretentive dosage form
NZ727659A (en) 2014-06-11 2021-12-24 Massachusetts Inst Technology Residence structures and related methods
AU2016272089B2 (en) 2015-06-03 2021-02-18 Triastek, Inc. Dosage forms and use thereof
US11576859B2 (en) 2015-10-23 2023-02-14 Lyndra Therapeutics, Inc. Gastric residence systems for sustained release of therapeutic agents and methods of use thereof
CA3006999A1 (en) * 2015-12-01 2017-06-08 Clexio Biosciences Ltd. Gastric retentive devices
CA3007165A1 (en) 2015-12-02 2017-06-08 Clexio Biosciences Ltd. Device for preparing gastroretentive dosage forms
WO2017100367A1 (en) * 2015-12-08 2017-06-15 Lyndra, Inc. Geometric configurations for gastric residence systems
CN109310639A (zh) * 2016-05-27 2019-02-05 林德拉有限公司 用于胃驻留系统的材料结构
JP2019532947A (ja) 2016-09-30 2019-11-14 リンドラ，インコーポレイティド アダマンタン系薬物の持続的送達のための胃内滞留システム
CN110035718B (zh) * 2016-12-02 2021-04-06 克雷西奥生物科技有限公司 胃内滞留系统
EP3573602A4 (en) 2017-01-26 2020-09-16 Triastek, Inc. DOSAGE FORMS OF CONTROLLED RELEASE AT SPECIFIC GASTROINTESTINAL SITES
CA3066658A1 (en) 2017-06-09 2018-12-13 Lyndra, Inc. Gastric residence systems with release rate-modulating films
WO2019111132A1 (en) 2017-12-04 2019-06-13 Clexio Biosciences Ltd. Long acting gastric residence system
ES2947662T3 (es) 2017-12-18 2023-08-16 Biograil ApS Administración oral de sustancias farmacológicas activas
CN116270513A (zh) 2018-01-09 2023-06-23 南京三迭纪医药科技有限公司 一种包含固定剂量adhd非兴奋剂和adhd兴奋剂的复方口服药物剂型
US12377242B2 (en) 2018-08-20 2025-08-05 Memory Metal Holland Bv Tubing for manufacturing expandable devices
US12303659B2 (en) * 2018-11-15 2025-05-20 Massachusetts Institute Of Technology Thermally controlled reconfigurable medical devices
AU2020242062B2 (en) * 2019-03-20 2025-12-11 Nortiva Bio, Inc. Coatings for gastric residence dosage forms
BR112021018496A2 (pt) * 2019-03-20 2021-11-30 Lyndra Therapeutics Inc Cápsulas e revestimento de cápsula para formas de dosagem de residência gástrica
US11389398B2 (en) 2019-05-14 2022-07-19 Clexio Biosciences Ltd. Gastroretentive treatment of nocturnal symptoms and morning akinesia in subjects with parkinson's disease
JP7847119B2 (ja) * 2020-07-29 2026-04-16 ザ・セカント・グループ・エルエルシー 架橋ポリ（セバシン酸グリセロール）を含む構造を含む形状誘導型制御放出および保持
WO2022089631A1 (en) * 2020-10-30 2022-05-05 Triastek, Inc. Drug dosage forms for stomach retention
EP4238556A4 (en) * 2020-10-30 2024-09-25 Triastek, Inc. GASTRORETENTIVE PHARMACEUTICAL DOSAGE FORM
HUE067496T2 (hu) 2020-12-08 2024-10-28 Ruminant Biotech Corp Ltd Az állatoknak szánt anyagok bejuttatására szolgáló eszközök és módszerek fejlesztése
WO2022195476A1 (en) 2021-03-15 2022-09-22 Clexio Biosciences Ltd. Gastroretentive devices for assessment of intragastric conditions
CA3229117A1 (en) 2021-08-19 2023-02-23 Dorit MIMROD Method of treating parkinson's disease
JP7832721B2 (ja) * 2022-06-03 2026-03-18 ジュニオン ラブズ ピーティーイー． リミテッド 経口投与用の胃内滞留装置
EP4604932A1 (en) * 2022-10-18 2025-08-27 Triastek, Inc. Oral drug dosage forms for stomach retention
AU2023366929A1 (en) 2022-10-25 2025-05-08 Veradermics, Incorporated Compositions and methods of use for modified release minoxidil
DK181895B1 (en) * 2022-10-28 2025-03-07 Biograil ApS Oral drug delivery device
EP4611722A1 (en) * 2022-11-01 2025-09-10 Merck Sharp & Dohme LLC Gastroretentive systems and methods of making and using same
WO2025043032A1 (en) * 2023-08-21 2025-02-27 Blaesi Aron H Fluid-absorptive gastroretentive dosage form for prolonged drug delivery
WO2025148850A1 (zh) * 2024-01-09 2025-07-17 厦门君德医药科技有限公司 一种胃滞留装置
TW202600188A (zh) * 2024-03-15 2026-01-01 大陸商南京三迭紀醫藥科技有限公司 用於體內滯留的藥物劑型

Family Cites Families (42)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1318259A (en) 1919-10-07 Resilient wheel
AU449029B2 (en) 1969-08-28 1974-04-17 Commonwealth Scientific And Industrial Research Organisation Device for administration to ruminants
US4220153A (en) 1978-05-08 1980-09-02 Pfizer Inc. Controlled release delivery system
JPS6226215A (ja) * 1985-05-10 1987-02-04 メルク　エンド　カムパニ−　インコ−ポレ−テツド 一定に制御した時間内胃中に保持できる薬剤移送装置
CA1273872A (en) 1985-05-10 1990-09-11 Larry J. Caldwell Drug delivery device which can be retained in the stomach for a controlled period of time
US4735804A (en) * 1985-05-10 1988-04-05 Merck & Co., Inc. Drug delivery device which can be retained in the stomach for a controlled period of time
US4767627A (en) 1985-05-29 1988-08-30 Merck & Co., Inc. Drug delivery device which can be retained in the stomach for a controlled period of time
US5002772A (en) * 1988-05-31 1991-03-26 Pfizer Inc. Gastric retention system for controlled drug release
JPH03163011A (ja) 1989-08-31 1991-07-15 Yamanouchi Pharmaceut Co Ltd 胃内滞留デバイス
IT1282650B1 (it) 1996-02-19 1998-03-31 Jagotec Ag Compressa farmaceutica,caratterizzata da elevato aumento di volume a contatto con liquidi biologici
IL133196A0 (en) 1999-11-29 2001-03-19 Yissum Res Dev Co Gastroretentive controlled release pharmaceutical dosage forms
US6753011B2 (en) 2000-01-14 2004-06-22 Osmotica Corp Combined diffusion/osmotic pumping drug delivery system
DE60123384T2 (de) 2000-02-04 2007-08-02 DepoMed, Inc., Menlo Park Dosierungsform des typs "hülle und kern" mit einer wirkstofffreisetzung, die sich der nullten ordnung annähert
AR030557A1 (es) 2000-04-14 2003-08-27 Jagotec Ag Una tableta en multicapa de liberacion controlada y metodo de tratamiento
US6488962B1 (en) 2000-06-20 2002-12-03 Depomed, Inc. Tablet shapes to enhance gastric retention of swellable controlled-release oral dosage forms
CA2409552A1 (en) 2001-10-25 2003-04-25 Depomed, Inc. Gastric retentive oral dosage form with restricted drug release in the lower gastrointestinal tract
US6723340B2 (en) 2001-10-25 2004-04-20 Depomed, Inc. Optimal polymer mixtures for gastric retentive tablets
US20050202090A1 (en) 2002-01-03 2005-09-15 Clarke Allan J. Novel pharmaceutical dosage forms and method for producing same
GB0214013D0 (en) 2002-06-18 2002-07-31 Euro Celtique Sa Pharmaceutical product
US20050013863A1 (en) 2003-07-18 2005-01-20 Depomed, Inc., A Corporation Of The State Of California Dual drug dosage forms with improved separation of drugs
IL166183A0 (en) 2005-01-06 2006-01-15 Yissum Res Dev Co Novel diagnostic and imaging techniques of the gi tract
CA2635313C (en) 2005-12-29 2013-12-31 Osmotica Corp. Triple combination release multi-layered tablet
EP2997953B1 (en) 2006-01-18 2018-12-26 Intec Pharma Ltd. Delivery device for oral intake of an agent
WO2007093999A1 (en) 2006-02-15 2007-08-23 Intec Pharma Ltd. A gastro-retentive system for the delivery of macromolecules
WO2007106957A1 (en) 2006-03-21 2007-09-27 Laboratoires Smb S.A. Multiple units controlled-release floating dosage forms
US9579227B2 (en) * 2006-03-29 2017-02-28 Eat Little Inc. Ingestible implement for weight control
CA2673485A1 (en) 2007-01-15 2008-07-24 Kissei Pharmaceutical Co., Ltd. Gastric retention-type sustained-release levodopa preparation
EP2219624A2 (en) 2007-11-08 2010-08-25 Glaxo Group Limited Pharmaceutical formulations
CN102149369B (zh) 2008-04-18 2016-08-10 因泰克制药有限公司 卡比多巴/左旋多巴胃滞留给药
EP2133071A1 (en) 2008-06-09 2009-12-16 Université de la Méditerranée Process for making gastroretentive dosage forms
US20110268666A1 (en) 2008-09-29 2011-11-03 Yissum Research Development Company of the Research University of Jerusalem, Ltd. Novel gastroretentive delivery system
US20110066175A1 (en) 2009-05-07 2011-03-17 Rainbow Medical Ltd. Gastric anchor
EP2490677A2 (en) 2009-10-19 2012-08-29 Intec Pharma Ltd. Novel gastroretentive dosage forms of poorly soluble drugs
WO2011090724A2 (en) 2009-12-29 2011-07-28 Impax Laboratories, Inc. Gastroretentive solid oral dosage forms with lipid-based low-density excipient
WO2012006963A1 (zh) 2010-07-16 2012-01-19 Zhong Shuguang 在控释制剂中的聚合物增强剂
CN101919803A (zh) 2010-07-16 2010-12-22 钟术光 一种控释制剂
WO2012059815A1 (en) 2010-11-01 2012-05-10 Intec Pharma Ltd. Accordion pill comprising levodopa for an improved treatment of parkinson's disease symptoms
US20130072869A1 (en) 2011-09-15 2013-03-21 The Johns Hopkins University Intra-Gastric Timed-Release Drug Delivery System
WO2013054285A1 (en) 2011-10-11 2013-04-18 Ranbaxy Laboratories Limited A gastroretentive dosage system and process of preparation thereof
WO2015187746A1 (en) * 2014-06-02 2015-12-10 Teva Pharmaceutical Industries Ltd. Expandable gastroretentive dosage form
NZ727659A (en) 2014-06-11 2021-12-24 Massachusetts Inst Technology Residence structures and related methods
CA3006999A1 (en) * 2015-12-01 2017-06-08 Clexio Biosciences Ltd. Gastric retentive devices

Also Published As

Publication number Publication date
JP6570043B2 (ja) 2019-09-04
IL248939B (en) 2021-06-30
US20200405635A1 (en) 2020-12-31
KR20170015389A (ko) 2017-02-08
CN106535878B (zh) 2022-11-01
IL248939A0 (en) 2017-01-31
BR112016028180A2 (pt) 2017-08-22
CN106535878A (zh) 2017-03-22
EP3148514A4 (en) 2018-02-07
US20190365646A1 (en) 2019-12-05
CA2949372A1 (en) 2015-12-10
AU2015271808A1 (en) 2016-12-08
EP3148514A1 (en) 2017-04-05
US20220202708A1 (en) 2022-06-30
JP2017518308A (ja) 2017-07-06
EP3148514B1 (en) 2024-04-17
US11285102B2 (en) 2022-03-29
US11648198B2 (en) 2023-05-16
RU2016151697A (ru) 2018-07-10
MX2016015891A (es) 2017-07-11
CA2949372C (en) 2023-08-22
IL281584B (en) 2022-05-01
IL281584A (en) 2021-05-31
US20150342877A1 (en) 2015-12-03
US10485758B2 (en) 2019-11-26
US20220160630A1 (en) 2022-05-26
US20220202709A1 (en) 2022-06-30
US20220211617A1 (en) 2022-07-07
WO2015187746A1 (en) 2015-12-10

Similar Documents

Publication Publication Date Title
CL2016003055A1 (es) Sistema gastroretentivo expandible de liberación de medicamentos
UY4595S (es) Dispositivo portátil de administración de fármacos
DK3984570T3 (da) Lægemiddelleveringsindretning
EP2982052A4 (en) SWITCHES FOR NETWORK-BASED DIRECT DETECTION OF DEVICES
DK3703785T3 (da) Lægemiddelindgivelsesanordning
EP3554431A4 (en) FEMALE URINARY DEVICE
EP4033741C0 (en) MOBILE TERMINAL
EP3705361A4 (en) BATTERY REPLACEMENT DEVICE
CO6870010A2 (es) Sistema y método para regular el límite del ancho de banda proporcionado a un dispositivo móvil
MX2017008519A (es) Sistema y metodos de camara inalambrica.
EP3573104A4 (en) LIGHT RECEPTION ELEMENT, IMAGING ELEMENT AND IMAGING DEVICE
PL3684300T3 (pl) Urządzenie stomijne
HUE046403T2 (hu) Nõgyógyászati modul és készülék
EP3579302A4 (en) SEPARATOR AND ELECTROCHEMICAL DEVICE THEREFOR
IL280184A (en) Drug delivery devices
EP3751935A4 (en) MOBILE STATION DEVICE
DK3410412T3 (da) Mobil alarmanordning
EP3817122A4 (en) BATTERY DEVICE
DK3914321T3 (da) Lægemiddeladministrationsanordning
PL3807153T3 (pl) Ruchome urządzenie do owijania
EP3846746C0 (en) FEMALE URINARY DEVICE
EP3888527A4 (en) Ophthalmological device
DK3681564T3 (da) Lægemiddeladministrationsanordning
EP3840659C0 (en) WIRELESS ULTRASONIC MONITORING DEVICE
EP3846885C0 (en) DRUG DELIVERY DEVICE