CL2017001466A1 - Un proceso para la fabricación de idalopirdina - Google Patents

Un proceso para la fabricación de idalopirdina

Info

Publication number: CL2017001466A1
Authority: CL; Chile
Prior art keywords: idalopirdine; manufacture; idalopiridine; preparation; pharmaceutically acceptable
Prior art date: 2014-12-12

Application number

CL2017001466A

Other languages

English (en)

Spanish (es)

Inventor

Mikkel Fog Jacobsen

Ole Nielsen

Original Assignee

H Lundbeck As

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2014-12-12

Filing date

2017-06-08

Publication date

2018-01-05

2017-06-08 Application filed by H Lundbeck As filed Critical H Lundbeck As

2018-01-05 Publication of CL2017001466A1 publication Critical patent/CL2017001466A1/es

Links

238000000034 method Methods 0.000 title abstract 2
YBAWYTYNMZWMMJ-UHFFFAOYSA-N 2-(6-fluoro-1h-indol-3-yl)-n-[[3-(2,2,3,3-tetrafluoropropoxy)phenyl]methyl]ethanamine Chemical compound FC(F)C(F)(F)COC1=CC=CC(CNCCC=2C3=CC=C(F)C=C3NC=2)=C1 YBAWYTYNMZWMMJ-UHFFFAOYSA-N 0.000 title 1
229950005109 idalopirdine Drugs 0.000 title 1
238000004519 manufacturing process Methods 0.000 title 1
150000003839 salts Chemical class 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
- C07D209/16—Tryptamines
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
- A61K31/404—Indoles, e.g. pindolol
- A61K31/405—Indole-alkanecarboxylic acids; Derivatives thereof, e.g. tryptophan, indomethacin
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/08—Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Indole Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

CL2017001466A 2014-12-12 2017-06-08 Un proceso para la fabricación de idalopirdina CL2017001466A1 (es)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
DKPA201400721		2014-12-12

Publications (1)

Publication Number	Publication Date
CL2017001466A1 true CL2017001466A1 (es)	2018-01-05

Family

ID=59011415

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
CL2017001466A CL2017001466A1 (es)	2014-12-12	2017-06-08	Un proceso para la fabricación de idalopirdina

Country Status (13)

Country	Link
EP (1)	EP3230265A1 (fr)
JP (1)	JP2017537128A (fr)
KR (1)	KR20170093821A (fr)
CN (1)	CN107001266A (fr)
AU (1)	AU2015359347A1 (fr)
BR (1)	BR112017012021A2 (fr)
CA (1)	CA2968770A1 (fr)
CL (1)	CL2017001466A1 (fr)
CO (1)	CO2017005357A2 (fr)
IL (1)	IL252471A0 (fr)
MA (1)	MA41148A (fr)
MX (1)	MX2017007510A (fr)
RU (1)	RU2017120216A (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US10196363B2 (en)	2014-12-12	2019-02-05	Japan Tobacco Inc.	Dihydropyrimidin-2-one compounds and medical use thereof

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3042685A (en) *		1962-07-03		Process of making g-fluoro tryptamine
PE20081889A1 (es) *	2007-03-23	2009-03-05	Smithkline Beecham Corp	Indol carboxamidas como inhibidores de ikk2
TW201139370A (en) *	2009-12-23	2011-11-16	Lundbeck & Co As H	Processes for the manufacture of a pharmaceutically active agent

2015
- 2015-12-09 MA MA041148A patent/MA41148A/fr unknown
- 2015-12-10 MX MX2017007510A patent/MX2017007510A/es unknown
- 2015-12-10 EP EP15821029.4A patent/EP3230265A1/fr not_active Withdrawn
- 2015-12-10 RU RU2017120216A patent/RU2017120216A/ru not_active Application Discontinuation
- 2015-12-10 CN CN201580065028.6A patent/CN107001266A/zh active Pending
- 2015-12-10 KR KR1020177015206A patent/KR20170093821A/ko not_active Withdrawn
- 2015-12-10 JP JP2017531139A patent/JP2017537128A/ja active Pending
- 2015-12-10 AU AU2015359347A patent/AU2015359347A1/en not_active Abandoned
- 2015-12-10 BR BR112017012021A patent/BR112017012021A2/pt not_active Application Discontinuation
- 2015-12-10 CA CA2968770A patent/CA2968770A1/fr not_active Abandoned
2017
- 2017-05-23 IL IL252471A patent/IL252471A0/en unknown
- 2017-05-26 CO CONC2017/0005357A patent/CO2017005357A2/es unknown
- 2017-06-08 CL CL2017001466A patent/CL2017001466A1/es unknown

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US10196363B2 (en)	2014-12-12	2019-02-05	Japan Tobacco Inc.	Dihydropyrimidin-2-one compounds and medical use thereof

Also Published As

Publication number	Publication date
JP2017537128A (ja)	2017-12-14
CA2968770A1 (fr)	2016-06-16
AU2015359347A1 (en)	2017-06-08
CO2017005357A2 (es)	2017-09-20
IL252471A0 (en)	2017-07-31
MA41148A (fr)	2017-10-17
BR112017012021A2 (pt)	2018-03-13
CN107001266A (zh)	2017-08-01
KR20170093821A (ko)	2017-08-16
MX2017007510A (es)	2017-08-22
RU2017120216A (ru)	2019-01-15
EP3230265A1 (fr)	2017-10-18

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