CL2019000312A1 - Un método de producción de ácido láctico - Google Patents
Un método de producción de ácido lácticoInfo
- Publication number
- CL2019000312A1 CL2019000312A1 CL2019000312A CL2019000312A CL2019000312A1 CL 2019000312 A1 CL2019000312 A1 CL 2019000312A1 CL 2019000312 A CL2019000312 A CL 2019000312A CL 2019000312 A CL2019000312 A CL 2019000312A CL 2019000312 A1 CL2019000312 A1 CL 2019000312A1
- Authority
- CL
- Chile
- Prior art keywords
- lactic acid
- whey
- fermentation broth
- precipitate
- permeate
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23C—DAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; PREPARATION THEREOF
- A23C21/00—Whey; Whey preparations
- A23C21/02—Whey; Whey preparations containing, or treated with, microorganisms or enzymes
- A23C21/026—Whey; Whey preparations containing, or treated with, microorganisms or enzymes containing, or treated only with, lactic acid producing bacteria, bifidobacteria or propionic acid bacteria
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23C—DAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; PREPARATION THEREOF
- A23C9/00—Milk preparations; Milk powder or milk powder preparations
- A23C9/14—Milk preparations; Milk powder or milk powder preparations in which the chemical composition of the milk is modified by non-chemical treatment
- A23C9/142—Milk preparations; Milk powder or milk powder preparations in which the chemical composition of the milk is modified by non-chemical treatment by dialysis, reverse osmosis or ultrafiltration
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D61/00—Processes of separation using semi-permeable membranes, e.g. dialysis, osmosis or ultrafiltration; Apparatus, accessories or auxiliary operations specially adapted therefor
- B01D61/14—Ultrafiltration; Microfiltration
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D61/00—Processes of separation using semi-permeable membranes, e.g. dialysis, osmosis or ultrafiltration; Apparatus, accessories or auxiliary operations specially adapted therefor
- B01D61/58—Multistep processes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
- C12P7/56—Lactic acid
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23C—DAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; PREPARATION THEREOF
- A23C2210/00—Physical treatment of dairy products
- A23C2210/20—Treatment using membranes, including sterile filtration
- A23C2210/206—Membrane filtration of a permeate obtained by ultrafiltration, nanofiltration or microfiltration
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D2311/00—Details relating to membrane separation process operations and control
- B01D2311/04—Specific process operations in the feed stream; Feed pretreatment
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D2311/00—Details relating to membrane separation process operations and control
- B01D2311/06—Specific process operations in the permeate stream
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D2311/00—Details relating to membrane separation process operations and control
- B01D2311/26—Further operations combined with membrane separation processes
- B01D2311/2623—Ion-Exchange
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D2311/00—Details relating to membrane separation process operations and control
- B01D2311/26—Further operations combined with membrane separation processes
- B01D2311/2642—Aggregation, sedimentation, flocculation, precipitation or coagulation
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D2311/00—Details relating to membrane separation process operations and control
- B01D2311/26—Further operations combined with membrane separation processes
- B01D2311/2673—Evaporation
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D2311/00—Details relating to membrane separation process operations and control
- B01D2311/26—Further operations combined with membrane separation processes
- B01D2311/2688—Biological processes
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D61/00—Processes of separation using semi-permeable membranes, e.g. dialysis, osmosis or ultrafiltration; Apparatus, accessories or auxiliary operations specially adapted therefor
- B01D61/02—Reverse osmosis; Hyperfiltration ; Nanofiltration
- B01D61/025—Reverse osmosis; Hyperfiltration
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D69/00—Semi-permeable membranes for separation processes or apparatus characterised by their form, structure or properties; Manufacturing processes specially adapted therefor
- B01D69/02—Semi-permeable membranes for separation processes or apparatus characterised by their form, structure or properties; Manufacturing processes specially adapted therefor characterised by their properties
Landscapes
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Water Supply & Treatment (AREA)
- Microbiology (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Polymers & Plastics (AREA)
- Food Science & Technology (AREA)
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Biotechnology (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Dairy Products (AREA)
- Separation Using Semi-Permeable Membranes (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Abstract
Se describe un proceso para producir ácido láctico puro a partir de un subproducto de suero rico en lactosa y minerales, por ejemplo, deslactado por qué el permeado o el concentrado de suero permeado. El método comprende etapas anteriores de neutralizar el subproducto de suero con un hidróxido metálico básico para formar un precipitado que comprende calcio y fosfato, y separar el precipitado del subproducto de suero para proporcionar un subproducto de suero clarificado. El subproducto de suero de leche clarificado es fermentado por una bacteria capaz de bioconversión de lactosa a ácido láctico para proporcionar un caldo de fermentación que contiene una sal de ácido láctico. En las etapas posteriores, el caldo de fermentación se acidifica para liberar ácido láctico de la sal del ácido láctico, se elimina el precipitado del caldo producido por acidificación y el caldo de fermentación acidificado se trata para recuperar el ácido láctico puro mediante la eliminación de las sales residuales y el agua. , y opcionalmente la proteína. El proceso de la invención produce ácido láctico con una pureza de 80-98% y una pureza isomérica> 98% de ácido L-láctico utilizando un proceso que emplea la eliminación aguas arriba de sales divalentes por precipitación química, fermentación bacteriana del sustrato desmineralizado y Procesamiento posterior mínimo del caldo de fermentación. Los métodos de la invención también pueden emplearse con permeados de leche.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP16183196.1A EP3282018A1 (en) | 2016-08-08 | 2016-08-08 | A method of producing lactic acid |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CL2019000312A1 true CL2019000312A1 (es) | 2019-06-21 |
Family
ID=56681979
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CL2019000312A CL2019000312A1 (es) | 2016-08-08 | 2019-02-06 | Un método de producción de ácido láctico |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US11382335B2 (es) |
| EP (2) | EP3282018A1 (es) |
| AU (1) | AU2017309957B2 (es) |
| BR (1) | BR112019002462A2 (es) |
| CL (1) | CL2019000312A1 (es) |
| DK (1) | DK3497225T3 (es) |
| ES (1) | ES2883329T3 (es) |
| MX (1) | MX2019001560A (es) |
| NZ (1) | NZ750378A (es) |
| PL (1) | PL3497225T3 (es) |
| PT (1) | PT3497225T (es) |
| RU (1) | RU2763351C2 (es) |
| WO (1) | WO2018029219A1 (es) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2017072748A1 (en) | 2015-10-30 | 2017-05-04 | Glanbia Ingredients Ireland Limited | A method for producing lactic acid by bacterial fermentation |
| EP3282018A1 (en) | 2016-08-08 | 2018-02-14 | Glanbia Ingredients Ireland Designated Activity Company | A method of producing lactic acid |
| AU2020224691B2 (en) * | 2019-02-24 | 2022-10-20 | Capro-X, Inc. | Microbial conversion of lactose-containing feedstocks to carboxylic acids |
| EP4574984A1 (en) * | 2023-12-21 | 2025-06-25 | Tirlán Limited | A method of producing organic acids or salts thereof |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3131717A1 (de) * | 1981-08-11 | 1983-03-03 | Hoechst Ag, 6000 Frankfurt | Lactobacillus bulgaricus dsm 2129 und seine verwendung zur herstellung von d-milchsaeure |
| US4698303A (en) * | 1985-02-15 | 1987-10-06 | Engenics, Inc. | Production of lactic acid by continuous fermentation using an inexpensive raw material and a simplified method of lactic acid purification |
| US5322781A (en) * | 1985-11-18 | 1994-06-21 | Cooperatieve Weiproduktenfabriek "Borculo" W.A. | Procedure for the preparation of D-(-)-lactic acid with Lactobacillus bulgaricus |
| US5416020A (en) * | 1992-09-29 | 1995-05-16 | Bio-Technical Resources | Lactobacillus delbrueckii ssp. bulgaricus strain and fermentation process for producing L-(+)-lactic acid |
| BR9605262A (pt) | 1995-10-27 | 1998-07-21 | Shimadzu Corp | Método para a produçao de ácido lático com alta pureza óptica usando cepas de bacillus |
| AUPO821397A0 (en) * | 1997-07-24 | 1997-08-14 | Commonwealth Scientific And Industrial Research Organisation | Process for the purification of nutrients from food process streams |
| WO2001092555A1 (en) * | 2000-05-30 | 2001-12-06 | Lactascan Aps | Method for producing lactic acid |
| WO2010103548A2 (en) | 2009-03-13 | 2010-09-16 | Godavari Biorefineries Ltd. | Improved method for producing lactic acid and derivative thereof |
| WO2011159629A2 (en) * | 2010-06-14 | 2011-12-22 | Cobalt Technologies, Inc. | Salt selection of microbial mutants to increase bioproduct tolerance, titer, or osmotic shock tolerance |
| WO2017072748A1 (en) | 2015-10-30 | 2017-05-04 | Glanbia Ingredients Ireland Limited | A method for producing lactic acid by bacterial fermentation |
| EP3282018A1 (en) | 2016-08-08 | 2018-02-14 | Glanbia Ingredients Ireland Designated Activity Company | A method of producing lactic acid |
-
2016
- 2016-08-08 EP EP16183196.1A patent/EP3282018A1/en not_active Withdrawn
-
2017
- 2017-08-08 PT PT177614476T patent/PT3497225T/pt unknown
- 2017-08-08 EP EP17761447.6A patent/EP3497225B1/en active Active
- 2017-08-08 DK DK17761447.6T patent/DK3497225T3/da active
- 2017-08-08 PL PL17761447T patent/PL3497225T3/pl unknown
- 2017-08-08 RU RU2019102326A patent/RU2763351C2/ru active
- 2017-08-08 US US16/324,117 patent/US11382335B2/en active Active
- 2017-08-08 ES ES17761447T patent/ES2883329T3/es active Active
- 2017-08-08 NZ NZ750378A patent/NZ750378A/en unknown
- 2017-08-08 MX MX2019001560A patent/MX2019001560A/es unknown
- 2017-08-08 WO PCT/EP2017/070120 patent/WO2018029219A1/en not_active Ceased
- 2017-08-08 BR BR112019002462-0A patent/BR112019002462A2/pt not_active Application Discontinuation
- 2017-08-08 AU AU2017309957A patent/AU2017309957B2/en active Active
-
2019
- 2019-02-06 CL CL2019000312A patent/CL2019000312A1/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| US20190166865A1 (en) | 2019-06-06 |
| RU2019102326A (ru) | 2020-09-11 |
| RU2019102326A3 (es) | 2021-02-08 |
| EP3497225A1 (en) | 2019-06-19 |
| AU2017309957A1 (en) | 2019-02-21 |
| US11382335B2 (en) | 2022-07-12 |
| EP3497225B1 (en) | 2021-05-05 |
| NZ750378A (en) | 2026-01-30 |
| RU2763351C2 (ru) | 2021-12-28 |
| BR112019002462A2 (pt) | 2019-05-14 |
| AU2017309957B2 (en) | 2022-01-27 |
| MX2019001560A (es) | 2019-09-18 |
| EP3282018A1 (en) | 2018-02-14 |
| WO2018029219A1 (en) | 2018-02-15 |
| ES2883329T3 (es) | 2021-12-07 |
| DK3497225T3 (da) | 2021-08-09 |
| PL3497225T3 (pl) | 2022-03-21 |
| PT3497225T (pt) | 2021-08-11 |
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